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DK566784A - Substituerede trans-1,2-diaminocyclohexylamidforbindelser - Google Patents

Substituerede trans-1,2-diaminocyclohexylamidforbindelser Download PDF

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Publication number
DK566784A
DK566784A DK566784A DK566784A DK566784A DK 566784 A DK566784 A DK 566784A DK 566784 A DK566784 A DK 566784A DK 566784 A DK566784 A DK 566784A DK 566784 A DK566784 A DK 566784A
Authority
DK
Denmark
Prior art keywords
diaminocyclohexylamide
compounds
substituted trans
trans
substituted
Prior art date
Application number
DK566784A
Other languages
English (en)
Other versions
DK566784D0 (da
Inventor
David C Horwell
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of DK566784D0 publication Critical patent/DK566784D0/da
Publication of DK566784A publication Critical patent/DK566784A/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK566784A 1983-12-06 1984-11-29 Substituerede trans-1,2-diaminocyclohexylamidforbindelser DK566784A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55873783A 1983-12-06 1983-12-06
US06/669,921 US4598087A (en) 1983-12-06 1984-11-13 Substituted trans-1,2-diaminocyclohexyl amide compounds

Publications (2)

Publication Number Publication Date
DK566784D0 DK566784D0 (da) 1984-11-29
DK566784A true DK566784A (da) 1985-06-07

Family

ID=27071831

Family Applications (1)

Application Number Title Priority Date Filing Date
DK566784A DK566784A (da) 1983-12-06 1984-11-29 Substituerede trans-1,2-diaminocyclohexylamidforbindelser

Country Status (17)

Country Link
US (1) US4598087A (da)
EP (1) EP0146297B1 (da)
AR (1) AR240798A1 (da)
AU (1) AU565237B2 (da)
CA (1) CA1235122A (da)
DE (1) DE3469168D1 (da)
DK (1) DK566784A (da)
ES (1) ES538244A0 (da)
FI (1) FI844752L (da)
GR (1) GR81172B (da)
HU (1) HU194547B (da)
IL (1) IL73660A (da)
NO (1) NO844854L (da)
NZ (1) NZ210441A (da)
OA (1) OA07884A (da)
PH (1) PH20657A (da)
PT (1) PT79628B (da)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4737493A (en) * 1985-07-01 1988-04-12 Warner-Lambert Company 7-((substituted)amino)-8-((substituted)carbonyl)-methylamino)-1-oxaspiro(4,5)decanes as analgesic agents
US4663343A (en) * 1985-07-19 1987-05-05 Warner-Lambert Company Substituted naphthalenyloxy-1,2-diaminocyclohexyl amide compounds
EP0232612B1 (en) * 1985-12-23 1990-04-04 Dr. Lo. Zambeletti S.p.A. Azacyclic compounds, processes for their preparation, and their use as pharmaceuticals
GB8608818D0 (en) * 1986-04-11 1986-05-14 Reckitt & Colmann Prod Ltd Pharmaceutical compositions
FR2617164B1 (fr) * 1987-06-25 1989-11-10 Roussel Uclaf Nouveaux derives de la decahydroquinoleine, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant
FR2617481B1 (fr) * 1987-07-03 1989-11-10 Roussel Uclaf Nouveaux derives de la tetrahydropyridine, leur procede de preparation et les intermediaires de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant
US4855316A (en) * 1988-02-18 1989-08-08 Warner-Lambert Company 1,2-diamino-4,5-dimethoxycyclohexyl amide analgesic compounds
AU626949B2 (en) * 1988-12-06 1992-08-13 Warner-Lambert Company 2-amino-4 or 5-methoxycyclohexyl amides useful as analgesics
US5051428A (en) * 1988-12-06 1991-09-24 Warner-Lambert Company 2-amino-4 or 5-methoxycyclohexyl amides useful as analgesics
US5063242A (en) * 1989-04-21 1991-11-05 Warner-Lambert Company 7-((substituted)amino)-8-((substituted)carbonyl)-methylamino-1-oxaspiro[4,5]decanes as diuretics antiinflammatory, and cerebrovascular agents
US4965278A (en) 1989-04-21 1990-10-23 Warner-Lambert Company 7-(substituted)amino)-8-((substituted)carbonyl)-methylamino)-1-oxaspiro[4,5]decanes as diuretics antiiflammatory, and cerebrovascular agents
AU651641B2 (en) * 1991-12-27 1994-07-28 Warner-Lambert Company 2-amino-mono-methoxycyclohexyl amides useful as analgesics
EP0552386A1 (en) * 1992-01-13 1993-07-28 Warner-Lambert Company 2-Amino-3 or 6-methoxycyclohexyl amide derivatives
EP0632806B1 (en) * 1992-03-26 1997-07-02 The University Of British Columbia Aminocyclohexylamides for antiarrhythmic and anaesthetic uses
US5506257A (en) * 1992-03-26 1996-04-09 University Of British Columbia Aminocyclohexylamides for antiarrhythmic and anaesthetic uses
US5317028A (en) * 1992-09-08 1994-05-31 Warner-Lambert Co. 7-((substituted)amino)-8((substituted)carbonyl)-methylamino-1-oxaspiro(4,5)decanes useful in Parkinson's disease, dystonia, and other movement disorders
US5968968A (en) * 1996-07-24 1999-10-19 Warner-Lambert Company Diphenyl-cyclopropenes as selective K-agonists
HU229993B1 (en) 1998-04-01 2015-04-28 Cardiome Pharma Corp Aminocyclohexyl ether compounds and uses thereof
US7053087B1 (en) 1999-03-04 2006-05-30 Cardiome Pharma Corp. Aminocycloalkyl cinnamide compounds for arrhythmia and analgesics and anesthetics
US7507545B2 (en) 1999-03-31 2009-03-24 Cardiome Pharma Corp. Ion channel modulating activity method
US7425537B2 (en) 2000-08-22 2008-09-16 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services SH2 domain binding inhibitors
US7057053B2 (en) 2000-10-06 2006-06-06 Cardiome Pharma Corp. Ion channel modulating compounds and uses thereof
US7524879B2 (en) * 2000-10-06 2009-04-28 Cardiome Pharma Corp. Ion channel modulating compounds and uses thereof
US20090041841A1 (en) * 2003-05-02 2009-02-12 Cardiome Pharma Corp. Controlled release tablet formulations for the prevention of arrhythmias
US7345086B2 (en) * 2003-05-02 2008-03-18 Cardiome Pharma Corp. Uses of ion channel modulating compounds
JP4919661B2 (ja) * 2003-05-02 2012-04-18 カーディオム ファーマ コーポレイション アミノシクロヘキシルエーテル化合物およびそれらの用途
US7674820B2 (en) * 2003-08-07 2010-03-09 Cardiome Pharma Corp. Ion channel modulating activity I
US7345087B2 (en) * 2003-10-31 2008-03-18 Cardiome Pharma Corp. Aminocyclohexyl ether compounds and uses thereof
US8058304B2 (en) * 2004-04-01 2011-11-15 Cardiome Pharma Corp. Merged ion channel modulating compounds and uses thereof
US7977373B2 (en) 2004-04-01 2011-07-12 Cardiome Pharma Corp. Prodrugs of ion channel modulating compounds and uses thereof
ES2483940T3 (es) * 2004-11-08 2014-08-08 Cardiome Pharma Corp. Un nuevo régimen de dosificación para compuestos moduladores del canal iónico para el tratamiento de la fibrilación auricular aguda en un ser humano

