DK621589A - Mellemprodukter til syntese af hidtil ukendte 4-cyanopyridaziner - Google Patents
Mellemprodukter til syntese af hidtil ukendte 4-cyanopyridaziner Download PDFInfo
- Publication number
- DK621589A DK621589A DK621589A DK621589A DK621589A DK 621589 A DK621589 A DK 621589A DK 621589 A DK621589 A DK 621589A DK 621589 A DK621589 A DK 621589A DK 621589 A DK621589 A DK 621589A
- Authority
- DK
- Denmark
- Prior art keywords
- unknown
- cyanopyridazines
- intermediates
- synthesis
- unknown unknown
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8301366A FR2540115B1 (fr) | 1983-01-28 | 1983-01-28 | Derive de la pyridazine ayant une action psychotrope, son mode de preparation et les medicaments en contenant |
| FR8301366 | 1983-01-28 | ||
| FR8318433A FR2555178B1 (fr) | 1983-11-18 | 1983-11-18 | Derives cyanes de la pyridazine ayant une action psychotrope, leur mode de preparation et les medicaments en contenant |
| FR8318433 | 1983-11-18 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| DK621589D0 DK621589D0 (da) | 1989-12-08 |
| DK621589A true DK621589A (da) | 1989-12-08 |
| DK162218B DK162218B (da) | 1991-09-30 |
| DK162218C DK162218C (da) | 1992-03-02 |
Family
ID=26223263
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK025984A DK159969C (da) | 1983-01-28 | 1984-01-20 | Pyridazinderivater, der har psykotropisk virkning, og laegemidler indeholdende dem |
| DK621689A DK162219C (da) | 1983-01-28 | 1989-12-08 | 3-chlor-4-cyanopyridaziner til syntese af hidtil ukendte 4-cyanopyridaziner |
| DK621589A DK162218C (da) | 1983-01-28 | 1989-12-08 | 3-oxo-4-carboxamidopyridaziner til syntese af hidtil ukendte 4-cyano-pyridaziner |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK025984A DK159969C (da) | 1983-01-28 | 1984-01-20 | Pyridazinderivater, der har psykotropisk virkning, og laegemidler indeholdende dem |
| DK621689A DK162219C (da) | 1983-01-28 | 1989-12-08 | 3-chlor-4-cyanopyridaziner til syntese af hidtil ukendte 4-cyanopyridaziner |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US4565814A (da) |
| EP (1) | EP0116494B1 (da) |
| KR (1) | KR910000639B1 (da) |
| AU (1) | AU566352B2 (da) |
| CA (1) | CA1218655A (da) |
| CS (1) | CS274405B2 (da) |
| DD (1) | DD215542A5 (da) |
| DE (1) | DE3469026D1 (da) |
| DK (3) | DK159969C (da) |
| ES (1) | ES529108A0 (da) |
| FI (1) | FI77453C (da) |
| GR (1) | GR81682B (da) |
| HU (1) | HU192975B (da) |
| IE (1) | IE56750B1 (da) |
| IL (1) | IL70755A (da) |
| MA (1) | MA20019A1 (da) |
| NO (1) | NO840329L (da) |
| NZ (1) | NZ206957A (da) |
| OA (1) | OA07645A (da) |
| PH (1) | PH21476A (da) |
| PL (1) | PL143994B1 (da) |
| PT (1) | PT77994B (da) |
| SG (1) | SG9389G (da) |
| SU (1) | SU1274623A3 (da) |
| YU (1) | YU14184A (da) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2540113A1 (fr) * | 1983-01-27 | 1984-08-03 | Sanofi Sa | Acides derives de la pyridazine actifs sur le systeme nerveux central |
| EP0208431B1 (en) * | 1985-06-14 | 1990-07-11 | Eli Lilly And Company | Fungicidal pyridazines |
| US5106973A (en) * | 1987-11-23 | 1992-04-21 | Janssen Pharmaceutica N.V. | Pyridzainamine derivatives |
| MXPA01001843A (es) * | 1998-08-20 | 2002-04-08 | Toyama Chemical Co Ltd | Derivados de carboxamida heterociclica con nitrogeno o sales derivados de los mismos y agentes antivirales que comprenden los mismos. |
| DK1144388T3 (da) | 1999-01-22 | 2010-05-25 | Elan Pharm Inc | Acyl-derivater, som behandler VLA-4-relaterede lidelser |
| TW200307671A (en) | 2002-05-24 | 2003-12-16 | Elan Pharm Inc | Heteroaryl compounds which inhibit leukocyte adhesion mediated by α 4 integrins |
| TWI281470B (en) | 2002-05-24 | 2007-05-21 | Elan Pharm Inc | Heterocyclic compounds which inhibit leukocyte adhesion mediated by alpha4 integrins |
| CN1984904A (zh) * | 2004-05-08 | 2007-06-20 | 神经能质公司 | 3－芳基－5,6－二取代哒嗪 |
| EP1741709A1 (en) * | 2005-06-28 | 2007-01-10 | Sanofi-Aventis Deutschland GmbH | Heteroaryl-substituted amides comprising a saturated linker group, and their use as pharmaceuticals |
