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DK3137494T3 - Isletamyloidpolypeptider med forbedret opløselighed - Google Patents

Isletamyloidpolypeptider med forbedret opløselighed Download PDF

Info

Publication number
DK3137494T3
DK3137494T3 DK15786103.0T DK15786103T DK3137494T3 DK 3137494 T3 DK3137494 T3 DK 3137494T3 DK 15786103 T DK15786103 T DK 15786103T DK 3137494 T3 DK3137494 T3 DK 3137494T3
Authority
DK
Denmark
Prior art keywords
isletamyloid
polypeptides
improved solubility
solubility
improved
Prior art date
Application number
DK15786103.0T
Other languages
English (en)
Inventor
Daniel Raleigh
Hui Wang
Ping Cao
Andisheh Abedini
Original Assignee
Univ New York State Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ New York State Res Found filed Critical Univ New York State Res Found
Application granted granted Critical
Publication of DK3137494T3 publication Critical patent/DK3137494T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/28Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DK15786103.0T 2014-05-02 2015-05-01 Isletamyloidpolypeptider med forbedret opløselighed DK3137494T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461987723P 2014-05-02 2014-05-02
PCT/US2015/028683 WO2015168488A2 (en) 2014-05-02 2015-05-01 Islet amyloid polypeptides with improved solubility

Publications (1)

Publication Number Publication Date
DK3137494T3 true DK3137494T3 (da) 2021-10-04

Family

ID=54359496

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15786103.0T DK3137494T3 (da) 2014-05-02 2015-05-01 Isletamyloidpolypeptider med forbedret opløselighed

Country Status (5)

Country Link
US (2) US10072060B2 (da)
EP (1) EP3137494B1 (da)
CA (1) CA2947587C (da)
DK (1) DK3137494T3 (da)
WO (1) WO2015168488A2 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015168488A2 (en) 2014-05-02 2015-11-05 The Research Foundation For The State University Of New York Islet amyloid polypeptides with improved solubility
AU2016232218B2 (en) 2015-03-18 2020-09-10 Boehringer Ingelheim International Gmbh Amylin analogues
TWI784968B (zh) 2016-09-09 2022-12-01 丹麥商西蘭製藥公司 澱粉素類似物
US11028137B2 (en) 2017-02-01 2021-06-08 The Research Foundation For The State University Of New York Mutant islet amyloid polypeptides with improved solubility and methods for using the same
TW202400632A (zh) * 2021-03-03 2024-01-01 美商美國禮來大藥廠 長效澱粉素受體促效劑及其用途
US12116388B2 (en) 2022-12-22 2024-10-15 Novo Nordisk A/S Amylin receptor agonists

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0567626T3 (da) 1991-11-19 2001-12-17 Amylin Pharmaceuticals Inc Amylin-agonist-peptider og anvendelse deraf
JP4353544B2 (ja) 1998-01-09 2009-10-28 アミリン・ファーマシューティカルズ,インコーポレイテッド アミリン作動薬ペプチド用製剤
US20080248999A1 (en) * 2007-04-04 2008-10-09 Biodel Inc. Amylin formulations
DE102004051014A1 (de) * 2004-10-20 2006-04-27 Rwth Aachen Chemisch modifizierte Peptidanaloga
NZ593833A (en) * 2009-02-03 2013-10-25 Amunix Operating Inc Extended recombinant polypeptides and compositions comprising same
ES2705249T3 (es) * 2009-06-08 2019-03-22 Amunix Operating Inc Polipéptidos reguladores de glucosa y métodos para su producción y uso
US9814761B2 (en) * 2012-04-03 2017-11-14 Trustees Of Boston University Compositions, methods and assays comprising amylin or amlyin analogs for abeta-peptide mediated disorders
WO2015168488A2 (en) 2014-05-02 2015-11-05 The Research Foundation For The State University Of New York Islet amyloid polypeptides with improved solubility

Also Published As

Publication number Publication date
EP3137494A4 (en) 2017-10-11
US10072060B2 (en) 2018-09-11
WO2015168488A3 (en) 2016-03-17
US20180319860A1 (en) 2018-11-08
US10683333B2 (en) 2020-06-16
WO2015168488A2 (en) 2015-11-05
US20170051032A1 (en) 2017-02-23
CA2947587A1 (en) 2015-11-05
CA2947587C (en) 2022-10-18
EP3137494A2 (en) 2017-03-08
EP3137494B1 (en) 2021-08-04

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