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DK229876A - Fremgangsmade til fremstilling af estere af alfa-methyl-3,4-dihydroxyphenylalanin - Google Patents

Fremgangsmade til fremstilling af estere af alfa-methyl-3,4-dihydroxyphenylalanin

Info

Publication number
DK229876A
DK229876A DK229876A DK229876A DK229876A DK 229876 A DK229876 A DK 229876A DK 229876 A DK229876 A DK 229876A DK 229876 A DK229876 A DK 229876A DK 229876 A DK229876 A DK 229876A
Authority
DK
Denmark
Prior art keywords
dihydroxyphenylalanine
alfa
methyl
procedure
making esters
Prior art date
Application number
DK229876A
Other languages
English (en)
Inventor
B F Powell
R F Hirschmann
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK229876A publication Critical patent/DK229876A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36Oxygen or sulfur atoms
    • C07D207/402,5-Pyrrolidine-diones
    • C07D207/4042,5-Pyrrolidine-diones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. succinimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/60Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK229876A 1975-06-11 1976-05-25 Fremgangsmade til fremstilling af estere af alfa-methyl-3,4-dihydroxyphenylalanin DK229876A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US58600775A 1975-06-11 1975-06-11

Publications (1)

Publication Number Publication Date
DK229876A true DK229876A (da) 1976-12-12

Family

ID=24343905

Family Applications (1)

Application Number Title Priority Date Filing Date
DK229876A DK229876A (da) 1975-06-11 1976-05-25 Fremgangsmade til fremstilling af estere af alfa-methyl-3,4-dihydroxyphenylalanin

Country Status (7)

Country Link
JP (1) JPS51149241A (da)
DE (1) DE2626095A1 (da)
DK (1) DK229876A (da)
FR (1) FR2313922A1 (da)
GB (1) GB1518745A (da)
NL (1) NL7605698A (da)
SE (1) SE7605911L (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57112385A (en) * 1980-12-29 1982-07-13 Suntory Ltd Production of mugineic acids
US4440942A (en) * 1982-03-01 1984-04-03 Merck & Co., Inc. Crystalline diastereomeric L-alpha-methyldopa POE ester and process for its preparation
LU85757A1 (fr) * 1985-02-04 1986-09-02 Univ Catholique Louvain Derives nouveaux de la l-dopa,procedes pour leur preparation et compositions pharmaceutiques concernant de tels composes

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3983138A (en) * 1973-09-25 1976-09-28 Merck & Co., Inc. Amino acid esters

Also Published As

Publication number Publication date
DE2626095A1 (de) 1976-12-30
JPS51149241A (en) 1976-12-22
NL7605698A (nl) 1976-12-14
GB1518745A (en) 1978-07-26
FR2313922B1 (da) 1979-09-21
FR2313922A1 (fr) 1977-01-07
SE7605911L (sv) 1976-12-12

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