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EA200600237A1 - Антипаразитарная композиция - Google Patents

Антипаразитарная композиция

Info

Publication number
EA200600237A1
EA200600237A1 EA200600237A EA200600237A EA200600237A1 EA 200600237 A1 EA200600237 A1 EA 200600237A1 EA 200600237 A EA200600237 A EA 200600237A EA 200600237 A EA200600237 A EA 200600237A EA 200600237 A1 EA200600237 A1 EA 200600237A1
Authority
EA
Eurasian Patent Office
Prior art keywords
closantel
salicylanilide
antiparasitic
antiparasitic composition
bioaccumulation
Prior art date
Application number
EA200600237A
Other languages
English (en)
Other versions
EA009602B1 (ru
Inventor
Уилльям Блэйкли
Лиллиан Кроми
Original Assignee
Норбрук Лэборетериз Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Норбрук Лэборетериз Лимитед filed Critical Норбрук Лэборетериз Лимитед
Publication of EA200600237A1 publication Critical patent/EA200600237A1/ru
Publication of EA009602B1 publication Critical patent/EA009602B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/36—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
    • A01N37/38—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids having at least one oxygen or sulfur atom attached to an aromatic ring system
    • A01N37/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids having at least one oxygen or sulfur atom attached to an aromatic ring system having at least one carboxylic group or a thio analogue, or a derivative thereof, and one oxygen or sulfur atom attached to the same aromatic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/609—Amides, e.g. salicylamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Agronomy & Crop Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Pest Control & Pesticides (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Toxicology (AREA)
  • Road Paving Structures (AREA)

Abstract

Антипаразитарная композиция, представленная как местный продукт, «наносимый путем наливания на участок кожи животного» для лечения животных, зараженных паразитами, известными как восприимчивые к салициланилидам, особенно клозантелу, одному или вместе по крайней мере с одним другим антипаразитарным соединением типа авермектина или милбемицина, и предложения усиленного бионакопления салициланилида путем обеспечения системы доставки, включающей по меньшей мере 20% (объем/объем) одного или более спиртов, и произвольно включающей полимерную часть, выбранную из группы, состоящей из поливинилпирролидона (ПВП), блок-сополимера полиоксипропилена/полиоксиэтилена (полоксамера), и полиэтиленгликолей (ПЭГ), таким образом улучшая бионакопление, например, клозантела (как оценено относительно уровней клозантела в плазме крови).
EA200600237A 2003-07-12 2004-07-12 Антипаразитарная композиция EA009602B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0316377.1A GB0316377D0 (en) 2003-07-12 2003-07-12 Parasiticidal composition
PCT/GB2004/003006 WO2005007241A1 (en) 2003-07-12 2004-07-12 Parasiticidal composition

Publications (2)

Publication Number Publication Date
EA200600237A1 true EA200600237A1 (ru) 2006-06-30
EA009602B1 EA009602B1 (ru) 2008-02-28

Family

ID=27742085

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200600237A EA009602B1 (ru) 2003-07-12 2004-07-12 Антипаразитарная композиция

Country Status (28)

Country Link
US (1) US8993546B2 (ru)
EP (2) EP2286876A1 (ru)
JP (1) JP4677405B2 (ru)
KR (1) KR101095419B1 (ru)
CN (1) CN1822880B (ru)
AP (1) AP2956A (ru)
AU (1) AU2004257450B2 (ru)
BR (1) BRPI0412522A (ru)
CA (1) CA2532199C (ru)
CR (1) CR8174A (ru)
DK (1) DK1646425T3 (ru)
EA (1) EA009602B1 (ru)
EC (1) ECSP066360A (ru)
ES (1) ES2390224T3 (ru)
GB (2) GB0316377D0 (ru)
GE (1) GEP20094648B (ru)
HR (1) HRP20120721T1 (ru)
IL (1) IL173057A (ru)
MX (1) MXPA06000135A (ru)
NO (1) NO336181B1 (ru)
NZ (1) NZ544973A (ru)
OA (1) OA13188A (ru)
PL (1) PL1646425T3 (ru)
PT (1) PT1646425E (ru)
SI (1) SI1646425T1 (ru)
TN (1) TNSN06006A1 (ru)
WO (1) WO2005007241A1 (ru)
ZA (1) ZA200600374B (ru)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002952597A0 (en) * 2002-11-11 2002-11-28 Schering-Plough Pty. Limited Topical parasiticide formulations and methods of treatment
GB0501220D0 (en) * 2005-01-21 2005-03-02 Norbrook Lab Ltd Anthelmintic composition
GB0711957D0 (en) * 2007-06-21 2007-08-01 Syntopix Ltd Formulations
CN101693009B (zh) * 2009-10-27 2010-12-01 纽素乐必佳（天津）药业集团有限公司 牛羊用抗寄生虫病氯氰碘柳胺钠透皮溶液及其制备方法
FR2991173B1 (fr) 2012-06-04 2015-11-06 Virbac Composition veterinaire a administration cutanee a base d'oxyclozanide
CN103720652B (zh) * 2014-01-07 2016-09-28 王玉万 用泊洛沙姆和油性介质制备含阿维菌素类药物注射剂
WO2019054967A2 (en) * 2017-03-15 2019-03-21 Verano Ilac Sanayi Ve Ticaret Anonim Sirketi VETERINARY COMPOSITION TO BE POURED COMPRISING EPRINOMECTIN
GB201715122D0 (en) * 2017-09-19 2017-11-01 Omnipharm Dev Ltd Topical anti-infective formulation
JP7584421B2 (ja) * 2018-10-12 2024-11-15 ホビオネ サイエンティア リミテッド 大環状ラクトン製剤、その調製方法、及び眼部寄生虫に続発する症状の治療における該製剤の使用

Family Cites Families (35)

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US3798258A (en) * 1970-03-13 1974-03-19 Merck & Co Inc Salicylanilides
LU62350A1 (ru) * 1970-12-31 1972-08-23
US3950360A (en) 1972-06-08 1976-04-13 Sankyo Company Limited Antibiotic substances
US4005218A (en) 1975-03-18 1977-01-25 Janssen Pharmaceutica N.V. Antiparasitic salicylanilide derivatives
SE434277B (sv) 1976-04-19 1984-07-16 Merck & Co Inc Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
US4206205A (en) 1977-10-03 1980-06-03 Merck & Co., Inc. Monosaccharide and aglycone derivatives of C-076
US4201861A (en) 1977-10-03 1980-05-06 Merck & Co., Inc. Acyl derivatives of C-076 compounds
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US4171314A (en) 1977-12-19 1979-10-16 Merck & Co., Inc. 13-Halo and 13-deoxy C-076 compounds
NZ197796A (en) 1980-08-04 1984-11-09 Merck & Co Inc Stabilised aqueous formulations containing ivermectin
NZ210505A (en) 1983-12-22 1988-06-30 Merck & Co Inc Parasiticidal compositions containing avermectin or milbemycin derivatives
NZ335166A (en) 1999-04-14 2001-11-30 Ashmont Holdings Ltd Anthelmintic composition containing triclabendazole in at least one solvent
RU2033150C1 (ru) 1992-06-10 1995-04-20 Виктор Антонович Дриняев Препарат для лечения и профилактики псороптоза у животных "аверсект"
PL174488B1 (pl) * 1993-05-10 1998-08-31 Merck & Co Inc Preparat do zwalczania pasożytów zwierząt oraz sposób wytwarzania preparatu do zwalczania pasożytów zwierząt
ES2170099T3 (es) * 1993-05-26 2002-08-01 Commw Scient Ind Res Org Composiciones antiparasitarias.
EP0710105B1 (en) 1993-06-15 2003-07-30 The Australian National University Synergistic anthelmintic compositions against fasciola hepatica and other fasciola species
NZ248486A (en) * 1993-08-24 1996-07-26 Ashmont Holdings Limited Subst Stable anthelmintic formulation containing closantel and one or more avermectins or milbemycins in a glycol based solvent
FR2739778B1 (fr) * 1995-10-13 1997-12-12 Virbac Lab Formulation topique destinee a traiter la maladie de la douve du foie chez l'animal
RU2112508C1 (ru) 1995-12-26 1998-06-10 Писков Вячеслав Борисович Способ лечения и профилактики саркоптоидозов животных
RU2121831C1 (ru) 1997-08-01 1998-11-20 Анатолий Александрович Непоклонов Препарат для профилактики и лечения гиподерматоза крупного рогатого скота
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GB2386067A (en) * 2002-02-28 2003-09-10 Norbrook Lab Ltd Long-acting parasiticidal composition with improved bioavailability comprising an avermectin or milbemycin, plus a salicylanilide & a polymeric species
AU2002952597A0 (en) * 2002-11-11 2002-11-28 Schering-Plough Pty. Limited Topical parasiticide formulations and methods of treatment
AU2003275779B2 (en) * 2002-11-11 2009-02-05 Schering-Plough Pty. Limited Topical parasiticide formulations and methods of treatment
AU2003900505A0 (en) * 2003-02-05 2003-02-20 Jurox Pty Ltd Anthelmintic composition

Also Published As

Publication number Publication date
GB2403905B (en) 2005-12-14
ZA200600374B (en) 2007-05-30
NZ544973A (en) 2008-09-26
WO2005007241A1 (en) 2005-01-27
ECSP066360A (es) 2006-10-31
AP2956A (en) 2014-08-31
AU2004257450A1 (en) 2005-01-27
ES2390224T3 (es) 2012-11-07
AP2006003506A0 (en) 2006-02-28
HRP20120721T1 (hr) 2012-10-31
PL1646425T3 (pl) 2013-01-31
US20060142216A1 (en) 2006-06-29
TNSN06006A1 (en) 2007-10-03
WO2005007241A8 (en) 2005-03-10
PT1646425E (pt) 2012-10-31
EA009602B1 (ru) 2008-02-28
GEP20094648B (en) 2009-03-25
HK1096621A1 (en) 2007-06-08
OA13188A (en) 2006-12-13
GB2403905A (en) 2005-01-19
EP2286876A1 (en) 2011-02-23
CA2532199C (en) 2012-05-15
IL173057A (en) 2013-10-31
GB0316377D0 (en) 2003-08-13
DK1646425T3 (da) 2012-09-17
NO20060676L (no) 2006-02-10
IL173057A0 (en) 2006-06-11
NO336181B1 (no) 2015-06-08
SI1646425T1 (sl) 2012-12-31
EP1646425A1 (en) 2006-04-19
BRPI0412522A (pt) 2006-09-19
CA2532199A1 (en) 2005-01-27
GB0415541D0 (en) 2004-08-11
KR101095419B1 (ko) 2011-12-16
JP4677405B2 (ja) 2011-04-27
EP1646425B1 (en) 2012-08-22
MXPA06000135A (es) 2006-04-07
CN1822880B (zh) 2012-07-11
JP2007528866A (ja) 2007-10-18
US8993546B2 (en) 2015-03-31
AU2004257450B2 (en) 2008-08-28
CN1822880A (zh) 2006-08-23
KR20060113631A (ko) 2006-11-02
CR8174A (es) 2006-10-05

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Legal Events

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MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

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MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

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MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

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MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

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