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DK1919450T3 - Antihistamin- og corticosteroidholdig liposomsammensætning og dens anvendelse til fremstilling af et lægemiddel til behandling af rhinitis og beslægtede lidelser - Google Patents

Antihistamin- og corticosteroidholdig liposomsammensætning og dens anvendelse til fremstilling af et lægemiddel til behandling af rhinitis og beslægtede lidelser

Info

Publication number
DK1919450T3
DK1919450T3 DK06779244.0T DK06779244T DK1919450T3 DK 1919450 T3 DK1919450 T3 DK 1919450T3 DK 06779244 T DK06779244 T DK 06779244T DK 1919450 T3 DK1919450 T3 DK 1919450T3
Authority
DK
Denmark
Prior art keywords
antihistamine
corticosteroid
rhinitis
drug
manufacture
Prior art date
Application number
DK06779244.0T
Other languages
English (en)
Inventor
Lena Pereswetoff-Morath
Anders Carlsson
Torbjørn Bjerke
Original Assignee
Meda Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Meda Ab filed Critical Meda Ab
Application granted granted Critical
Publication of DK1919450T3 publication Critical patent/DK1919450T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965Non-condensed pyrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Otolaryngology (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DK06779244.0T 2005-09-01 2006-08-31 Antihistamin- og corticosteroidholdig liposomsammensætning og dens anvendelse til fremstilling af et lægemiddel til behandling af rhinitis og beslægtede lidelser DK1919450T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71282205P 2005-09-01 2005-09-01
PCT/GB2006/003222 WO2007026151A1 (en) 2005-09-01 2006-08-31 Antihistamine- and corticosteroid- containing liposome composition and its use for the manufacture of a medicament for treating rhinitis and related disorders

Publications (1)

Publication Number Publication Date
DK1919450T3 true DK1919450T3 (da) 2014-09-15

Family

ID=35219424

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06779244.0T DK1919450T3 (da) 2005-09-01 2006-08-31 Antihistamin- og corticosteroidholdig liposomsammensætning og dens anvendelse til fremstilling af et lægemiddel til behandling af rhinitis og beslægtede lidelser

Country Status (13)

Country Link
US (2) US20090324699A1 (da)
EP (1) EP1919450B1 (da)
JP (1) JP5393151B2 (da)
CN (1) CN101257891A (da)
BR (1) BRPI0615032A2 (da)
CA (1) CA2616515C (da)
DK (1) DK1919450T3 (da)
ES (1) ES2498795T3 (da)
PL (1) PL1919450T3 (da)
PT (1) PT1919450E (da)
RU (1) RU2444351C2 (da)
SI (1) SI1919450T1 (da)
WO (1) WO2007026151A1 (da)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8207188B2 (en) * 2006-04-07 2012-06-26 Michalis Nicolaou Treatment of diseases modulated by a H4 receptor agonist
US7378082B1 (en) 2007-11-05 2008-05-27 Inspire Pharmaceuticals, Inc. Method for treating allergic rhinitis without adverse effects
GB0719518D0 (en) * 2007-10-05 2007-11-14 Therapeutics Ltd E Therapy
AU2008334605B2 (en) * 2007-12-13 2013-07-18 Glaxo Group Limited Polypeptides, antibody variable domains & antagonists
PT3943069T (pt) * 2009-03-17 2025-02-21 Nicox Ophthalmics Inc Formulações oftálmicas de cetirizina e métodos de utilização
US8569273B2 (en) * 2009-03-17 2013-10-29 Aciex Therapeutics, Inc. Ophthalmic formulations of cetirizine and methods of use
ES2662710T3 (es) 2010-05-24 2018-04-09 Swedish Oat Fiber Ab Dispersión acuosa que comprende galactolípidos y método de producción de la misma
MX341109B (es) * 2010-10-06 2016-08-09 Mitsubishi Tanabe Pharma Corp Composiciones de bepotastina.
AU2012204557B2 (en) * 2011-01-04 2015-05-14 Ista Pharmaceuticals, Inc. Bepotastine compositions
CA2834968C (en) * 2011-01-05 2018-01-09 Livon Laboratories Methods of making liposomes, liposome compositions made by the methods, and methods of using the same
WO2013017821A1 (en) 2011-08-02 2013-02-07 Cipla Limited Pharmaceutical composition comprising ebastine and fluticasone
CN102614177B (zh) * 2012-03-06 2014-08-06 北京伟峰益民科技有限公司 卢帕他定在制备治疗慢性阻塞性肺病药物组合物中的应用
CN103830729A (zh) * 2012-11-26 2014-06-04 天津金耀集团有限公司 氟替卡松及其酯与h1受体拮抗剂的吸入剂
US9790215B2 (en) 2013-03-13 2017-10-17 Flatley Discovery Lab, Llc Pyridazinone compounds and methods for the treatment of cystic fibrosis
KR102226833B1 (ko) * 2013-06-28 2021-03-12 한미약품 주식회사 레보세티리진 및 몬테루카스트를 포함하는 안정성이 개선된 복합 과립 제형
US10758550B2 (en) 2013-10-04 2020-09-01 Glenmark Specialty S.A. Treatment of allergic rhinitis using a combination of mometasone and olopatadine
UA120587C2 (uk) * 2013-10-04 2020-01-10 Гленмарк Спешіалті С.А. Спосіб лікування алергічного риніту з використанням комбінації мометазону та олопатадину
US10653661B2 (en) 2013-10-04 2020-05-19 Glenmark Specialty S.A. Treatment of allergic rhinitis using a combination of mometasone and olopatadine
US11679210B2 (en) 2014-10-03 2023-06-20 Glenmark Specialty S.A. Dispensing device and pharmaceutical composition for the treatment of rhinitis
CN104997734A (zh) * 2015-06-25 2015-10-28 广州艾格生物科技有限公司 一种富马酸卢帕他定颗粒剂及制备方法
SG10201912650QA (en) * 2015-12-17 2020-02-27 Univ Nanyang Tech Nanoliposomes comprising corticosteroid as medicaments and methods to prepare them
WO2018119413A1 (en) * 2016-12-22 2018-06-28 Lipidair, Llc Targeted delivery methods and compositions for antihistamines
CN109125265A (zh) * 2017-06-13 2019-01-04 佛山英特医药科技有限公司 布地奈德脂质复合物及其制备方法
US12303635B2 (en) 2018-04-16 2025-05-20 Glenmark Specialty S.A. Dispensing device and pharmaceutical composition for the treatment of rhinitis
CN112823009A (zh) * 2019-08-28 2021-05-18 上海谷森医药有限公司 糠酸氟替卡松脂质体制剂及其制备方法
WO2021110173A1 (en) * 2019-12-06 2021-06-10 Anovent Pharmaceuticals Co., Ltd Liposome formulation of fluticasone propionate
EP4164614A1 (en) 2020-06-15 2023-04-19 Alkem Laboratories Limited Combination of alcaftadine and a corticosteroid
AU2021372255A1 (en) * 2020-10-30 2023-06-15 The Board Of Trustees Of The Leland Stanford Junior University Drugs targeting inflammation for the treatment of osteoarthritis and other inflammatory diseases
US20220280422A1 (en) * 2021-03-04 2022-09-08 Innovation for Success, LLC Solubilized melatonin
MX2023011546A (es) 2021-04-01 2023-10-06 Alkem Laboratories Ltd Composiciones nasales que comprenden alcaftadina.
CN114392235B (zh) * 2022-01-28 2023-06-27 成都大学 盐酸西替利嗪眼用脂质体、原位凝胶及其制备方法

