DK1915620T3 - Diagnose, behandling og prævention af vaskulære sygdomme ved hjælp af IL-1alpha-autoantistoffer - Google Patents
Diagnose, behandling og prævention af vaskulære sygdomme ved hjælp af IL-1alpha-autoantistofferInfo
- Publication number
- DK1915620T3 DK1915620T3 DK06795161.6T DK06795161T DK1915620T3 DK 1915620 T3 DK1915620 T3 DK 1915620T3 DK 06795161 T DK06795161 T DK 06795161T DK 1915620 T3 DK1915620 T3 DK 1915620T3
- Authority
- DK
- Denmark
- Prior art keywords
- autoantibodies
- vascular diseases
- 1alpha
- contraception
- diagnosis
- Prior art date
Links
- 208000019553 vascular disease Diseases 0.000 title abstract 3
- 238000003745 diagnosis Methods 0.000 title 1
- 201000001320 Atherosclerosis Diseases 0.000 abstract 2
- 108010002352 Interleukin-1 Proteins 0.000 abstract 2
- 238000001514 detection method Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Rehabilitation Therapy (AREA)
- Rheumatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US70445005P | 2005-08-02 | 2005-08-02 | |
PCT/IB2006/002038 WO2007015128A1 (en) | 2005-08-02 | 2006-07-26 | DIAGNOSIS, TREATMENT, AND PREVENTION OF VASCULAR DISORDERS USING IL-1α AUTOANTIBODIES |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1915620T3 true DK1915620T3 (da) | 2010-10-04 |
Family
ID=37442093
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK06795161.6T DK1915620T3 (da) | 2005-08-02 | 2006-07-26 | Diagnose, behandling og prævention af vaskulære sygdomme ved hjælp af IL-1alpha-autoantistoffer |
Country Status (11)
Country | Link |
---|---|
US (2) | US8187817B2 (da) |
EP (2) | EP1915620B1 (da) |
JP (2) | JP5645361B2 (da) |
CN (2) | CN101253409A (da) |
AT (1) | ATE470151T1 (da) |
AU (1) | AU2006274698B2 (da) |
CA (1) | CA2617637C (da) |
DE (1) | DE602006014691D1 (da) |
DK (1) | DK1915620T3 (da) |
ES (1) | ES2346691T3 (da) |
WO (1) | WO2007015128A1 (da) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
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CN101253409A (zh) * | 2005-08-02 | 2008-08-27 | 埃克斯生物科技公司 | 使用IL-1α自身抗体诊断、治疗和预防血管疾病 |
US20110008282A1 (en) * | 2006-05-15 | 2011-01-13 | Xbiotech, Inc. | IL-1alpha immunization induces autoantibodies protective against atherosclerosis |
ATE551365T1 (de) | 2006-05-15 | 2012-04-15 | Xbiotech Inc | Il-1-alpha für den einsatz in einem verfahren zur behandlung von atherosklerotischen plaques. |
WO2007135546A2 (en) * | 2006-05-22 | 2007-11-29 | Xbiotech Inc. | TREATMENT OF CANCER WITH ANTI-IL-1α ANTIBODIES |
MX2010012963A (es) | 2008-05-30 | 2011-04-05 | Xbiotech Inc | Anticuerpos de interleucina-1 alfa y metodos de uso. |
US8242074B2 (en) * | 2008-09-12 | 2012-08-14 | Xbiotech, Inc. | Modulation of the amount or function of pathogenic CD14+CD16+ monocytes |
EP2569640A1 (en) | 2010-05-12 | 2013-03-20 | The University of Birmingham | Biomarker |
MY161302A (en) | 2010-05-14 | 2017-04-14 | Abbvie Inc | IL-1 binding proteins |
AU2011268229B2 (en) | 2010-06-18 | 2015-04-16 | Xbiotech Inc. | Arthritis treatment |
KR102314003B1 (ko) | 2010-08-23 | 2021-10-19 | 얀센 바이오테크 인코포레이티드 | 종양성 질병들에 대한 치료 |
WO2012067165A1 (ja) * | 2010-11-17 | 2012-05-24 | 国立大学法人愛媛大学 | 自己免疫疾患に関与するタンパク質の解析方法及び該疾患の検査方法 |
US9724409B2 (en) | 2011-04-01 | 2017-08-08 | Xbiotech, Inc. | Treatment of inflammatory skin disease |
CN108404127A (zh) | 2011-09-23 | 2018-08-17 | 埃克斯生物科技公司 | 恶病质治疗 |
US9545441B2 (en) | 2012-09-18 | 2017-01-17 | Xbiotech, Inc. | Treatment of diabetes |
KR20190117579A (ko) | 2017-02-16 | 2019-10-16 | 엑스바이오테크, 인크. | 화농성 한선염의 치료 |
EP3761991A4 (en) * | 2018-03-09 | 2022-01-12 | The Brigham and Women's Hospital, Inc. | COMBINATION THERAPY FOR CARDIOVASCULAR DISEASES |
US10975146B2 (en) | 2018-06-29 | 2021-04-13 | Cedars-Sinai Medical Center | Interleukin-1 inhibition for combination treatment of pancreatic cancer |
KR20220019674A (ko) * | 2019-05-03 | 2022-02-17 | 유니베르시태트 취리히 | 뇌 허혈-재관류 손상의 치료 |
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ATE551365T1 (de) * | 2006-05-15 | 2012-04-15 | Xbiotech Inc | Il-1-alpha für den einsatz in einem verfahren zur behandlung von atherosklerotischen plaques. |
WO2007135546A2 (en) * | 2006-05-22 | 2007-11-29 | Xbiotech Inc. | TREATMENT OF CANCER WITH ANTI-IL-1α ANTIBODIES |
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-
2006
- 2006-07-26 CN CNA2006800319580A patent/CN101253409A/zh active Pending
- 2006-07-26 JP JP2008524607A patent/JP5645361B2/ja active Active
- 2006-07-26 CA CA2617637A patent/CA2617637C/en active Active
- 2006-07-26 EP EP06795161A patent/EP1915620B1/en active Active
- 2006-07-26 DK DK06795161.6T patent/DK1915620T3/da active
- 2006-07-26 EP EP10164642A patent/EP2216653A1/en not_active Withdrawn
- 2006-07-26 AT AT06795161T patent/ATE470151T1/de active
- 2006-07-26 DE DE602006014691T patent/DE602006014691D1/de active Active
- 2006-07-26 US US11/997,496 patent/US8187817B2/en active Active
- 2006-07-26 CN CN201811136397.1A patent/CN109187944A/zh active Pending
- 2006-07-26 WO PCT/IB2006/002038 patent/WO2007015128A1/en active Application Filing
- 2006-07-26 ES ES06795161T patent/ES2346691T3/es active Active
- 2006-07-26 AU AU2006274698A patent/AU2006274698B2/en active Active
-
2012
- 2012-05-17 US US13/473,939 patent/US8865175B2/en active Active
- 2012-12-27 JP JP2012283791A patent/JP5717256B2/ja active Active
Also Published As
Publication number | Publication date |
---|---|
DE602006014691D1 (de) | 2010-07-15 |
EP1915620A1 (en) | 2008-04-30 |
US8865175B2 (en) | 2014-10-21 |
CA2617637C (en) | 2017-07-18 |
US20120231012A1 (en) | 2012-09-13 |
CN101253409A (zh) | 2008-08-27 |
AU2006274698B2 (en) | 2011-06-09 |
JP5645361B2 (ja) | 2014-12-24 |
AU2006274698A2 (en) | 2008-03-06 |
EP1915620B1 (en) | 2010-06-02 |
EP2216653A1 (en) | 2010-08-11 |
JP5717256B2 (ja) | 2015-05-13 |
JP2013127469A (ja) | 2013-06-27 |
ATE470151T1 (de) | 2010-06-15 |
AU2006274698A1 (en) | 2007-02-08 |
ES2346691T3 (es) | 2010-10-19 |
JP2009503529A (ja) | 2009-01-29 |
US8187817B2 (en) | 2012-05-29 |
WO2007015128A1 (en) | 2007-02-08 |
CN109187944A (zh) | 2019-01-11 |
US20090123415A1 (en) | 2009-05-14 |
CA2617637A1 (en) | 2007-02-08 |
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