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EA200001143A1 - 2-аминопиридины, содержащие в качестве заместителей конденсированные кольца, как ингибиторы синтазы оксида азота - Google Patents

2-аминопиридины, содержащие в качестве заместителей конденсированные кольца, как ингибиторы синтазы оксида азота

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Publication number
EA200001143A1
EA200001143A1 EA200001143A EA200001143A EA200001143A1 EA 200001143 A1 EA200001143 A1 EA 200001143A1 EA 200001143 A EA200001143 A EA 200001143A EA 200001143 A EA200001143 A EA 200001143A EA 200001143 A1 EA200001143 A1 EA 200001143A1
Authority
EA
Eurasian Patent Office
Prior art keywords
condensed
deputy
nitrogen oxide
synthesis inhibitors
oxide synthesis
Prior art date
Application number
EA200001143A
Other languages
English (en)
Other versions
EA003991B1 (ru
Inventor
Джон Адамс Лоуи III
Original Assignee
Пфайзер Продактс Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Пфайзер Продактс Инк. filed Critical Пфайзер Продактс Инк.
Publication of EA200001143A1 publication Critical patent/EA200001143A1/ru
Publication of EA003991B1 publication Critical patent/EA003991B1/ru

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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
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    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
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Abstract

Настоящее изобретение относится к производным 2-аминопиридина формулы (I), где R, R, n и m являются такими, как определено в описании изобретения, к содержащим их фармацевтическим композициям и к их применению в лечении и предупреждении расстройств центральной нервной системы и других расстройств.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200001143A 1998-06-03 1999-05-07 Производные 2-аминопиридинов, способ ингибирования синтазы оксида азота, фармацевтические композиции и способы лечения EA003991B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8788198P 1998-06-03 1998-06-03
PCT/IB1999/000825 WO1999062883A1 (en) 1998-06-03 1999-05-07 2-aminopyridines containing fused ring substituents as nitric oxide synthase inhibitors

Publications (2)

Publication Number Publication Date
EA200001143A1 true EA200001143A1 (ru) 2001-06-25
EA003991B1 EA003991B1 (ru) 2003-12-25

Family

ID=22207822

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200001143A EA003991B1 (ru) 1998-06-03 1999-05-07 Производные 2-аминопиридинов, способ ингибирования синтазы оксида азота, фармацевтические композиции и способы лечения

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EP (1) EP1084109B1 (ru)
JP (1) JP3444495B2 (ru)
KR (1) KR20010052515A (ru)
CN (1) CN1303379A (ru)
AP (1) AP1208A (ru)
AR (1) AR016724A1 (ru)
AT (1) ATE287876T1 (ru)
AU (1) AU765851B2 (ru)
BG (1) BG105089A (ru)
BR (1) BR9911615A (ru)
CA (1) CA2334012C (ru)
CO (1) CO5060509A1 (ru)
DE (1) DE69923448T2 (ru)
DZ (1) DZ2807A1 (ru)
EA (1) EA003991B1 (ru)
ES (1) ES2235475T3 (ru)
GT (1) GT199900078A (ru)
HR (1) HRP20000825A2 (ru)
HU (1) HUP0102236A3 (ru)
ID (1) ID27027A (ru)
IL (1) IL139734A0 (ru)
IS (1) IS5726A (ru)
MA (1) MA24872A1 (ru)
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OA (1) OA11557A (ru)
PA (1) PA8473501A1 (ru)
PE (1) PE20000554A1 (ru)
PL (1) PL344699A1 (ru)
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WO (1) WO1999062883A1 (ru)
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Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK12022001A3 (sk) * 1999-02-25 2002-07-02 Pfizer Products Inc. 2-aminopyridíny obsahujúce ako substituenty kondenzované kruhové skupiny
GB0004153D0 (en) 2000-02-23 2000-04-12 Astrazeneca Uk Ltd Novel use
GB0004151D0 (en) 2000-02-23 2000-04-12 Astrazeneca Uk Ltd Novel use
GB0004152D0 (en) 2000-02-23 2000-04-12 Astrazeneca Uk Ltd Novel compounds
GB0004149D0 (en) * 2000-02-23 2000-04-12 Astrazeneca Uk Ltd Novel compounds
SE0102640D0 (sv) 2001-07-31 2001-07-31 Astrazeneca Ab Novel compounds
UA105182C2 (ru) 2008-07-03 2014-04-25 Ньюрексон, Інк. Бензоксазины, бензотиазины и родственные соединения, которые имеют ингибирующую nos активность

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW432073B (en) * 1995-12-28 2001-05-01 Pfizer Pyrazolopyridine compounds
HN1996000101A (es) * 1996-02-28 1997-06-26 Inc Pfizer Terapia combinada para la osteoporosis
PL329195A1 (en) * 1996-03-29 1999-03-15 Pfizer Derivatives of 6-phenylpyridol-2-amine
KR100460399B1 (ko) * 1997-02-10 2004-12-08 화이자 프로덕츠 인코포레이티드 2-아미노-6-(2-치환된-4-페녹시)-치환된-피리딘
HN1998000118A (es) * 1997-08-27 1999-02-09 Pfizer Prod Inc 2 - aminopiridinas que contienen sustituyentes de anillos condensados.

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PE20000554A1 (es) 2000-07-08
SK17912000A3 (sk) 2001-09-11
WO1999062883A1 (en) 1999-12-09
NO20006042D0 (no) 2000-11-29
EP1084109B1 (en) 2005-01-26
DE69923448T2 (de) 2005-12-29
JP3444495B2 (ja) 2003-09-08
DE69923448D1 (de) 2005-03-03
NZ508057A (en) 2003-07-25
UY25539A1 (es) 2000-12-29
MA24872A1 (fr) 1999-12-31
PL344699A1 (en) 2001-11-19
YU73200A (sh) 2003-02-28
AU765851B2 (en) 2003-10-02
AP1208A (en) 2003-09-29
EP1084109A1 (en) 2001-03-21
DZ2807A1 (fr) 2003-12-01
GT199900078A (es) 2000-11-22
IS5726A (is) 2000-11-24
JP2002516907A (ja) 2002-06-11
KR20010052515A (ko) 2001-06-25
PA8473501A1 (es) 2000-09-29
BG105089A (en) 2001-09-28
OA11557A (en) 2004-05-24
IL139734A0 (en) 2002-02-10
CO5060509A1 (es) 2001-07-30
ATE287876T1 (de) 2005-02-15
NO20006042L (no) 2001-01-31
ES2235475T3 (es) 2005-07-01
AU3438799A (en) 1999-12-20
CA2334012C (en) 2006-05-02
HUP0102236A2 (hu) 2001-11-28
EA003991B1 (ru) 2003-12-25
CA2334012A1 (en) 1999-12-09
AP9901558A0 (en) 1999-06-30
TNSN99105A1 (fr) 2005-11-10
HRP20000825A2 (en) 2001-12-31
ID27027A (id) 2001-02-22
CN1303379A (zh) 2001-07-11
ZA993699B (en) 2000-12-01
BR9911615A (pt) 2001-02-06
AR016724A1 (es) 2001-07-25
HUP0102236A3 (en) 2003-01-28

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