| CA2624450C (en) | 2005-09-29 | 2014-02-04 | Elan Pharmaceuticals, Inc. | Pyrimidinyl amide compounds which inhibit leukocyte adhesion mediated by vla-4 |
| BRPI0616643A2 (pt) | 2005-09-29 | 2011-06-28 | Elan Pharm Inc | compostos de carbamato que inibem a adesão leucocitária mediada por vla-4 |
| EA017110B1 (ru) | 2006-02-27 | 2012-09-28 | Элан Фамэсьютикэлс, Инк. | ПИРИМИДИНИЛСУЛЬФОНАМИДНЫЕ СОЕДИНЕНИЯ (ВАРИАНТЫ), СПОСОБ ПОЛУЧЕНИЯ ПИРИМИДИНИЛСУЛЬФОНАМИДНЫХ СОЕДИНЕНИЙ (ВАРИАНТЫ), ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, СПОСОБ ЛЕЧЕНИЯ ЗАБОЛЕВАНИЯ, ОПОСРЕДОВАННОГО ИНТЕГРИНОМ α4, СПОСОБ СНИЖЕНИЯ И/ИЛИ ПРЕДУПРЕЖДЕНИЯ ВОСПАЛИТЕЛЬНОГО КОМПОНЕНТА ЗАБОЛЕВАНИЯ ИЛИ АУТОИММУННОГО ОТВЕТА |
| WO2010126914A1 (en) | 2009-04-27 | 2010-11-04 | Elan Pharmaceuticals, Inc. | Pyridinone antagonists of alpha-4 integrins |
| EP2560488B1 (en) | 2010-04-23 | 2015-10-28 | Cytokinetics, Inc. | Certain amino-pyridines and amino-triazines, compositions thereof, and methods for their use |
| AR081626A1 (es) | 2010-04-23 | 2012-10-10 | Cytokinetics Inc | Compuestos amino-piridazinicos, composiciones farmaceuticas que los contienen y uso de los mismos para tratar trastornos musculares cardiacos y esqueleticos |
| AR081331A1 (es) | 2010-04-23 | 2012-08-08 | Cytokinetics Inc | Amino- pirimidinas composiciones de las mismas y metodos para el uso de los mismos |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1345880A (en) * | 1971-06-18 | 1974-02-06 | Cepbepe | Pyridazine derivatives |
| FR2510998B1 (fr) * | 1981-08-07 | 1986-01-10 | Sanofi Sa | Nouveaux derives amines de la pyridazine, leur procede de preparation et les medicaments, a action desinhibitrice, qui en comportent |
| FR2510997A1 (fr) * | 1981-08-10 | 1983-02-11 | Sanofi Sa | Nouveaux derives de la methyl-4 phenyl-6 pyridazine, procede pour leur preparation et medicaments actifs sur le systeme nerveux central en contenant |
| FR2539739B1 (fr) * | 1983-01-24 | 1985-11-22 | Sanofi Sa | Nouveaux derives de la naphtyl pyridazine actifs sur le systeme nerveux central, procede de preparation de ces derives et medicaments en contenant |
-
1984
- 1984-01-18 CA CA000445482A patent/CA1218655A/en not_active Expired
- 1984-01-18 US US06/571,696 patent/US4565814A/en not_active Expired - Fee Related
- 1984-01-20 PH PH30136A patent/PH21476A/en unknown
- 1984-01-20 DK DK025984A patent/DK159969C/da not_active IP Right Cessation
- 1984-01-23 GR GR73586A patent/GR81682B/el unknown
- 1984-01-23 PT PT77994A patent/PT77994B/pt not_active IP Right Cessation
- 1984-01-23 IL IL70755A patent/IL70755A/xx unknown
- 1984-01-23 IE IE148/84A patent/IE56750B1/en not_active IP Right Cessation
- 1984-01-24 AU AU23728/84A patent/AU566352B2/en not_active Ceased
- 1984-01-24 ES ES529108A patent/ES529108A0/es active Granted
- 1984-01-25 EP EP84400157A patent/EP0116494B1/fr not_active Expired
- 1984-01-25 DE DE8484400157T patent/DE3469026D1/de not_active Expired
- 1984-01-26 MA MA20240A patent/MA20019A1/fr unknown
- 1984-01-26 OA OA58217A patent/OA07645A/xx unknown
- 1984-01-27 SU SU843697653A patent/SU1274623A3/ru active
- 1984-01-27 PL PL1984245932A patent/PL143994B1/pl unknown
- 1984-01-27 HU HU84378A patent/HU192975B/hu not_active IP Right Cessation
- 1984-01-27 FI FI840349A patent/FI77453C/fi not_active IP Right Cessation
- 1984-01-27 CS CS61484A patent/CS274405B2/cs unknown
- 1984-01-27 YU YU00141/84A patent/YU14184A/xx unknown
- 1984-01-27 DD DD84259679A patent/DD215542A5/de not_active IP Right Cessation
- 1984-01-27 NZ NZ206957A patent/NZ206957A/en unknown
- 1984-01-27 NO NO840329A patent/NO840329L/no unknown
- 1984-01-28 KR KR1019840000387A patent/KR910000639B1/ko active IP Right Grant
-
1985
- 1985-05-20 US US06/735,580 patent/US4631280A/en not_active Expired - Fee Related
-
1989
- 1989-02-14 SG SG93/89A patent/SG9389G/en unknown
- 1989-12-08 DK DK621689A patent/DK162219C/da not_active IP Right Cessation
- 1989-12-08 DK DK621589A patent/DK162218C/da not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |