DK2440230T3 - Behandlingsregimener til behandling af neurologisk sygdom - Google Patents
Behandlingsregimener til behandling af neurologisk sygdom Download PDFInfo
- Publication number
- DK2440230T3 DK2440230T3 DK10786859.8T DK10786859T DK2440230T3 DK 2440230 T3 DK2440230 T3 DK 2440230T3 DK 10786859 T DK10786859 T DK 10786859T DK 2440230 T3 DK2440230 T3 DK 2440230T3
- Authority
- DK
- Denmark
- Prior art keywords
- treatment
- neurological disease
- regimes
- treatment regimes
- neurological
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/162—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/10—Fusion polypeptide containing a localisation/targetting motif containing a tag for extracellular membrane crossing, e.g. TAT or VP22
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Toxicology (AREA)
- Urology & Nephrology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Management, Administration, Business Operations System, And Electronic Commerce (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18598909P | 2009-06-10 | 2009-06-10 | |
| PCT/US2010/038200 WO2010144721A2 (en) | 2009-06-10 | 2010-06-10 | Model systems and treatment regimes for treatment of neurological disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2440230T3 true DK2440230T3 (da) | 2021-01-18 |
Family
ID=43309469
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK10786859.8T DK2440230T3 (da) | 2009-06-10 | 2010-06-10 | Behandlingsregimener til behandling af neurologisk sygdom |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US8940699B2 (da) |
| EP (2) | EP2440230B1 (da) |
| JP (2) | JP6005514B2 (da) |
| CN (1) | CN102458441A (da) |
| AU (1) | AU2010258664B2 (da) |
| BR (1) | BRPI1010718A2 (da) |
| CA (1) | CA2765169C (da) |
| DK (1) | DK2440230T3 (da) |
| ES (1) | ES2847293T3 (da) |
| HR (1) | HRP20210112T1 (da) |
| HU (1) | HUE053131T2 (da) |
| PL (1) | PL2440230T3 (da) |
| PT (1) | PT2440230T (da) |
| WO (1) | WO2010144721A2 (da) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7510824B2 (en) * | 1999-06-02 | 2009-03-31 | Nono Inc. | Method of screening peptides useful in treating traumatic injury to the brain or spinal cord |
| ES2847293T3 (es) | 2009-06-10 | 2021-08-02 | Nono Inc | Regímenes de tratamiento para el tratamiento de enfermedades neurológicas |
| WO2012021854A2 (en) | 2010-08-12 | 2012-02-16 | Nono, Inc. | Treatment of penetrative injury to the brain |
| PT2723363T (pt) | 2011-06-24 | 2018-11-08 | Nono Inc | Terapia de combinação para isquemia |
| US9241970B2 (en) | 2011-12-13 | 2016-01-26 | Nono Inc. | Therapy for subarachnoid hemorrhage and ischemia |
| WO2013088382A1 (en) * | 2011-12-13 | 2013-06-20 | Nono Inc. | Therapy for subarachnoid hemorrhage and ischemia |
| AU2013204309A1 (en) * | 2012-11-13 | 2014-05-29 | Biodiem Limited | Therapeutic Compounds and Uses Thereof |
| SI2925338T1 (sl) * | 2012-11-28 | 2019-09-30 | Nono Inc. | Liofilizirana formulacija TAT-NR2B9C |
| US10251935B2 (en) | 2012-11-28 | 2019-04-09 | Nono Inc. | Lyophilized formulation comprising tat-NR2B9C, histidine and trehalose |
| WO2015181756A1 (en) * | 2014-05-28 | 2015-12-03 | Nono Inc. | Chloride salt of tat-nr2b9c |
| EP3450446A1 (en) * | 2016-04-27 | 2019-03-06 | Biocells (Beijing) Biotech Co., Ltd. | Treatment method for excitatory neurotoxicity-related injury |
| EP3450448B1 (en) * | 2016-04-27 | 2021-04-07 | Biocells (Beijing) Biotech Co., Ltd. | Therapeutic peptide for excitatory neurotoxicity-related injuries |
| CN110049994B (zh) * | 2016-12-08 | 2023-05-02 | 拜西欧斯（北京）生物技术有限公司 | 一种缀合物及其应用 |
| JP7002788B2 (ja) * | 2017-07-05 | 2022-03-03 | 拜西欧斯（北京）生物技術有限公司 | ポリペプチドの薬学的に許容される塩およびその使用 |
| CN110799547B (zh) * | 2017-07-05 | 2023-02-28 | 拜西欧斯（北京）生物技术有限公司 | 用于治疗、改善或预防神经系统相关病症的化合物及其用途 |
| JP7073486B2 (ja) * | 2017-09-30 | 2022-05-23 | ▲拝▼西欧斯（北京）生物技▲術▼有限公司 | 興奮性神経毒性に関連した損傷の治療用ペプチド組成物 |
| CN113150065B (zh) | 2021-03-11 | 2022-07-08 | 武汉英纳氏药业有限公司 | 一种合成肽及其应用 |
| CN113121641B (zh) | 2021-03-11 | 2022-11-01 | 武汉英纳氏药业有限公司 | 一类多功能多肽及其在医药领域的应用 |
| CN113735938B (zh) * | 2021-07-30 | 2024-11-08 | 英纳氏(珠海)药业有限公司 | 一种神经保护多肽化合物及其应用 |
| CN114642402A (zh) * | 2022-03-07 | 2022-06-21 | 翰博瑞强(上海)医药科技有限公司 | 一种用于预测药物对心脏毒性影响的方法及心电图设备 |
| CN114469084B (zh) * | 2022-04-02 | 2022-06-24 | 剑博微电子(深圳)有限公司 | 一种基于高精度adc的血氧监测系统 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060148711A1 (en) | 1999-05-14 | 2006-07-06 | Arbor Vita Corporation | Molecular interactions in neurons |
| US7510824B2 (en) | 1999-06-02 | 2009-03-31 | Nono Inc. | Method of screening peptides useful in treating traumatic injury to the brain or spinal cord |
| GB0025473D0 (en) | 2000-10-17 | 2000-11-29 | Pfizer Ltd | Pharmaceutical combinations |
| EP1578365A4 (en) * | 2002-11-14 | 2009-09-23 | Arbor Vita Corp | MOLECULAR INTERACTIONS IN NEURONS |
| US20060276455A1 (en) | 2003-02-13 | 2006-12-07 | Lindsberg Perttu J | Use of a mast cell activation or degranulation blocking agent in the manufacture of a medicament for the treatment of cerebral ischemia |
| CA2524573A1 (en) | 2003-05-02 | 2004-11-11 | Paion Deutschland Gmbh | Intravenous injection of non-neurotoxic plasminogen activators for the treatment of stroke |
| JP5746468B2 (ja) | 2006-07-11 | 2015-07-08 | ノノ インコーポレイテッド | 発熱を伴う脳卒中を処置する方法および組成物 |
| EP1884521A1 (en) | 2006-07-31 | 2008-02-06 | Xigen S.A. | Fusion peptide for inhibiting interaction of neuronal NMDA receptor (NMDAR) and NMDAR interacting proteins |
| JP5631595B2 (ja) * | 2007-03-02 | 2014-11-26 | ノノ インコーポレイテッド | Ｎ型カルシウムチャネルを阻害せずに卒中および他の疾患を治療する方法 |
| WO2009006611A1 (en) | 2007-07-03 | 2009-01-08 | Arbor Vita Corporation | Small molecule inhibitors of pdz interactions |
