[go: up one dir, main page]

EA201391419A1 - Пролекарства d-изоглутамил-[d/l]-триптофана - Google Patents

Пролекарства d-изоглутамил-[d/l]-триптофана

Info

Publication number
EA201391419A1
EA201391419A1 EA201391419A EA201391419A EA201391419A1 EA 201391419 A1 EA201391419 A1 EA 201391419A1 EA 201391419 A EA201391419 A EA 201391419A EA 201391419 A EA201391419 A EA 201391419A EA 201391419 A1 EA201391419 A1 EA 201391419A1
Authority
EA
Eurasian Patent Office
Prior art keywords
triptophana
prolargers
izoglutamyl
compounds
methods
Prior art date
Application number
EA201391419A
Other languages
English (en)
Inventor
Тим Фэт Тэм
Реджис Леунг-Тоунг
Иншэн Ван
Яньцин Чжао
Тао Синь
Вэнрен Ли
Йоланта Мария Водзинска
Враджлал С. Рабадия
Кристофер Джон Фини
Original Assignee
Апотекс Текнолоджиз Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Апотекс Текнолоджиз Инк. filed Critical Апотекс Текнолоджиз Инк.
Publication of EA201391419A1 publication Critical patent/EA201391419A1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Transplantation (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Предоставлены соединения, которые представляют собой пролекарства D-изоглутамил-[D/L]-триптофана, способы получения соединений и способы использования соединений.
EA201391419A 2011-03-31 2012-03-30 Пролекарства d-изоглутамил-[d/l]-триптофана EA201391419A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161470467P 2011-03-31 2011-03-31
PCT/CA2012/000304 WO2012129671A1 (en) 2011-03-31 2012-03-30 Prodrugs of d-isoglutamyl-[d/l]-tryptophan

Publications (1)

Publication Number Publication Date
EA201391419A1 true EA201391419A1 (ru) 2014-02-28

Family

ID=46929258

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201391419A EA201391419A1 (ru) 2011-03-31 2012-03-30 Пролекарства d-изоглутамил-[d/l]-триптофана

Country Status (9)

Country Link
US (1) US20140343050A1 (ru)
EP (1) EP2691369A4 (ru)
JP (1) JP2014509613A (ru)
CN (1) CN103502214A (ru)
AU (1) AU2012234680A1 (ru)
CA (1) CA2831427A1 (ru)
EA (1) EA201391419A1 (ru)
WO (1) WO2012129671A1 (ru)
ZA (1) ZA201307229B (ru)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3030512B1 (fr) 2014-12-18 2018-03-30 L'oreal Utilisation comme agent deodorant et/ou parfumant de derives esters du l-tryptophane
CN112142746B (zh) 2019-06-28 2021-09-24 四川大学华西医院 苯二氮卓类化合物及其制备方法和在医药上的作用
JP7440939B2 (ja) * 2020-08-13 2024-02-29 南京海融医薬科技股▲フン▼有限公司 イブプロフェンエステル系プロドラッグ、医薬組成物、調製方法および使用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2107692C1 (ru) * 1995-06-07 1998-03-27 Дейгин Владислав Исакович Пептид и способ его получения
RU2141483C1 (ru) * 1997-07-04 1999-11-20 Небольсин Владимир Евгеньевич Производные пептидов или их фармацевтически приемлемые соли, способ их получения, применение и фармацевтическая композиция
DE19828113A1 (de) * 1998-06-24 2000-01-05 Probiodrug Ges Fuer Arzneim Prodrugs von Inhibitoren der Dipeptidyl Peptidase IV
CA2569204A1 (en) * 2006-11-28 2008-05-28 Apotex Technologies Inc. Crystalline d-isoglutamyl-d-tryptophan and the mono ammonium salt of d-isoglutamyl-d-tryptophan

Also Published As

Publication number Publication date
AU2012234680A1 (en) 2013-10-17
US20140343050A1 (en) 2014-11-20
WO2012129671A1 (en) 2012-10-04
CA2831427A1 (en) 2012-10-04
EP2691369A1 (en) 2014-02-05
JP2014509613A (ja) 2014-04-21
NZ615880A (en) 2015-05-29
CN103502214A (zh) 2014-01-08
EP2691369A4 (en) 2014-09-10
ZA201307229B (en) 2014-06-25

Similar Documents

Publication Publication Date Title
EA201491811A1 (ru) АНТИ-LgR5 АНТИТЕЛА И ИММУНОКОНЪЮГАТЫ
UY34456A (es) Anticuerpos anti-il-36r
CL2012002979A1 (es) Derivados de n3-sustituido-n1-sulfonil-5-fluorpirimidinona.
UY34602A (es) ?Derivados de bencimidazolil- e imidazopiridinil-metilamina?
UY34206A (es) Anticuerpo monoclonal de interleucina-31
IN2014CN02639A (ru)
CO7020912A2 (es) Inhibidores de bromodominios
EA201391274A1 (ru) Аминохинолины в качестве ингибиторов киназ
UY34885A (es) Proteínas de unión anti-mesotelina
PH12017501176A1 (en) Pyruvate kinase activators for use therapy
UA109931C2 (xx) Піримідинциклогексильні модулятори глюкокортикоїдних рецепторів
UY33977A (es) Híbrido de pigmento autoaglutinante.
CO7091177A2 (es) Inhibidores de la beta-secretasa
GB201321365D0 (en) Methods for performing patterned chemistry
CR20130539A (es) Triazolopiridinas
UY4153Q (es) Batería
UY34071A (es) Micropartícula inyectable de liberación controlada
UY34006A (es) Imidazopiridazinas
MX2015002487A (es) Proceso para la preparacion de teneligliptina.
CL2011002403S1 (es) Luminaria solar.
UY33976A (es) Derivados de pirazolo-pirimidina.
UY34329A (es) Compuestos de triazolopiridina
UY34553A (es) Procedimiento de preparación de la sal de l-arginina de perindoprilo
UY34403A (es) Preparación de liberación sostenida
UY4152Q (es) Batería