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EA030186B9 - Способ проведения количественных анализов - Google Patents

Способ проведения количественных анализов

Info

Publication number
EA030186B9
EA030186B9 EA201490999A EA201490999A EA030186B9 EA 030186 B9 EA030186 B9 EA 030186B9 EA 201490999 A EA201490999 A EA 201490999A EA 201490999 A EA201490999 A EA 201490999A EA 030186 B9 EA030186 B9 EA 030186B9
Authority
EA
Eurasian Patent Office
Prior art keywords
sample
particles
inventive method
compartments
present
Prior art date
Application number
EA201490999A
Other languages
English (en)
Other versions
EA030186B1 (ru
EA201490999A1 (ru
Inventor
Пётр Гарстецкий
Павель Рафаль Дебский
Михаль Ошманец
Томаш Каминский
Адам Вархульский
Original Assignee
Кьюриосити Дайэгностикс Сп.З О.О.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PL397027A external-priority patent/PL397027A1/pl
Priority claimed from PL397026A external-priority patent/PL397026A1/pl
Priority claimed from PL397028A external-priority patent/PL397028A1/pl
Priority claimed from PL399673A external-priority patent/PL399673A1/pl
Priority claimed from PL399908A external-priority patent/PL399908A1/pl
Application filed by Кьюриосити Дайэгностикс Сп.З О.О. filed Critical Кьюриосити Дайэгностикс Сп.З О.О.
Publication of EA201490999A1 publication Critical patent/EA201490999A1/ru
Publication of EA030186B1 publication Critical patent/EA030186B1/ru
Publication of EA030186B9 publication Critical patent/EA030186B9/ru

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/06—Investigating concentration of particle suspensions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6851—Quantitative amplification
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N2015/0038—Investigating nanoparticles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Изобретение относится к способу проведения оценки концентрации частиц E(C), в котором образец заранее определенного объема разделяют на некоторое число (N) компартментов, (N) компартментов содержат или состоят из разных объемов образца (v) и/или разных коэффициентов разбавления (d) образца, по меньшей мере часть частиц, которые находятся в любом из (N) компартментов, обеспечивают измеримый сигнал, и оцениваемая концентрация частиц E(C) представляет собой функцию измеренных сигналов, а также к устройству для применения в способе по изобретению, применениям способа по изобретению, держателю образца и набору для применения в способе по изобретению.
EA201490999A 2011-11-17 2012-11-19 Способ проведения количественных анализов EA030186B9 (ru)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
PL397027A PL397027A1 (pl) 2011-11-17 2011-11-17 Sposób przeprowadzania cyfrowych oznaczen analitycznych i diagnostycznych
PL397026A PL397026A1 (pl) 2011-11-17 2011-11-17 Sposób przeprowadzania cyfrowych oznaczen analitycznych i diagnostycznych
PL397028A PL397028A1 (pl) 2011-11-17 2011-11-17 Sposób przeprowadzania cyfrowych oznaczen analitycznych i diagnostycznych
PL399673A PL399673A1 (pl) 2012-06-26 2012-06-26 Sposób przeprowadzania cyfrowych oznaczen analitycznych i diagnostycznych
PL399908A PL399908A1 (pl) 2012-07-11 2012-07-11 Sposób przeprowadzenia cyfrowych oznaczen analitycznych i diagnostycznych
PCT/EP2012/004792 WO2013072069A1 (en) 2011-11-17 2012-11-19 Method for performing quantitation assays

Publications (3)

Publication Number Publication Date
EA201490999A1 EA201490999A1 (ru) 2014-11-28
EA030186B1 EA030186B1 (ru) 2018-07-31
EA030186B9 true EA030186B9 (ru) 2018-09-28

Family

ID=47429726

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201490999A EA030186B9 (ru) 2011-11-17 2012-11-19 Способ проведения количественных анализов

Country Status (10)

Country Link
US (2) US20140278143A1 (ru)
EP (1) EP2780470B1 (ru)
JP (1) JP6055838B2 (ru)
KR (1) KR101839180B1 (ru)
CN (1) CN104053784B (ru)
BR (1) BR112014011818A2 (ru)
EA (1) EA030186B9 (ru)
HK (1) HK1202311A1 (ru)
PL (1) PL2780470T3 (ru)
WO (1) WO2013072069A1 (ru)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
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CA2956645A1 (en) 2003-07-12 2005-03-31 David A. Goldberg Sensitive and rapid biodetection
US20120077206A1 (en) 2003-07-12 2012-03-29 Accelr8 Technology Corporation Rapid Microbial Detection and Antimicrobial Susceptibility Testing
US10254204B2 (en) 2011-03-07 2019-04-09 Accelerate Diagnostics, Inc. Membrane-assisted purification
WO2012122314A2 (en) 2011-03-07 2012-09-13 Accelr8 Technology Corporation Rapid cell purification systems
WO2014000834A1 (en) 2012-06-26 2014-01-03 Curiosity Diagnostics Sp. Z O.O. Method for performing quantitation assays
US9677109B2 (en) 2013-03-15 2017-06-13 Accelerate Diagnostics, Inc. Rapid determination of microbial growth and antimicrobial susceptibility
US10612080B2 (en) * 2014-09-22 2020-04-07 Roche Molecular Systems, Inc. Digital PCR for non-invasive prenatal testing
US10253355B2 (en) 2015-03-30 2019-04-09 Accelerate Diagnostics, Inc. Instrument and system for rapid microorganism identification and antimicrobial agent susceptibility testing
AU2016243656A1 (en) 2015-03-30 2017-11-09 Accelerate Diagnostics, Inc. Instrument and system for rapid microorganism identification and antimicrobial agent susceptibility testing
US11168347B2 (en) 2016-09-23 2021-11-09 California Institute Of Technology Digital quantification of DNA replication and/or chromosome segregation based determination of antimicrobial susceptibility
US9976997B2 (en) * 2016-10-17 2018-05-22 Shimadzu Corporation Data processing device for quantitation
JP2019013218A (ja) * 2017-07-06 2019-01-31 キヤノン株式会社 分析システム、分析方法、プログラム、および記憶媒体
WO2019009297A1 (ja) * 2017-07-06 2019-01-10 キヤノン株式会社 分析システム、分析方法、プログラム、および記憶媒体
EP3695009A4 (en) 2017-10-11 2021-08-11 California Institute of Technology Antibiotic susceptibility of microorganisms and related compositions, methods and systems
CA3188454A1 (en) 2018-01-24 2019-08-01 Sniper (Suzhou) Life Technology Co., Ltd Motion controlling mechanism, liquid discharging nozzle, microdroplet generating device and method, liquid driving mechanism and method, microdroplet generating method, and surface processing method of liquid discharging nozzle
US11946100B2 (en) 2018-01-24 2024-04-02 Sniper (Suzhou) Life Technology Co., Ltd. Microdroplet container and method for manufacturing the same, method for spreading microdroplets, microdroplet-generating kit, temperature-controlling device, oil phase composition for microdroplet generating and method for treating the same
JP7094524B2 (ja) * 2018-01-24 2022-07-04 思納福（北京）医療科技有限公司 デジタルｐｃｒ検出器、デジタルｐｃｒ定量検出方法、異なる体積のデジタルｐｃｒの定量解析方法、デジタルｐｃｒ検出方法、核酸検出微小球、核酸検出微小球製造方法、核酸検出微小球試薬キット及びハイスループット核酸検出方法
US20210214779A1 (en) * 2018-09-19 2021-07-15 Inflammatix, Inc. Assessing host rna using isothermal amplification and relative abundance
US11305284B2 (en) 2018-11-26 2022-04-19 Tokitae, LLC Determining a bulk concentration of a target in a sample using a digital assay with compartments having nonuniform volumes

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003091410A2 (en) * 2002-04-26 2003-11-06 Children's Medical Center Corporation Method of fingerprinting tissue samples
US8676383B2 (en) * 2002-12-23 2014-03-18 Applied Biosystems, Llc Device for carrying out chemical or biological reactions
WO2006108559A2 (de) * 2005-04-09 2006-10-19 Boehringer Ingelheim Microparts Gmbh Vorrichtung und verfahren zur untersuchung einer probenflüssigkeit
US20100124766A1 (en) * 2008-11-14 2010-05-20 Life Technologies Corporation Apparatus and Method for Segmented Thermal Cycler
EP2627781B1 (en) 2010-10-15 2017-02-22 Olink Bioscience AB Dynamic range methods
WO2012100198A2 (en) 2011-01-20 2012-07-26 University Of Washington Through Its Center For Commercialization Methods and systems for performing digital measurements
EP3859011A1 (en) 2011-02-11 2021-08-04 Bio-Rad Laboratories, Inc. Methods for forming mixed droplets
WO2014000834A1 (en) * 2012-06-26 2014-01-03 Curiosity Diagnostics Sp. Z O.O. Method for performing quantitation assays

Also Published As

Publication number Publication date
PL2780470T3 (pl) 2017-09-29
KR20140114343A (ko) 2014-09-26
JP6055838B2 (ja) 2016-12-27
US20170322136A1 (en) 2017-11-09
KR101839180B1 (ko) 2018-03-15
CN104053784A (zh) 2014-09-17
WO2013072069A1 (en) 2013-05-23
EP2780470A1 (en) 2014-09-24
BR112014011818A2 (pt) 2017-05-02
EA030186B1 (ru) 2018-07-31
JP2015504305A (ja) 2015-02-12
EA201490999A1 (ru) 2014-11-28
US20140278143A1 (en) 2014-09-18
CN104053784B (zh) 2017-04-19
EP2780470B1 (en) 2016-09-14
HK1202311A1 (en) 2015-09-25

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Legal Events

Date Code Title Description
TH4A Publication of the corrected specification to eurasian patent
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG TJ TM