DK3137494T3 - Isletamyloidpolypeptider med forbedret opløselighed - Google Patents
Isletamyloidpolypeptider med forbedret opløselighed Download PDFInfo
- Publication number
- DK3137494T3 DK3137494T3 DK15786103.0T DK15786103T DK3137494T3 DK 3137494 T3 DK3137494 T3 DK 3137494T3 DK 15786103 T DK15786103 T DK 15786103T DK 3137494 T3 DK3137494 T3 DK 3137494T3
- Authority
- DK
- Denmark
- Prior art keywords
- isletamyloid
- polypeptides
- improved solubility
- solubility
- improved
- Prior art date
Links
- 102000036770 Islet Amyloid Polypeptide Human genes 0.000 title 1
- 108010041872 Islet Amyloid Polypeptide Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Endocrinology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Toxicology (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201461987723P | 2014-05-02 | 2014-05-02 | |
PCT/US2015/028683 WO2015168488A2 (en) | 2014-05-02 | 2015-05-01 | Islet amyloid polypeptides with improved solubility |
Publications (1)
Publication Number | Publication Date |
---|---|
DK3137494T3 true DK3137494T3 (da) | 2021-10-04 |
Family
ID=54359496
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK15786103.0T DK3137494T3 (da) | 2014-05-02 | 2015-05-01 | Isletamyloidpolypeptider med forbedret opløselighed |
Country Status (5)
Country | Link |
---|---|
US (2) | US10072060B2 (da) |
EP (1) | EP3137494B1 (da) |
CA (1) | CA2947587C (da) |
DK (1) | DK3137494T3 (da) |
WO (1) | WO2015168488A2 (da) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2015168488A2 (en) | 2014-05-02 | 2015-11-05 | The Research Foundation For The State University Of New York | Islet amyloid polypeptides with improved solubility |
AU2016232218B2 (en) | 2015-03-18 | 2020-09-10 | Boehringer Ingelheim International Gmbh | Amylin analogues |
TWI784968B (zh) | 2016-09-09 | 2022-12-01 | 丹麥商西蘭製藥公司 | 澱粉素類似物 |
US11028137B2 (en) | 2017-02-01 | 2021-06-08 | The Research Foundation For The State University Of New York | Mutant islet amyloid polypeptides with improved solubility and methods for using the same |
TW202400632A (zh) * | 2021-03-03 | 2024-01-01 | 美商美國禮來大藥廠 | 長效澱粉素受體促效劑及其用途 |
US12116388B2 (en) | 2022-12-22 | 2024-10-15 | Novo Nordisk A/S | Amylin receptor agonists |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK0567626T3 (da) | 1991-11-19 | 2001-12-17 | Amylin Pharmaceuticals Inc | Amylin-agonist-peptider og anvendelse deraf |
JP4353544B2 (ja) | 1998-01-09 | 2009-10-28 | アミリン・ファーマシューティカルズ,インコーポレイテッド | アミリン作動薬ペプチド用製剤 |
US20080248999A1 (en) * | 2007-04-04 | 2008-10-09 | Biodel Inc. | Amylin formulations |
DE102004051014A1 (de) * | 2004-10-20 | 2006-04-27 | Rwth Aachen | Chemisch modifizierte Peptidanaloga |
NZ593833A (en) * | 2009-02-03 | 2013-10-25 | Amunix Operating Inc | Extended recombinant polypeptides and compositions comprising same |
ES2705249T3 (es) * | 2009-06-08 | 2019-03-22 | Amunix Operating Inc | Polipéptidos reguladores de glucosa y métodos para su producción y uso |
US9814761B2 (en) * | 2012-04-03 | 2017-11-14 | Trustees Of Boston University | Compositions, methods and assays comprising amylin or amlyin analogs for abeta-peptide mediated disorders |
WO2015168488A2 (en) | 2014-05-02 | 2015-11-05 | The Research Foundation For The State University Of New York | Islet amyloid polypeptides with improved solubility |
-
2015
- 2015-05-01 WO PCT/US2015/028683 patent/WO2015168488A2/en active Application Filing
- 2015-05-01 CA CA2947587A patent/CA2947587C/en active Active
- 2015-05-01 EP EP15786103.0A patent/EP3137494B1/en active Active
- 2015-05-01 US US15/308,138 patent/US10072060B2/en active Active
- 2015-05-01 DK DK15786103.0T patent/DK3137494T3/da active
-
2018
- 2018-07-11 US US16/032,328 patent/US10683333B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
EP3137494A4 (en) | 2017-10-11 |
US10072060B2 (en) | 2018-09-11 |
WO2015168488A3 (en) | 2016-03-17 |
US20180319860A1 (en) | 2018-11-08 |
US10683333B2 (en) | 2020-06-16 |
WO2015168488A2 (en) | 2015-11-05 |
US20170051032A1 (en) | 2017-02-23 |
CA2947587A1 (en) | 2015-11-05 |
CA2947587C (en) | 2022-10-18 |
EP3137494A2 (en) | 2017-03-08 |
EP3137494B1 (en) | 2021-08-04 |
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