DK1791860T3 - Oprensningsfremgangsmåde for bakterielt cytolysin - Google Patents
Oprensningsfremgangsmåde for bakterielt cytolysinInfo
- Publication number
- DK1791860T3 DK1791860T3 DK05797390T DK05797390T DK1791860T3 DK 1791860 T3 DK1791860 T3 DK 1791860T3 DK 05797390 T DK05797390 T DK 05797390T DK 05797390 T DK05797390 T DK 05797390T DK 1791860 T3 DK1791860 T3 DK 1791860T3
- Authority
- DK
- Denmark
- Prior art keywords
- bacterial cytolysin
- salt
- extract
- purification procedure
- bacterial
- Prior art date
Links
- 102000004503 Perforin Human genes 0.000 title abstract 5
- 108010056995 Perforin Proteins 0.000 title abstract 5
- 230000001580 bacterial effect Effects 0.000 title abstract 5
- 238000000746 purification Methods 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 abstract 4
- 239000003599 detergent Substances 0.000 abstract 2
- 238000004191 hydrophobic interaction chromatography Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
- C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
- C07K1/1136—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by reversible modification of the secondary, tertiary or quarternary structure, e.g. using denaturating or stabilising agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6087—Polysaccharides; Lipopolysaccharides [LPS]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Separation Of Suspended Particles By Flocculating Agents (AREA)
- Detergent Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0421083.7A GB0421083D0 (en) | 2004-09-22 | 2004-09-22 | Purification process |
| PCT/EP2005/010258 WO2006032499A1 (en) | 2004-09-22 | 2005-09-20 | Purification process for bacterial cytolysin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1791860T3 true DK1791860T3 (da) | 2008-07-14 |
Family
ID=33397075
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK05797390T DK1791860T3 (da) | 2004-09-22 | 2005-09-20 | Oprensningsfremgangsmåde for bakterielt cytolysin |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20070231876A1 (da) |
| EP (1) | EP1791860B1 (da) |
| JP (1) | JP4934591B2 (da) |
| AT (1) | ATE393165T1 (da) |
| CA (1) | CA2580113C (da) |
| CY (1) | CY1107960T1 (da) |
| DE (1) | DE602005006294T2 (da) |
| DK (1) | DK1791860T3 (da) |
| ES (1) | ES2304724T3 (da) |
| GB (1) | GB0421083D0 (da) |
| HR (1) | HRP20080242T3 (da) |
| PL (1) | PL1791860T3 (da) |
| PT (1) | PT1791860E (da) |
| SI (1) | SI1791860T1 (da) |
| WO (1) | WO2006032499A1 (da) |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2340627C2 (ru) | 2003-03-13 | 2008-12-10 | ГлаксоСмитКлайн Байолоджикалз с.а. | Способ очистки бактериального цитолизина |
| EP3470080A1 (en) | 2005-12-22 | 2019-04-17 | GlaxoSmithKline Biologicals S.A. | Vaccine comprising streptococcus pneumoniae capsular polysaccharide conjugates |
| GB0607088D0 (en) | 2006-04-07 | 2006-05-17 | Glaxosmithkline Biolog Sa | Vaccine |
| AU2007281044A1 (en) * | 2006-08-03 | 2008-02-07 | Newcastle Innovation Limited | Treatment and prevention of allergic airways diseases |
| MX2009013949A (es) | 2007-06-26 | 2010-05-24 | Glaxosmithkline Biolog Sa | Vacuna que comprende conjugados de polisacárido capsular de streptococcus pneumoniae. |
| AU2009208403A1 (en) | 2008-02-01 | 2009-08-06 | Newcastle Innovation Limited | Vaccine compositions |
| PE20121544A1 (es) | 2009-09-03 | 2012-12-02 | Pfizer Vaccines Llc | Vacuna de pcsk9 |
| WO2012127485A1 (en) * | 2011-03-22 | 2012-09-27 | Serum Institute Of India Ltd. | A novel process for preparation of polysaccharides |
| HUE047085T2 (hu) * | 2011-04-22 | 2020-04-28 | Wyeth Llc | Clostridium difficile mutáns toxinjához kapcsolódó készítmények és eljárásai |
| MX339058B (es) | 2011-05-17 | 2016-05-09 | Glaxosmithkline Biolog Sa | Vacuna contra streptococcus pneumoniae. |
| US11160855B2 (en) | 2014-01-21 | 2021-11-02 | Pfizer Inc. | Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof |
| NZ755770A (en) | 2014-01-21 | 2023-06-30 | Pfizer | Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof |
| US9815886B2 (en) | 2014-10-28 | 2017-11-14 | Adma Biologics, Inc. | Compositions and methods for the treatment of immunodeficiency |
| FI3244917T3 (fi) | 2015-01-15 | 2023-05-25 | Pfizer | Immunogeenisiä koostumuksia pneumokokkirokotteissa käytettäväksi |
| PE20180657A1 (es) | 2015-07-21 | 2018-04-17 | Pfizer | Composiciones inmunogenas que comprenden antigenos de sacarido capsular conjugados, kits que las comprenden y sus usos |
| JP6884145B2 (ja) | 2015-11-20 | 2021-06-09 | ファイザー・インク | 肺炎連鎖球菌ワクチンにおいて用いるための免疫原性組成物 |
| GB201603029D0 (en) * | 2016-02-22 | 2016-04-06 | Glaxosmithkline Biolog Sa | Vaccine |
| EP3493837B1 (en) | 2016-08-05 | 2022-08-31 | Sanofi Pasteur, Inc. | Multivalent pneumococcal polysaccharide-protein conjugate composition |
| EP3493840B1 (en) | 2016-08-05 | 2022-08-24 | Sanofi Pasteur Inc. | Multivalent pneumococcal polysaccharide-protein conjugate composition |
| CN110366428B (zh) | 2016-12-30 | 2024-05-17 | Vaxcyte公司 | 具有非天然氨基酸的多肽-抗原缀合物 |
| US11951165B2 (en) | 2016-12-30 | 2024-04-09 | Vaxcyte, Inc. | Conjugated vaccine carrier proteins |
| DK3570879T3 (da) | 2017-01-20 | 2022-04-11 | Pfizer | Immunogene sammensætninger til anvendelse i pneumokokvacciner |
| US10259865B2 (en) | 2017-03-15 | 2019-04-16 | Adma Biologics, Inc. | Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection |
| WO2019152925A1 (en) | 2018-02-05 | 2019-08-08 | Sanofi Pasteur Inc. | Multivalent pneumococcal polysaccharide-protein conjugate composition |
| MX2020007939A (es) | 2018-02-05 | 2020-09-03 | Sanofi Pasteur Inc | Composicion del conjugado proteina-polisacarido multivalente nuemococica. |
| JP2021522213A (ja) | 2018-04-18 | 2021-08-30 | エスケー バイオサイエンス カンパニー リミテッド | ストレプトコッカス・ニューモニエ莢膜多糖類及びその免疫原性接合体 |
| GB201807303D0 (en) | 2018-05-03 | 2018-06-20 | London School Of Hygeine & Tropical Medicine | Glyconjugate vaccines |
| US11260119B2 (en) | 2018-08-24 | 2022-03-01 | Pfizer Inc. | Escherichia coli compositions and methods thereof |
| CA3120922A1 (en) | 2018-12-12 | 2020-06-18 | Pfizer Inc. | Immunogenic multiple hetero-antigen polysaccharide-protein conjugates and uses thereof |
| JP7551618B2 (ja) | 2018-12-12 | 2024-09-17 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | Ｏ－結合型グリコシル化のための修飾キャリアタンパク質 |
| JP7239509B6 (ja) | 2019-02-22 | 2023-03-28 | ファイザー・インク | 細菌多糖類を精製するための方法 |
| EP3952906A1 (en) | 2019-04-10 | 2022-02-16 | Pfizer Inc. | Immunogenic compositions comprising conjugated capsular saccharide antigens, kits comprising the same and uses thereof |
| MX2022001241A (es) | 2019-07-31 | 2022-04-20 | Sanofi Pasteur Inc | Composiciones de conjugados neumococicos multivalentes polisacarido - proteina y metodos para usar los mismos. |
| CA3171864A1 (en) | 2020-02-21 | 2021-08-26 | Pfizer Inc. | Purification of saccharides |
| WO2022084852A1 (en) | 2020-10-22 | 2022-04-28 | Pfizer Inc. | Methods for purifying bacterial polysaccharides |
| US12138302B2 (en) | 2020-10-27 | 2024-11-12 | Pfizer Inc. | Escherichia coli compositions and methods thereof |
| CA3200602A1 (en) | 2020-11-04 | 2022-05-12 | Pfizer Inc. | Immunogenic compositions for use in pneumococcal vaccines |
| EP4333879A1 (en) | 2021-05-03 | 2024-03-13 | Pfizer Inc. | Vaccination against bacterial and betacoronavirus infections |
| WO2022234416A1 (en) | 2021-05-03 | 2022-11-10 | Pfizer Inc. | Vaccination against pneumoccocal and covid-19 infections |
| TW202306969A (zh) | 2021-05-28 | 2023-02-16 | 美商輝瑞大藥廠 | 包含結合之莢膜醣抗原的免疫原組合物及其用途 |
| MX2023013434A (es) | 2021-05-28 | 2023-12-12 | Pfizer | Composiciones inmunogenas que comprenden antigenos de sacarido capsular conjugados y sus usos. |
| CN118510548A (zh) | 2022-01-13 | 2024-08-16 | 辉瑞公司 | 包含缀合的荚膜糖抗原的免疫原性组合物及其用途 |
| WO2023161817A1 (en) | 2022-02-25 | 2023-08-31 | Pfizer Inc. | Methods for incorporating azido groups in bacterial capsular polysaccharides |
| CN119317445A (zh) | 2022-05-11 | 2025-01-14 | 辉瑞公司 | 用于生产含有防腐剂的疫苗制剂的方法 |
| WO2024084397A1 (en) | 2022-10-19 | 2024-04-25 | Pfizer Inc. | Vaccination against pneumoccocal and covid-19 infections |
| WO2024110827A1 (en) | 2022-11-21 | 2024-05-30 | Pfizer Inc. | Methods for preparing conjugated capsular saccharide antigens and uses thereof |
| US20240181028A1 (en) | 2022-11-22 | 2024-06-06 | Pfizer Inc. | Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof |
| WO2024116096A1 (en) | 2022-12-01 | 2024-06-06 | Pfizer Inc. | Pneumococcal conjugate vaccine formulations |
| WO2024166008A1 (en) | 2023-02-10 | 2024-08-15 | Pfizer Inc. | Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof |
| WO2024201324A2 (en) | 2023-03-30 | 2024-10-03 | Pfizer Inc. | Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof |
| WO2024214016A1 (en) | 2023-04-14 | 2024-10-17 | Pfizer Inc. | Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof |
| WO2024224266A1 (en) | 2023-04-24 | 2024-10-31 | Pfizer Inc. | Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof |
| WO2024241172A2 (en) | 2023-05-19 | 2024-11-28 | Glaxosmithkline Biologicals Sa | Methods for eliciting an immune response to respiratory syncycial virus and streptococcus pneumoniae infection |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2121481C1 (ru) * | 1988-12-16 | 1998-11-10 | Де Стат Дер Недерланден Вертегенвордигд Дор де Министр Ван Велзейн, Волксгезондхейд эн Кюлтюр | Модифицированный пневмолизин, рекомбинантная плазмида, способ получения модифицированного пневмолизина, вакцина |
| DE4133707A1 (de) * | 1991-10-11 | 1993-04-15 | Behringwerke Ag | Verfahren zur reinigung von streptolysin o, intaktes streptolysin o erhaeltlich nach diesem verfahren und seine verwendung |
| US5652125A (en) * | 1996-06-10 | 1997-07-29 | Pharmacia S.P.A. | Process for preparing daunorubicin |
| HUP0002475A3 (en) * | 1997-07-21 | 2002-01-28 | Baxter Healthcare S A Wallisel | Modified immunogenic pneumolysin compositions as vaccines |
| RU2340627C2 (ru) * | 2003-03-13 | 2008-12-10 | ГлаксоСмитКлайн Байолоджикалз с.а. | Способ очистки бактериального цитолизина |
| JP4578067B2 (ja) * | 2003-06-06 | 2010-11-10 | 宏 清水 | 局所医薬組成物 |
-
2004
- 2004-09-22 GB GBGB0421083.7A patent/GB0421083D0/en not_active Ceased
-
2005
- 2005-09-20 PL PL05797390T patent/PL1791860T3/pl unknown
- 2005-09-20 EP EP05797390A patent/EP1791860B1/en active Active
- 2005-09-20 PT PT05797390T patent/PT1791860E/pt unknown
- 2005-09-20 DE DE602005006294T patent/DE602005006294T2/de active Active
- 2005-09-20 AT AT05797390T patent/ATE393165T1/de active
- 2005-09-20 WO PCT/EP2005/010258 patent/WO2006032499A1/en active IP Right Grant
- 2005-09-20 US US11/575,676 patent/US20070231876A1/en not_active Abandoned
- 2005-09-20 JP JP2007531717A patent/JP4934591B2/ja not_active Expired - Fee Related
- 2005-09-20 ES ES05797390T patent/ES2304724T3/es active Active
- 2005-09-20 CA CA2580113A patent/CA2580113C/en not_active Expired - Fee Related
- 2005-09-20 DK DK05797390T patent/DK1791860T3/da active
- 2005-09-20 SI SI200530269T patent/SI1791860T1/sl unknown
-
2008
- 2008-05-26 CY CY20081100535T patent/CY1107960T1/el unknown
- 2008-06-02 HR HR20080242T patent/HRP20080242T3/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2580113A1 (en) | 2006-03-30 |
| ATE393165T1 (de) | 2008-05-15 |
| WO2006032499A1 (en) | 2006-03-30 |
| EP1791860A1 (en) | 2007-06-06 |
| GB0421083D0 (en) | 2004-10-27 |
| SI1791860T1 (sl) | 2008-08-31 |
| US20070231876A1 (en) | 2007-10-04 |
| CY1107960T1 (el) | 2013-09-04 |
| JP4934591B2 (ja) | 2012-05-16 |
| EP1791860B1 (en) | 2008-04-23 |
| PL1791860T3 (pl) | 2008-09-30 |
| DE602005006294T2 (de) | 2008-08-14 |
| PT1791860E (pt) | 2008-05-20 |
| ES2304724T3 (es) | 2008-10-16 |
| JP2008513408A (ja) | 2008-05-01 |
| CA2580113C (en) | 2018-01-16 |
| DE602005006294D1 (de) | 2008-06-05 |
| HRP20080242T3 (en) | 2008-09-30 |
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