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DK32297A - Fremgangsmåde til fremstillingen af et mellemprodukt, som kan anvendes ved syntesen af ioderede kontrastmedier - Google Patents

Fremgangsmåde til fremstillingen af et mellemprodukt, som kan anvendes ved syntesen af ioderede kontrastmedier Download PDF

Info

Publication number
DK32297A
DK32297A DK032297A DK32297A DK32297A DK 32297 A DK32297 A DK 32297A DK 032297 A DK032297 A DK 032297A DK 32297 A DK32297 A DK 32297A DK 32297 A DK32297 A DK 32297A
Authority
DK
Denmark
Prior art keywords
synthesis
preparation
contrast media
iodinated contrast
iodinated
Prior art date
Application number
DK032297A
Other languages
Danish (da)
English (en)
Inventor
Marco Villa
Antonio Nardi
Maurizio Paiocchi
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Spa filed Critical Zambon Spa
Publication of DK32297A publication Critical patent/DK32297A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/02Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/46Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)
DK032297A 1996-03-29 1997-03-21 Fremgangsmåde til fremstillingen af et mellemprodukt, som kan anvendes ved syntesen af ioderede kontrastmedier DK32297A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT96MI000621A IT1283319B1 (it) 1996-03-29 1996-03-29 Processo per la preparazione di un intermedio utile nella sintesi di mezzi di contrasto iodurati

Publications (1)

Publication Number Publication Date
DK32297A true DK32297A (da) 1997-09-30

Family

ID=11373817

Family Applications (1)

Application Number Title Priority Date Filing Date
DK032297A DK32297A (da) 1996-03-29 1997-03-21 Fremgangsmåde til fremstillingen af et mellemprodukt, som kan anvendes ved syntesen af ioderede kontrastmedier

Country Status (21)

Country Link
US (1) US5817861A (no)
JP (1) JP4035198B2 (no)
BE (1) BE1010961A3 (no)
CA (1) CA2201012C (no)
CH (1) CH692044A5 (no)
CZ (1) CZ96097A3 (no)
DE (1) DE19713456B4 (no)
DK (1) DK32297A (no)
ES (1) ES2136011B1 (no)
FI (1) FI971318L (no)
FR (1) FR2746796B1 (no)
GB (1) GB2311524B (no)
HU (1) HU225647B1 (no)
IE (1) IE970214A1 (no)
IL (1) IL120483A (no)
IT (1) IT1283319B1 (no)
NL (1) NL1005650C2 (no)
NO (1) NO322508B1 (no)
PT (1) PT101982B (no)
SE (1) SE9701145L (no)
ZA (1) ZA972627B (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6262303B1 (en) 1998-05-08 2001-07-17 Dibra S.P.A. Process for the preparation of S-N,N′-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[(2-hydroxy-1-oxopropyl)-amino]-2,4,6-triiodo-1,3-benzenedicarboxamide
IT1299202B1 (it) * 1998-05-08 2000-02-29 Dibra Spa Processo per la preparazione della s-n,n'-bis (2-idrossi-1- (idrossimetil)etil) -5-((2-idrossi-1-ossopropil)ammino)-2,4,6-triiodo
IT1302200B1 (it) * 1998-09-11 2000-07-31 Dibra Spa PROCESSO PER LA PREPARAZIONE DELLA S-N,N'-BIS°2-IDROSSI-1-(IDROSSIMETIL)ETILé-5-°(2-IDROSSI-1-
KR20000075115A (ko) * 1999-05-28 2000-12-15 강재헌 불순물 c가 제거된 이오파미돌의 신규 제조방법
SI2365963T1 (sl) * 2008-11-18 2017-11-30 Bracco Imaging S.P.A. Postopek priprave jodiranih kontrastnih sredstev
CN105272899B (zh) * 2015-11-17 2017-09-22 浙江海洲制药有限公司 一种化合物及其用于合成碘帕醇杂质d、杂质f、杂质g和杂质j的方法
WO2019160037A1 (ja) * 2018-02-14 2019-08-22 国立大学法人 東京大学 酸ハロゲン化物による化合物の製造方法
CN116063195A (zh) * 2023-01-07 2023-05-05 安庆朗坤药业有限公司 一种碘帕醇中间体碘化物的制备方法
WO2024256322A1 (en) 2023-06-13 2024-12-19 Bracco Imaging Spa Synthesis of non-ionic radiographic contrast agents by means of reactive extrusion

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH608189A5 (no) * 1974-12-13 1978-12-29 Savac Ag
CH616403A5 (en) * 1975-10-29 1980-03-31 Bracco Ind Chimica Spa Process for the preparation of 2,4,6-triodoisophthalamides which are readily soluble in water.
FR2656865B1 (fr) * 1990-01-05 1993-03-26 Guerbet Sa Compose non ionique iode, son procede de preparation et produit de contraste le contenant.
ES2017277A6 (es) * 1989-09-20 1991-01-16 Juste Sa Un procedimiento para la preparacion de nuevos agentes iodados no ionicos de contraste.
IT1248741B (it) * 1991-02-26 1995-01-26 Bracco Spa Processo di concentrazione e di purificazione di composti organici
IT1256163B (it) * 1992-10-27 1995-11-29 Zambon Spa Processo per la preparazione di un intermedio della sintesi organica
DE4320499A1 (de) * 1993-05-14 1994-11-17 Bayer Ag Verfahren zur Herstellung von 2-Oximinoessigsäurederivaten
IT1274027B (it) * 1994-03-03 1997-07-14 Zambon Spa Processo per la preparazione e purificazione di mezzi di contrasto iodurati

Also Published As

Publication number Publication date
ITMI960621A1 (it) 1997-09-29
JP4035198B2 (ja) 2008-01-16
DE19713456A1 (de) 1997-10-30
NO971426D0 (no) 1997-03-25
FR2746796B1 (fr) 1998-09-11
GB2311524A (en) 1997-10-01
IL120483A (en) 2000-07-16
GB2311524B (en) 1999-04-07
SE9701145L (sv) 1997-09-30
FI971318A0 (fi) 1997-03-27
ITMI960621A0 (no) 1996-03-29
CZ96097A3 (cs) 1998-04-15
ZA972627B (en) 1997-10-23
BE1010961A3 (fr) 1999-03-02
NO971426L (no) 1997-09-30
HU225647B1 (en) 2007-05-29
CH692044A5 (it) 2002-01-15
FR2746796A1 (fr) 1997-10-03
HUP9700667A2 (hu) 1999-06-28
FI971318L (fi) 1997-09-30
US5817861A (en) 1998-10-06
PT101982B (pt) 1999-06-30
CA2201012A1 (en) 1997-09-29
IE970214A1 (en) 1997-10-08
IT1283319B1 (it) 1998-04-16
HU9700667D0 (en) 1997-05-28
NO322508B1 (no) 2006-10-16
ES2136011A1 (es) 1999-11-01
JPH107636A (ja) 1998-01-13
GB9706095D0 (en) 1997-05-14
ES2136011B1 (es) 2000-07-01
HUP9700667A3 (en) 2001-12-28
PT101982A (pt) 1997-11-28
NL1005650C2 (nl) 2000-05-31
IL120483A0 (en) 1997-07-13
CA2201012C (en) 2005-07-12
DE19713456B4 (de) 2007-01-11
NL1005650A1 (nl) 1997-09-30
SE9701145D0 (sv) 1997-03-27

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment