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EA200601223A1 - Производные сульфонамида для лечения заболеваний - Google Patents

Производные сульфонамида для лечения заболеваний

Info

Publication number
EA200601223A1
EA200601223A1 EA200601223A EA200601223A EA200601223A1 EA 200601223 A1 EA200601223 A1 EA 200601223A1 EA 200601223 A EA200601223 A EA 200601223A EA 200601223 A EA200601223 A EA 200601223A EA 200601223 A1 EA200601223 A1 EA 200601223A1
Authority
EA
Eurasian Patent Office
Prior art keywords
derivatives
diseases
sulfonamide
treatment
disorders
Prior art date
Application number
EA200601223A
Other languages
English (en)
Other versions
EA011167B1 (ru
Inventor
Алан Дэниел Браун
Марк Эдвард Баннэйдж
Пол Алан Глоссоп
Ким Джеймс
Шарлотт Элис Луиз Лейн
Расселл Эндрю Льютвайт
Ян Брайан Моузес
Дэвид Энтони Прайс
Николас Мюррей Томсон
Original Assignee
Пфайзер Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36954179&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA200601223(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB0406387A external-priority patent/GB0406387D0/en
Application filed by Пфайзер Инк. filed Critical Пфайзер Инк.
Publication of EA200601223A1 publication Critical patent/EA200601223A1/ru
Publication of EA011167B1 publication Critical patent/EA011167B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
    • C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C311/08—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/06—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Данное изобретение относится к соединениям формулы (1) и к способам получения таких производных, содержащим их композициям и применению таких производных. Соединения согласно настоящему изобретению пригодны в случае многочисленных заболеваний, нарушений и состояний, в частности воспалительных, аллергических и респираторных заболеваний, нарушений и состояний.
EA200601223A 2004-01-22 2005-01-12 Производные сульфонамида для лечения заболеваний EA011167B1 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP04290169 2004-01-22
GB0406387A GB0406387D0 (en) 2004-03-22 2004-03-22 Sulfonamide derivatives for the treatment of diseases
US60026004P 2004-08-09 2004-08-09
PCT/IB2005/000086 WO2005080313A2 (en) 2004-01-22 2005-01-12 Sulfonamide derivatives for the treatment of diseases

Publications (2)

Publication Number Publication Date
EA200601223A1 true EA200601223A1 (ru) 2006-12-29
EA011167B1 EA011167B1 (ru) 2009-02-27

Family

ID=36954179

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200601223A EA011167B1 (ru) 2004-01-22 2005-01-12 Производные сульфонамида для лечения заболеваний

Country Status (30)

Country Link
US (4) US7244766B2 (ru)
EP (1) EP1708991B1 (ru)
JP (1) JP4020954B2 (ru)
AP (1) AP2359A (ru)
AR (1) AR047509A1 (ru)
AT (1) ATE375977T1 (ru)
AU (1) AU2005214153B2 (ru)
BR (1) BRPI0507085A (ru)
CA (1) CA2553789C (ru)
DE (1) DE602005002930T2 (ru)
DK (1) DK1708991T3 (ru)
DO (1) DOP2005000006A (ru)
EA (1) EA011167B1 (ru)
ES (1) ES2293530T3 (ru)
GE (1) GEP20094781B (ru)
MY (1) MY143390A (ru)
NL (1) NL1028087C2 (ru)
NO (1) NO20062983L (ru)
NZ (1) NZ548318A (ru)
OA (1) OA13362A (ru)
PA (1) PA8622001A1 (ru)
PE (1) PE20051136A1 (ru)
PL (1) PL1708991T3 (ru)
PT (1) PT1708991E (ru)
RS (1) RS50561B (ru)
SI (1) SI1708991T1 (ru)
TW (1) TWI341831B (ru)
UA (1) UA84048C2 (ru)
UY (1) UY28721A1 (ru)
WO (1) WO2005080313A2 (ru)

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GB0425054D0 (en) * 2004-03-23 2004-12-15 Pfizer Ltd Formamide derivatives for the treatment of diseases
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CA2709293A1 (en) * 2005-07-18 2007-01-25 Pfizer Limited Process for the preparation of sulfonamide derivatives
GB0516313D0 (en) 2005-08-08 2005-09-14 Argenta Discovery Ltd Azole derivatives and their uses
BRPI0614290A2 (pt) 2005-08-08 2011-03-22 Argenta Discovery Ltd derivados de biciclo [ 2.2.1 ] hept-7-ilamina e seus usos
GB0601951D0 (en) 2006-01-31 2006-03-15 Novartis Ag Organic compounds
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JP4948913B2 (ja) * 2006-06-16 2012-06-06 上野製薬株式会社 ナフタレンカルボン酸アミドの製造方法
EP2231642B1 (en) 2008-01-11 2013-10-23 Novartis AG Pyrimidines as kinase inhibitors
US8236786B2 (en) 2008-08-07 2012-08-07 Pulmagen Therapeutics (Inflammation) Limited Respiratory disease treatment
NZ594157A (en) 2008-12-30 2013-07-26 Pulmagen Therapeutics Inflammation Ltd Sulfonamide compounds for the treatment of respiratory disorders
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WO2010150014A1 (en) 2009-06-24 2010-12-29 Pulmagen Therapeutics (Inflammation) Limited 5r- 5 -deuterated glitazones for respiratory disease treatment
JP5801997B2 (ja) 2009-07-07 2015-10-28 ファイザー・リミテッドＰｆｉｚｅｒ Ｌｉｍｉｔｅｄ 薬品の組合せを吸入するための投薬ユニット、投薬ユニットのパック、および吸入器
GB0918922D0 (en) 2009-10-28 2009-12-16 Vantia Ltd Aminopyridine derivatives
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WO2011098746A1 (en) 2010-02-09 2011-08-18 Pulmagen Therapeutics (Inflammation) Limited Crystalline acid addition salts of ( 5r) -enanti0mer of pioglitazone
GB201002243D0 (en) 2010-02-10 2010-03-31 Argenta Therapeutics Ltd Respiratory disease treatment
GB201002224D0 (en) 2010-02-10 2010-03-31 Argenta Therapeutics Ltd Respiratory disease treatment
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US8637516B2 (en) 2010-09-09 2014-01-28 Irm Llc Compounds and compositions as TRK inhibitors
PH12013501758A1 (en) 2011-02-25 2013-10-14 Irm Llc Pyrazolo [1,5-a] pyridines as trk inhibitors
WO2013021309A1 (en) 2011-08-11 2013-02-14 Pfizer Limited Intermediate and process for the preparation of a sulfonamide derivative
AU2021296221A1 (en) 2020-06-26 2023-02-02 Mylan Pharma Uk Limited Formulations including 5-(3-(3-hydroxyphenoxy)azetidin-1-yl)-5-methyl-2,2-diphenylhexanamide

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Also Published As

Publication number Publication date
SI1708991T1 (sl) 2008-02-29
NZ548318A (en) 2009-03-31
DE602005002930D1 (de) 2007-11-29
MY143390A (en) 2011-05-13
CA2553789A1 (en) 2005-09-01
TW200530165A (en) 2005-09-16
TWI341831B (en) 2011-05-11
GEP20094781B (en) 2009-09-25
US7528170B2 (en) 2009-05-05
UA84048C2 (ru) 2008-09-10
EP1708991B1 (en) 2007-10-17
PL1708991T3 (pl) 2008-02-29
AP2359A (en) 2012-01-30
PE20051136A1 (es) 2006-02-18
AP2006003669A0 (en) 2006-06-30
EA011167B1 (ru) 2009-02-27
WO2005080313A9 (en) 2006-08-31
US20100273758A1 (en) 2010-10-28
NL1028087C2 (nl) 2006-05-09
DOP2005000006A (es) 2005-07-31
WO2005080313A2 (en) 2005-09-01
PA8622001A1 (es) 2005-08-30
WO2005080313A3 (en) 2005-12-01
AU2005214153B2 (en) 2008-09-18
DK1708991T3 (da) 2008-01-14
JP4020954B2 (ja) 2007-12-12
JP2007518789A (ja) 2007-07-12
EP1708991A2 (en) 2006-10-11
ES2293530T3 (es) 2008-03-16
US20080267970A1 (en) 2008-10-30
US20050182091A1 (en) 2005-08-18
BRPI0507085A (pt) 2007-06-19
US20090197912A1 (en) 2009-08-06
US8013019B2 (en) 2011-09-06
CA2553789C (en) 2011-07-19
US7767715B2 (en) 2010-08-03
NO20062983L (no) 2006-07-24
ATE375977T1 (de) 2007-11-15
DE602005002930T2 (de) 2008-07-24
NL1028087A1 (nl) 2005-07-25
AR047509A1 (es) 2006-01-25
UY28721A1 (es) 2005-08-31
RS50561B (sr) 2010-05-07
OA13362A (en) 2007-04-13
US7244766B2 (en) 2007-07-17
AU2005214153A1 (en) 2005-09-01
PT1708991E (pt) 2007-12-14

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Designated state(s): AM AZ BY KZ KG MD TJ TM RU