[go: up one dir, main page]

DK3374495T3 - Forbedrede fremgangsmåder til vævsfremstilling - Google Patents

Forbedrede fremgangsmåder til vævsfremstilling Download PDF

Info

Publication number
DK3374495T3
DK3374495T3 DK16864922.6T DK16864922T DK3374495T3 DK 3374495 T3 DK3374495 T3 DK 3374495T3 DK 16864922 T DK16864922 T DK 16864922T DK 3374495 T3 DK3374495 T3 DK 3374495T3
Authority
DK
Denmark
Prior art keywords
improved methods
tissue manufacture
tissue
manufacture
methods
Prior art date
Application number
DK16864922.6T
Other languages
English (en)
Inventor
Kelsey Nicole Retting
Sharon C Presnell
Shelby Marie King
Deborah Lynn Greene Nguyen
Original Assignee
Organovo Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US14/936,580 external-priority patent/US20170130192A1/en
Application filed by Organovo Inc filed Critical Organovo Inc
Application granted granted Critical
Publication of DK3374495T3 publication Critical patent/DK3374495T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
    • C12N5/0698—Skin equivalents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C64/00—Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
    • B29C64/10—Processes of additive manufacturing
    • B29C64/106—Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material
    • B29C64/112—Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material using individual droplets, e.g. from jetting heads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y70/00—Materials specially adapted for additive manufacturing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y80/00—Products made by additive manufacturing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
    • B41J—TYPEWRITERS; SELECTIVE PRINTING MECHANISMS, i.e. MECHANISMS PRINTING OTHERWISE THAN FROM A FORME; CORRECTION OF TYPOGRAPHICAL ERRORS
    • B41J2/00—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed
    • B41J2/005—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed characterised by bringing liquid or particles selectively into contact with a printing material
    • B41J2/01—Ink jet
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0062—General methods for three-dimensional culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0656—Adult fibroblasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00—Other particular articles
    • B29L2031/753—Medical equipment; Accessories therefor
    • B29L2031/7532—Artificial members, protheses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/09—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells
    • C12N2502/091—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells melanocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/09—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells
    • C12N2502/094—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells keratinocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2523/00—Culture process characterised by temperature
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/54—Collagen; Gelatin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2539/00—Supports and/or coatings for cell culture characterised by properties

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Materials Engineering (AREA)
  • Manufacturing & Machinery (AREA)
  • Rheumatology (AREA)
  • Physics & Mathematics (AREA)
  • Mechanical Engineering (AREA)
  • Optics & Photonics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
DK16864922.6T 2015-11-09 2016-11-09 Forbedrede fremgangsmåder til vævsfremstilling DK3374495T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562253064P 2015-11-09 2015-11-09
US14/936,580 US20170130192A1 (en) 2015-11-09 2015-11-09 Methods for tissue fabrication
PCT/US2016/061156 WO2017083402A1 (en) 2015-11-09 2016-11-09 Improved methods for tissue fabrication

Publications (1)

Publication Number Publication Date
DK3374495T3 true DK3374495T3 (da) 2023-05-22

Family

ID=58695226

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16864922.6T DK3374495T3 (da) 2015-11-09 2016-11-09 Forbedrede fremgangsmåder til vævsfremstilling

Country Status (6)

Country Link
US (1) US12037603B2 (da)
EP (1) EP3374495B1 (da)
JP (1) JP7007267B2 (da)
AU (1) AU2016352873B2 (da)
DK (1) DK3374495T3 (da)
WO (1) WO2017083402A1 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20190077407A (ko) 2016-11-10 2019-07-03 오가노보, 인크. 바이오프린팅된 모발 모낭 및 그의 용도
WO2018089743A1 (en) 2016-11-10 2018-05-17 Organovo, Inc. Engineered intestinal tissue and uses thereof
WO2018187380A1 (en) 2017-04-03 2018-10-11 Greene Nguyen Deborah Lynn Use of engineered liver tissue constructs for modeling liver disorders
JP7256494B2 (ja) * 2019-03-06 2023-04-12 国立大学法人大阪大学 細胞組織作製方法および細胞組織作製セット
EP3936238A4 (en) * 2019-03-06 2022-11-30 Osaka University METHOD OF PRODUCTION OF CELLULAR TISSUE, SET OF CELLULAR TISSUE AND CELLULAR TISSUE MANUFACTURED BY THIS PRODUCTION PROCESS
US20220282222A1 (en) 2019-08-23 2022-09-08 Murdoch Children's Research Institute Bio-printed kidney tissue
CN112848296A (zh) * 2021-01-14 2021-05-28 中国医科大学 复合多喷头3d打印成型系统
US20240091808A1 (en) * 2022-09-16 2024-03-21 Lawrence Livermore National Security, Llc High throughput materials screening

Family Cites Families (117)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4759764A (en) 1985-05-24 1988-07-26 Clayton Foundation For Research Peripheral nerve regeneration
US4808435A (en) 1987-04-06 1989-02-28 International Business Machines Corporation Screen printing method for producing lines of uniform width and height
US5099090A (en) 1988-05-11 1992-03-24 Ariel Electronics, Inc. Circuit writer
WO1999001538A1 (en) 1997-07-03 1999-01-14 Massachusetts Institute Of Technology Tissue-engineered constructs
US6401795B1 (en) 1997-10-28 2002-06-11 Sandia Corporation Method for freeforming objects with low-binder slurry
EP2133725B1 (en) 1998-04-21 2018-06-06 University of Connecticut Fabrication method for nanofabrication using multi-photon excitation
US6697694B2 (en) 1998-08-26 2004-02-24 Electronic Materials, L.L.C. Apparatus and method for creating flexible circuits
US7338798B2 (en) 1998-09-15 2008-03-04 The Regents Of The University Of Michigan System and method for forming a cardiac muscle construct
EP1029692B9 (en) 1999-02-17 2003-12-03 Hewlett-Packard Company, A Delaware Corporation Printing apparatus
US6979670B1 (en) 1999-03-10 2005-12-27 Biora Bioex Ab Matrix protein compositions for grafting
US6642243B1 (en) 1999-07-22 2003-11-04 Ashkan Imanzahrai Migraine medicine and method for treating same
JP2001145956A (ja) 1999-11-19 2001-05-29 Meiko:Kk 光硬化性樹脂三次元造形物の積層造形装置及びその積層造形方法
US6503273B1 (en) 1999-11-22 2003-01-07 Cyograft Tissue Engineering, Inc. Tissue engineered blood vessels and methods and apparatus for their manufacture
US6454972B1 (en) 1999-11-24 2002-09-24 Sandia Corporation Solid freeform fabrication using chemically reactive suspensions
US6520997B1 (en) 1999-12-08 2003-02-18 Baxter International Inc. Porous three dimensional structure
US6315469B1 (en) 2000-01-19 2001-11-13 Hewlett-Packard Company Tool and method for adjustment of printhead to platen spacing in a printer
DE10013223C2 (de) 2000-03-13 2002-07-18 Co Don Ag Verfahren zur in vitro-Herstellung von dreidimensionalem, vitalem Knorpel- oder Knochengewebe und dessen Verwendung als Transplantationsmaterial
US20050091576A1 (en) 2003-10-24 2005-04-28 Microsoft Corporation Programming interface for a computer platform
DE10018987A1 (de) 2000-04-17 2001-10-31 Envision Technologies Gmbh Vorrichtung und Verfahren zum Herstellen von dreidimensionalen Objekten
US20020182633A1 (en) 2000-07-11 2002-12-05 Chen Christopher S. Methods of patterning protein and cell adhesivity
US7998735B2 (en) 2000-08-21 2011-08-16 Victorian Tissue Engineering Centre Pty. Ltd. Vascularized tissue graft
US6561607B1 (en) 2000-10-05 2003-05-13 Eastman Kodak Company Apparatus and method for maintaining a substantially constant closely spaced working distance between an inkjet printhead and a printing receiver
US6939489B2 (en) 2001-03-23 2005-09-06 Ivoclar Vivadent Ag Desktop process for producing dental products by means of 3-dimensional plotting
WO2002085246A2 (en) 2001-04-19 2002-10-31 Case Western Reserve University Fabrication of a polymeric prosthetic implant
DE10127225A1 (de) 2001-05-22 2002-11-28 Zeiss Carl Ultraviolettlicht-Abschwächungsfilter
US20030049839A1 (en) 2001-08-01 2003-03-13 The University Of Texas System Transparent multi-channel cell scaffold that creates a cellular and/or molecular gradient
US6986739B2 (en) 2001-08-23 2006-01-17 Sciperio, Inc. Architecture tool and methods of use
US6934600B2 (en) 2002-03-14 2005-08-23 Auburn University Nanotube fiber reinforced composite materials and method of producing fiber reinforced composites
US20100254900A1 (en) 2002-03-18 2010-10-07 Campbell Phil G Biocompatible polymers and Methods of use
US20030175410A1 (en) 2002-03-18 2003-09-18 Campbell Phil G. Method and apparatus for preparing biomimetic scaffold
US6907307B2 (en) 2002-07-02 2005-06-14 3D Systems, Inc. Support volume calculation for a CAD model
AU2003251874A1 (en) 2002-07-12 2004-02-02 Dirk R. Albrecht Three dimensional cell patterned bioploymer scaffolds and method of making the same
US7641898B2 (en) 2003-03-21 2010-01-05 Materials Evolution And Development Usa, Inc. Keratinocyte-fibrocyte concomitant grafting for wound healing
US20040197375A1 (en) 2003-04-02 2004-10-07 Alireza Rezania Composite scaffolds seeded with mammalian cells
US7051654B2 (en) 2003-05-30 2006-05-30 Clemson University Ink-jet printing of viable cells
CA2528134C (en) 2003-06-04 2015-05-12 University Of South Carolina Tissue scaffold having aligned fibrils, apparatus and method for producing the same, and artificial tissue and methods of use thereof
JP4474858B2 (ja) 2003-07-07 2010-06-09 セイコーエプソン株式会社 ギャップ調整装置、これに使用されるキャリブレーション用治具、およびギャップ調整装置を備えた液滴吐出装置、並びに電気光学装置の製造方法
US20050074877A1 (en) 2003-07-28 2005-04-07 Mao Jeremy Jian Biological engineering of articular structures containing both cartilage and bone
FR2859128B1 (fr) 2003-08-29 2006-03-10 Centre Nat Rech Scient Procede et dispositif de fabrication d'un composant multimateriaux tridimensionnel par impression du type jet d'encre
US8043614B2 (en) 2004-03-09 2011-10-25 Ahlfors Jan-Eric W Autogenic living scaffolds and living tissue matrices: methods and uses thereof
DE10353281A1 (de) 2003-11-14 2005-06-16 Bayer Cropscience Ag Wirkstoffkombination mit insektiziden und akariziden Eigenschaften
US20050276791A1 (en) 2004-02-20 2005-12-15 The Ohio State University Multi-layer polymer scaffolds
US8241905B2 (en) 2004-02-24 2012-08-14 The Curators Of The University Of Missouri Self-assembling cell aggregates and methods of making engineered tissue using the same
US20090142307A1 (en) 2004-07-09 2009-06-04 Athanasiou Kyriacos A Shape-Based Approach for Scaffoldless Tissue Engineering
WO2007115337A2 (en) 2006-04-05 2007-10-11 William Marsh Rice University Chondrocyte differentiation from human embryonic stem cells and their use in tissue engineering
WO2006020685A2 (en) 2004-08-11 2006-02-23 Cornell Research Foundation, Inc. Modular fabrication systems and methods
US7651665B2 (en) 2004-09-07 2010-01-26 Hewlett-Packard Development Company, L.P. Microtray for handling biosubstances
US7767446B2 (en) 2004-09-16 2010-08-03 Becton, Dickinson And Company Perfusion bioreactors for culturing cells
KR100606457B1 (ko) 2004-11-11 2006-11-23 한국기계연구원 3차원 프린팅 조형시스템
JP4539316B2 (ja) 2004-12-08 2010-09-08 セイコーエプソン株式会社 ヘッド位置補正方法およびヘッド位置補正装置、並びに液滴吐出装置、電気光学装置の製造方法
US7568904B2 (en) 2005-03-03 2009-08-04 Laser Solutions Co., Ltd. Stereolithography apparatus
JP4729948B2 (ja) 2005-03-09 2011-07-20 ブラザー工業株式会社 液体供給装置、この液体供給装置を備えたインクジェット記録装置
US7780897B2 (en) 2005-04-22 2010-08-24 Board Of Regents, The University Of Texas System Hydrogel constructs using stereolithography
EP2495310A3 (en) 2005-05-24 2013-03-27 The Regents Of the University of California Microscale micropatterned engineered in vitro tissue
EP2093256A3 (en) 2005-07-28 2009-10-14 Carnegie Mellon University Biocompatible polymers and methods of use
US8690957B2 (en) 2005-12-21 2014-04-08 Warsaw Orthopedic, Inc. Bone graft composition, method and implant
US20070200276A1 (en) 2006-02-24 2007-08-30 Micron Technology, Inc. Method for rapid printing of near-field and imprint lithographic features
US7680555B2 (en) 2006-04-03 2010-03-16 Stratasys, Inc. Auto tip calibration in an extrusion apparatus
US20070231787A1 (en) 2006-04-04 2007-10-04 Voelker Mark A Methods and devices for imaging and manipulating biological samples
WO2007124023A2 (en) 2006-04-21 2007-11-01 Wake Forest University Health Sciences Ink-jet printing of tissues
JP4051077B2 (ja) 2006-04-28 2008-02-20 シャープ株式会社 液滴塗布装置、液滴吐出部のギャップ測定方法、および、液滴吐出部のギャップ調整方法
FR2901143B1 (fr) 2006-05-16 2008-10-03 Centre Nat Rech Scient "methode de construction de materiaux vivants fonctionnels, materiaux obtenus et applications"
US7959942B2 (en) 2006-10-20 2011-06-14 Orbusneich Medical, Inc. Bioabsorbable medical device with coating
DE102006053121B3 (de) 2006-11-10 2007-12-27 Eos Gmbh Electro Optical Systems Vorrichtung und Verfahren zum Herstellen eines dreidimensionalen Objektes mittels eines Beschichters für pulverförmiges Aufbaumaterial
US8097455B2 (en) 2007-02-02 2012-01-17 The Regents Of The University Of Michigan System and method for forming skeletal muscle constructs having functional tissue interfaces
WO2008095307A1 (en) * 2007-02-07 2008-08-14 Mcgill University Bioceramic implants having bioactive substance
US8343740B2 (en) 2007-03-29 2013-01-01 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Micro-organ device
US20090117087A1 (en) 2007-04-13 2009-05-07 Wake Forest University Methods and compositions for printing biologically compatible nanotube composites of autologous tissue
CA2688055C (en) 2007-06-07 2018-02-06 Wake Forest University Health Sciences Inkjet gene printing
EP2664444B1 (en) 2007-07-25 2018-03-28 Stratasys Ltd. Solid freeform fabrication using a plurality of modeling materials
ES2375187T3 (es) 2007-08-29 2012-02-27 Vito Nv Procedimiento para producir una construcción de filamentos macroporosa tridimensional basado en la inversión de fase y construcción obtenida de ese modo.
US20090076531A1 (en) 2007-09-18 2009-03-19 Richardson Charles L Method and apparatus for bypass graft
US7923846B2 (en) 2007-11-16 2011-04-12 Stats Chippac Ltd. Integrated circuit package-in-package system with wire-in-film encapsulant
EP2090584A1 (en) 2008-02-13 2009-08-19 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Identification of a novel cysteine-rich cell penetrating peptide
KR100922232B1 (ko) 2008-02-13 2009-10-16 연세대학교 산학협력단 전기수력학 프린팅 기법을 이용한 살아있는 세포의 직접패터닝 방법 및 장치
WO2009102484A2 (en) 2008-02-14 2009-08-20 Wake Forest University Health Sciences Inkjet printing of tissues and cells
US20090248145A1 (en) 2008-03-28 2009-10-01 Nanyang Technological University Method of forming a three-dimensional structure of unidirectionally aligned cells
US8876513B2 (en) 2008-04-25 2014-11-04 3D Systems, Inc. Selective deposition modeling using CW UV LED curing
WO2009154466A1 (en) 2008-06-20 2009-12-23 Universiteit Twente Self-assembling tissue modules
WO2010008905A2 (en) 2008-06-24 2010-01-21 The Curators Of The University Of Missouri Self-assembling multicellular bodies and methods of producing a three-dimensional biological structure using the same
US9097702B2 (en) 2008-07-29 2015-08-04 Cornell University Pathologically relevant tumor microenvironments for high-throughput drug screening
WO2010030964A2 (en) 2008-09-12 2010-03-18 The Brigham And Women's Hospital, Inc. 3-dimensional multi-layered hydrogels and methods of making the same
US20110250688A1 (en) 2008-11-24 2011-10-13 Immunotrex Corporation Three Dimensional Tissue Generation
WO2011038373A2 (en) 2009-09-28 2011-03-31 Virginia Tech Intellectual Properties, Inc. Three-dimensional bioprinting of biosynthetic cellulose (bc) implants and scaffolds for tissue engineering
US8409603B2 (en) 2009-10-01 2013-04-02 University Of South Carolina Compositions and methods for tissue engineering, tissue regeneration and wound healing
KR101812820B1 (ko) 2010-01-08 2017-12-27 웨이크 포리스트 유니버시티 헬스 사이언시즈 전달 시스템
EP2523656A4 (en) 2010-01-15 2013-12-11 Univ Utah Res Found RETICULATED HYDROGELS AND METHODS OF MAKING AND USING THE SAME
CA2788514A1 (en) 2010-02-02 2011-08-11 Gabor Forgacs Engineered biological nerve graft fabrication and application thereof
WO2011107599A1 (en) 2010-03-04 2011-09-09 INSERM (Institut National de la Santé et de la Recherche Médicale) Bioprinting station, assembly comprising such bioprinting station and bioprinting method
GB2478801B (en) 2010-03-16 2012-05-30 Organovo Inc Multilayered vascular tubes
WO2011119059A1 (en) 2010-03-26 2011-09-29 Association For The Advancement Of Tissue Engineering And Cell Based Technologies And Therapies - A4Tec Photo-crosslinked gellan gum-based hydrogels: preparation methods and uses thereof
US9592255B2 (en) 2010-07-01 2017-03-14 The Regents Of The University Of Michigan Scaffold-free three dimensional nerve fibroblast constructs
US20120089238A1 (en) 2010-10-06 2012-04-12 Hyun-Wook Kang Integrated organ and tissue printing methods, system and apparatus
RU2560393C2 (ru) * 2010-10-21 2015-08-20 Органово, Инк. Устройства, системы и способы изготовления ткани
HUE029316T2 (en) 2010-11-04 2017-03-28 Univ Of Pecs Tüdõszövetmodell
DE202011003443U1 (de) 2011-03-02 2011-12-23 Bego Medical Gmbh Vorrichtung zur generativen Herstellung dreidimensionaler Bauteile
CA2828705A1 (en) 2011-03-07 2012-09-13 Wake Forest University Health Sciences Delivery system
GB201105226D0 (en) 2011-03-29 2011-05-11 Univ Leiden Methods
JP5599356B2 (ja) 2011-03-31 2014-10-01 富士フイルム株式会社 シミュレーション方法、プログラムおよびそれを記録した記録媒体、並びに、それらを利用した液滴配置パターンの作成方法、ナノインプリント方法、パターン化基板の製造方法およびインクジェット装置。
CN103946374A (zh) 2011-09-12 2014-07-23 奥加诺沃公司 用于体外研究用途的工程化组织、其阵列及其制备方法
JP2014526318A (ja) 2011-09-12 2014-10-06 オルガノボ，インク． 操作した移植可能な組織および臓器のためのプラットフォームおよびそれを製造する方法
US10059056B2 (en) 2012-02-01 2018-08-28 Nscrypt, Inc. Micro-dispensing multi-layered 3D objects with curing steps
US10072257B2 (en) 2012-02-29 2018-09-11 Massachusetts Institute Of Technology Inverse patterning process for three-dimensional multi-compartmental micro-organization of multiple cell types
EP2822612A4 (en) 2012-03-06 2015-08-12 Uab Research Foundation THREE-DIMENSIONAL PREVASCULARIZED TREATED TISSUE CONSTRUCTS, METHOD OF MANUFACTURING AND METHOD OF USE OF THE TISSUE CONSTRUCTS
US9499779B2 (en) 2012-04-20 2016-11-22 Organovo, Inc. Devices, systems, and methods for the fabrication of tissue utilizing UV cross-linking
US20140099709A1 (en) 2012-06-19 2014-04-10 Organovo, Inc. Engineered three-dimensional connective tissue constructs and methods of making the same
EP2679669A1 (en) 2012-06-26 2014-01-01 ETH Zurich Fabrication of three-dimensional hydrogel objects
WO2014025953A2 (en) 2012-08-08 2014-02-13 Makerbot Industries, Llc Printed circuit board with integrated temperature sensing
US20140265046A1 (en) 2013-03-15 2014-09-18 Matterfab Corp. Laser sintering apparatus and methods
US9442105B2 (en) 2013-03-15 2016-09-13 Organovo, Inc. Engineered liver tissues, arrays thereof, and methods of making the same
US9802360B2 (en) 2013-06-04 2017-10-31 Stratsys, Inc. Platen planarizing process for additive manufacturing system
EP3028042B1 (en) 2013-07-31 2021-06-30 Organovo, Inc. Automated devices, systems, and methods for the fabrication of tissue
US11903612B2 (en) 2013-11-04 2024-02-20 University Of Iowa Research Foundation Bioprinter and methods of using same
CN106163581B (zh) 2013-11-05 2019-10-25 哈佛学院院长及董事 打印具有包埋的脉管系统的组织构建体的方法
CN106536720B (zh) 2014-04-04 2021-04-30 奥加诺沃公司 工程化的三维乳腺组织，脂肪组织和肿瘤疾病模型
JP2017529877A (ja) 2014-10-06 2017-10-12 オルガノボ インコーポレイテッド 人工の腎臓組織、そのアレイ、およびその作製方法
JP2017537654A (ja) 2014-11-05 2017-12-21 オルガノボ インコーポレイテッド 人工三次元皮膚組織、そのアレイ、およびその製造方法

Also Published As

Publication number Publication date
JP7007267B2 (ja) 2022-01-24
AU2016352873A1 (en) 2018-05-24
US12037603B2 (en) 2024-07-16
AU2016352873B2 (en) 2023-01-05
WO2017083402A1 (en) 2017-05-18
JP2018532418A (ja) 2018-11-08
EP3374495B1 (en) 2023-02-15
US20220195380A1 (en) 2022-06-23
EP3374495A4 (en) 2019-04-17
EP3374495A1 (en) 2018-09-19

Similar Documents

Publication Publication Date Title
HK1247835A1 (zh) 甲狀旁腺功能減退症的治療
HUE047477T2 (hu) Palbociclib szilárd dózisformái
DK3283511T3 (da) Modified collagen, methods of manufacture thereof
PL3288581T3 (pl) Sposób leczenia nowotworu
PL3283527T3 (pl) Leczenie skojarzone nowotworów
DK3212233T3 (da) Kombinationsterapi til behandling af sygdom
DK3192902T3 (da) Fremgangsmåde til fremstilling af graphenholdige viscosefibre
DK3134530T3 (da) Behandling af hyperbilirubinæmi
DK3240612T3 (da) Fremgangsmåder til behandling af nethindesygdomme
HUE056287T2 (hu) Pancreatitis kezelése
HK1252037A1 (zh) 治療炎性疾病的方法
EP3395011A4 (en) TELEMETRIE ADAPTATION
DK3374495T3 (da) Forbedrede fremgangsmåder til vævsfremstilling
DK3132009T3 (da) Fremgangsmåde
PL3393468T3 (pl) Metody leczenia niedoboru odporności
DK3283210T3 (da) Fremgangsmåde
EP3406336A4 (en) NANO FOIL OF CORE CASE STRUCTURE TYPE
EP3356516A4 (en) CULTIVATION OF HUMAN NOROVIRES
IL257764B (en) Methods for treatment of diseases
LT3119384T (lt) Intrahepatinių cholestazinių ligų gydymas
DK3164394T3 (da) Gls1-inhibitorer til behandling af sygdomme
IL272851A (en) Methods of using dipivefrin
DK3346990T3 (da) Fremgangsmåde til stråleformaling
DK3137449T3 (da) Fremgangsmåder til fremstilling af substituerede cycloseriner
DK3297619T3 (da) Terapeutiske anvendelser af L-4-chlorkynurenin