DK2539465T3 - Analytsekventering med nanoporer - Google Patents
Analytsekventering med nanoporer Download PDFInfo
- Publication number
- DK2539465T3 DK2539465T3 DK11748022.8T DK11748022T DK2539465T3 DK 2539465 T3 DK2539465 T3 DK 2539465T3 DK 11748022 T DK11748022 T DK 11748022T DK 2539465 T3 DK2539465 T3 DK 2539465T3
- Authority
- DK
- Denmark
- Prior art keywords
- nanopores
- analyte
- sequencing
- analyte sequencing
- Prior art date
Links
- 239000012491 analyte Substances 0.000 title 1
- 238000012163 sequencing technique Methods 0.000 title 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44756—Apparatus specially adapted therefor
- G01N27/44791—Microapparatus
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- G—PHYSICS
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
- G01N33/48721—Investigating individual macromolecules, e.g. by translocation through nanopores
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
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- C—CHEMISTRY; METALLURGY
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Y10S977/924—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis using nanostructure as support of dna analysis
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- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Theoretical Computer Science (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Human Computer Interaction (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nanotechnology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Food Science & Technology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US30744110P | 2010-02-23 | 2010-02-23 | |
US37570710P | 2010-08-20 | 2010-08-20 | |
PCT/US2011/025963 WO2011106459A2 (en) | 2010-02-23 | 2011-02-23 | Analyte sequencing with nanopores |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2539465T3 true DK2539465T3 (da) | 2024-03-11 |
Family
ID=44507548
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK11748022.8T DK2539465T3 (da) | 2010-02-23 | 2011-02-23 | Analytsekventering med nanoporer |
DK11748021.0T DK2539707T3 (da) | 2010-02-23 | 2011-02-23 | Kunstige mycolsyremembraner |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK11748021.0T DK2539707T3 (da) | 2010-02-23 | 2011-02-23 | Kunstige mycolsyremembraner |
Country Status (8)
Country | Link |
---|---|
US (5) | US9588079B2 (da) |
EP (4) | EP3933402A1 (da) |
CN (2) | CN102834716B (da) |
CA (5) | CA2790666C (da) |
DK (2) | DK2539465T3 (da) |
ES (2) | ES2978883T3 (da) |
FI (1) | FI2539465T3 (da) |
WO (2) | WO2011106456A2 (da) |
Families Citing this family (74)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8889348B2 (en) | 2006-06-07 | 2014-11-18 | The Trustees Of Columbia University In The City Of New York | DNA sequencing by nanopore using modified nucleotides |
US9605307B2 (en) | 2010-02-08 | 2017-03-28 | Genia Technologies, Inc. | Systems and methods for forming a nanopore in a lipid bilayer |
US8324914B2 (en) | 2010-02-08 | 2012-12-04 | Genia Technologies, Inc. | Systems and methods for characterizing a molecule |
US9678055B2 (en) | 2010-02-08 | 2017-06-13 | Genia Technologies, Inc. | Methods for forming a nanopore in a lipid bilayer |
DK2539465T3 (da) | 2010-02-23 | 2024-03-11 | Univ Washington | Analytsekventering med nanoporer |
CN107083421A (zh) | 2010-12-17 | 2017-08-22 | 纽约哥伦比亚大学理事会 | 使用经修饰的核苷酸和纳米孔检测的dna边合成边测序 |
WO2012088339A2 (en) | 2010-12-22 | 2012-06-28 | Genia Technologies, Inc. | Nanopore-based single dna molecule characterization using speed bumps |
US8962242B2 (en) | 2011-01-24 | 2015-02-24 | Genia Technologies, Inc. | System for detecting electrical properties of a molecular complex |
US9110478B2 (en) | 2011-01-27 | 2015-08-18 | Genia Technologies, Inc. | Temperature regulation of measurement arrays |
BR112013030529B1 (pt) | 2011-05-27 | 2023-03-07 | Oxford Nanopore Technologies Plc | Método para determinar a presença, ausência ou características de um analito, método e aparelho para sequenciamento de um analito que é um polinucleotídeo alvo, e, kit |
EP2807476A4 (en) * | 2012-01-20 | 2015-12-09 | Genia Technologies Inc | MOLECULAR DETECTION AND SEQUENCING USING NANOPORES |
US8541849B2 (en) * | 2012-02-14 | 2013-09-24 | Genia Technologies, Inc. | Noise shielding techniques for ultra low current measurements in biochemical applications |
CA2866587C (en) | 2012-02-16 | 2022-07-26 | Oxford Nanopore Technologies Limited | Analysis of measurements of a polymer |
US8986629B2 (en) | 2012-02-27 | 2015-03-24 | Genia Technologies, Inc. | Sensor circuit for controlling, detecting, and measuring a molecular complex |
WO2013154999A2 (en) | 2012-04-09 | 2013-10-17 | The Trustees Of Columbia University In The City Of New York | Method of preparation of nanopore and uses thereof |
WO2013153359A1 (en) | 2012-04-10 | 2013-10-17 | Oxford Nanopore Technologies Limited | Mutant lysenin pores |
WO2013159042A1 (en) | 2012-04-19 | 2013-10-24 | University Of Washington Through Its Center For Commercialization | Methods and compositions for generating reference maps for nanopore-based polymer analysis |
CN104350162A (zh) | 2012-06-15 | 2015-02-11 | 吉尼亚科技公司 | 芯片设置和高精确度核酸测序 |
EP3511424B1 (en) | 2012-08-03 | 2023-10-18 | University Of Washington Through Its Center For Commercialization | Compositions and methods for improving nanopore sequencing |
CN102867851B (zh) * | 2012-09-07 | 2015-10-28 | 中国科学院苏州纳米技术与纳米仿生研究所 | 离子束流信号放大器及其制造方法 |
WO2014071250A1 (en) * | 2012-11-01 | 2014-05-08 | University Of Washington Through Its Center For Commercialization | Methods for detecting and mapping modifications to nucleic acid polymers using nanopore systems |
US9605309B2 (en) | 2012-11-09 | 2017-03-28 | Genia Technologies, Inc. | Nucleic acid sequencing using tags |
GB201222928D0 (en) | 2012-12-19 | 2013-01-30 | Oxford Nanopore Tech Ltd | Analysis of a polynucleotide |
US9759711B2 (en) | 2013-02-05 | 2017-09-12 | Genia Technologies, Inc. | Nanopore arrays |
WO2014130686A2 (en) * | 2013-02-20 | 2014-08-28 | Eve Biomedical, Inc. | Methods and compositions for nanostructure-based nucleic acid sequencing |
WO2014144898A1 (en) | 2013-03-15 | 2014-09-18 | The Trustees Of Columbia University In The City Of New York | Method for detecting multiple predetermined compounds in a sample |
WO2014144883A1 (en) | 2013-03-15 | 2014-09-18 | The Trustees Of Columbia University In The City Of New York | Raman cluster tagged molecules for biological imaging |
GB201313477D0 (en) | 2013-07-29 | 2013-09-11 | Univ Leuven Kath | Nanopore biosensors for detection of proteins and nucleic acids |
CA2921700A1 (en) | 2013-08-30 | 2015-03-05 | University Of Washington Through Its Center For Commercialization | Selective modification of polymer subunits to improve nanopore-based analysis |
WO2015051378A1 (en) * | 2013-10-04 | 2015-04-09 | University Of Washington Through Its Center For Commercialization | Systems and methods for nanopore-based analysis of nucleic acids |
US9551697B2 (en) | 2013-10-17 | 2017-01-24 | Genia Technologies, Inc. | Non-faradaic, capacitively coupled measurement in a nanopore cell array |
