DK226288A - Fremgangsmaade til fremstilling af lak-celler in vitro - Google Patents

Fremgangsmaade til fremstilling af lak-celler in vitro

Info

Publication number: DK226288A
Authority: DK; Denmark
Prior art keywords: vitro; manufacturing; lak cells; centrifugation; standard
Prior art date: 1987-04-27

Application number

DK226288A

Other languages

Danish (da)

English (en)

Other versions

DK226288D0 (da

Inventor

Jr George Franks Dunn

Joseph David Irr

Lise Nadine Halpern

Original Assignee

Du Pont

Haemonetics Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-04-27

Filing date

1988-04-26

Publication date

1988-10-28

1988-04-26 Application filed by Du Pont, Haemonetics Corp filed Critical Du Pont

1988-04-26 Publication of DK226288D0 publication Critical patent/DK226288D0/da

1988-10-28 Publication of DK226288A publication Critical patent/DK226288A/da

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0081—Purging biological preparations of unwanted cells
- C12N5/0087—Purging against subsets of blood cells, e.g. purging alloreactive T cells
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/32—Amino acids
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
General Engineering & Computer Science (AREA)
Microbiology (AREA)
Cell Biology (AREA)
Biochemistry (AREA)
Immunology (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Hematology (AREA)
Molecular Biology (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Peptides Or Proteins (AREA)

DK226288A 1987-04-27 1988-04-26 Fremgangsmaade til fremstilling af lak-celler in vitro DK226288A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/042,998 US4808151A (en)	1987-04-27	1987-04-27	Simplified method for the preparation of human lymphokine activated killer cells

Publications (2)

Publication Number	Publication Date
DK226288D0 DK226288D0 (da)	1988-04-26
DK226288A true DK226288A (da)	1988-10-28

Family

ID=21924902

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK226288A DK226288A (da)	1987-04-27	1988-04-26	Fremgangsmaade til fremstilling af lak-celler in vitro

Country Status (17)

Country	Link
US (1)	US4808151A (de)
EP (1)	EP0289896B1 (de)
JP (1)	JPH0657147B2 (de)
KR (1)	KR900004422B1 (de)
AT (1)	ATE78053T1 (de)
AU (1)	AU612086B2 (de)
CA (1)	CA1304306C (de)
DE (1)	DE3872588T2 (de)
DK (1)	DK226288A (de)
ES (1)	ES2051790T3 (de)
FI (1)	FI881952L (de)
HU (1)	HU205380B (de)
IL (1)	IL86177A0 (de)
NO (1)	NO881819L (de)
NZ (1)	NZ224379A (de)
PT (1)	PT87335B (de)
ZA (1)	ZA882948B (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU7873187A (en) *	1986-08-08	1988-02-24	University Of Minnesota	Method of culturing leukocytes
AU4485089A (en) *	1988-10-21	1990-05-14	Brigham And Women's Hospital	Activation and growth of human tumor-infiltrating lymphocytes using antibodies to cd3 or tcr
JP2955314B2 (ja) *	1988-10-27	1999-10-04	リージェンツ・オブ・ザ・ユニバーシティー・オブ・ミネソタ	Ｉｌ―２含有リポソーム免疫アジュバント
US5484396A (en) *	1988-11-17	1996-01-16	Naficy; Sadeque S.	Method and device for treatment of HIV infections and AIDS
DK0460065T3 (da) *	1989-02-21	1994-09-26	Terumo Corp	Fremgangsmåde til at fremkalde formering af CD4-lymfocytter
US5912170A (en) *	1991-03-07	1999-06-15	The General Hospital Corporation	Redirection of cellular immunity by protein-tyrosine kinase chimeras
US7049136B2 (en)	1991-03-07	2006-05-23	The General Hospital Corporation	Redirection of cellular immunity by receptor chimeras
US6004811A (en)	1991-03-07	1999-12-21	The Massachussetts General Hospital	Redirection of cellular immunity by protein tyrosine kinase chimeras
US5843728A (en) *	1991-03-07	1998-12-01	The General Hospital Corporation	Redirection of cellular immunity by receptor chimeras
US5851828A (en) *	1991-03-07	1998-12-22	The General Hospital Corporation	Targeted cytolysis of HIV-infected cells by chimeric CD4 receptor-bearing cells
US6753162B1 (en)	1991-03-07	2004-06-22	The General Hospital Corporation	Targeted cytolysis of HIV-infected cells by chimeric CD4 receptor-bearing cells
US5725855A (en) *	1991-04-05	1998-03-10	The United States Of America As Represented By The Department Of Health And Human Services	Method of treating tumors with CD8+ -depleted or CD4+ T cell subpopulations
JPH06506465A (ja) *	1991-04-05	1994-07-21	リージエンツ・オブ・ザ・ユニバーシテイ・オブ・ミネソタ	細胞サブセットの欠落／陽性選択による免疫細胞の免疫療法活性の増強方法
IE922233A1 (en) *	1991-07-10	1993-01-13	Augusto C Ochoa	Short-term anti-cd3 stimulation of lymphocytes to increase¹their in vivo activity
JPH07502734A (ja) *	1991-12-31	1995-03-23	ザイモジェネティクス，インコーポレイティド	血液損失を減少する方法および組成物
US5913768A (en) *	1995-04-18	1999-06-22	Cobe Laboratories, Inc.	Particle filter apparatus
DE69637310T2 (de) *	1995-04-18	2008-08-28	Gambro BCT, Inc., Lakewood	Vorrichtung und Verfahren zur Teilchentrennung
US5674173A (en) *	1995-04-18	1997-10-07	Cobe Laboratories, Inc.	Apparatus for separating particles
US6053856A (en) *	1995-04-18	2000-04-25	Cobe Laboratories	Tubing set apparatus and method for separation of fluid components
US6022306A (en) *	1995-04-18	2000-02-08	Cobe Laboratories, Inc.	Method and apparatus for collecting hyperconcentrated platelets
US20020182730A1 (en) *	1995-07-26	2002-12-05	Micheal L. Gruenberg	Autologous immune cell therapy: cell compositions, methods and applications to treatment of human disease
US6051146A (en) *	1998-01-20	2000-04-18	Cobe Laboratories, Inc.	Methods for separation of particles
US6153113A (en) *	1999-02-22	2000-11-28	Cobe Laboratories, Inc.	Method for using ligands in particle separation
US6334842B1 (en)	1999-03-16	2002-01-01	Gambro, Inc.	Centrifugal separation apparatus and method for separating fluid components
US6354986B1 (en)	2000-02-16	2002-03-12	Gambro, Inc.	Reverse-flow chamber purging during centrifugal separation
FR2821947B1 (fr) *	2001-03-12	2003-05-16	Canon Kk	Procede et dispositif de validation de parametres definissant une image
US20030134341A1 (en) *	2001-09-19	2003-07-17	Medcell Biologics, Llc.	Th1 cell adoptive immunotherapy
US20030134415A1 (en) *	2001-09-19	2003-07-17	Gruenberg Micheal L.	Th1 cell adoptive immunotherapy
US7201848B2 (en) *	2001-12-05	2007-04-10	Gambro Bct, Inc.	Methods and apparatus for separation of particles
US20030173274A1 (en) *	2002-02-01	2003-09-18	Frank Corbin	Blood component separation device, system, and method including filtration
US20030175272A1 (en) *	2002-03-07	2003-09-18	Medcell Biologics, Inc.	Re-activated T-cells for adoptive immunotherapy
DE60318418T2 (de) *	2002-04-16	2009-01-02	Gambro BCT, Inc., Lakewood	System und verfahren zur aufarbeitung von blutbestandteilen
CN1291231C (zh)	2003-12-08	2006-12-20	胡军	活化淋巴细胞特异性的检测方法
US20080035585A1 (en) *	2006-08-10	2008-02-14	Gambro Bct, Inc.	Method and Apparatus for Recirculating Elutriation Fluids
DE102011106914B4 (de)	2011-07-08	2015-08-27	Zellwerk Gmbh	Mäander- Bioreaktor und Verfahren zu dynamischen Expansion, Differenzierung und Ernte von hämatopoetischen Zellen
WO2014127122A1 (en)	2013-02-18	2014-08-21	Terumo Bct, Inc.	System for blood separation with a separation chamber having an internal gravity valve
WO2017209498A1 (ko) *	2016-06-03	2017-12-07	주식회사 젬백스앤카엘	항암 치료용 사이토카인 유도 살해세포의 생산 방법

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3145713A (en) *	1963-09-12	1964-08-25	Protein Foundation Inc	Method and apparatus for processing blood
US4197847A (en) *	1977-03-31	1980-04-15	Isaac Djerassi	Method and apparatus for collecting transfusable granulocytes
US4185629A (en) *	1977-10-18	1980-01-29	Baxter Travenol Laboratories, Inc.	Method and apparatus for processing blood
US4151844A (en) *	1977-11-11	1979-05-01	Baxter Travenol Laboratories, Inc.	Method and apparatus for separating whole blood into its components and for automatically collecting one component
US4285464A (en) *	1979-01-22	1981-08-25	Haemonetics Corporation	Apparatus for separation of blood into components thereof
US4401756A (en) *	1981-04-14	1983-08-30	Immunex Corporation	Process for preparing human interleukin 2
US4464166A (en) *	1981-06-12	1984-08-07	Frederic A. Bourke, Jr.	Method for externally treating the blood
US4464167A (en) *	1981-09-03	1984-08-07	Haemonetics Corporation	Pheresis apparatus
US4416654A (en) *	1981-09-03	1983-11-22	Haemonetics Corporation	Pheresis apparatus
JPS5998015A (ja) *	1982-11-27	1984-06-06	Microbial Chem Res Found	免疫賦活剤
US4613322A (en) *	1982-12-08	1986-09-23	Edelson Richard Leslie	Method and system for externally treating the blood
US4683889A (en) *	1983-03-29	1987-08-04	Frederic A. Bourke, Jr.	Method and system for externally treating the blood
US4675383A (en) *	1983-11-15	1987-06-23	The Salk Institute For Biological Studies	Purification of T-cell growth factor
US4578056A (en) *	1984-10-29	1986-03-25	Extracorporeal Medical Specialties, Inc.	Patient photopheresis treatment apparatus and method
US4690915A (en) *	1985-08-08	1987-09-01	The United States Of America As Represented By The Department Of Health And Human Services	Adoptive immunotherapy as a treatment modality in humans

1987
- 1987-04-27 US US07/042,998 patent/US4808151A/en not_active Expired - Fee Related
1988
- 1988-03-22 CA CA000562097A patent/CA1304306C/en not_active Expired - Lifetime
- 1988-04-23 DE DE8888106566T patent/DE3872588T2/de not_active Expired - Lifetime
- 1988-04-23 EP EP88106566A patent/EP0289896B1/de not_active Expired - Lifetime
- 1988-04-23 AT AT88106566T patent/ATE78053T1/de not_active IP Right Cessation
- 1988-04-23 ES ES88106566T patent/ES2051790T3/es not_active Expired - Lifetime
- 1988-04-26 JP JP63101509A patent/JPH0657147B2/ja not_active Expired - Lifetime
- 1988-04-26 ZA ZA882948A patent/ZA882948B/xx unknown
- 1988-04-26 FI FI881952A patent/FI881952L/fi not_active Application Discontinuation
- 1988-04-26 NO NO881819A patent/NO881819L/no unknown
- 1988-04-26 IL IL86177A patent/IL86177A0/xx unknown
- 1988-04-26 PT PT87335A patent/PT87335B/pt not_active IP Right Cessation
- 1988-04-26 NZ NZ224379A patent/NZ224379A/en unknown
- 1988-04-26 DK DK226288A patent/DK226288A/da not_active Application Discontinuation
- 1988-04-27 AU AU15200/88A patent/AU612086B2/en not_active Expired
- 1988-04-27 KR KR1019880004761A patent/KR900004422B1/ko not_active IP Right Cessation
- 1988-04-27 HU HU882123A patent/HU205380B/hu not_active IP Right Cessation

Also Published As

Publication number	Publication date
FI881952A0 (fi)	1988-04-26
EP0289896B1 (de)	1992-07-08
US4808151A (en)	1989-02-28
ATE78053T1 (de)	1992-07-15
EP0289896A1 (de)	1988-11-09
PT87335B (pt)	1992-08-31
DE3872588D1 (de)	1992-08-13
FI881952L (fi)	1988-10-28
JPH0657147B2 (ja)	1994-08-03
KR900004422B1 (ko)	1990-06-25
NZ224379A (en)	1990-12-21
JPS63295510A (ja)	1988-12-01
ES2051790T3 (es)	1994-07-01
NO881819D0 (no)	1988-04-26
DE3872588T2 (de)	1992-12-03
PT87335A (pt)	1988-05-01
NO881819L (no)	1988-10-28
KR880012751A (ko)	1988-11-29
IL86177A0 (en)	1988-11-15
ZA882948B (en)	1989-12-27
HU205380B (en)	1992-04-28
AU1520088A (en)	1988-10-27
AU612086B2 (en)	1991-06-27
CA1304306C (en)	1992-06-30
DK226288D0 (da)	1988-04-26

Publication	Publication Date	Title
DK226288A (da)	1988-10-28	Fremgangsmaade til fremstilling af lak-celler in vitro
AU606894B2 (en)	1991-02-21	Viable cell labelling
AU641488B2 (en)	1993-09-23	Human hematopoietic stem cell
GB8513190D0 (en)	1985-06-26	Combustion of fuel & oxygen
ES2120946T3 (es)	1998-11-16	Sistemas y medios de cultivo celular.
EP0453453A4 (en)	1992-10-14	Leukaemia inhibitory factor from livestock species and use thereof to enhance implantation and development of embryonic cells
DE69332024D1 (de)	2002-07-18	Die trennung lebender säugetierzellen durch hoch geschwindigkeits-durchflusscytometrie
ATE59404T1 (de)	1991-01-15	Fermentationsanlage.
IL85112A0 (en)	1988-06-30	Method for blood cell separation
ES2001721A6 (es)	1988-06-01	Metodo y equipo de ensayo para detectar un componente de una reaccion quimiluminiscente.
EP0112154A3 (de)	1987-07-22	Verfahren zur Züchtung von lebenden Zellen
MY103370A (en)	1993-06-30	A simplified method for the preparation of human lymphokine activated killer cells
EP0257962A3 (de)	1989-05-24	Verfahren zur Behandlung von Umkreisblut für die Verbesserung der lymphokinaktivierten Töterzell-Immuntherapie
EP0201800A3 (en)	1989-03-08	A cholesterol-rich fraction, process therefor and use thereof in cell culture
FI871830A0 (fi)	1987-04-27	Immobilisering av celler som inte fastnar vid en baerare.
SU1082422A1 (ru)	1984-03-30	Способ определени активности интерферона в сыворотке и плазме крови
ATE97958T1 (de)	1993-12-15	Zellenzuchtverfahren fuer die produktion von aktiviertem protein-c.
FR2585722B1 (fr)	1987-11-20	Co-cultures d'hepatocytes et de cellules epitheliales de foie traitees
ES465060A1 (es)	1978-09-01	Un procedimiento de propagacion de celulas en un sistema de cultivo.
UA12063A1 (uk)	1996-12-25	Спосіб культивуваhhя острівцевих клітиh підшлуhкової залози
GB8729410D0 (en)	1988-02-03	Method for production of lymphokine activated killer(lak)cells & lak cells so produced
KR870005089A (ko)	1987-06-04	유가배양에 의한 고농도 폴리-β-하이드록시부틸산(poly-β-hydroxybutyric-acid)의 제조방법
KR870008023A (ko)	1987-09-23	락트 알부민 하이드로리 세이트의 첨가에 의한 인터페론의 생산 증강법
GB8817082D0 (en)	1988-08-24	Method for production of lymphokine activated killer(lak)cells so produced & their use

Legal Events

Date	Code	Title	Description
2001-08-13	AHS	Application shelved for other reasons than non-payment