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1523965A (en) * 1976-03-19 1978-09-06 Ici Ltd Pharmaceutical compositions containing steroids
US5141674A (en) * 1984-03-08 1992-08-25 Phares Pharmaceutical Research N.V. Methods of preparing pro-liposome dispersions and aerosols
US4839175A (en) * 1986-07-28 1989-06-13 Liposome Technology, Inc. Liposomes with enhanced retention on mucosal tissue
US4962022A (en) * 1986-09-22 1990-10-09 Becton Dickinson And Company Storage and use of liposomes
US5049388A (en) * 1986-11-06 1991-09-17 Research Development Foundation Small particle aerosol liposome and liposome-drug combinations for medical use
US5422120A (en) * 1988-05-30 1995-06-06 Depotech Corporation Heterovesicular liposomes
DE3836892A1 (de) * 1988-10-29 1990-05-03 Nattermann A & Cie Parenteral applizierbare, stabile arzneimittelloesungen
US5498420A (en) * 1991-04-12 1996-03-12 Merz & Co. Gmbh & Co. Stable small particle liposome preparations, their production and use in topical cosmetic, and pharmaceutical compositions
CA2120197A1 (en) * 1993-04-02 1994-10-03 Kenji Endo Stable aqueous dispersions containing liposomes
JP3383704B2 (ja) * 1993-04-02 2003-03-04 わかもと製薬株式会社 安定なリポソーム水分散液
DE4341472A1 (de) * 1993-12-02 1995-06-08 Schering Ag Verfahren zur Erhöhung der Stabilität von hydrophile Wirkstoffe enthaltenden Liposomensuspensionen
DE4430593C2 (de) * 1994-08-20 1999-01-14 Max Delbrueck Centrum Verfahren zur Herstellung von Liposomal verkapseltem Taxol
US6132765A (en) * 1996-04-12 2000-10-17 Uroteq Inc. Drug delivery via therapeutic hydrogels
BR9709650A (pt) * 1996-06-04 1999-08-10 Procter & Gamble Aerosol nasal contendo um esteróide intransal e um anti-histamínico
JP4457422B2 (ja) * 1998-01-09 2010-04-28 大正製薬株式会社 点鼻組成物
US6726925B1 (en) * 1998-06-18 2004-04-27 Duke University Temperature-sensitive liposomal formulation
TR200101790T2 (tr) * 1998-12-23 2001-10-22 Idea Ag. Yayılgan olmayan in vivo topik uygulamalar için geliştirilmiş formül
US20030054030A1 (en) * 2001-09-13 2003-03-20 Gary Gordon Method and compositions for the treatment of pruritus
CN1599625A (zh) * 2001-12-05 2005-03-23 爱尔康公司 H1拮抗剂和安全类固醇治疗鼻炎的用途
WO2003097100A1 (en) * 2002-05-15 2003-11-27 Engelbrecht, Edna Topical composition for the treatment of inflammatory conditions of the skin
WO2004069338A1 (en) * 2003-01-31 2004-08-19 Schering Corporation Use of combinations of h1 and h3 histamine receptor antagonists for the preparation of a medicament for the treatment of allergic skin and allergic ocular conditions
JP2007522085A (ja) * 2003-06-27 2007-08-09 スミスクライン・ビーチャム・コーポレイション 安定化されたトポテカンリポソーム組成物および方法
US20050192261A1 (en) * 2003-09-15 2005-09-01 Jost-Price Edward R. Methods and reagents for the treatment of immunoinflammatory disorders
US20050112199A1 (en) * 2003-09-24 2005-05-26 Mahesh Padval Therapeutic regimens for administering drug combinations
US20080063699A1 (en) * 2003-10-15 2008-03-13 Michael Teifel Method of Administering Cationic Liposomes Comprising an Active Drug

Also Published As

Publication number Publication date
CA2616515A1 (en) 2007-03-08
SI1919450T1 (sl) 2014-10-30
WO2007026151A1 (en) 2007-03-08
EP1919450A1 (en) 2008-05-14
EP1919450B1 (en) 2014-06-11
JP5393151B2 (ja) 2014-01-22
ES2498795T3 (es) 2014-09-25
CN101257891A (zh) 2008-09-03
PL1919450T3 (pl) 2014-11-28
US20090324699A1 (en) 2009-12-31
CA2616515C (en) 2014-09-23
US20140065203A1 (en) 2014-03-06
HK1115314A1 (en) 2008-11-28
RU2444351C2 (ru) 2012-03-10
BRPI0615032A2 (pt) 2011-04-26
JP2009507009A (ja) 2009-02-19
RU2008112167A (ru) 2009-10-10
PT1919450E (pt) 2014-09-10

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