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4098904A (en) * 1976-11-12 1978-07-04 The Upjohn Company Analgesic n-(2-aminocycloaliphatic)benzamides
US4145435A (en) * 1976-11-12 1979-03-20 The Upjohn Company 2-aminocycloaliphatic amide compounds
GB2096607B (en) * 1981-04-09 1985-02-27 Upjohn Co Aminocycloalkyl amides
US4359476A (en) * 1981-04-09 1982-11-16 The Upjohn Company Adjacently substituted cycloalkane-amide analgesics

Also Published As

Publication number Publication date
AR240798A1 (es) 1991-02-28
AU3630684A (en) 1985-06-13
FI844752A0 (fi) 1984-12-03
OA07884A (en) 1986-11-20
US4598087A (en) 1986-07-01
NZ210441A (en) 1989-01-27
DK566784D0 (da) 1984-11-29
PT79628B (en) 1986-12-22
EP0146297A1 (en) 1985-06-26
FI844752L (fi) 1985-06-07
IL73660A (en) 1987-12-31
ES8607914A1 (es) 1986-01-01
EP0146297B1 (en) 1988-02-03
PT79628A (en) 1985-01-01
GR81172B (en) 1985-04-04
ES538244A0 (es) 1986-01-01
CA1235122A (en) 1988-04-12
NO844854L (no) 1985-06-07
AU565237B2 (en) 1987-09-10
PH20657A (en) 1987-03-16
DE3469168D1 (en) 1988-03-10
HU194547B (en) 1988-02-29
HUT36106A (en) 1985-08-28
AR240798A2 (es) 1991-02-28

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment