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DK561885D0 - Aminomethyl-oxooxazolidinyl-benzenderivater og deres anvendelse som antibakterielle midler - Google Patents

Aminomethyl-oxooxazolidinyl-benzenderivater og deres anvendelse som antibakterielle midler

Info

Publication number
DK561885D0
DK561885D0 DK561885A DK561885A DK561885D0 DK 561885 D0 DK561885 D0 DK 561885D0 DK 561885 A DK561885 A DK 561885A DK 561885 A DK561885 A DK 561885A DK 561885 D0 DK561885 D0 DK 561885D0
Authority
DK
Denmark
Prior art keywords
antibacterials
aminomethyl
benzene derivatives
oxooxazolidinyl
oxooxazolidinyl benzene
Prior art date
Application number
DK561885A
Other languages
English (en)
Other versions
DK561885A (da
DK169103B1 (da
Inventor
Walter Adelman Gregory
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of DK561885D0 publication Critical patent/DK561885D0/da
Publication of DK561885A publication Critical patent/DK561885A/da
Application granted granted Critical
Publication of DK169103B1 publication Critical patent/DK169103B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/24—Oxygen atoms attached in position 2 with hydrocarbon radicals, substituted by oxygen atoms, attached to other ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DK561885A 1984-12-05 1985-12-04 Aminomethyl-oxooxazolidinyl-benzenforbindelser, en fremgangsmåde til fremstilling deraf og farmaceutiske præparater indeholdende disse forbindelser DK169103B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67674584A 1984-12-05 1984-12-05
US67674584 1984-12-05

Publications (3)

Publication Number Publication Date
DK561885D0 true DK561885D0 (da) 1985-12-04
DK561885A DK561885A (da) 1986-06-06
DK169103B1 DK169103B1 (da) 1994-08-15

Family

ID=24715801

Family Applications (1)

Application Number Title Priority Date Filing Date
DK561885A DK169103B1 (da) 1984-12-05 1985-12-04 Aminomethyl-oxooxazolidinyl-benzenforbindelser, en fremgangsmåde til fremstilling deraf og farmaceutiske præparater indeholdende disse forbindelser

Country Status (17)

Country Link
EP (1) EP0184170B1 (da)
JP (1) JPS61134379A (da)
AT (1) ATE68491T1 (da)
AU (1) AU611627B2 (da)
CA (1) CA1260948A (da)
DE (1) DE3584427D1 (da)
DK (1) DK169103B1 (da)
ES (1) ES8705404A1 (da)
FI (1) FI82453C (da)
GR (1) GR852919B (da)
HU (1) HU194195B (da)
IE (1) IE58325B1 (da)
NO (1) NO164540C (da)
NZ (1) NZ214437A (da)
PT (1) PT81610B (da)
SU (1) SU1528317A3 (da)
ZA (1) ZA859329B (da)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8506659A1 (es) * 1983-06-07 1985-08-01 Du Pont Un procedimiento para la preparacion de nuevos derivados del amino-metil-oxooxazolidinil-benzeno.
US4801600A (en) * 1987-10-09 1989-01-31 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
US5036092A (en) * 1987-10-09 1991-07-30 Du Pont Merck Pharmaceutical Aminomethyl oxooxazolidinyl azacycloalkylbenzene derivatives useful as antibacterial agents
US5039690A (en) * 1987-10-09 1991-08-13 Du Pont Merck Pharmaceutical Company Aminomethyl oxooxazolidinyl oxa or thia cycloalkylbenzene derivatives useful as antibacterial agents
US4965268A (en) * 1987-10-09 1990-10-23 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
US4985429A (en) * 1987-10-09 1991-01-15 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
US5036093A (en) * 1987-10-09 1991-07-30 Du Pont Merck Pharmaceutical Aminomethyl oxooxazolidinyl azacycloalkylbenzene derivatives useful as antibacterial agents
US5032605A (en) * 1987-10-09 1991-07-16 Du Pont Merck Pharmaceutical Company Aminomethyl oxooxazolidinyl oxa or thia cycloalkylbenzene derivatives useful as antibacterial agents
US4921869A (en) * 1987-10-09 1990-05-01 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
US4942183A (en) * 1987-10-16 1990-07-17 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl aroylbenzene derivatives useful as antibacterial agents
CA1320730C (en) * 1987-10-16 1993-07-27 The Du Pont Merck Pharmaceutical Company Aminomethyl oxooxazolidinyl aroylbenzene derivatives useful as antibacterial agents
US4977173A (en) * 1987-10-21 1990-12-11 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl ethenylbenzene derivatives useful as antibacterial agents
CA1317594C (en) * 1987-10-21 1993-05-11 Chung-Ho Park Aminomethyloxooxazolidinyl ethenylbenzene derivatives useful as antibacterial agents
US4948801A (en) * 1988-07-29 1990-08-14 E. I. Du Pont De Nemours And Company Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
US5225565A (en) * 1988-09-15 1993-07-06 The Upjohn Company Antibacterial 3-(fused-ring substituted)phenyl-5β-amidomethyloxazolidin-2-ones
ES2157934T3 (es) * 1988-09-15 2001-09-01 Upjohn Co Fenil-5-beta-amidometiloxazolidin-2-onas sustituidas con nitrogeno en la posicion 3.
US5182403A (en) * 1988-09-15 1993-01-26 The Upjohn Company Substituted 3(5'indazolyl) oxazolidin-2-ones
US5231188A (en) * 1989-11-17 1993-07-27 The Upjohn Company Tricyclic [6.5.51]-fused oxazolidinone antibacterial agents
AU667198B2 (en) * 1991-11-01 1996-03-14 Pharmacia & Upjohn Company Substituted aryl- and heteroarylphenyloxazolidinones useful as antibacterial agents
KR100276382B1 (ko) * 1992-12-08 2000-12-15 로렌스 티. 마이젠헬더 트로폰-치환된 페닐옥사졸리디논 항균제
MY115155A (en) * 1993-09-09 2003-04-30 Upjohn Co Substituted oxazine and thiazine oxazolidinone antimicrobials.
US5688792A (en) * 1994-08-16 1997-11-18 Pharmacia & Upjohn Company Substituted oxazine and thiazine oxazolidinone antimicrobials
GB9601666D0 (en) * 1996-01-27 1996-03-27 Zeneca Ltd Chemical compounds
GB9702213D0 (en) 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
GB9609919D0 (en) * 1996-05-11 1996-07-17 Zeneca Ltd Chemical compounds
KR20010013192A (ko) * 1997-05-30 2001-02-26 로렌스 티. 마이젠헬더 티오카보닐 작용기를 갖는 옥사졸리디논 항균제
US6255304B1 (en) 1997-05-30 2001-07-03 Pharmacia & Upjohn Company Oxazolidinone antibacterial agents having a thiocarbonyl functionality
GB9717804D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9717807D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9725244D0 (en) 1997-11-29 1998-01-28 Zeneca Ltd Chemical compounds
JP2002501059A (ja) * 1998-01-23 2002-01-15 ファルマシア・アンド・アップジョン・カンパニー オキサゾリジノンの組合せライブラリー、組成物および調製方法
US7002020B1 (en) 1998-01-23 2006-02-21 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
US6562844B2 (en) 1998-01-23 2003-05-13 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
GB9928568D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
US6518285B2 (en) * 1999-12-21 2003-02-11 Ortho Mcneil Pharmaceutical, Inc. Piperidinyloxy and pyrrolidinyloxy oxazolidinone antibacterials
GB0009803D0 (en) 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
US6410728B1 (en) * 2000-08-31 2002-06-25 Abbott Laboratories Oxazolidinone chemotherapeutic agents
EP1578723A4 (en) * 2001-10-18 2006-11-02 Univ Michigan State Process for the preparation of oxazolidinones and method of use thereof
AU2003207340A1 (en) 2002-02-28 2003-09-09 Astrazeneca Ab 3-cyclyl-5-(nitrogen-containing 5-membered ring) methyl-oxazolidinone derivatives and their use as antibacterial agents
KR20040086465A (ko) * 2002-02-28 2004-10-08 아스트라제네카 아베 화합물
US10533000B2 (en) 2011-05-26 2020-01-14 Sunovion Pharmaceuticals, Inc. Metabotrophic glutamate receptor 5 modulators and methods of use thereof
WO2015068173A1 (en) * 2013-11-08 2015-05-14 Lee Pharma Limited Novel oxazolidinone antibacterial compound

