[go: up one dir, main page]

DK3810128T3 - Sammensætninger til behandling og/eller forebyggelse af proteinaggregeringssygdomme - Google Patents

Sammensætninger til behandling og/eller forebyggelse af proteinaggregeringssygdomme Download PDF

Info

Publication number
DK3810128T3
DK3810128T3 DK19730826.5T DK19730826T DK3810128T3 DK 3810128 T3 DK3810128 T3 DK 3810128T3 DK 19730826 T DK19730826 T DK 19730826T DK 3810128 T3 DK3810128 T3 DK 3810128T3
Authority
DK
Denmark
Prior art keywords
prevention
compositions
treatment
protein aggregation
aggregation diseases
Prior art date
Application number
DK19730826.5T
Other languages
English (en)
Inventor
Mercedes M Pérez-Jiménez
Manuel J Muñoz
Ángel M Carrión
Original Assignee
Univ Pablo De Olavide
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pablo De Olavide filed Critical Univ Pablo De Olavide
Application granted granted Critical
Publication of DK3810128T3 publication Critical patent/DK3810128T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/366Lactones having six-membered rings, e.g. delta-lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/366Lactones having six-membered rings, e.g. delta-lactones
    • A61K31/37Coumarins, e.g. psoralen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
DK19730826.5T 2018-06-19 2019-06-19 Sammensætninger til behandling og/eller forebyggelse af proteinaggregeringssygdomme DK3810128T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18382439 2018-06-19
PCT/EP2019/066271 WO2019243453A1 (en) 2018-06-19 2019-06-19 Compositions for treating and/or preventing protein-aggregation diseases

Publications (1)

Publication Number Publication Date
DK3810128T3 true DK3810128T3 (da) 2022-10-31

Family

ID=62716030

Family Applications (1)

Application Number Title Priority Date Filing Date
DK19730826.5T DK3810128T3 (da) 2018-06-19 2019-06-19 Sammensætninger til behandling og/eller forebyggelse af proteinaggregeringssygdomme

Country Status (13)

Country Link
US (1) US20210251953A1 (da)
EP (2) EP4094754A1 (da)
JP (2) JP2021528442A (da)
CN (2) CN118845759A (da)
AU (1) AU2019291061A1 (da)
BR (1) BR112020026066A2 (da)
CA (1) CA3103834A1 (da)
DK (1) DK3810128T3 (da)
ES (1) ES2931815T3 (da)
MX (1) MX2020014070A (da)
PL (1) PL3810128T3 (da)
PT (1) PT3810128T (da)
WO (1) WO2019243453A1 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3070446A1 (en) 2017-07-25 2019-01-31 Immutics, Inc. Treating cancer by blocking the interaction of tim-3 and its ligand
EP3988096A1 (en) 2020-10-26 2022-04-27 Universidad Pablo de Olavide OTRI Sulfated c19 steroid hormones to treat and/or prevent proteotoxicity in protein-aggregation diseases
CN112552272B (zh) * 2020-12-22 2023-06-27 四川大学 香豆素类化合物及其制备方法和应用、药物组合物

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9603325D0 (en) 1996-02-16 1996-04-17 Imperial College A compound
US5556847A (en) * 1994-10-27 1996-09-17 Duquesne University Of The Holy Ghost Methods of effecting memory enhancement mediated by steroid sulfatase inhibitors
JP4320089B2 (ja) * 1999-07-06 2009-08-26 あすか製薬株式会社 フェニルスルファメート誘導体
EP1311272B1 (en) * 2000-03-03 2006-11-22 Eisai Co., Ltd. Novel methods using cholinesterase inhibitors
US20060183776A9 (en) * 2000-03-03 2006-08-17 Eisai Co., Ltd. Liquid dosage formulations of donepezil
GB0511190D0 (en) * 2005-06-01 2005-07-06 Sterix Ltd Use
ES2514140B1 (es) * 2013-03-26 2015-08-03 Universidad Pablo De Olavide Uso del inhibidor de sulfatasas esteroideas STX64 para el tratamiento del envejecimiento
KR20170092634A (ko) * 2014-12-05 2017-08-11 에이엔2에이치 디스커버리 리미티드 파킨 리가제 활성화 방법 및 조성물
BR112018008839A8 (pt) 2015-10-30 2019-02-26 Ultragenyx Pharmaceutical Inc métodos e composições para o tratamento da amiloidose
US10780094B2 (en) * 2016-07-22 2020-09-22 New York University Use of carbonic anhydrase inhibitors for treatment of neurological and psychiatric disorders

Also Published As

Publication number Publication date
JP2024059803A (ja) 2024-05-01
EP3810128A1 (en) 2021-04-28
MX2020014070A (es) 2021-05-27
BR112020026066A2 (pt) 2021-03-23
JP2021528442A (ja) 2021-10-21
US20210251953A1 (en) 2021-08-19
CN118845759A (zh) 2024-10-29
EP3810128B1 (en) 2022-08-03
PL3810128T3 (pl) 2023-01-30
PT3810128T (pt) 2022-11-09
CN112601521A (zh) 2021-04-02
WO2019243453A1 (en) 2019-12-26
CA3103834A1 (en) 2019-12-26
EP4094754A1 (en) 2022-11-30
AU2019291061A1 (en) 2021-02-04
ES2931815T3 (es) 2023-01-02

Similar Documents

Publication Publication Date Title
CL2020002043A1 (es) Métodos y composiciones para la entrega de proteínas terapeuticas.
IL280710A (en) Methods and compositions for treating mitochondrial disease or disorders and heteroplasmy
DK3402499T3 (da) Sammensætninger og fremgangsmåder til behandlingen af type 1 diabetes
DK3889145T3 (da) 8-cyano-5-piperidino-quinoliner som TLR7/8-antagonister og anvendelser deraf til behandling af immunsygdomme
IL281277A (en) Preparations and methods for treating viral infections
EP3263132C0 (en) Composition for treating il-6-related diseases
HK1251482A1 (zh) 用於治療補體介導的疾病的組合物和方法
DK3464266T3 (da) Substituerede indazoler, der er anvendelige til behandling og forebyggelse af allergiske og/eller inflammatoriske sygdomme hos dyr
EP3890725A4 (en) Compositions for treating dermatological diseases
EP3810124A4 (en) COMPOSITION INTENDED FOR THE TREATMENT OF DRY EYE SYNDROME AND MEIBOMITIS
DK3759083T3 (da) 2,4-diaminoquinazolinderivater og anvendelse deraf til behandling af virusinfektioner, cancer eller allergier
DK3807316T3 (da) Sammensætninger og fremgangsmåder til behandling af cancer
DK3310190T3 (da) Sammensætning til behandling af kød og anvendelse af denne
EP3655036C0 (en) COMPOSITIONS FOR THE TREATMENT OF STRESS-RELATED DISORDERS
EP3398437A4 (en) PESTICIDE COMPOSITION CONTAINING METCONAZOLE FOR PREVENTING AND TREATING FUSARIOSIS OF PPE AND ITS APPLICATION
DK3522873T3 (da) Sammensætninger og fremgangsmåder til behandlingen af xerostomi
EP3573620A4 (en) COMPOSITIONS FOR THE TREATMENT OF HYPERTENSION
EP3775261A4 (en) TARGET BOND FRACTION COMPOSITIONS AND METHODS OF USE
DK3810128T3 (da) Sammensætninger til behandling og/eller forebyggelse af proteinaggregeringssygdomme
EP3634394A4 (en) COMPOSITIONS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES
DK3373922T3 (da) Sammensætninger og fremgangsmåder til anvendelse i behandlingen af homocystinuri
DK3280401T3 (da) Sammensætninger til behandling og/eller forebyggelse af celle- eller vævsnekrose specielt rettet mod kathepsin c og/eller cela1 og/eller cela3a og/eller strukturelt relaterede enzymer dertil
DK3197556T3 (da) Sammensætning til forebyggelse og/eller behandling af allergisymptomer
EP3597198A4 (en) COMPOSITION FOR THE TREATMENT OF JOINT DISEASES, AND KIT CONTAINING THIS COMPOSITION
IT201700121764A1 (it) Composizione per il trattamento e/o la prevenzione di patologie neurodegenerative.