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DK659089A - Mevalonolactoner af pyrazolopyridintypen - Google Patents

Mevalonolactoner af pyrazolopyridintypen Download PDF

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Publication number
DK659089A
DK659089A DK659089A DK659089A DK659089A DK 659089 A DK659089 A DK 659089A DK 659089 A DK659089 A DK 659089A DK 659089 A DK659089 A DK 659089A DK 659089 A DK659089 A DK 659089A
Authority
DK
Denmark
Prior art keywords
mevalonolactons
pyrazolopyridine
type
pyrazolopyridine type
chem
Prior art date
Application number
DK659089A
Other languages
English (en)
Other versions
DK659089D0 (da
Inventor
Yoshihiro Fujikawa
Mikio Suzuki
Hiroshi Iwasaki
Mitsuaki Sakashita
Masaki Kitahara
Original Assignee
Nissan Chemical Ind Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nissan Chemical Ind Ltd filed Critical Nissan Chemical Ind Ltd
Publication of DK659089A publication Critical patent/DK659089A/da
Publication of DK659089D0 publication Critical patent/DK659089D0/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Enzymes And Modification Thereof (AREA)
DK659089A 1988-04-26 1989-12-22 Mevalonolactoner af pyrazolopyridintypen DK659089D0 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP10309088 1988-04-26
JP27143988 1988-10-27
JP1684689 1989-01-26
PCT/JP1989/000423 WO1989010365A1 (en) 1988-04-26 1989-04-19 Pyrazolopyridine type mevalonolactones

Publications (2)

Publication Number Publication Date
DK659089A true DK659089A (da) 1989-12-22
DK659089D0 DK659089D0 (da) 1989-12-22

Family

ID=27281590

Family Applications (1)

Application Number Title Priority Date Filing Date
DK659089A DK659089D0 (da) 1988-04-26 1989-12-22 Mevalonolactoner af pyrazolopyridintypen

Country Status (10)

Country Link
EP (1) EP0339358B1 (da)
JP (1) JP2890448B2 (da)
KR (1) KR970009222B1 (da)
AT (1) ATE108450T1 (da)
DE (1) DE68916685T2 (da)
DK (1) DK659089D0 (da)
FI (1) FI90870C (da)
HU (1) HU203888B (da)
NO (1) NO173501C (da)
WO (1) WO1989010365A1 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3130342B2 (ja) * 1991-10-04 2001-01-31 日産化学工業株式会社 動脈硬化性血管内膜肥厚抑制薬
US6949648B2 (en) 2000-03-27 2005-09-27 Takeda Pharmaceutical Company Limited Condensed pyrazole derivatives, process for producing the same and use thereof
WO2009000832A2 (en) * 2007-06-25 2008-12-31 Boehringer Ingelheim International Gmbh Chemical compounds
AU2008331733A1 (en) 2007-11-02 2009-06-11 Vertex Pharmaceuticals Incorporated [1H- pyrazolo [3, 4-b] pyridine-4-yl] -phenyle or -pyridin-2-yle derivatives as protein kinase C-theta
GEP201706620B (en) 2012-06-29 2017-02-10 Pfizer NOVEL 4-(SUBSTITUTED-AMINO)-7H-PYRROLO[2,3-d]PYRIMIDINES AS LRRK2 INHIBITORS
WO2015092592A1 (en) 2013-12-17 2015-06-25 Pfizer Inc. Novel 3,4-disubstituted-1h-pyrrolo[2,3-b]pyridines and 4,5-disubstituted-7h-pyrrolo[2,3-c]pyridazines as lrrk2 inhibitors
EP3350178B1 (en) 2015-09-14 2021-10-20 Pfizer Inc. Novel imidazo [4,5-c]quinoline and imidazo [4,5-c][1,5]naphthyridine derivatives as lrrk2 inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU204253B (en) * 1982-11-22 1991-12-30 Sandoz Ag Process for producing mevalonolactone analogues and derivatives and pharmaceutical compositions containing them
DE3582674D1 (de) * 1984-06-22 1991-05-29 Sandoz Ag Pyrazolanaloge von mevalonolakton und abkoemmlinge davon, verfahren zu deren herstellung und deren verwendung.
US4761419A (en) * 1987-12-07 1988-08-02 Warner-Lambert Company 6-(((substituted)quinolinyl)ethyl)-and ethenyl)tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis
US4822799A (en) * 1988-01-27 1989-04-18 Sandoz Pharm. Corp. Pyrazolopyridine analogs of mevalonolactone and derivatives thereof useful for inhibiting cholesterol biosynthesis in mammals

Also Published As

Publication number Publication date
JP2890448B2 (ja) 1999-05-17
EP0339358A1 (en) 1989-11-02
NO173501B (no) 1993-09-13
JPH02275878A (ja) 1990-11-09
EP0339358B1 (en) 1994-07-13
ATE108450T1 (de) 1994-07-15
KR900700480A (ko) 1990-08-13
KR970009222B1 (ko) 1997-06-09
HU892751D0 (en) 1990-03-28
NO895165L (no) 1989-12-21
WO1989010365A1 (en) 1989-11-02
DK659089D0 (da) 1989-12-22
DE68916685D1 (de) 1994-08-18
FI896251A0 (fi) 1989-12-22
NO173501C (no) 1993-12-22
FI90870B (fi) 1993-12-31
FI90870C (fi) 1994-04-11
HU203888B (en) 1991-10-28
DE68916685T2 (de) 1995-02-09
NO895165D0 (no) 1989-12-21

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