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DK3317400T3 - Fremgangsmåde til kryokonservering af tumorinfiltrerende lymfocytter - Google Patents

Fremgangsmåde til kryokonservering af tumorinfiltrerende lymfocytter Download PDF

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Publication number
DK3317400T3
DK3317400T3 DK16742353.2T DK16742353T DK3317400T3 DK 3317400 T3 DK3317400 T3 DK 3317400T3 DK 16742353 T DK16742353 T DK 16742353T DK 3317400 T3 DK3317400 T3 DK 3317400T3
Authority
DK
Denmark
Prior art keywords
lympocyts
infilrating
cryo
preservation
tumor
Prior art date
Application number
DK16742353.2T
Other languages
English (en)
Inventor
Larichaudy Joffrey De
Original Assignee
Chu Nantes
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chu Nantes filed Critical Chu Nantes
Application granted granted Critical
Publication of DK3317400T3 publication Critical patent/DK3317400T3/da

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Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10Preservation of living parts
    • A01N1/12Chemical aspects of preservation
    • A01N1/122Preservation or perfusion media
    • A01N1/125Freeze protecting agents, e.g. cryoprotectants or osmolarity regulators
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10Preservation of living parts
    • A01N1/12Chemical aspects of preservation
    • A01N1/122Preservation or perfusion media
    • A01N1/126Physiologically active agents, e.g. antioxidants or nutrients
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0636T lymphocytes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK16742353.2T 2015-06-30 2016-06-30 Fremgangsmåde til kryokonservering af tumorinfiltrerende lymfocytter DK3317400T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1556164A FR3040396A1 (fr) 2015-06-30 2015-06-30 Procede de cryoconservation de lymphocytes infiltrant la tumeur
PCT/FR2016/051631 WO2017001784A1 (fr) 2015-06-30 2016-06-30 Procédé de cryoconservation de lymphocytes infiltrant la tumeur

Publications (1)

Publication Number Publication Date
DK3317400T3 true DK3317400T3 (da) 2021-01-18

Family

ID=54066083

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16742353.2T DK3317400T3 (da) 2015-06-30 2016-06-30 Fremgangsmåde til kryokonservering af tumorinfiltrerende lymfocytter

Country Status (9)

Country Link
US (1) US20180187150A1 (da)
EP (1) EP3317400B1 (da)
JP (1) JP6876004B2 (da)
CN (1) CN108040460A (da)
CA (1) CA2990352A1 (da)
DK (1) DK3317400T3 (da)
ES (1) ES2839882T3 (da)
FR (1) FR3040396A1 (da)
WO (1) WO2017001784A1 (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3038324B1 (fr) * 2015-06-30 2020-10-30 Lab Francais Du Fractionnement Procede de cryoconservation de cellules a visee therapeutique
KR20240150531A (ko) 2016-10-26 2024-10-15 이오반스 바이오테라퓨틱스, 인크. 냉동보존된 종양 침윤 림프구의 재자극
TWI788307B (zh) 2016-10-31 2023-01-01 美商艾歐凡斯生物治療公司 用於擴增腫瘤浸潤性淋巴細胞之工程化人造抗原呈現細胞
WO2018094167A1 (en) 2016-11-17 2018-05-24 Iovance Biotherapeutics, Inc. Remnant tumor infiltrating lymphocytes and methods of preparing and using the same
EP3565586B1 (en) 2017-01-06 2025-10-08 Iovance Biotherapeutics, Inc. Expansion of tumor infiltrating lymphocytes with potassium channel agonists and therapeutic uses thereof
US11254913B1 (en) 2017-03-29 2022-02-22 Iovance Biotherapeutics, Inc. Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
JOP20190224A1 (ar) 2017-03-29 2019-09-26 Iovance Biotherapeutics Inc عمليات من أجل إنتاج الخلايا اللمفاوية المرتشحة للأورام واستخداماتها في العلاج المناعي
WO2018226714A1 (en) 2017-06-05 2018-12-13 Iovance Biotherapeutics, Inc. Methods of using tumor infiltrating lymphocytes in double-refractory melanoma
US11713446B2 (en) 2018-01-08 2023-08-01 Iovance Biotherapeutics, Inc. Processes for generating TIL products enriched for tumor antigen-specific T-cells
SG11202006541UA (en) 2018-01-08 2020-08-28 Iovance Biotherapeutics Inc Processes for generating til products enriched for tumor antigen-specific t-cells
EA202092319A1 (ru) * 2018-03-29 2021-03-04 Айовэнс Байотерапьютикс, Инк. Способы получения опухоль-инфильтрирующих лимфоцитов и применения их в иммунотерапии
US20210130779A1 (en) 2018-04-27 2021-05-06 Iovance Biotherapeutics, Inc. Closed process for expansion and gene editing of tumor infiltrating lymphocytes and uses of same in immunotherapy
WO2019217753A1 (en) 2018-05-10 2019-11-14 Iovance Biotherapeutics, Inc. Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
WO2020061429A1 (en) * 2018-09-20 2020-03-26 Iovance Biotherapeutics, Inc. Expansion of tils from cryopreserved tumor samples
CN113272421B (zh) 2018-11-05 2025-02-18 艾欧凡斯生物治疗公司 用于产生肿瘤浸润性淋巴细胞的方法及其在免疫疗法中的用途
FR3088541B1 (fr) * 2018-11-15 2021-11-05 Lab Francais Du Fractionnement Procede de conservation de cellules a visee therapeutique
IL297751A (en) 2020-04-28 2022-12-01 Lyell Immunopharma Inc Methods for culturing cells
US12453805B2 (en) 2020-09-24 2025-10-28 Everest Medical Innovation GmbH Cryoprotective compositions, surgical kits, and methods for protection of a surgical site during cryosurgery
US12426594B2 (en) 2020-09-24 2025-09-30 Everest Medical Innovation GmbH Cryoprotective compositions and methods for protection of a surgical site during cryosurgery
CN113632784A (zh) * 2021-08-10 2021-11-12 中国人民解放军海军军医大学 一种干细胞冻存保护剂及其使用方法
CN114073249B (zh) * 2021-10-29 2024-01-02 上海原天生物科技有限公司 一种人t淋巴细胞的慢速冻存方法
CA3248034A1 (en) 2022-04-15 2023-10-19 Iovance Biotherapeutics, Inc. METHODS FOR EXPANSION OF TIL CELLS BY MEANS OF SPECIFIC CYTOKINE COMBINATIONS AND/OR AKT INHIBITOR TREATMENT

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7489091A (en) * 1990-03-01 1991-09-18 Agouron Pharmaceuticals, Inc. Enhanced cryopreservation with thermal hysteresis peptide
CA2474968A1 (en) * 2002-01-31 2003-08-07 Asahi Techno Glass Corporation Cryopreservation medium for primate embryo stem cells and cryopreservation method
EP1569511A1 (en) * 2002-12-11 2005-09-07 CryoLife, Inc. Radical retardant cryopreservation solutions
JP4588598B2 (ja) * 2004-09-24 2010-12-01 セーレン株式会社 細胞凍結保存用組成物

Also Published As

Publication number Publication date
US20180187150A1 (en) 2018-07-05
WO2017001784A1 (fr) 2017-01-05
JP2018518965A (ja) 2018-07-19
FR3040396A1 (fr) 2017-03-03
EP3317400A1 (fr) 2018-05-09
EP3317400B1 (fr) 2020-10-28
CA2990352A1 (fr) 2017-01-05
CN108040460A (zh) 2018-05-15
ES2839882T3 (es) 2021-07-06
JP6876004B2 (ja) 2021-05-26

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