US9567630B2 (en) | 2013-10-23 | 2017-02-14 | Genia Technologies, Inc. | Methods for forming lipid bilayers on biochips |
EP3060918B1 (en) | 2013-10-23 | 2019-09-18 | Genia Technologies, Inc. | High speed molecular sensing with nanopores |
GB201406155D0 (en) | 2014-04-04 | 2014-05-21 | Oxford Nanopore Tech Ltd | Method |
JP6749243B2 (ja) | 2014-01-22 | 2020-09-02 | オックスフォード ナノポール テクノロジーズ リミテッド | 1つまたは複数のポリヌクレオチド結合タンパク質を標的ポリヌクレオチドに付着させる方法 |
SG10202111841TA (en) | 2014-02-19 | 2021-12-30 | Univ Washington | Nanopore-based analysis of protein characteristics |
WO2015127387A1 (en) * | 2014-02-21 | 2015-08-27 | Northeastern University | Fluorescence-based analysis of biopolymers using nanopores |
WO2015138405A2 (en) * | 2014-03-10 | 2015-09-17 | The Board Of Trustees Of The University Of Illinois | Detection and quantification of methylation in dna |
AU2015236392A1 (en) | 2014-03-24 | 2016-10-20 | Genia Technologies, Inc. | Chemical methods for producing tagged nucleotides |
WO2015150786A1 (en) | 2014-04-04 | 2015-10-08 | Oxford Nanopore Technologies Limited | Method for characterising a double stranded nucleic acid using a nano-pore and anchor molecules at both ends of said nucleic acid |
US10781237B2 (en) | 2014-04-16 | 2020-09-22 | The Uab Research Foundation | MSP nanopores and uses thereof |
EP3137627A1 (en) * | 2014-05-02 | 2017-03-08 | Oxford Nanopore Technologies Limited | Method of improving the movement of a target polynucleotide with respect to a transmembrane pore |
ES2846746T3 (es) | 2014-06-03 | 2021-07-29 | Illumina Inc | Composiciones, sistemas y métodos para detectar acontecimientos usando fijaciones ancladas o adyacentes a nanoporos |
SG10201809900PA (en) | 2014-07-31 | 2018-12-28 | Illumina Inc | Hybrid Nanopore Sensors |
CA2959220A1 (en) | 2014-09-01 | 2016-03-10 | Vib Vzw | Mutant csgg pores |
US10266885B2 (en) | 2014-10-07 | 2019-04-23 | Oxford Nanopore Technologies Ltd. | Mutant pores |
EP3207154B1 (en) * | 2014-10-16 | 2022-03-16 | Oxford Nanopore Technologies PLC | Analysis of a polymer |
GB201418469D0 (en) | 2014-10-17 | 2014-12-03 | Oxford Nanopore Tech Ltd | Method |
US9624537B2 (en) | 2014-10-24 | 2017-04-18 | Quantapore, Inc. | Efficient optical analysis of polymers using arrays of nanostructures |
GB201502810D0 (en) | 2015-02-19 | 2015-04-08 | Oxford Nanopore Tech Ltd | Method |
GB201502809D0 (en) | 2015-02-19 | 2015-04-08 | Oxford Nanopore Tech Ltd | Mutant pore |
EP3283887B1 (en) | 2015-04-14 | 2021-07-21 | Katholieke Universiteit Leuven | Nanopores with internal protein adaptors |
CN114703264B (zh) | 2015-06-03 | 2024-09-20 | 亿明达股份有限公司 | 使用锚定至邻近纳米孔的聚合酶的系链对多核苷酸测序的组合物、系统和方法 |
WO2017098322A1 (en) | 2015-12-08 | 2017-06-15 | Katholieke Universiteit Leuven Ku Leuven Research & Development | Modified nanopores, compositions comprising the same, and uses thereof |
CN105779279A (zh) * | 2016-02-29 | 2016-07-20 | 东南大学 | 一种基于二维层状材料的纳米孔传感器件及其构建方法 |
WO2017149317A1 (en) | 2016-03-02 | 2017-09-08 | Oxford Nanopore Technologies Limited | Mutant pore |
EP4397970A3 (en) | 2016-04-06 | 2024-10-09 | Oxford Nanopore Technologies PLC | Mutant pore |
US11124827B2 (en) * | 2016-06-23 | 2021-09-21 | Roche Sequencing Solutions, Inc. | Period-to-period analysis of AC signals from nanopore sequencing |
GB201707122D0 (en) | 2017-05-04 | 2017-06-21 | Oxford Nanopore Tech Ltd | Pore |
WO2018209286A1 (en) * | 2017-05-12 | 2018-11-15 | Ust Corporation | Method and systems for pulling dna, rna and other biological molecules through nanopores using soft magnetic structures |
CN110914290A (zh) | 2017-06-30 | 2020-03-24 | 弗拉芒区生物技术研究所 | 新颖蛋白孔 |
