DK178180A - Fremgangsmaade til frmstilling af 3-(hydroxyethyl) azetidiononer - Google Patents
Fremgangsmaade til frmstilling af 3-(hydroxyethyl) azetidiononerInfo
- Publication number
- DK178180A DK178180A DK178180A DK178180A DK178180A DK 178180 A DK178180 A DK 178180A DK 178180 A DK178180 A DK 178180A DK 178180 A DK178180 A DK 178180A DK 178180 A DK178180 A DK 178180A
- Authority
- DK
- Denmark
- Prior art keywords
- hydroxyethyl
- azetidionones
- preparing
- thienamycin
- azetidinones
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 125000000954 2-hydroxyethyl group Chemical class [H]C([*])([H])C([H])([H])O[H] 0.000 title 1
- UMHGAVAUBIVOAL-UHFFFAOYSA-N 3-(1-hydroxyethyl)azetidin-2-one Chemical class CC(O)C1CNC1=O UMHGAVAUBIVOAL-UHFFFAOYSA-N 0.000 abstract 1
- WKDDRNSBRWANNC-ATRFCDNQSA-N Thienamycin Chemical compound C1C(SCCN)=C(C(O)=O)N2C(=O)[C@H]([C@H](O)C)[C@H]21 WKDDRNSBRWANNC-ATRFCDNQSA-N 0.000 abstract 1
- WKDDRNSBRWANNC-UHFFFAOYSA-N Thienamycin Natural products C1C(SCCN)=C(C(O)=O)N2C(=O)C(C(O)C)C21 WKDDRNSBRWANNC-UHFFFAOYSA-N 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3405379A | 1979-04-27 | 1979-04-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK178180A true DK178180A (da) | 1980-10-28 |
Family
ID=21874008
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK178180A DK178180A (da) | 1979-04-27 | 1980-04-25 | Fremgangsmaade til frmstilling af 3-(hydroxyethyl) azetidiononer |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0018594B1 (da) |
| JP (1) | JPS56108785A (da) |
| AT (1) | ATE15039T1 (da) |
| DE (1) | DE3071008D1 (da) |
| DK (1) | DK178180A (da) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4446146A (en) * | 1978-07-26 | 1984-05-01 | Beecham Group Limited | β-Lactam containing compounds, their preparation and use |
| PT71552B (en) * | 1979-07-23 | 1981-12-14 | Merck & Co Inc | Process for preparation of thienamycin and intermediates |
| JPS57167964A (en) * | 1981-04-09 | 1982-10-16 | Toyama Chem Co Ltd | Preparation of (4r)-3-substituted-4-(substituted or unsubstituted carboxymethyl)-2-azetidinone derivative |
| DE3269313D1 (en) * | 1981-05-14 | 1986-04-03 | Beecham Group Plc | Process for the preparation of an enantiomer of a beta-lactam derivative |
| JPS58103358A (ja) * | 1981-10-23 | 1983-06-20 | メルク・エンド・カムパニ−・インコ−ポレ−テツド | 抗生物質中間体の製造方法 |
| HU184494B (en) * | 1981-12-30 | 1984-08-28 | Richter Gedeon Vegyeszet | Process for producing new azetidinone-caraoxylic acids |
| HU185081B (en) * | 1981-12-30 | 1984-11-28 | Richter Gedeon Vegyeszet | Process for preparing azetidinone-acetic acid derivatives |
| EP0180189B1 (en) * | 1984-10-31 | 1991-01-23 | Sumitomo Pharmaceuticals Company, Limited | Novel beta-lactams and their production |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7712093A (nl) * | 1976-11-19 | 1978-05-23 | Merck & Co Inc | Werkwijze voor het bereiden van isomere thienamycinen. |
| GB1593524A (en) * | 1976-11-19 | 1981-07-15 | Merck & Co Inc | 1-carba-2-penem-3-carboxylic acids |
| US4174316A (en) * | 1978-08-14 | 1979-11-13 | Merck & Co., Inc. | 4-Iodomethylazetidin-2-one |
| EP0017992A1 (en) * | 1979-04-19 | 1980-10-29 | Merck & Co. Inc. | 2-Substituted-6-substituted-1-carbadethiapen-2-em-3-carboxylic acids, processes for preparing them, antibiotic pharmaceutical compositions containing same and process for preparing intermediates |
| PT71552B (en) * | 1979-07-23 | 1981-12-14 | Merck & Co Inc | Process for preparation of thienamycin and intermediates |
| US4262010A (en) * | 1979-12-03 | 1981-04-14 | Merck & Co., Inc. | 6-(1-Hydroxyethyl)-2-(2-aminoethylthio)-1,1-disubstituted-1-carbadethiapen-2-em-3-carboxylic acids |
| GR72296B (da) * | 1979-12-03 | 1983-10-18 | Merck & Co Inc | |
| DE3169321D1 (en) * | 1980-03-27 | 1985-04-25 | Merck & Co Inc | Process for the preparation of 1-carbapenems and intermediates via silyl-substituted dithioacetals |
| IE52147B1 (en) * | 1980-03-27 | 1987-07-08 | Merck & Co Inc | 4-(3-carboxy-2-oxopropyl)-azetidin-2-ones and process for their preparation |
-
1980
- 1980-04-24 EP EP80102202A patent/EP0018594B1/en not_active Expired
- 1980-04-24 AT AT80102202T patent/ATE15039T1/de not_active IP Right Cessation
- 1980-04-24 DE DE8080102202T patent/DE3071008D1/de not_active Expired
- 1980-04-25 DK DK178180A patent/DK178180A/da not_active Application Discontinuation
- 1980-04-28 JP JP5554680A patent/JPS56108785A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP0018594A2 (en) | 1980-11-12 |
| DE3071008D1 (en) | 1985-09-26 |
| ATE15039T1 (de) | 1985-09-15 |
| EP0018594B1 (en) | 1985-08-21 |
| EP0018594A3 (en) | 1981-01-07 |
| JPS56108785A (en) | 1981-08-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment |