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EA201390142A1 - 2'-фторзамещенные карбануклеозидные аналоги для противовирусного лечения - Google Patents

2'-фторзамещенные карбануклеозидные аналоги для противовирусного лечения

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Publication number
EA201390142A1
EA201390142A1 EA201390142A EA201390142A EA201390142A1 EA 201390142 A1 EA201390142 A1 EA 201390142A1 EA 201390142 A EA201390142 A EA 201390142A EA 201390142 A EA201390142 A EA 201390142A EA 201390142 A1 EA201390142 A1 EA 201390142A1
Authority
EA
Eurasian Patent Office
Prior art keywords
carbanulosis
analogs
fluoro
substituted
antiviral treatment
Prior art date
Application number
EA201390142A
Other languages
English (en)
Inventor
Майкл О'Нил Ханрахан Кларк
Чонг У. Ким
Уиллард Лью
Original Assignee
Джилид Сайэнс, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Джилид Сайэнс, Инк. filed Critical Джилид Сайэнс, Инк.
Publication of EA201390142A1 publication Critical patent/EA201390142A1/ru

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    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65586Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom
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    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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Abstract

Предоставлены методы для лечения инфекций Orthomyxoviridae вируса путем введения рибозидов, фосфатов рибозидов и пролекарств формулы Iгде Rпредставляет собой галоген. Предоставленные соединения, композиции и способы являются полезными, в частности, для лечения вирусных инфекций гриппа человека.
EA201390142A 2010-09-13 2011-09-12 2'-фторзамещенные карбануклеозидные аналоги для противовирусного лечения EA201390142A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38214510P 2010-09-13 2010-09-13
PCT/US2011/051249 WO2012037038A1 (en) 2010-09-13 2011-09-12 2' -fluoro substituted carba-nucleoside analogs for antiviral treatment

Publications (1)

Publication Number Publication Date
EA201390142A1 true EA201390142A1 (ru) 2013-09-30

Family

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Application Number Title Priority Date Filing Date
EA201390142A EA201390142A1 (ru) 2010-09-13 2011-09-12 2'-фторзамещенные карбануклеозидные аналоги для противовирусного лечения

Country Status (14)

Country Link
US (3) US20120107274A1 (ru)
EP (1) EP2616080A1 (ru)
JP (1) JP2013541519A (ru)
KR (1) KR20140091459A (ru)
CN (1) CN103153314A (ru)
AR (1) AR082960A1 (ru)
AU (1) AU2011302310A1 (ru)
BR (1) BR112013005888A2 (ru)
CA (1) CA2807584C (ru)
EA (1) EA201390142A1 (ru)
MX (1) MX2013002871A (ru)
TW (1) TW201305185A (ru)
UY (1) UY33600A (ru)
WO (1) WO2012037038A1 (ru)

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BR112013005888A2 (pt) 2016-05-10
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