EA199800674A1 - Способ повторного лечения больных гепатитом с - Google Patents
Способ повторного лечения больных гепатитом сInfo
- Publication number
- EA199800674A1 EA199800674A1 EA199800674A EA199800674A EA199800674A1 EA 199800674 A1 EA199800674 A1 EA 199800674A1 EA 199800674 A EA199800674 A EA 199800674A EA 199800674 A EA199800674 A EA 199800674A EA 199800674 A1 EA199800674 A1 EA 199800674A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- patients
- hepatitis
- repeated treatment
- treatment
- interferon
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/212—IFN-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Предложены способы повторного лечения путем введения терапевтически эффективного количества и консенсусного интерферона больным, страдающим от инфекции HCV и имеющим после предварительного лечения интерфероном повышенные уровни сывороточной ALT.Международная заявка была опубликована вместе с отчетом о международном поиске.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/595,440 US5980884A (en) | 1996-02-05 | 1996-02-05 | Methods for retreatment of patients afflicted with Hepatitis C using consensus interferon |
PCT/US1997/000340 WO1997027866A1 (en) | 1996-02-05 | 1997-01-13 | Methods for retreatment of patients afflicted with hepatitis c using consensus interferon |
Publications (1)
Publication Number | Publication Date |
---|---|
EA199800674A1 true EA199800674A1 (ru) | 1999-02-25 |
Family
ID=24383236
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA199800674A EA199800674A1 (ru) | 1996-02-05 | 1997-01-13 | Способ повторного лечения больных гепатитом с |
Country Status (15)
Country | Link |
---|---|
US (1) | US5980884A (ru) |
EP (1) | EP0879059A1 (ru) |
JP (1) | JP2000504010A (ru) |
KR (1) | KR19990082084A (ru) |
CN (1) | CN1217660A (ru) |
AU (1) | AU1531897A (ru) |
BR (1) | BR9700829A (ru) |
CZ (1) | CZ231998A3 (ru) |
EA (1) | EA199800674A1 (ru) |
HU (1) | HUP9900929A3 (ru) |
IL (1) | IL125494A0 (ru) |
NO (1) | NO983410L (ru) |
SK (1) | SK101798A3 (ru) |
WO (1) | WO1997027866A1 (ru) |
ZA (1) | ZA97721B (ru) |
Families Citing this family (60)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GEP20012489B (en) * | 1996-02-28 | 2001-07-25 | Ifi Inst Farmacoterapico Italiano S P A | Use of Natural Human α-Interferon |
MY164523A (en) | 2000-05-23 | 2017-12-29 | Univ Degli Studi Cagliari | Methods and compositions for treating hepatitis c virus |
NZ547204A (en) * | 2000-05-26 | 2008-01-31 | Idenix Cayman Ltd | Methods and compositions for treating flaviviruses and pestiviruses |
US6878364B2 (en) * | 2000-12-01 | 2005-04-12 | Cornell Research Foundation, Inc. | Animal model for flaviviridae infection |
US20060035327A1 (en) * | 2001-02-28 | 2006-02-16 | Guangwen Wei | Recombinant super-compound interferon and uses thereof |
US8551469B2 (en) * | 2001-02-28 | 2013-10-08 | Superlab Far East Limited | Treatment of tumors and viral diseases with recombinant interferon alpha |
US20050079579A1 (en) * | 2001-02-28 | 2005-04-14 | Guangwen Wei | Uses of spatial configuration to modulate protein function |
CN1245215C (zh) * | 2001-02-28 | 2006-03-15 | 四川省生物工程研究中心 | 重组高效复合干扰素用作乙型肝炎表面抗原和e抗原抑制剂 |
WO2003028754A1 (en) * | 2001-09-28 | 2003-04-10 | Intermune, Inc. | Method for treating hepatitis c virus infection in treatment failure patients |
US7138376B2 (en) * | 2001-09-28 | 2006-11-21 | Idenix Pharmaceuticals, Inc. | Methods and compositions for treating hepatitis C virus using 4'-modified nucleosides |
PL369129A1 (en) * | 2001-09-28 | 2005-04-18 | Intermune, Inc. | Method for treating hepatitis c virus infection in treatment failure patients |
BR0213093A (pt) * | 2001-10-05 | 2005-03-15 | Intermune Inc | Métodos para tratamento de fibrose hepática e de infecção pelo vìrus da hepatite c |
CA2460690A1 (en) * | 2001-10-05 | 2003-04-17 | Intermune, Inc. | Method of treating hepatitis virus infection with a multiphasic interferon delivery profile |
JP2005517648A (ja) * | 2001-12-07 | 2005-06-16 | インターミューン インコーポレイテッド | 肝炎ウイルス感染症を治療するための組成物および方法 |
BR0307712A (pt) * | 2002-02-14 | 2005-05-24 | Pharmasset Ltd | Composto, composição e uso dos mesmos no tratamento de infecções por flaviviridae e proliferação celular anormal |
US20040063912A1 (en) * | 2002-03-15 | 2004-04-01 | The Brigham And Women's Hospital, Inc. | Central airway administration for systemic delivery of therapeutics |
US20030199464A1 (en) * | 2002-04-23 | 2003-10-23 | Silviu Itescu | Regeneration of endogenous myocardial tissue by induction of neovascularization |
RS113904A (en) | 2002-06-28 | 2007-02-05 | Idenix (Cayman) Limited | 2'-c-methyl-3'-o-l-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections |
JP2005533817A (ja) | 2002-06-28 | 2005-11-10 | イデニクス(ケイマン)リミテツド | フラビウィルス科ウィルス感染治療用の修飾2′および3′−ヌクレオシドプロドラッグ |
NZ537662A (en) | 2002-06-28 | 2007-10-26 | Idenix Cayman Ltd | 2'-C-methyl-3'-O-L-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections |
US7608600B2 (en) | 2002-06-28 | 2009-10-27 | Idenix Pharmaceuticals, Inc. | Modified 2′ and 3′-nucleoside prodrugs for treating Flaviviridae infections |
AU2003298658A1 (en) | 2002-11-15 | 2004-06-15 | Idenix (Cayman) Limited | 2'-branched nucleosides and flaviviridae mutation |
CA2509687C (en) | 2002-12-12 | 2012-08-14 | Idenix (Cayman) Limited | Process for the production of 2'-branched nucleosides |
WO2004078127A2 (en) * | 2003-02-28 | 2004-09-16 | Intermune, Inc. | Continuous delivery methods for treating hepatitis virus infection |
AU2003225670A1 (en) * | 2003-02-28 | 2004-09-28 | Intermune, Inc. | Interferon drug therapy for the treatment of viral diseases and liver fibrosis |
ES2586668T5 (es) | 2003-05-30 | 2024-11-12 | Gilead Pharmasset Llc | Análogos de nucleósidos fluorados modificados |
CN102294020A (zh) * | 2003-08-28 | 2011-12-28 | 辉阳科技美国公司 | 空间构象改变的干扰素及其应用 |
US7585647B2 (en) * | 2003-08-28 | 2009-09-08 | Guangwen Wei | Nucleic acid encoding recombinant interferon |
HRP20130098T1 (hr) | 2003-10-14 | 2013-02-28 | F. Hoffmann - La Roche Ag | MAKROCIKLIÄŚKE KARBOKSILNE KISELINE I ACILSULFONAMIDNI SPOJEVI KAO INHIBITORI REPLIKACIJE HCV-a |
US8906676B2 (en) | 2004-02-02 | 2014-12-09 | Ambrx, Inc. | Modified human four helical bundle polypeptides and their uses |
KR20070011451A (ko) | 2004-05-05 | 2007-01-24 | 예일 유니버시티 | 신규의 항바이러스 헬리오크산틴 유사체 |
CN101023094B (zh) | 2004-07-21 | 2011-05-18 | 法莫赛特股份有限公司 | 烷基取代的2-脱氧-2-氟代-d-呋喃核糖基嘧啶和嘌呤及其衍生物的制备 |
WO2006031725A2 (en) | 2004-09-14 | 2006-03-23 | Pharmasset, Inc. | Preparation of 2'fluoro-2'- alkyl- substituted or other optionally substituted ribofuranosyl pyrimidines and purines and their derivatives |
US20080124302A1 (en) * | 2005-03-09 | 2008-05-29 | Guangwen Wei | Uses of Recombinant Super-Compound Interferons |
SG166791A1 (en) | 2005-07-25 | 2010-12-29 | Intermune Inc | Novel macrocyclic inhibitors of hepatitis c virus replication |
KR20080056295A (ko) | 2005-10-11 | 2008-06-20 | 인터뮨, 인크. | C형 간염 바이러스 복제를 억제하기 위한 화합물 및 방법 |
ES2422290T3 (es) | 2005-12-23 | 2013-09-10 | Idenix Pharmaceuticals Inc | Procedimiento para preparar un producto intermedio sintético para la preparación de nucleósidos ramificados |
