DK584188D0 - Aminomethyl-oxooxazolidinyl-ethenylbenzenderivater, deres fremstilling og anvendelse i laegemidler til bekaempelse af infektioner - Google Patents

Aminomethyl-oxooxazolidinyl-ethenylbenzenderivater, deres fremstilling og anvendelse i laegemidler til bekaempelse af infektioner

Info

Publication number: DK584188D0
Authority: DK; Denmark
Prior art keywords: oxooxazolidinyl; aminomethyl; combect; infections; preparation
Prior art date: 1987-10-21

Application number

DK584188A

Other languages

English (en)

Other versions

DK584188A (da

Inventor

David Ross Brittelli

Peter Fraklin Corless

Walter Adelman Gregory

Chung-Ho Park

Original Assignee

Du Pont

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-10-21

Filing date

1988-10-20

Publication date

1988-10-20

1988-10-20 Application filed by Du Pont filed Critical Du Pont

1988-10-20 Publication of DK584188D0 publication Critical patent/DK584188D0/da

1989-04-22 Publication of DK584188A publication Critical patent/DK584188A/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

DK584188A 1987-10-21 1988-10-20 Aminomethyl-oxooxazolidinyl-ethenylbenzenderivater, deres fremstilling og anvendelse i laegemidler til bekaempelse af infektioner DK584188A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US11083787A	1987-10-21	1987-10-21

Publications (2)

Publication Number	Publication Date
DK584188D0 true DK584188D0 (da)	1988-10-20
DK584188A DK584188A (da)	1989-04-22

Family

ID=22335197

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK584188A DK584188A (da)	1987-10-21	1988-10-20	Aminomethyl-oxooxazolidinyl-ethenylbenzenderivater, deres fremstilling og anvendelse i laegemidler til bekaempelse af infektioner

Country Status (18)

Country	Link
EP (1)	EP0316594B1 (da)
JP (1)	JPH01135777A (da)
KR (1)	KR890006603A (da)
AT (1)	ATE95176T1 (da)
AU (1)	AU617697B2 (da)
CA (1)	CA1317594C (da)
DE (1)	DE3884563T2 (da)
DK (1)	DK584188A (da)
ES (1)	ES2059467T3 (da)
FI (1)	FI884849A (da)
HU (1)	HU201915B (da)
IL (1)	IL88107A (da)
MY (1)	MY103433A (da)
NO (1)	NO884676L (da)
NZ (1)	NZ226631A (da)
PT (1)	PT88811B (da)
RU (1)	RU1801109C (da)
ZA (1)	ZA887853B (da)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
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US5036093A (en) *	1987-10-09	1991-07-30	Du Pont Merck Pharmaceutical	Aminomethyl oxooxazolidinyl azacycloalkylbenzene derivatives useful as antibacterial agents
US5032605A (en) *	1987-10-09	1991-07-16	Du Pont Merck Pharmaceutical Company	Aminomethyl oxooxazolidinyl oxa or thia cycloalkylbenzene derivatives useful as antibacterial agents
US4948801A (en) *	1988-07-29	1990-08-14	E. I. Du Pont De Nemours And Company	Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
US5225565A (en) *	1988-09-15	1993-07-06	The Upjohn Company	Antibacterial 3-(fused-ring substituted)phenyl-5β-amidomethyloxazolidin-2-ones
US5231188A (en) *	1989-11-17	1993-07-27	The Upjohn Company	Tricyclic [6.5.51]-fused oxazolidinone antibacterial agents
AU667198B2 (en) *	1991-11-01	1996-03-14	Pharmacia & Upjohn Company	Substituted aryl- and heteroarylphenyloxazolidinones useful as antibacterial agents
SK283420B6 (sk) *	1992-05-08	2003-07-01	Pharmacia & Upjohn Company	Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny
TW299332B (da) *	1992-12-08	1997-03-01	Upjohn Co
KR100276382B1 (ko) *	1992-12-08	2000-12-15	로렌스 티. 마이젠헬더	트로폰-치환된 페닐옥사졸리디논 항균제
US5688792A (en) *	1994-08-16	1997-11-18	Pharmacia & Upjohn Company	Substituted oxazine and thiazine oxazolidinone antimicrobials
CN1046276C (zh) *	1993-11-22	1999-11-10	法玛西雅厄普约翰美国公司	取代羟基乙酰基哌嗪苯基唑烷酮酯及其用途
PL183512B1 (pl) *	1994-10-26	2002-06-28	Upjohn Co	Przeciwbakteryjne fenylooksazolidynony
RU2128660C1 (ru) *	1994-11-15	1999-04-10	Фармация Энд Апджон Компани	Бициклические оксазин- или тиазин-оксазолидиноны или их фармацевтически приемлемые соли и способы лечения микробных инфекций
CA2208603A1 (en) *	1995-02-03	1996-08-08	The Upjohn Company	Hetero-aromatic ring substituted phenyloxazolidinone antimicrobials
ATE204874T1 (de) *	1995-05-11	2001-09-15	Upjohn Co	Spirocyclische und bicyclische diazinyl- und carbazinyloxazolidinone
US5883093A (en) *	1995-09-12	1999-03-16	Pharmacia & Upjohn Company	Phenyloxazolidinone antimicrobials
GB9702213D0 (en)	1996-02-24	1997-03-26	Zeneca Ltd	Chemical compounds
GB9609919D0 (en) *	1996-05-11	1996-07-17	Zeneca Ltd	Chemical compounds
US5929117A (en)	1996-08-12	1999-07-27	Celgene Corporation	Immunotherapeutic agents
GB9717804D0 (en)	1997-08-22	1997-10-29	Zeneca Ltd	Chemical compounds
GB9717807D0 (en) *	1997-08-22	1997-10-29	Zeneca Ltd	Chemical compounds
KR20010031953A (ko) *	1997-11-12	2001-04-16	로렌스 티. 마이젠헬더	옥사졸리디논 유도체 및 제약 조성물
GB9725244D0 (en)	1997-11-29	1998-01-28	Zeneca Ltd	Chemical compounds
US6562844B2 (en)	1998-01-23	2003-05-13	Pharmacia & Upjohn Company	Oxazolidinone combinatorial libraries, compositions and methods of preparation
US7002020B1 (en)	1998-01-23	2006-02-21	Pharmacia & Upjohn Company	Oxazolidinone combinatorial libraries, compositions and methods of preparation
JP2002501059A (ja)	1998-01-23	2002-01-15	ファルマシア・アンド・アップジョン・カンパニー	オキサゾリジノンの組合せライブラリー、組成物および調製方法
BR0012742A (pt) *	1999-07-28	2002-06-11	Upjohn Co	Oxazolidinonas e seus usos como antibiótico
DE19962924A1 (de)	1999-12-24	2001-07-05	Bayer Ag	Substituierte Oxazolidinone und ihre Verwendung
WO2002018354A1 (en) *	2000-08-31	2002-03-07	Abbott Laboratories	Oxazolidinones and their use as antibacterial agents
WO2002020515A1 (en) *	2000-09-08	2002-03-14	Abbott Laboratories	Oxazolidinone antibacterial agents
DE10129725A1 (de)	2001-06-20	2003-01-02	Bayer Ag	Kombinationstherapie substituierter Oxazolidinone
US7125568B2 (en)	2001-08-23	2006-10-24	Sung Michael T	Lipophilic drug compositions
DE10300111A1 (de)	2003-01-07	2004-07-15	Bayer Healthcare Ag	Verfahren zur Herstellung von 5-Chlor-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophencarboxamid
US7470723B2 (en)	2003-03-05	2008-12-30	Celgene Corporation	Diphenylethylene compounds and uses thereof
EP1603864A4 (en)	2003-03-05	2007-04-11	Celgene Corp	DIPHENYLETHYLENE COMPOUNDS AND THEIR USE
DE10355461A1 (de)	2003-11-27	2005-06-23	Bayer Healthcare Ag	Verfahren zur Herstellung einer festen, oral applizierbaren pharmazeutischen Zusammensetzung
EP1794139A2 (en)	2004-09-03	2007-06-13	Celgene Corporation	Substituted heterocyclic compounds and uses thereof
EP1685841A1 (en)	2005-01-31	2006-08-02	Bayer Health Care Aktiengesellschaft	Prevention and treatment of thromboembolic disorders
DE102005045518A1 (de)	2005-09-23	2007-03-29	Bayer Healthcare Ag	2-Aminoethoxyessigsäure-Derivate und ihre Verwendung
RU2578602C2 (ru)	2005-10-04	2016-03-27	Байер Интеллектуэль Проперти Гмбх	Способ получения 5-хлор-n-(5s)-2-оксо-3-[4-(3-оксо-морфолинил)-фенил]-1,3-оксазолидин-5-ил}-метил)-2-тиофенкарбоксамида в модификации ii (варианты)
DE102005047561A1 (de)	2005-10-04	2007-04-05	Bayer Healthcare Ag	Feste, oral applizierbare pharmazeutische Darreichungsformen mit schneller Wirkstofffreisetzung
WO2009120789A1 (en)	2008-03-26	2009-10-01	Global Alliance For Tb Drug Development	Bicyclic nitroimidazoles covalently linked to substituted phenyl oxazolidinones
EP3498273A1 (en) *	2017-12-14	2019-06-19	Universität Wien	Pharmaceutical composition for modulating the response of a gaba-a receptor

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1222708A (en) *	1968-10-22	1971-02-17	Delalande Sa	Novel 5-(n-substituted aminomethyl)-2-oxazolidinones and their process of preparation
FR2500450A1 (fr) *	1981-02-25	1982-08-27	Delalande Sa	Nouveaux derives aminomethyl-5 oxazolidiniques, leur procede de preparation et leur application en therapeutique
US4705799A (en) *	1983-06-07	1987-11-10	E. I. Du Pont De Nemours And Company	Aminomethyl oxooxazolidinyl benzenes useful as antibacterial agents
ES8506659A1 (es) *	1983-06-07	1985-08-01	Du Pont	Un procedimiento para la preparacion de nuevos derivados del amino-metil-oxooxazolidinil-benzeno.
CA1260948A (en) *	1984-12-05	1989-09-26	E. I. Du Pont De Nemours And Company	Aminomethyl oxooxazolidinyl benzene derivatives useful as antibacterial agents

1988
- 1988-10-18 CA CA000580498A patent/CA1317594C/en not_active Expired - Fee Related
- 1988-10-18 DE DE88117304T patent/DE3884563T2/de not_active Expired - Fee Related
- 1988-10-18 EP EP88117304A patent/EP0316594B1/en not_active Expired - Lifetime
- 1988-10-18 ES ES88117304T patent/ES2059467T3/es not_active Expired - Lifetime
- 1988-10-18 AT AT88117304T patent/ATE95176T1/de active
- 1988-10-19 NZ NZ226631A patent/NZ226631A/xx unknown
- 1988-10-19 AU AU24043/88A patent/AU617697B2/en not_active Ceased
- 1988-10-19 MY MYPI88001186A patent/MY103433A/en unknown
- 1988-10-20 JP JP63263043A patent/JPH01135777A/ja active Pending
- 1988-10-20 IL IL88107A patent/IL88107A/xx not_active IP Right Cessation
- 1988-10-20 DK DK584188A patent/DK584188A/da not_active Application Discontinuation
- 1988-10-20 ZA ZA887853A patent/ZA887853B/xx unknown
- 1988-10-20 PT PT88811A patent/PT88811B/pt not_active IP Right Cessation
- 1988-10-20 HU HU885417A patent/HU201915B/hu not_active IP Right Cessation
- 1988-10-20 RU SU884356676A patent/RU1801109C/ru active
- 1988-10-20 FI FI884849A patent/FI884849A/fi not_active Application Discontinuation
- 1988-10-20 KR KR1019880013655A patent/KR890006603A/ko not_active Application Discontinuation
- 1988-10-20 NO NO88884676A patent/NO884676L/no unknown

