DK2805954T3 - 7-substitueret hanfangichin b-derivat, og fremstillingsfremgangsmåde og anvendelse deraf - Google Patents
7-substitueret hanfangichin b-derivat, og fremstillingsfremgangsmåde og anvendelse deraf Download PDFInfo
- Publication number
- DK2805954T3 DK2805954T3 DK13738800.5T DK13738800T DK2805954T3 DK 2805954 T3 DK2805954 T3 DK 2805954T3 DK 13738800 T DK13738800 T DK 13738800T DK 2805954 T3 DK2805954 T3 DK 2805954T3
- Authority
- DK
- Denmark
- Prior art keywords
- hanfangichin
- derivate
- substituted
- preparation
- application
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/18—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012070698 | 2012-01-21 | ||
| PCT/CN2013/070800 WO2013107428A1 (zh) | 2012-01-21 | 2013-01-21 | 7-位取代的汉防己乙素衍生物、及其制备方法和应用 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2805954T3 true DK2805954T3 (da) | 2019-09-23 |
Family
ID=48798682
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK13738800.5T DK2805954T3 (da) | 2012-01-21 | 2013-01-21 | 7-substitueret hanfangichin b-derivat, og fremstillingsfremgangsmåde og anvendelse deraf |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US9328122B2 (da) |
| EP (1) | EP2805954B1 (da) |
| JP (1) | JP6298768B2 (da) |
| DK (1) | DK2805954T3 (da) |
| WO (1) | WO2013107428A1 (da) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107207524B (zh) * | 2014-08-15 | 2020-02-07 | 贵州省中国科学院天然产物化学重点实验室 | 双苄基异喹啉衍生物、其制备方法及其在肝病的治疗与预防中的用途 |
| CN107033157B (zh) * | 2016-02-03 | 2020-05-05 | 贵州省中国科学院天然产物化学重点实验室 | 双苄基异喹啉衍生物及其在制备用于治疗或预防肿瘤的药物中的用途 |
| CN109776553B (zh) * | 2019-01-15 | 2020-05-29 | 山东师范大学 | 福己素及其制备方法和应用 |
| CN110156808B (zh) * | 2019-06-21 | 2022-01-18 | 华中农业大学 | 具有杀菌活性的防己诺林碱-氨基甲酸酯类衍生物 |
| CN112250690B (zh) * | 2020-09-24 | 2022-07-15 | 山东师范大学 | 磺酰基防己诺林碱类化合物及其制备方法和应用 |
| CN114031623B (zh) * | 2021-11-12 | 2023-04-11 | 山西医科大学 | 一种c14位氨基取代粉防己碱衍生物及其制备和应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0678232B2 (ja) * | 1986-03-07 | 1994-10-05 | 株式会社ツムラ | アンジオテンシンｉ転換酵素阻害剤 |
| JPH02134382A (ja) * | 1988-11-14 | 1990-05-23 | Kaken Shiyouyaku Kk | ビスベンジルイソキノリン誘導体 |
| JPH02243627A (ja) * | 1989-03-16 | 1990-09-27 | Tsumura & Co | 狭心症治療薬 |
| CN1111160C (zh) * | 2000-09-08 | 2003-06-11 | 成都康弘制药有限公司 | 双苄基异喹啉类生物碱和药物组合物及用途 |
| CN1511528A (zh) | 2002-12-30 | 2004-07-14 | 北京大学第一医院 | 防己诺林碱在抑制血管生成药物中的应用 |
| CN1511527A (zh) * | 2002-12-31 | 2004-07-14 | 北京大学第一医院 | 粉防已碱在抑制血管生成药物中的应用 |
| CN101371839B (zh) * | 2008-10-08 | 2010-11-03 | 中国科学院化学研究所 | 双苄基异喹啉类生物碱的新用途 |
-
2013
- 2013-01-21 EP EP13738800.5A patent/EP2805954B1/en active Active
- 2013-01-21 DK DK13738800.5T patent/DK2805954T3/da active
- 2013-01-21 US US14/373,526 patent/US9328122B2/en not_active Expired - Fee Related
- 2013-01-21 WO PCT/CN2013/070800 patent/WO2013107428A1/zh active Application Filing
- 2013-01-21 JP JP2014552508A patent/JP6298768B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2013107428A1 (zh) | 2013-07-25 |
| EP2805954B1 (en) | 2019-06-19 |
| EP2805954A4 (en) | 2015-10-21 |
| JP6298768B2 (ja) | 2018-03-20 |
| JP2015504075A (ja) | 2015-02-05 |
| US20140357647A1 (en) | 2014-12-04 |
| EP2805954A1 (en) | 2014-11-26 |
| US9328122B2 (en) | 2016-05-03 |
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