DK1893603T3 - Piperidin-4-YL-amidderivater og anvendelsen deraf som SST-receptorundertype 5-antagonister - Google Patents
Piperidin-4-YL-amidderivater og anvendelsen deraf som SST-receptorundertype 5-antagonisterInfo
- Publication number
- DK1893603T3 DK1893603T3 DK06755285T DK06755285T DK1893603T3 DK 1893603 T3 DK1893603 T3 DK 1893603T3 DK 06755285 T DK06755285 T DK 06755285T DK 06755285 T DK06755285 T DK 06755285T DK 1893603 T3 DK1893603 T3 DK 1893603T3
- Authority
- DK
- Denmark
- Prior art keywords
- piperidin
- antagonists
- receptor subtype
- amide derivatives
- sst receptor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4453—Non condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Nutrition Science (AREA)
- Child & Adolescent Psychology (AREA)
- Physical Education & Sports Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05104774 | 2005-06-02 | ||
PCT/EP2006/062515 WO2006128803A1 (en) | 2005-06-02 | 2006-05-23 | Piperidin-4-yl-amide derivatives and their use as sst receptor subtype 5 antagonists |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1893603T3 true DK1893603T3 (da) | 2009-11-30 |
Family
ID=36763959
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK06755285T DK1893603T3 (da) | 2005-06-02 | 2006-05-23 | Piperidin-4-YL-amidderivater og anvendelsen deraf som SST-receptorundertype 5-antagonister |
Country Status (22)
Country | Link |
---|---|
US (1) | US7772253B2 (da) |
EP (1) | EP1893603B1 (da) |
JP (1) | JP4949387B2 (da) |
KR (1) | KR100962732B1 (da) |
CN (1) | CN101189226A (da) |
AR (1) | AR054277A1 (da) |
AT (1) | ATE445612T1 (da) |
AU (1) | AU2006254256B2 (da) |
BR (1) | BRPI0611138A2 (da) |
CA (1) | CA2608819A1 (da) |
DE (1) | DE602006009804D1 (da) |
DK (1) | DK1893603T3 (da) |
ES (1) | ES2330788T3 (da) |
IL (1) | IL187426A (da) |
MX (1) | MX2007014928A (da) |
NO (1) | NO20076060L (da) |
PL (1) | PL1893603T3 (da) |
PT (1) | PT1893603E (da) |
RU (1) | RU2403250C2 (da) |
TW (1) | TWI315305B (da) |
WO (1) | WO2006128803A1 (da) |
ZA (1) | ZA200710169B (da) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7799806B2 (en) | 2007-04-04 | 2010-09-21 | Hoffmann-La Roche Inc. | Substituted n-benzyl piperidines as somatostatin receptor modulators |
US8026365B2 (en) * | 2007-05-25 | 2011-09-27 | Hoffman-La Roche Inc. | 4,4-disubstituted piperidine derivatives |
WO2011048525A1 (en) * | 2009-10-20 | 2011-04-28 | Pfizer Inc. | Novel heteroaryl imidazoles and heteroaryl triazoles as gamma-secretase modulators |
US8999889B2 (en) | 2010-02-01 | 2015-04-07 | Basf Se | Substituted ketonic isoxazoline compounds and derivatives for combating animal pests |
US8742110B2 (en) | 2010-08-18 | 2014-06-03 | Merck Sharp & Dohme Corp. | Spiroxazolidinone compounds |
BR112013007038A2 (pt) | 2010-10-01 | 2019-09-24 | Basf Se | "derivados de 2,4-diaril-pirrolina substituída por imina como pesticidas" |
WO2012042006A1 (en) | 2010-10-01 | 2012-04-05 | Basf Se | Imine compounds |
TWI834637B (zh) | 2018-03-01 | 2024-03-11 | 日商武田藥品工業有限公司 | 六氫吡啶基-3-(芳氧基)丙醯胺及丙酸酯 |
BR112022006546A2 (pt) | 2019-10-07 | 2022-08-30 | Kallyope Inc | Agonistas de gpr119 |
EP4110788A4 (en) | 2020-02-28 | 2024-08-28 | Kallyope, Inc. | Gpr40 agonists |
JP7553547B2 (ja) | 2020-03-31 | 2024-09-18 | エヌ・イーケムキャット株式会社 | 芳香族化合物の製造方法 |
JP2023526625A (ja) | 2020-05-19 | 2023-06-22 | キャリーオペ,インク. | Ampkアクチベーター |
CA3183575A1 (en) | 2020-06-26 | 2021-12-30 | Iyassu Sebhat | Ampk activators |
CN115215787A (zh) * | 2021-04-19 | 2022-10-21 | 中国科学院上海药物研究所 | 生长抑素受体5拮抗剂及其用途 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH598231A5 (da) | 1973-07-27 | 1978-04-28 | Hoffmann La Roche | |
AR216043A1 (es) * | 1974-03-21 | 1979-11-30 | Anphar Sa | Procedimiento para la preparacion de 1-derivados de benzoilamino-4-piperidina y sus sales fisiologicamente aceptables |
GB1574418A (en) * | 1976-11-16 | 1980-09-03 | Anphar Sa | Piperidine derivatives |
CH628885A5 (en) * | 1978-01-01 | 1982-03-31 | Anphar Sa | Piperidine derivative |
JPS5592384A (en) * | 1978-12-30 | 1980-07-12 | Beecham Group Ltd | Compound having pharmacological activity |
US5098915A (en) * | 1989-09-05 | 1992-03-24 | G. D. Searle & Co. | Substituted N-benzylpiperidine amides |
SE9702794D0 (sv) | 1997-07-24 | 1997-07-24 | Astra Pharma Prod | New compounds |
TR200103214T2 (tr) | 1999-05-04 | 2002-03-21 | Schering Corporation | CCR5 antagonistleri olarak yararlì piperazin trevleri. |
US6344358B1 (en) * | 1999-05-28 | 2002-02-05 | Fujisawa Pharmaceutical Co., Ltd. | Agent for expression of long-term potentiation of synaptic transmission comprising compound having brain somatostatin activation property |
FR2802206B1 (fr) | 1999-12-14 | 2005-04-22 | Sod Conseils Rech Applic | Derives de 4-aminopiperidine et leur utilisation en tant que medicament |
DK1638933T3 (da) * | 2003-06-17 | 2008-07-28 | Pfizer | N-pyrrolidin-3-yl-amid-derivater som serotonin- og noradrenalin-genoptagelses inhibitorer |
JP4745244B2 (ja) | 2003-11-05 | 2011-08-10 | エフ.ホフマン−ラ ロシュ アーゲー | Pparアゴニストとしてのフェニル誘導体 |
-
2006
- 2006-05-23 ES ES06755285T patent/ES2330788T3/es active Active
- 2006-05-23 PL PL06755285T patent/PL1893603T3/pl unknown
- 2006-05-23 KR KR1020077028019A patent/KR100962732B1/ko not_active Expired - Fee Related
- 2006-05-23 WO PCT/EP2006/062515 patent/WO2006128803A1/en active Application Filing
- 2006-05-23 RU RU2007148224/04A patent/RU2403250C2/ru not_active IP Right Cessation
- 2006-05-23 AT AT06755285T patent/ATE445612T1/de active
- 2006-05-23 DK DK06755285T patent/DK1893603T3/da active
- 2006-05-23 CA CA002608819A patent/CA2608819A1/en not_active Abandoned
- 2006-05-23 BR BRPI0611138-6A patent/BRPI0611138A2/pt not_active IP Right Cessation
- 2006-05-23 EP EP06755285A patent/EP1893603B1/en not_active Not-in-force
- 2006-05-23 CN CNA2006800194138A patent/CN101189226A/zh active Pending
- 2006-05-23 MX MX2007014928A patent/MX2007014928A/es active IP Right Grant
- 2006-05-23 PT PT06755285T patent/PT1893603E/pt unknown
- 2006-05-23 DE DE602006009804T patent/DE602006009804D1/de active Active
- 2006-05-23 AU AU2006254256A patent/AU2006254256B2/en not_active Ceased
- 2006-05-23 JP JP2008514062A patent/JP4949387B2/ja not_active Expired - Fee Related
- 2006-05-26 US US11/442,619 patent/US7772253B2/en not_active Expired - Fee Related
- 2006-05-30 TW TW095119084A patent/TWI315305B/zh not_active IP Right Cessation
- 2006-05-31 AR AR20060102259A patent/AR054277A1/es not_active Application Discontinuation
-
2007
- 2007-11-15 IL IL187426A patent/IL187426A/en not_active IP Right Cessation
- 2007-11-26 NO NO20076060A patent/NO20076060L/no not_active Application Discontinuation
- 2007-11-26 ZA ZA200710169A patent/ZA200710169B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
US7772253B2 (en) | 2010-08-10 |
BRPI0611138A2 (pt) | 2010-08-17 |
PL1893603T3 (pl) | 2010-03-31 |
JP2008545730A (ja) | 2008-12-18 |
KR100962732B1 (ko) | 2010-06-09 |
US20060276508A1 (en) | 2006-12-07 |
RU2403250C2 (ru) | 2010-11-10 |
JP4949387B2 (ja) | 2012-06-06 |
TW200716547A (en) | 2007-05-01 |
NO20076060L (no) | 2007-12-28 |
KR20080008391A (ko) | 2008-01-23 |
AU2006254256B2 (en) | 2012-04-12 |
ES2330788T3 (es) | 2009-12-15 |
RU2007148224A (ru) | 2009-07-20 |
PT1893603E (pt) | 2009-11-24 |
DE602006009804D1 (de) | 2009-11-26 |
AU2006254256A1 (en) | 2006-12-07 |
EP1893603A1 (en) | 2008-03-05 |
IL187426A (en) | 2011-10-31 |
AR054277A1 (es) | 2007-06-13 |
EP1893603B1 (en) | 2009-10-14 |
ZA200710169B (en) | 2008-12-31 |
CN101189226A (zh) | 2008-05-28 |
ATE445612T1 (de) | 2009-10-15 |
CA2608819A1 (en) | 2006-12-07 |
IL187426A0 (en) | 2008-02-09 |
MX2007014928A (es) | 2008-02-15 |
WO2006128803A1 (en) | 2006-12-07 |
TWI315305B (en) | 2009-10-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK1893603T3 (da) | Piperidin-4-YL-amidderivater og anvendelsen deraf som SST-receptorundertype 5-antagonister | |
DK1718641T3 (da) | Benzimidazolderivat og dets anvendelse som All-receptorantagonist | |
DK1723116T3 (da) | Tetrahydroquinolinoner og deres anvendelse som antagonister for metabotropiske glutamatreceptorer | |
DK1951660T3 (da) | Histamin-3-receptorantagonister | |
DK1725540T5 (da) | Diaminopyrimidiner som p2x3- og p2x2/3-antagonister | |
NL300690I2 (nl) | Lurasidon hydrochloride | |
DK2049478T3 (da) | Substituerede N-phenylmethyl-5-oxoprolin-2-amider som P2X7-receptorantagonister og fremgangsmåder til anvendelse deraf | |
KR101500766B9 (ko) | 치환된 3-이소부틸-9,10-디메톡시-1,3,4,6,7,11b-헥사히드로-2H-피리도[2,1-a]이소퀴놀린-2-올 화합물 및 그와 관련된 방법 | |
DK1973886T3 (da) | Prokineticin-1-receptor-antagonister | |
ATE505467T1 (de) | 2-aza-bicycloä3.1.0ühexanderivate als orexin- rezeptorantagonisten | |
EP2049110A4 (en) | BRAZED DIAZEPANOREXINE RECEPTOR ANTAGONISTS | |
EP1959959A4 (en) | MORPHOLIN-CARBOXAMIDE PROKINETICIN RECEPTOR ANTAGONISTS | |
MA28571B1 (fr) | Methyl-aryl-ou heteroaryl-amides substitues | |
ATE495167T1 (de) | Piperidin-4-yl-pyridazin-3-yl-aminderivate als schnell dissoziierende antagonisten des dopamin-2-rezeptors | |
ZA200709147B (en) | Pyrimidindione derivatives as prokineticin 2 receptor antagonists | |
DE602005027307D1 (de) | Arylanilinderivate als agonisten des beta2-adrenergen rezeptors | |
DK1928821T3 (da) | Carboxamidderivater som muscarinreceptorantagonister | |
ATE421511T1 (de) | Indol-3-carbonyl-spiro-piperidinderivate als antagonisten des v1a-rezeptors | |
IL178461A0 (en) | Substituted 4-alkyl -and 4-alkanoyl-piperidine derivatives and their use as neurokinin antagonists | |
IL205608A0 (en) | Triazole -substituted arylamide derivatives and their use as p2x3 and/or p2x2/3purinergic receptor antagonists | |
DK1856051T3 (da) | Amorft lercanidipinhydrochlorid | |
DK1711465T3 (da) | Hydroisoindolin-tachykinikreceptorantagonister | |
DK2121630T3 (da) | Hurtigt dissocierende dopamin-2-receptor-antagonister | |
ATE500227T1 (de) | Amidderivate | |
DK1581518T3 (da) | Substituerede 1-piperidin-4-yl-4-pyrrolidin-3-yl-piperazin-derivater og deres anvendelse som neurokinin antagonister |