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1222708A (en) * 1968-10-22 1971-02-17 Delalande Sa Novel 5-(n-substituted aminomethyl)-2-oxazolidinones and their process of preparation
USRE29607E (en) 1969-03-18 1978-04-11 Delalande S. A. Derivatives of 5-hydroxymethyl-3-substituted-2-oxazolidinones, process of preparation thereof and therapeutic application
LU80081A1 (fr) 1977-08-26 1979-05-15 Delalande Sa Nouvelles hydroxymethyl-5 oxazolidinones-2,leur procede de preparation et leur application therapeutique
US4128654A (en) 1978-02-10 1978-12-05 E. I. Du Pont De Nemours And Company 5-Halomethyl-3-phenyl-2-oxazolidinones
US4340606A (en) 1980-10-23 1982-07-20 E. I. Du Pont De Nemours And Company 3-(p-Alkylsulfonylphenyl)oxazolidinone derivatives as antibacterial agents
FR2500450A1 (fr) 1981-02-25 1982-08-27 Delalande Sa Nouveaux derives aminomethyl-5 oxazolidiniques, leur procede de preparation et leur application en therapeutique
AU560666B2 (en) * 1981-12-04 1987-04-16 E.I. Du Pont De Nemours And Company P(2-oxo oxazolidinyl)benzene sulphonamides
US4461773A (en) 1982-09-15 1984-07-24 E. I. Dupont De Nemours And Company P-Oxooxazolidinylbenzene compounds as antibacterial agents
ES8506659A1 (es) * 1983-06-07 1985-08-01 Du Pont Un procedimiento para la preparacion de nuevos derivados del amino-metil-oxooxazolidinil-benzeno.

Also Published As

Publication number Publication date
ES549579A0 (es) 1987-05-01
FI82453C (fi) 1991-03-11
ES8705404A1 (es) 1987-05-01
EP0184170B1 (en) 1991-10-16
PT81610B (pt) 1988-04-21
NZ214437A (en) 1989-01-06
FI854804A (fi) 1986-06-06
EP0184170A3 (en) 1987-09-02
JPS61134379A (ja) 1986-06-21
ZA859329B (en) 1987-08-26
FI82453B (fi) 1990-11-30
IE853047L (en) 1986-06-05
PT81610A (en) 1986-01-01
DK561885A (da) 1986-06-06
EP0184170A2 (en) 1986-06-11
AU5081685A (en) 1987-06-11
ATE68491T1 (de) 1991-11-15
SU1528317A3 (ru) 1989-12-07
AU611627B2 (en) 1991-06-20
NO164540B (no) 1990-07-09
FI854804A0 (fi) 1985-12-04
NO164540C (no) 1990-10-17
NO854883L (no) 1986-06-06
GR852919B (da) 1986-04-07
HU194195B (en) 1988-01-28
DK169103B1 (da) 1994-08-15
CA1260948A (en) 1989-09-26
DE3584427D1 (de) 1991-11-21
HUT39436A (en) 1986-09-29
IE58325B1 (en) 1993-09-08

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed