DK2925293T3 - Topiske tetracyclinformuleringer, fremstilling og anvendelser deraf - Google Patents
Topiske tetracyclinformuleringer, fremstilling og anvendelser derafInfo
- Publication number
- DK2925293T3 DK2925293T3 DK13792728.1T DK13792728T DK2925293T3 DK 2925293 T3 DK2925293 T3 DK 2925293T3 DK 13792728 T DK13792728 T DK 13792728T DK 2925293 T3 DK2925293 T3 DK 2925293T3
- Authority
- DK
- Denmark
- Prior art keywords
- applications
- preparation
- tetracycline formulations
- topical tetracycline
- topical
- Prior art date
Links
- 239000004098 Tetracycline Substances 0.000 title 1
- 238000009472 formulation Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 229960002180 tetracycline Drugs 0.000 title 1
- 229930101283 tetracycline Natural products 0.000 title 1
- 235000019364 tetracycline Nutrition 0.000 title 1
- 150000003522 tetracyclines Chemical class 0.000 title 1
- 230000000699 topical effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/203—Retinoic acids ; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4436—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Ophthalmology & Optometry (AREA)
- Dispersion Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Oncology (AREA)
- Rheumatology (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PT106679A PT106679B (pt) | 2012-11-27 | 2012-11-27 | Formulações tópicas de tetraciclinas, sua preparação e usos |
PCT/GB2013/052939 WO2014083311A1 (en) | 2012-11-27 | 2013-11-08 | Tetracycline topical formulations, preparation and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2925293T3 true DK2925293T3 (da) | 2017-11-06 |
Family
ID=49620233
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK13792728.1T DK2925293T3 (da) | 2012-11-27 | 2013-11-08 | Topiske tetracyclinformuleringer, fremstilling og anvendelser deraf |
Country Status (21)
Country | Link |
---|---|
US (2) | US9592246B2 (da) |
EP (1) | EP2925293B1 (da) |
JP (1) | JP6444308B2 (da) |
KR (1) | KR102235922B1 (da) |
CN (1) | CN104902875B (da) |
AU (1) | AU2013350941B2 (da) |
BR (1) | BR112015012162B1 (da) |
CA (1) | CA2895395C (da) |
DK (1) | DK2925293T3 (da) |
ES (1) | ES2645449T3 (da) |
HU (1) | HUE034932T2 (da) |
IL (1) | IL239022B (da) |
MX (1) | MX355174B (da) |
NO (1) | NO2925293T3 (da) |
NZ (1) | NZ708824A (da) |
PL (1) | PL2925293T3 (da) |
PT (1) | PT106679B (da) |
RU (1) | RU2639591C2 (da) |
SG (1) | SG11201504145PA (da) |
WO (1) | WO2014083311A1 (da) |
ZA (1) | ZA201504369B (da) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL152486A0 (en) | 2002-10-25 | 2003-05-29 | Meir Eini | Alcohol-free cosmetic and pharmaceutical foam carrier |
US9668972B2 (en) | 2002-10-25 | 2017-06-06 | Foamix Pharmaceuticals Ltd. | Nonsteroidal immunomodulating kit and composition and uses thereof |
US20080138296A1 (en) | 2002-10-25 | 2008-06-12 | Foamix Ltd. | Foam prepared from nanoemulsions and uses |
US7704518B2 (en) | 2003-08-04 | 2010-04-27 | Foamix, Ltd. | Foamable vehicle and pharmaceutical compositions thereof |
US7700076B2 (en) | 2002-10-25 | 2010-04-20 | Foamix, Ltd. | Penetrating pharmaceutical foam |
US9211259B2 (en) | 2002-11-29 | 2015-12-15 | Foamix Pharmaceuticals Ltd. | Antibiotic kit and composition and uses thereof |
US9265725B2 (en) | 2002-10-25 | 2016-02-23 | Foamix Pharmaceuticals Ltd. | Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof |
US10117812B2 (en) | 2002-10-25 | 2018-11-06 | Foamix Pharmaceuticals Ltd. | Foamable composition combining a polar solvent and a hydrophobic carrier |
NZ540166A (en) | 2002-10-25 | 2007-06-29 | Foamix Ltd | Cosmetic and pharmaceutical foam |
US20080260655A1 (en) | 2006-11-14 | 2008-10-23 | Dov Tamarkin | Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses |
US8636982B2 (en) | 2007-08-07 | 2014-01-28 | Foamix Ltd. | Wax foamable vehicle and pharmaceutical compositions thereof |
US9439857B2 (en) | 2007-11-30 | 2016-09-13 | Foamix Pharmaceuticals Ltd. | Foam containing benzoyl peroxide |
WO2009072007A2 (en) | 2007-12-07 | 2009-06-11 | Foamix Ltd. | Carriers, formulations, methods for formulating unstable active agents for external application and uses thereof |
WO2010125470A2 (en) | 2009-04-28 | 2010-11-04 | Foamix Ltd. | Foamable vehicle and pharmaceutical compositions comprising aprotic polar solvents and uses thereof |
WO2011013009A2 (en) | 2009-07-29 | 2011-02-03 | Foamix Ltd. | Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses |
CA2769677A1 (en) | 2009-07-29 | 2011-02-03 | Foamix Ltd. | Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses |
US9849142B2 (en) | 2009-10-02 | 2017-12-26 | Foamix Pharmaceuticals Ltd. | Methods for accelerated return of skin integrity and for the treatment of impetigo |
CA2776471C (en) | 2009-10-02 | 2019-02-12 | Foamix Ltd. | Surfactant-free, water-free, foamable compositions and breakable foams and their uses |
WO2016094876A1 (en) * | 2014-12-12 | 2016-06-16 | The Schepens Eye Research Institute, Inc. | Gdnf induction for the treatment of retinal disorders |
AU2016224863A1 (en) | 2015-02-25 | 2017-10-12 | Sun Pharma Advanced Research Company Ltd | Nanoparticulate composition |
RU2017134566A (ru) | 2015-03-23 | 2019-04-05 | Байофармкс, Инк. | Фармацевтическая тетрациклиновая композиция для дерматологического применения |
CN105380900B (zh) * | 2015-11-25 | 2018-05-29 | 徐州医学院 | 一种治疗痤疮的纳米磁疗外用凝胶及其制备方法和应用 |
MX377365B (es) | 2016-09-08 | 2025-03-10 | Journey Medical Corp | Composiciones y métodos para tratar rosácea y acné. |
FR3064482B1 (fr) * | 2017-04-03 | 2020-11-13 | Horus Pharma | Composition topique de doxycycline |
CA3078783A1 (en) * | 2017-10-24 | 2019-05-02 | Glenmark Pharmaceuticals Limited | Topical pharmaceutical composition of adapalene and minocycline |
US11421207B2 (en) | 2017-11-28 | 2022-08-23 | C-Lecta Gmbh | Method for producing trehalose employing a trehalose phosphorylase variant |
MX2020007222A (es) | 2018-01-07 | 2020-12-10 | Dr Reddys Laboratories Ltd | Metodos para el tratamiento de afecciones inflamatorias de la piel. |
US11202788B2 (en) | 2019-08-22 | 2021-12-21 | Nanopharmaceutics, Inc. | Topical doxycycline hydrogel with improved long-term stability |
WO2021191273A1 (en) | 2020-03-24 | 2021-09-30 | Hovione Scientia Limited | Compositions for use in treating meibomian gland dysfunction |
US20220062308A1 (en) | 2020-08-27 | 2022-03-03 | Hovione Scientia Limited | Methods and compositions for treating rosacea |
US20220125829A1 (en) * | 2020-10-28 | 2022-04-28 | Hovione Scientia Limited | Methods and compositions for treating meibomian gland dysfunction, dry eye disease, and related disorders |
CN115463091B (zh) * | 2022-10-27 | 2023-04-07 | 新基元(北京)医药科技有限公司 | 一种改善稳定性的米诺环素泡沫剂 |
Family Cites Families (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB769274A (en) * | 1954-04-22 | 1957-03-06 | Pfizer | Therapeutic preparations of tetracycline antibiotics in oil |
GB1581335A (en) | 1976-07-05 | 1980-12-10 | Leo Pharm Prod Ltd | 16-s-acyl derivatives of fusidic acid |
US4505896A (en) | 1979-04-19 | 1985-03-19 | Elorac, Ltd. | Method of treating acne vulgaris and composition |
JPS5788115A (en) * | 1980-10-06 | 1982-06-01 | Miles Lab | Stable non-aqueous solution of tetracycline antibiotic salt |
US5122519A (en) | 1989-06-27 | 1992-06-16 | American Cyanamid Company | Stable, cosmetically acceptable topical gel formulation and method of treatment for acne |
US5874479A (en) | 1991-03-01 | 1999-02-23 | Warner-Lambert Company | Therapeutic permeation enhanced-wound healing compositions and methods for preparing and using same |
US6113921A (en) | 1993-03-23 | 2000-09-05 | Pharmos Corp. | Topical and transdermal delivery system utilizing submicron oil spheres |
US5905092A (en) | 1994-09-27 | 1999-05-18 | Virotex Corporation Reel/Frame | Topical antibiotic composition providing optimal moisture environment for rapid wound healing that reduces skin contraction |
US5747058A (en) | 1995-06-07 | 1998-05-05 | Southern Biosystems, Inc. | High viscosity liquid controlled delivery system |
PT884997E (pt) * | 1996-02-16 | 2002-11-29 | Janssen Pharmaceutica Nv | Composicoes contendo um fungicida e um composto sulfurado |
JPH09255578A (ja) * | 1996-03-22 | 1997-09-30 | Sekisui Chem Co Ltd | 感染性皮膚疾患治療用外用剤 |
US5834008A (en) | 1996-09-19 | 1998-11-10 | U.S. Biomaterials Corp. | Composition and method for acceleration of wound and burn healing |
US6433068B1 (en) * | 1997-03-07 | 2002-08-13 | David S. Morrison | Hydrocarbon gels as suspending and dispersing agents and products |
EP1075265B1 (en) * | 1998-05-08 | 2006-03-08 | The University Of Miami | Use of tetracyclines for treating meibomian gland disease |
US20030007939A1 (en) | 1998-07-31 | 2003-01-09 | Howard Murad | Pharmaceutical compositions and methods for managing dermatological conditions |
US6432934B1 (en) * | 1998-08-06 | 2002-08-13 | Advanced Vision Research | Methods and compositions for topical treatment of eye surface inflammation and related dry eye disease |
KR20010075053A (ko) * | 1999-07-12 | 2001-08-09 | 도리이 신이찌로 | 국소 투여용 의약 조성물 |
US6946118B1 (en) | 1999-09-14 | 2005-09-20 | Orapharma, Inc. | Formulations for treating or preventing mucositis |
US6667045B2 (en) | 1999-10-01 | 2003-12-23 | Joseph Scott Dahle | Topical applications for skin treatment |
US20030077301A1 (en) | 1999-12-16 | 2003-04-24 | Maibach Howard I. | Topical pharmaceutical composition for the treatment of inflammatory dermatoses |
US6967023B1 (en) | 2000-01-10 | 2005-11-22 | Foamix, Ltd. | Pharmaceutical and cosmetic carrier or composition for topical application |
US20020010162A1 (en) | 2000-03-02 | 2002-01-24 | Raul Fleischmajer | Treatment of psoriasis with matrix metalloproteinase inhibitors |
US7758888B2 (en) | 2000-04-21 | 2010-07-20 | Sol-Gel Technologies Ltd. | Composition exhibiting enhanced formulation stability and delivery of topical active ingredients |