| US8080518B2 (en) | 2007-12-05 | 2011-12-20 | Arbor Vita Corporation | Co-administration of an agent linked to an internalization peptide with an anti-inflammatory |
| US9241967B2 (en) | 2008-07-09 | 2016-01-26 | University Of Copenhagen | Modified peptides as potent inhibitors of the PSD-95/NMDA receptor interaction |
| ES2847293T3 (es) | 2009-06-10 | 2021-08-02 | Nono Inc | Regímenes de tratamiento para el tratamiento de enfermedades neurológicas |
| PT2723363T (pt) | 2011-06-24 | 2018-11-08 | Nono Inc | Terapia de combinação para isquemia |
| US9241970B2 (en) | 2011-12-13 | 2016-01-26 | Nono Inc. | Therapy for subarachnoid hemorrhage and ischemia |
| WO2013088382A1 (en) | 2011-12-13 | 2013-06-20 | Nono Inc. | Therapy for subarachnoid hemorrhage and ischemia |
-
2010
- 2010-06-10 ES ES10786859T patent/ES2847293T3/es active Active
- 2010-06-10 CA CA2765169A patent/CA2765169C/en active Active
- 2010-06-10 EP EP10786859.8A patent/EP2440230B1/en active Active
- 2010-06-10 HU HUE10786859A patent/HUE053131T2/hu unknown
- 2010-06-10 AU AU2010258664A patent/AU2010258664B2/en not_active Ceased
- 2010-06-10 EP EP20200385.1A patent/EP3808366A1/en not_active Withdrawn
- 2010-06-10 PL PL10786859T patent/PL2440230T3/pl unknown
- 2010-06-10 CN CN2010800352462A patent/CN102458441A/zh active Pending
- 2010-06-10 BR BRPI1010718A patent/BRPI1010718A2/pt not_active Application Discontinuation
- 2010-06-10 US US13/377,523 patent/US8940699B2/en active Active
- 2010-06-10 DK DK10786859.8T patent/DK2440230T3/da active
- 2010-06-10 JP JP2012515147A patent/JP6005514B2/ja not_active Expired - Fee Related
- 2010-06-10 WO PCT/US2010/038200 patent/WO2010144721A2/en active Application Filing
- 2010-06-10 PT PT107868598T patent/PT2440230T/pt unknown
-
2015
- 2015-01-14 US US14/597,166 patent/US9610323B2/en active Active
- 2015-10-30 JP JP2015214926A patent/JP6220371B2/ja active Active
-
2021
- 2021-01-21 HR HRP20210112TT patent/HRP20210112T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2847293T3 (es) | 2021-08-02 |
| US20150202253A1 (en) | 2015-07-23 |
| JP6220371B2 (ja) | 2017-10-25 |
| EP2440230A4 (en) | 2014-05-28 |
| HUE053131T2 (hu) | 2021-06-28 |
| EP2440230A2 (en) | 2012-04-18 |
| US9610323B2 (en) | 2017-04-04 |
| CA2765169C (en) | 2019-06-18 |
| PT2440230T (pt) | 2021-02-03 |
| US20120269733A1 (en) | 2012-10-25 |
| AU2010258664A1 (en) | 2012-01-12 |
| CA2765169A1 (en) | 2010-12-16 |
| US8940699B2 (en) | 2015-01-27 |
| AU2010258664B2 (en) | 2015-05-28 |
| CN102458441A (zh) | 2012-05-16 |
| HRP20210112T1 (hr) | 2021-04-16 |
| EP2440230B1 (en) | 2020-11-11 |
| PL2440230T3 (pl) | 2021-06-14 |
| EP3808366A1 (en) | 2021-04-21 |
| JP2016041731A (ja) | 2016-03-31 |
| WO2010144721A3 (en) | 2011-04-21 |
| JP2012530057A (ja) | 2012-11-29 |
| WO2010144721A2 (en) | 2010-12-16 |
| BRPI1010718A2 (pt) | 2016-03-15 |
| JP6005514B2 (ja) | 2016-10-12 |
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