CN111512155B (zh) | 2017-12-28 | 2022-07-05 | 豪夫迈·罗氏有限公司 | 测量和去除来自交流信号驱动的纳米孔dna测序系统的随机信号中的噪声 |
WO2019133756A1 (en) | 2017-12-29 | 2019-07-04 | Clear Labs, Inc. | Automated priming and library loading device |
US11391693B2 (en) | 2018-02-16 | 2022-07-19 | Illumina, Inc. | Device for sequencing |
US12195794B2 (en) * | 2018-05-23 | 2025-01-14 | The Regents Of The University Of California | Methods of analyzing capped ribonucleic acids |
GB201811623D0 (en) | 2018-07-16 | 2018-08-29 | Univ Oxford Innovation Ltd | Molecular hopper |
WO2020043082A1 (en) * | 2018-08-28 | 2020-03-05 | Nanjing University | Protein nanopore for identifying an analyte |
US20220366313A1 (en) * | 2019-02-14 | 2022-11-17 | University Of Washington | Systems and methods for improved nanopore-based analysis of nucleic acids |
CN112831395B (zh) * | 2019-11-25 | 2024-01-16 | 深圳华大生命科学研究院 | 用于纳米孔测序的类细胞膜 |
CN111424075B (zh) * | 2020-04-10 | 2021-01-15 | 西咸新区予果微码生物科技有限公司 | 一种基于第三代测序技术的微生物检测方法及系统 |
ES2999861T3 (en) | 2020-08-11 | 2025-02-27 | Hoffmann La Roche | Nucleoside-5'-oligophosphates tagged with positively-charged polymers, nanopores incorporating negative charges, and methods and systems using the same |
US20240272137A1 (en) * | 2021-05-13 | 2024-08-15 | Nanjing University | Structural-profiling of analytes by nanopore trapping |
WO2022263496A1 (en) | 2021-06-17 | 2022-12-22 | F. Hoffmann-La Roche Ag | Engineered nanopore with a negatively charged polymer threaded through the channel |
CN114199875B (zh) * | 2022-02-18 | 2022-05-20 | 之江实验室 | 一种蛋白质多聚体是否可作为力缓冲剂的判断方法及装置 |
Family Cites Families (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4307229A (en) | 1979-11-07 | 1981-12-22 | Avraham Liav | 6,6'-Diesters of trehalose and process for the synthesis thereof |
US4554101A (en) | 1981-01-09 | 1985-11-19 | New York Blood Center, Inc. | Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity |
DE3248167A1 (de) | 1982-12-27 | 1984-06-28 | Wintershall Ag, 3100 Celle | Trehaloselipidtetraester |
WO1987005606A1 (en) | 1986-03-20 | 1987-09-24 | Sawai Pharmaceutical Co., Ltd. | alpha, alpha-TREHALOSE TRIMYCOLATE AND MEDICINAL COMPOSITION |
US5049664A (en) | 1988-08-26 | 1991-09-17 | Sawai Pharmaceutical Co., Ltd. | Trehalose derivatives |
JPH07248329A (ja) * | 1994-03-11 | 1995-09-26 | Nippon Bio Ratsudo Lab Kk | 結核感染症検査用膜およびこれを用いる結核感染症関連抗体の検出方法 |
US5658749A (en) * | 1994-04-05 | 1997-08-19 | Corning Clinical Laboratories, Inc. | Method for processing mycobacteria |
US6171830B1 (en) * | 1995-02-22 | 2001-01-09 | Adcock Ingram Limited | Method for the isolation and purification of lipid cell-wall components |
US5795782A (en) | 1995-03-17 | 1998-08-18 | President & Fellows Of Harvard College | Characterization of individual polymer molecules based on monomer-interface interactions |
US6362002B1 (en) * | 1995-03-17 | 2002-03-26 | President And Fellows Of Harvard College | Characterization of individual polymer molecules based on monomer-interface interactions |
DE69839782D1 (de) * | 1997-03-03 | 2008-09-04 | Adcock Ingram Ltd | Eine Zusammensetzung, die eine Trägerkomponente und eine gereinigte mykobakterielle Zellwandkomponente enthält, und ihre Verwendung zur Verhinderung, Behandlung und Diagnose von Erkrankungen |
US6406880B1 (en) * | 1997-05-02 | 2002-06-18 | Integrated Research Technology, Llc | Betaines as adjuvants to susceptibility testing and antimicrobial therapy |
US6267872B1 (en) | 1998-11-06 | 2001-07-31 | The Regents Of The University Of California | Miniature support for thin films containing single channels or nanopores and methods for using same |
