[go: up one dir, main page]

DK2649070T3 - Triazolpyridinforbindelser - Google Patents

Triazolpyridinforbindelser

Info

Publication number
DK2649070T3
DK2649070T3 DK11791543.9T DK11791543T DK2649070T3 DK 2649070 T3 DK2649070 T3 DK 2649070T3 DK 11791543 T DK11791543 T DK 11791543T DK 2649070 T3 DK2649070 T3 DK 2649070T3
Authority
DK
Denmark
Prior art keywords
triazolpyridine
compounds
triazolpyridine compounds
Prior art date
Application number
DK11791543.9T
Other languages
English (en)
Inventor
Alexander Flohr
Luca Gobbi
Zbinden Katrin Groebke
Matthias Koerner
Jens-Uwe Peters
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK2649070T3 publication Critical patent/DK2649070T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Hematology (AREA)
  • Psychology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Addiction (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK11791543.9T 2010-12-07 2011-12-05 Triazolpyridinforbindelser DK2649070T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP10194014 2010-12-07
PCT/EP2011/071685 WO2012076430A1 (en) 2010-12-07 2011-12-05 Triazolopyridine compounds

Publications (1)

Publication Number Publication Date
DK2649070T3 true DK2649070T3 (da) 2014-10-13

Family

ID=45099086

Family Applications (1)

Application Number Title Priority Date Filing Date
DK11791543.9T DK2649070T3 (da) 2010-12-07 2011-12-05 Triazolpyridinforbindelser

Country Status (31)

Country Link
US (1) US8349824B2 (da)
EP (1) EP2649070B1 (da)
JP (1) JP5932828B2 (da)
KR (1) KR20130128426A (da)
CN (1) CN103237803B (da)
AR (1) AR084152A1 (da)
AU (1) AU2011340685A1 (da)
BR (1) BR112013013912A2 (da)
CA (1) CA2816829C (da)
CL (1) CL2013001591A1 (da)
CO (1) CO6741154A2 (da)
CR (1) CR20130239A (da)
CY (1) CY1115863T1 (da)
DK (1) DK2649070T3 (da)
EA (1) EA022607B1 (da)
EC (1) ECSP13012667A (da)
ES (1) ES2520647T3 (da)
HR (1) HRP20141200T1 (da)
IL (1) IL225969A0 (da)
MA (1) MA35086B1 (da)
MX (1) MX2013006054A (da)
PE (1) PE20140226A1 (da)
PH (1) PH12013500942A1 (da)
PL (1) PL2649070T3 (da)
PT (1) PT2649070E (da)
RS (1) RS53677B1 (da)
SG (1) SG190305A1 (da)
SI (1) SI2649070T1 (da)
UA (1) UA109037C2 (da)
WO (1) WO2012076430A1 (da)
ZA (1) ZA201303811B (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013043518A1 (en) 2011-09-22 2013-03-28 Merck Sharp & Dohme Corp. Imidazopyridyl compounds as aldosterone synthase inhibitors
WO2013043520A1 (en) 2011-09-22 2013-03-28 Merck Sharp & Dohme Corp. Triazolopyridyl compounds as aldosterone synthase inhibitors
CA2858778A1 (en) 2012-02-09 2013-08-15 F. Hoffmann-La Roche Ag Process for the preparation of 2-phenyl-[1,2,4]triazolo[1,5-a]pyridine derivatives
CA2899781A1 (en) * 2013-01-31 2014-08-07 F.Hoffmann-La Roche Ag Radiolabeled compounds
AU2014221799B2 (en) 2013-02-27 2017-09-28 Mochida Pharmaceutical Co., Ltd. Novel pyrazole derivative
MY169128A (en) 2013-04-30 2019-02-18 Hoffmann La Roche Pd-catalyzed coupling of pyrazole amides
ES2651491T3 (es) * 2013-05-31 2018-01-26 Nissan Chemical Industries, Ltd. Compuesto de amida heterocíclico
WO2015006689A1 (en) 2013-07-12 2015-01-15 University Of South Alabama Treatment and diagnosis of cancer and precancerous conditions using pde10a inhibitors and methods to measure pde10a expression
WO2016017711A1 (ja) * 2014-07-30 2016-02-04 持田製薬株式会社 ピラゾール誘導体の製造方法
WO2016017719A1 (ja) * 2014-07-30 2016-02-04 持田製薬株式会社 ピラゾール誘導体の製造方法
JP6745594B2 (ja) * 2015-11-26 2020-08-26 持田製薬株式会社 ピラゾール誘導体の塩の結晶
WO2020021024A1 (en) * 2018-07-26 2020-01-30 Phenex Pharmaceuticals Ag Substituted bicyclic compounds as modulators of the aryl hydrocarbon receptor (ahr)
US12544364B2 (en) 2020-06-05 2026-02-10 Noema Pharma Ag Use of a phosphodiesterase 10 inhibitor for the treatment of tourette syndrome
MX2022015400A (es) 2020-06-05 2023-03-16 Noema Pharma Ag Uso del inhibidor de la fosfodiesterasa a 10 para el tratamiento del sindrome de tourette.
MX2023008796A (es) 2021-01-28 2023-10-10 Noema Pharma Ag Métodos para el tratamiento del trastorno del habla en niños.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070032404A1 (en) 2003-07-31 2007-02-08 Bayer Pharmaceuticals Corporation Methods for treating diabetes and related disorders using pde10a inhibitors
TWI501965B (zh) 2008-06-20 2015-10-01 Lundbeck & Co As H 作為pde10a酵素抑制劑之新穎苯基咪唑衍生物

Also Published As

Publication number Publication date
AU2011340685A1 (en) 2013-05-23
CN103237803A (zh) 2013-08-07
RS53677B1 (sr) 2015-04-30
US8349824B2 (en) 2013-01-08
EP2649070A1 (en) 2013-10-16
CA2816829C (en) 2018-12-04
SG190305A1 (en) 2013-06-28
CR20130239A (es) 2013-06-27
KR20130128426A (ko) 2013-11-26
HRP20141200T1 (hr) 2015-02-13
ECSP13012667A (es) 2013-08-30
EA201390799A1 (ru) 2013-12-30
CY1115863T1 (el) 2017-01-25
ZA201303811B (en) 2014-04-30
BR112013013912A2 (pt) 2016-09-13
MA35086B1 (fr) 2014-05-02
US20120142665A1 (en) 2012-06-07
UA109037C2 (uk) 2015-07-10
JP5932828B2 (ja) 2016-06-08
PH12013500942A1 (en) 2017-05-19
ES2520647T3 (es) 2014-11-11
WO2012076430A1 (en) 2012-06-14
CO6741154A2 (es) 2013-08-30
PE20140226A1 (es) 2014-03-08
AR084152A1 (es) 2013-04-24
PT2649070E (pt) 2014-11-21
SI2649070T1 (sl) 2014-12-31
IL225969A0 (en) 2013-06-27
EA022607B1 (ru) 2016-01-29
MX2013006054A (es) 2013-06-18
JP2013544859A (ja) 2013-12-19
CL2013001591A1 (es) 2013-12-27
EP2649070B1 (en) 2014-09-17
CN103237803B (zh) 2016-04-13
CA2816829A1 (en) 2012-06-14
PL2649070T3 (pl) 2015-03-31

Similar Documents

Publication Publication Date Title
BR112013009935C8 (pt) compostos
PL2614063T3 (pl) Podstawione imidazopirydazyny
DOP2012000224A (es) Compuesto heterociclico
DK3225404T3 (da) Fluidpatron
EP2578585A4 (en) Purinone derivative
BR112012028556A2 (pt) Indóis
DE102011100241A8 (de) Nitridhalbleiterbauteil
CR20130111A (es) Triazina-oxidiazoles
DK2648516T3 (da) Substituerede pyridinon-pyridinylforbindelser
DE10170954T8 (de) Mikrowellendruckgarer
EP2568873A4 (en) VACUUM RETRACTOR
EP2529782A4 (en) INTRODUCER SLEEVE ASSEMBLY
CO6801726A2 (es) Compuestos
EP2591235A4 (en) FUSION METAL WHEEL
DE112011104226A5 (de) Käfigmutter
PT2626350E (pt) Composto de ciclopropano
DK2649070T3 (da) Triazolpyridinforbindelser
DE102011117046A8 (de) Doppelkupplungswindungsgetriebe
DE112011101226A5 (de) Linearwegmesssystem
DE112011102080A5 (de) Kupplungszentralausrücker
DK2442899T3 (da) Rotorskive
DK2539163T3 (da) Dækventil
BR112012026803A2 (pt) composto
DE102010038420A8 (de) Reinigungungsvorrichtung
DE102011002623A8 (de) Ventilsteuerzeitversteller