JP4653282B2 (ja) * | 2000-05-23 | 2011-03-16 | 昭和薬品化工株式会社 | ミノサイクリン含有組成物 |
US8512718B2 (en) | 2000-07-03 | 2013-08-20 | Foamix Ltd. | Pharmaceutical composition for topical application |
EP2311440A1 (en) * | 2001-04-05 | 2011-04-20 | Collagenex Pharmaceuticals, Inc. | Controlled delivery of tetracycline compounds and tetracycline derivatives |
CN1547475B (zh) | 2001-07-27 | 2010-12-15 | 生命健康科学有限公司 | 含电子转移试剂的磷酸酯衍生物的皮肤制剂 |
JP4723857B2 (ja) | 2002-06-17 | 2011-07-13 | ヴィキュロン ファーマシューティカルズ インコーポレイテッド | アクネの治療のためのge2270因子a3のアミド誘導体の使用 |
US20040076699A1 (en) * | 2002-07-15 | 2004-04-22 | Chaudhuri Ratan K. | Topical anhydrous delivery system |
US7820145B2 (en) | 2003-08-04 | 2010-10-26 | Foamix Ltd. | Oleaginous pharmaceutical and cosmetic foam |
US7700076B2 (en) | 2002-10-25 | 2010-04-20 | Foamix, Ltd. | Penetrating pharmaceutical foam |
US7704518B2 (en) * | 2003-08-04 | 2010-04-27 | Foamix, Ltd. | Foamable vehicle and pharmaceutical compositions thereof |
US7575739B2 (en) | 2003-04-28 | 2009-08-18 | Foamix Ltd. | Foamable iodine composition |
JP4223531B2 (ja) | 2003-06-11 | 2009-02-12 | ザ プロクター アンド ギャンブル カンパニー | 予備成形ヒドロゲル製品を含む使用時調製デバイス |
US8486374B2 (en) | 2003-08-04 | 2013-07-16 | Foamix Ltd. | Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses |
US7241746B2 (en) | 2003-08-06 | 2007-07-10 | Regena Therapeutics, Lc | Method and composition for treating periodontal disease |
EP1791791B1 (en) | 2004-09-27 | 2019-05-29 | Special Water Patents B.V. | Methods and compositions for treatment of water |
US7531164B2 (en) | 2005-10-21 | 2009-05-12 | Duke University | Preventing bacterial or viral infectivity and composition containing infection preventing additive |
GB2432529B (en) | 2005-11-25 | 2008-04-23 | Univ Feng Chia | Antimicrobial compositions and wound dressings |
JP4959991B2 (ja) * | 2006-03-03 | 2012-06-27 | 株式会社日本点眼薬研究所 | トラニラストまたはその薬理学的に許容される塩を含有する懸濁性医薬組成物 |
US20080188445A1 (en) | 2007-02-02 | 2008-08-07 | Warner Chilcott Company Inc. | Tetracycline compositions for topical administration |
US20080188446A1 (en) | 2007-02-02 | 2008-08-07 | Warner Chilcott Company Inc. | Tetracycline compositions for topical administration |
BRPI0808410A2 (pt) | 2007-02-28 | 2015-06-23 | Aciex Therapeutics Inc | Métodos e composições para normalizar secreções da glândula meibomiana |
JP5395052B2 (ja) * | 2007-03-23 | 2014-01-22 | モレキュラー リサーチ センター インコーポレイテッド | 炎症を処置するための組成物および方法 |
DE602008002692D1 (de) | 2007-07-25 | 2010-11-04 | Ixodes Gmbh | Topische antibiotische zusammensetzung zur prävention von lyme-borreliose |
WO2009072007A2 (en) | 2007-12-07 | 2009-06-11 | Foamix Ltd. | Carriers, formulations, methods for formulating unstable active agents for external application and uses thereof |
US8518376B2 (en) | 2007-12-07 | 2013-08-27 | Foamix Ltd. | Oil-based foamable carriers and formulations |
GB0800145D0 (en) * | 2008-01-04 | 2008-02-13 | Reckitt Benckiser Uk Ltd | Skincare treatment |
US20110092438A1 (en) * | 2008-03-28 | 2011-04-21 | Angesmg, Inc. | Composition for external application comprising transcription factor decoy as active ingredient |
EP2282714B1 (en) * | 2008-04-29 | 2017-12-13 | Hair Systems, Inc. | Composition and method for cream bleach product |
US20100029765A1 (en) | 2008-07-30 | 2010-02-04 | Ranbaxy Labortories Limited | Topical aqueous composition comprising tretinoin |
CA2734687A1 (en) * | 2008-08-18 | 2010-02-25 | Nanotherapeutics, Inc. | Topical hydrogel composition |
WO2010125470A2 (en) | 2009-04-28 | 2010-11-04 | Foamix Ltd. | Foamable vehicle and pharmaceutical compositions comprising aprotic polar solvents and uses thereof |
PT104644B (pt) | 2009-06-26 | 2012-11-06 | Hovione Farmaciencia S A | Formulação tópica contendo uma tetraciclina e método de tratamento de infecções cutâneas usando a mesma |
US9155915B2 (en) | 2009-07-27 | 2015-10-13 | Dermadoctor, Inc. | Moisturizing retinol composition |
GB2474930B (en) * | 2009-10-02 | 2012-07-04 | Foamix Ltd | Topical tetracycline compositions |
CA2776471C (en) | 2009-10-02 | 2019-02-12 | Foamix Ltd. | Surfactant-free, water-free, foamable compositions and breakable foams and their uses |
US9328162B2 (en) | 2010-02-25 | 2016-05-03 | Schepens Eye Research Institute | Therapeutic compositions for the treatment of dry eye disease |
US20120076766A1 (en) | 2010-04-21 | 2012-03-29 | Phillips D Howard | Topical drug delivery system with dual carriers |
US20130053353A1 (en) | 2010-05-04 | 2013-02-28 | Foamix Ltd. | Compositions, gels and foams with rheology modulators and uses |
PT105116B (pt) | 2010-05-14 | 2012-10-16 | Hovione Farmaciencia S A | Novas partículas de tetraciclina e agente protector. |
BRPI1002601E2 (pt) | 2010-06-01 | 2020-06-30 | Embrapa Pesquisa Agropecuaria | composição nanoestruturada de uso veterinário para administração de fármacos |
US20120093876A1 (en) | 2010-10-13 | 2012-04-19 | Aciex, Inc. | Ophthalmic Formulations, Methods Of Manufacture And Methods of Normalizing Meibomian Gland Secretions |
US8481591B2 (en) | 2010-11-01 | 2013-07-09 | Stiefel Research Australia Pty. Ltd. | Polymeric topical compositions |
EP2667945A1 (en) | 2011-01-24 | 2013-12-04 | Anterios, Inc. | Oil compositions |
-
2012
- 2012-11-27 PT PT106679A patent/PT106679B/pt active IP Right Grant
-
2013
- 2013-11-08 EP EP13792728.1A patent/EP2925293B1/en active Active
- 2013-11-08 NZ NZ708824A patent/NZ708824A/en not_active IP Right Cessation
- 2013-11-08 MX MX2015006632A patent/MX355174B/es active IP Right Grant
- 2013-11-08 ES ES13792728.1T patent/ES2645449T3/es active Active
- 2013-11-08 CA CA2895395A patent/CA2895395C/en active Active
- 2013-11-08 KR KR1020157017068A patent/KR102235922B1/ko active Active
- 2013-11-08 CN CN201380068453.1A patent/CN104902875B/zh active Active
- 2013-11-08 PL PL13792728T patent/PL2925293T3/pl unknown
- 2013-11-08 NO NO13792728A patent/NO2925293T3/no unknown
- 2013-11-08 RU RU2015122786A patent/RU2639591C2/ru active
- 2013-11-08 JP JP2015543515A patent/JP6444308B2/ja active Active
- 2013-11-08 WO PCT/GB2013/052939 patent/WO2014083311A1/en active Application Filing
- 2013-11-08 AU AU2013350941A patent/AU2013350941B2/en not_active Ceased
- 2013-11-08 SG SG11201504145PA patent/SG11201504145PA/en unknown
- 2013-11-08 HU HUE13792728A patent/HUE034932T2/en unknown
- 2013-11-08 BR BR112015012162-4A patent/BR112015012162B1/pt active IP Right Grant
- 2013-11-08 US US14/074,868 patent/US9592246B2/en active Active - Reinstated
- 2013-11-08 DK DK13792728.1T patent/DK2925293T3/da active
-
2015
- 2015-05-26 IL IL239022A patent/IL239022B/en active IP Right Grant
- 2015-06-17 ZA ZA2015/04369A patent/ZA201504369B/en unknown
-
2017
- 2017-03-13 US US15/457,809 patent/US10213443B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
KR102235922B1 (ko) | 2021-04-05 |
CA2895395C (en) | 2021-04-06 |
US20170182071A1 (en) | 2017-06-29 |
MX2015006632A (es) | 2016-02-17 |
US9592246B2 (en) | 2017-03-14 |
US10213443B2 (en) | 2019-02-26 |
EP2925293B1 (en) | 2017-08-02 |
PL2925293T3 (pl) | 2017-12-29 |
US20140147504A1 (en) | 2014-05-29 |
RU2015122786A (ru) | 2017-01-10 |
AU2013350941B2 (en) | 2018-04-26 |
RU2639591C2 (ru) | 2017-12-21 |
MX355174B (es) | 2018-04-09 |
IL239022A0 (en) | 2015-07-30 |
ES2645449T3 (es) | 2017-12-05 |
NZ708824A (en) | 2019-01-25 |
EP2925293A1 (en) | 2015-10-07 |
JP6444308B2 (ja) | 2018-12-26 |
IL239022B (en) | 2020-11-30 |
CN104902875A (zh) | 2015-09-09 |
SG11201504145PA (en) | 2015-07-30 |
PT106679B (pt) | 2015-03-25 |
AU2013350941A1 (en) | 2015-07-16 |
CA2895395A1 (en) | 2014-06-05 |
HUE034932T2 (en) | 2018-03-28 |
JP2016500095A (ja) | 2016-01-07 |
KR20150104102A (ko) | 2015-09-14 |
BR112015012162B1 (pt) | 2021-02-23 |
NO2925293T3 (da) | 2017-12-30 |
ZA201504369B (en) | 2017-01-25 |
WO2014083311A1 (en) | 2014-06-05 |
PT106679A (pt) | 2014-05-27 |
CN104902875B (zh) | 2018-04-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK2925293T3 (da) | Topiske tetracyclinformuleringer, fremstilling og anvendelser deraf | |
IL289759A (en) | Formulations for local disinfection and their uses | |
DK3216448T3 (da) | Paraciticide orale veterinære sammensætninger omfattende systemisk-virkende aktivstoffer, fremgangsmåder og anvendelser deraf | |
DK2888251T3 (da) | Perforinhæmmende benzensulfonamidforbindelser, fremstilling og anvendelser deraf | |
HK1209079A1 (zh) | 催化的劑型和配方 | |
DK2903600T3 (da) | Virusholdig formulering og anvendelse deraf | |
BR112015002738A2 (pt) | composto , e , composição farmacêutica | |
DK2648742T3 (da) | Formuleringer indeholdende saponiner og anvendelser deraf | |
SI3725778T1 (sl) | Formulacije enzalutamida | |
DK2841429T3 (da) | Tetrazolinonforbindelser og anvendelse deraf som pesticider | |
DK2729151T3 (da) | Farmaceutisk sammensætning, fremgangsmåder til behandling og anvendelser deraf | |
BR112014029403A2 (pt) | conjugados, anticorpo e formulação farmacêutica | |
DK3444268T3 (da) | Staphylococcus aureus-leukocidiner, terapeutiske sammensætninger og anvendelser deraf | |
HUE036755T2 (hu) | Antimikrobiális vegyületek, valamint ezek elõállítása és alkalmazása | |
EP2804606A4 (en) | TOPICAL THERAPEUTIC FORMULATIONS | |
DK2917181T3 (da) | Heteroarylderivater og anvendelser deraf | |
EP2887958A4 (en) | liposome | |
DK2809669T3 (da) | Kondenserede pyrroldicarboxamider og deres anvendelse som farmaceutika | |
HK1209636A1 (en) | Trans-clomiphene formulations and uses thereof (trans-clomiphene) | |
HUE036112T2 (hu) | Mikróbaellenes ionomer készítmény és alkalmazásaik | |
BR112014028280A2 (pt) | composições farmacêuticas tópicas compreendendo terbinafina e ureia | |
CY2200004T2 (el) | Σκευασματα δαπτομυκινης και χρησεις αυτων | |
DK3156060T3 (da) | Farmaceutiske sammensætninger og topisk anvendelse deraf | |
CL2014003283A1 (es) | Formulación farmacéutica. | |
DK2849798T3 (da) | Oligonukleotid-chelatkompleks-polypeptidsammensætninger og fremgangsmåder |