NO986133D0 (no) | 1998-12-23 | 1998-12-23 | Preben Lexow | FremgangsmÕte for DNA-sekvensering |
WO2000039333A1 (en) | 1998-12-23 | 2000-07-06 | Jones Elizabeth Louise | Sequencing method using magnifying tags |
AU783675B2 (en) | 1999-09-07 | 2005-11-24 | Regents Of The University Of California, The | Methods of determining the presence of double stranded nucleic acids in a sample |
US7713544B2 (en) * | 2000-07-28 | 2010-05-11 | Emory University | Biological component comprising artificial membrane |
US6936433B2 (en) | 2000-11-27 | 2005-08-30 | The Regents Of The University Of California | Methods and devices for characterizing duplex nucleic acid molecules |
US6833249B2 (en) * | 2002-03-22 | 2004-12-21 | Council Of Scientific And Industrial Research | Quick and sensitive method of quantifying mycolic acid to develop anti-microbial agents and a diagnostic kit thereof |
ITMI20022096A1 (it) | 2002-10-03 | 2004-04-04 | Garden Ventures S R L | Sistema di registrazione di un programma tv impostabile |
CA2515213A1 (en) | 2003-02-11 | 2004-08-26 | University Of Washington | Stimuli-responsive polymer conjugates and related methods |
US7444053B2 (en) | 2003-06-16 | 2008-10-28 | The Regents Of The University Of California | Integrated electrical and optical sensor for biomolecule analysis with single molecule sensitivity |
US7594359B2 (en) | 2004-03-12 | 2009-09-29 | Gm Global Technology Operations, Inc. | Active seal assemblies for sound isolation |
US7238485B2 (en) | 2004-03-23 | 2007-07-03 | President And Fellows Of Harvard College | Methods and apparatus for characterizing polynucleotides |
US20070269843A1 (en) * | 2004-04-28 | 2007-11-22 | Integrated Research Technology, Llc. | Diagnostic Assays That Use Mycobacteriophages |
US7749520B2 (en) * | 2004-07-07 | 2010-07-06 | Statens Serum Institut | Compositions and methods for stabilizing lipid based adjuvant formulations using glycolipids |
US7972858B2 (en) * | 2004-08-13 | 2011-07-05 | President And Fellows Of Harvard College | Ultra high-throughput opti-nanopore DNA readout platform |
GB0504184D0 (en) | 2005-03-01 | 2005-04-06 | Lingvitae As | Method |
US7514267B1 (en) | 2005-08-19 | 2009-04-07 | Stcunm | Detection systems utilizing supported lipid bilayers |
US20070190542A1 (en) | 2005-10-03 | 2007-08-16 | Ling Xinsheng S | Hybridization assisted nanopore sequencing |
US8889348B2 (en) * | 2006-06-07 | 2014-11-18 | The Trustees Of Columbia University In The City Of New York | DNA sequencing by nanopore using modified nucleotides |
GB2457851B (en) * | 2006-12-14 | 2011-01-05 | Ion Torrent Systems Inc | Methods and apparatus for measuring analytes using large scale fet arrays |
EP2126588A1 (en) | 2007-02-20 | 2009-12-02 | Oxford Nanopore Technologies Limited | Formation of lipid bilayers |
JP5646987B2 (ja) * | 2007-04-04 | 2014-12-24 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | ナノポアを使用するための組成物、デバイス、システム、及び方法 |
ES2584871T3 (es) | 2007-05-08 | 2016-09-29 | Prionics Ag | Método para el diagnóstico de la tuberculosis |
GB0807305D0 (en) * | 2008-04-22 | 2008-05-28 | Univ Ghent | Compounds for use in therapy |
EP2344891B1 (en) | 2008-09-22 | 2016-03-16 | University Of Washington | Msp nanopores and related methods |
DK2539465T3 (da) | 2010-02-23 | 2024-03-11 | Univ Washington | Analytsekventering med nanoporer |
US9893808B2 (en) | 2016-03-18 | 2018-02-13 | Target Brands, Inc. | VLC location data applications in a retail setting |
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