US7964580B2 (en) | 2007-03-30 | 2011-06-21 | Pharmasset, Inc. | Nucleoside phosphoramidate prodrugs |
TW200946541A (en) * | 2008-03-27 | 2009-11-16 | Idenix Pharmaceuticals Inc | Solid forms of an anti-HIV phosphoindole compound |
US8173621B2 (en) | 2008-06-11 | 2012-05-08 | Gilead Pharmasset Llc | Nucleoside cyclicphosphates |
AU2009329917B2 (en) | 2008-12-23 | 2016-03-31 | Gilead Pharmasset Llc | Nucleoside analogs |
MX2011006892A (es) | 2008-12-23 | 2011-07-20 | Pharmasset Inc | Sintesis de nucleosidos de purina. |
US8716262B2 (en) | 2008-12-23 | 2014-05-06 | Gilead Pharmasset Llc | Nucleoside phosphoramidates |
US8618076B2 (en) | 2009-05-20 | 2013-12-31 | Gilead Pharmasset Llc | Nucleoside phosphoramidates |
TWI583692B (zh) | 2009-05-20 | 2017-05-21 | 基利法瑪席特有限責任公司 | 核苷磷醯胺 |
WO2010142017A1 (en) * | 2009-06-09 | 2010-12-16 | Defyrus, Inc . | Administration of interferon for prophylaxis against or treatment of pathogenic infection |
WO2011014882A1 (en) | 2009-07-31 | 2011-02-03 | Medtronic, Inc. | CONTINUOUS SUBCUTANEOUS ADMINISTRATION OF INTERFERON-α TO HEPATITIS C INFECTED PATIENTS |
US8563530B2 (en) | 2010-03-31 | 2013-10-22 | Gilead Pharmassel LLC | Purine nucleoside phosphoramidate |
AU2011235044A1 (en) | 2010-03-31 | 2012-11-22 | Gilead Pharmasset Llc | Stereoselective synthesis of phosphorus containing actives |
WO2011159930A2 (en) | 2010-06-16 | 2011-12-22 | Medtronic, Inc. | Damping systems for stabilizing medications in drug delivery devices |
CA2818853A1 (en) | 2010-11-30 | 2012-06-07 | Gilead Pharmasset Llc | 2'-spirocyclo-nucleosides for use in therapy of hcv or dengue virus |
US8466159B2 (en) | 2011-10-21 | 2013-06-18 | Abbvie Inc. | Methods for treating HCV |
US8492386B2 (en) | 2011-10-21 | 2013-07-23 | Abbvie Inc. | Methods for treating HCV |
SE1450131A1 (sv) | 2011-10-21 | 2014-05-07 | Abbvie Inc | DAA-kombinationsbehandling (t.ex. med ABT-072 eller ABT-333)för användning vid behandling av HCV |
ES2572328B1 (es) | 2011-10-21 | 2017-08-24 | Abbvie Inc. | Combinación de al menos dos agentes antivirales de acción directa y ribavirina pero no interferón, para su uso en el tratamiento del vhc |
US8889159B2 (en) | 2011-11-29 | 2014-11-18 | Gilead Pharmasset Llc | Compositions and methods for treating hepatitis C virus |
US8809354B2 (en) | 2011-12-31 | 2014-08-19 | Sheikh Riazuddin | 3-amino-2-(4-nitrophenyl)-4-(3H)-quinazolinone or derivatives thereof for treating or preventing antiviral infections |
TW201427681A (zh) | 2013-01-07 | 2014-07-16 | Superlab Far East Ltd | 用空間構象改變的重組干擾素治療腫瘤的方法 |
NZ716840A (en) | 2013-08-27 | 2017-06-30 | Gilead Pharmasset Llc | Combination formulation of two antiviral compounds |
JP7129703B2 (ja) | 2016-04-28 | 2022-09-02 | エモリー ユニバーシティー | アルキン含有ヌクレオチド及びヌクレオシド治療組成物並びにそれらに関連した使用 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6936694B1 (en) * | 1982-05-06 | 2005-08-30 | Intermune, Inc. | Manufacture and expression of large structural genes |
US5372808A (en) * | 1990-10-17 | 1994-12-13 | Amgen Inc. | Methods and compositions for the treatment of diseases with consensus interferon while reducing side effect |
-
1996
- 1996-02-05 US US08/595,440 patent/US5980884A/en not_active Expired - Lifetime
-
1997
- 1997-01-13 CN CN97193506A patent/CN1217660A/zh active Pending
- 1997-01-13 WO PCT/US1997/000340 patent/WO1997027866A1/en not_active Application Discontinuation
- 1997-01-13 EA EA199800674A patent/EA199800674A1/ru unknown
- 1997-01-13 IL IL12549497A patent/IL125494A0/xx unknown
- 1997-01-13 JP JP9527645A patent/JP2000504010A/ja active Pending
- 1997-01-13 SK SK1017-98A patent/SK101798A3/sk unknown
- 1997-01-13 AU AU15318/97A patent/AU1531897A/en not_active Abandoned
- 1997-01-13 CZ CZ982319A patent/CZ231998A3/cs unknown
- 1997-01-13 KR KR1019980705806A patent/KR19990082084A/ko not_active Ceased
- 1997-01-13 EP EP97901413A patent/EP0879059A1/en not_active Withdrawn
- 1997-01-13 HU HU9900929A patent/HUP9900929A3/hu unknown
- 1997-01-29 ZA ZA9700721A patent/ZA97721B/xx unknown
- 1997-01-30 BR BR9700829A patent/BR9700829A/pt active Search and Examination
-
1998
- 1998-07-23 NO NO983410A patent/NO983410L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
NO983410D0 (no) | 1998-07-23 |
US5980884A (en) | 1999-11-09 |
WO1997027866A1 (en) | 1997-08-07 |
NO983410L (no) | 1998-10-05 |
HUP9900929A3 (en) | 1999-11-29 |
AU1531897A (en) | 1997-08-22 |
JP2000504010A (ja) | 2000-04-04 |
KR19990082084A (ko) | 1999-11-15 |
EP0879059A1 (en) | 1998-11-25 |
CN1217660A (zh) | 1999-05-26 |
HUP9900929A2 (hu) | 1999-07-28 |
SK101798A3 (en) | 2000-03-13 |
ZA97721B (en) | 1997-08-01 |
BR9700829A (pt) | 1998-07-07 |
IL125494A0 (en) | 1999-03-12 |
CZ231998A3 (cs) | 1999-03-17 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EA199800674A1 (ru) | Способ повторного лечения больных гепатитом с | |
MY133891A (en) | Polyethylene glycol modified interferon therapy | |
ATE295176T1 (de) | Verfahren zur unterstützung der differentialdiagnostik und behandlung von autistischen syndromen | |
KR950701350A (ko) | 부작용 감소와 동시에 인터페론을 이용한 질환의 치료방법 및 조성물(methods and compositions for the treatment of diseases with interferon while reducing side effects) | |
ATE326236T1 (de) | Hpv-e7 zur behandlung von menschlichem papillomavirus | |
DE69535758D1 (de) | Lipid-analoge zur behandlung von viralen infektionen | |
NO933171L (no) | Anvendelse av molekyler rettet mot celleoverflatereseptorer for behandling av virussykdommer | |
DE60237721D1 (de) | Kombinationstherapie mit omega-interferon zur behandlung von hepatitis c virus oder gelbfieber virus infektionen | |
ATE339211T1 (de) | L-fmau zur behandlung von hepatitis-delta-virus- infizierung | |
DE69625682D1 (de) | Verfahren zur behandlung von entzündungen und zusammensetzungen dafür | |
OA07684A (fr) | Nouveaux acides flavone-carboxylique-4, leur méthode de préparation et leur application thérapeutique. | |
ATE220332T1 (de) | Behandlung von hepatitis b mit thymosin alpha 1 und lamivudin | |
DK0752884T3 (da) | Fremgangsmåde til behandling af auto-immune sygdomme ved anvendelse af type 1 interferoner | |
FI954127A0 (fi) | Menetelmä C-hepatiitin hoitamiseksi interferonihoitoon reagoimattomissa potilaissa | |
OA08768A (fr) | Traitement du virus su SIDA par l'interféron alpha humain recombinant. | |
DK0859630T3 (da) | Kombination af termozolomid og alfa-IFN til behandling af fremskreden cancer | |
EA200300222A1 (ru) | Лечение гепатита c с помощью тимозина, интерферона и рибавирина | |
RU96121507A (ru) | Способ лечения бесплодия у мужчин | |
MY109685A (en) | Method for treating hepatitis b carriers with minimal disease | |
SE8306384D0 (sv) | Farmaceutisk komposition | |
ATE126704T1 (de) | Bcrf1-antagonisten zur behandlung von epstein- barr-virus-infektionen. | |
DE60121449D1 (de) | Behandlung von hepatitis c mit thymosin und pegyliertem interferon | |
RU95108457A (ru) | Способ лечения тяжелых форм глпс | |
RU93037848A (ru) | Способ лечения больных лепрой | |
RU98119730A (ru) | Лечение с помощью фотофереза хронического гепатита с |