Also Published As

Publication number	Publication date
EP0316594B1 (en)	1993-09-29
AU2404388A (en)	1989-04-27
CA1317594C (en)	1993-05-11
HU201915B (en)	1991-01-28
PT88811B (pt)	1993-04-30
IL88107A (en)	1993-02-21
HUT52075A (en)	1990-06-28
KR890006603A (ko)	1989-06-14
RU1801109C (ru)	1993-03-07
NO884676L (no)	1989-04-24
NO884676D0 (no)	1988-10-20
DE3884563D1 (de)	1993-11-04
ES2059467T3 (es)	1994-11-16
FI884849A0 (fi)	1988-10-20
AU617697B2 (en)	1991-12-05
JPH01135777A (ja)	1989-05-29
DK584188A (da)	1989-04-22
IL88107A0 (en)	1989-06-30
ZA887853B (en)	1990-06-27
DE3884563T2 (de)	1994-02-17
EP0316594A1 (en)	1989-05-24
ATE95176T1 (de)	1993-10-15
MY103433A (en)	1993-06-30
FI884849A (fi)	1989-04-22
NZ226631A (en)	1991-01-29

Publication	Publication Date	Title
DK584188A (da)	1989-04-22	Aminomethyl-oxooxazolidinyl-ethenylbenzenderivater, deres fremstilling og anvendelse i laegemidler til bekaempelse af infektioner
DK561885D0 (da)	1985-12-04	Aminomethyl-oxooxazolidinyl-benzenderivater og deres anvendelse som antibakterielle midler
IL88047A (en)	1992-11-15	Aminomethyl oxooxazolidinyl aroylbenzene derivatives,their preparation and pharmaceutical compositions containing them
NO2002009I2 (no)	2004-10-11	Tiotropium
DK368480A (da)	1981-03-02	Optisk aktive 1,4-dihydropyridiner fremgangsmaader til deres fremstilling og deres anvendelse som laegemidler
DK617388A (da)	1989-05-07	1,1-dimethyl-2-oxa-4-aminoindanderivater, deres fremstilling og anvendelse som fungicider
DK55088A (da)	1988-08-05	3,4-dihydro-2h-benzo(b)pyraner, deres fremstilling og anvendelse som laegemidler
NO890187D0 (no)	1989-01-16	2-(3,4-dihydroksyfenyl)etylaminer, deres fremstilling og anvendelse som farmasoeytika.
DK656588A (da)	1989-05-26	Substituerede hydroxylaminer, deres fremstilling og anvendelse som laegemidler, samt ved fremstillingen anvendelige mellemprodukter og fremstilling deraf
DK219685D0 (da)	1985-05-17	Heterocycliske forbindelser, deres fremstilling og anvendelse som laegemidler
BR8903996A (pt)	1990-03-20	Dioxolanos substituidos,processo para sua preparacao,composicoes microbicidas,processo para combater microorganismos e para a preparacao de composicoes oxiranil-dioxolanos,prcesso para sua preparacao,dioxolanil-cetonas,processo para sua preparacao oxiranil-cetonas,processo para sua preparacao,alfa-halogeno-cetonas,processo para sua preparacao
DK448186D0 (da)	1986-09-18	N-substituerede 3,4,5,6-tetrahydrophtalimider, deres fremstilling og anvendelse som herbicider
DK284688A (da)	1988-11-27	Beta-lactam-forbindelser, deres fremstilling og anvendelse som laegemidler
DK296085A (da)	1985-12-30	7-oxo-4-thia-l-azabicyclo(3,2,0)hept-2-en-derivater, deres fremstilling og anvendelse som antibakterielle midler, samt ved fremstillingen anvendelige mellemprodukter
DK159085D0 (da)	1985-04-09	2-(alkoximinoalkyloxycarbonyl)-phenylsulfonylurinstoffer, deres fremstilling og anvendelse som herbicider og fungicider
ATE73784T1 (de)	1992-04-15	Fungizide 2-anilinthiazoline.
KR890701578A (ko)	1989-12-21	신규의 티오펜 화합물 및 그들의 제법
DK134988A (da)	1988-09-14	Thiazolylderivater, deres fremstilling og anvendelse som herbicider
TH4707A (th)	1988-03-01	เฟนนิลเบนโซอิลยูเรีย

Legal Events

Date	Code	Title	Description
1995-06-26	AHB	Application shelved due to non-payment