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DK592189A - Nitroimidazoler, fremgangsmaade til fremstilling deraf samt farmaceutiske praeparater indeholdende samme - Google Patents

Nitroimidazoler, fremgangsmaade til fremstilling deraf samt farmaceutiske praeparater indeholdende samme

Info

Publication number
DK592189A
DK592189A DK592189A DK592189A DK592189A DK 592189 A DK592189 A DK 592189A DK 592189 A DK592189 A DK 592189A DK 592189 A DK592189 A DK 592189A DK 592189 A DK592189 A DK 592189A
Authority
DK
Denmark
Prior art keywords
nitroimidazoles
procedures
preparing
same
pharmaceutical preparations
Prior art date
Application number
DK592189A
Other languages
English (en)
Other versions
DK592189D0 (da
Inventor
Mark James Suto
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of DK592189D0 publication Critical patent/DK592189D0/da
Publication of DK592189A publication Critical patent/DK592189A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/91—Nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK592189A 1988-11-25 1989-11-24 Nitroimidazoler, fremgangsmaade til fremstilling deraf samt farmaceutiske praeparater indeholdende samme DK592189A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/274,209 US4954515A (en) 1988-11-25 1988-11-25 Haloalkylaminomethyl-2-nitro-1H-imidazoles

Publications (2)

Publication Number Publication Date
DK592189D0 DK592189D0 (da) 1989-11-24
DK592189A true DK592189A (da) 1990-05-26

Family

ID=23047251

Family Applications (1)

Application Number Title Priority Date Filing Date
DK592189A DK592189A (da) 1988-11-25 1989-11-24 Nitroimidazoler, fremgangsmaade til fremstilling deraf samt farmaceutiske praeparater indeholdende samme

Country Status (6)

Country Link
US (1) US4954515A (da)
EP (1) EP0375951A1 (da)
JP (1) JPH02193980A (da)
CA (1) CA2003868A1 (da)
DK (1) DK592189A (da)
PT (1) PT92391B (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8728418D0 (en) * 1987-12-04 1988-01-13 Jenkins T C Nitro-substituted aromatic/hetero-aromatic compounds for use in cancer treatment
US5294715A (en) * 1991-02-01 1994-03-15 University Of Pittsburgh Acridine-intercalator based hypoxia selective cytotoxins
MX9304399A (es) * 1992-07-31 1994-02-28 Warner Lambert Co Proceso novedoso para preparar [[2-bromoetil)-amino]metil]-2-nitro-1h-imidazol-1-etanol quiral y compuestos relacionados.
GB9404400D0 (en) * 1994-03-07 1994-04-20 Wood Pauline J Potentiation of bioreductive agents
US6060604A (en) * 1995-03-31 2000-05-09 Florida State University Pharmaceutical compounds comprising polyamines substituted with electron-affinic groups
US5965621A (en) * 1995-08-17 1999-10-12 Allergan Methods and compositions for reducing or maintaining body weight in a mammal
US6331286B1 (en) 1998-12-21 2001-12-18 Photogen, Inc. Methods for high energy phototherapeutics
US8974363B2 (en) * 1997-12-11 2015-03-10 Provectus Pharmatech, Inc. Topical medicaments and methods for photodynamic treatment of disease
US8557298B2 (en) * 1998-08-06 2013-10-15 Provectus Pharmatech, Inc. Medicaments for chemotherapeutic treatment of disease
US20090117199A1 (en) * 1998-08-06 2009-05-07 Scott Timothy C Method of treatment of cancer
US8470296B2 (en) * 1998-12-21 2013-06-25 Provectus Pharmatech, Inc. Intracorporeal medicaments for high energy phototherapeutic treatment of disease
US20020001567A1 (en) * 1998-12-21 2002-01-03 Photogen, Inc. Intracorporeal medicaments for high energy phototherapeutic treatment of disease
US7384623B1 (en) 1998-12-21 2008-06-10 Provectus Pharmatech, Inc. High energy phototherapeutic agents
US7875602B2 (en) * 2005-10-21 2011-01-25 Sutter West Bay Hospitals Camptothecin derivatives as chemoradiosensitizing agents

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1526451A (en) * 1976-01-27 1978-09-27 Lepetit Spa Alpha,alpha,1-trimethyl-2-nitroimidazole-5-methanol derivatives
IE47132B1 (en) * 1977-08-19 1983-12-28 Roche Products Ltd Novel nitroimidazoles and pharmaceutical preparations containing these as well as their manufacture
US4282232A (en) * 1979-04-26 1981-08-04 Research Corporation Nitroimidazole radiosensitizers for hypoxic tumor cells and compositions thereof
US4371540A (en) * 1979-09-14 1983-02-01 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Nitroimidazoles of low toxicity and high activity as radiosensitizers of hypoxic tumor cells
US4462992A (en) * 1982-02-08 1984-07-31 Research Corporation Nitroimidazole radiosensitizers for hypoxic tumor cells and compositions thereof
GB2123816B (en) * 1982-05-27 1986-03-19 Nat Res Dev Nitrolmidazole derivatives
DE3872949D1 (de) * 1987-06-05 1992-08-27 Basf Ag Verfahren zur herstellung von 4-nitro-5-imidazolylethern und -thioethern.
US4797397A (en) * 1987-07-31 1989-01-10 Warner-Lambert Company 2-nitroimidazole derivatives useful as radiosensitizers for hypoxic tumor cells
ES2080726T3 (es) * 1987-12-04 1996-02-16 British Tech Group Compuestos aromaticos o heteroaromaticos nitrosustituidos para su utilizacion en el tratamiento del cancer.

Also Published As

Publication number Publication date
EP0375951A1 (en) 1990-07-04
DK592189D0 (da) 1989-11-24
JPH02193980A (ja) 1990-07-31
US4954515A (en) 1990-09-04
PT92391B (pt) 1995-08-09
CA2003868A1 (en) 1990-05-25
PT92391A (pt) 1990-05-31

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Legal Events

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