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DK177284A - Fremgangsmaade til fremstilling af substituerede aromatiske aminer - Google Patents

Fremgangsmaade til fremstilling af substituerede aromatiske aminer Download PDF

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Publication number
DK177284A
DK177284A DK177284A DK177284A DK177284A DK 177284 A DK177284 A DK 177284A DK 177284 A DK177284 A DK 177284A DK 177284 A DK177284 A DK 177284A DK 177284 A DK177284 A DK 177284A
Authority
DK
Denmark
Prior art keywords
procedure
substituted aromatic
aromatic amines
preparing substituted
preparing
Prior art date
Application number
DK177284A
Other languages
English (en)
Other versions
DK177284D0 (da
Inventor
Brian Michael Adger
Maria Aleksandra Wilczynska
Original Assignee
Smith Kline French Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838319876A external-priority patent/GB8319876D0/en
Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab
Publication of DK177284D0 publication Critical patent/DK177284D0/da
Publication of DK177284A publication Critical patent/DK177284A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/44—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers
    • C07C209/48—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers by reduction of nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Description

X er en C-^-alkylengruppe eller en C2_5-alkenylengruppef ved (a) omsætning af en forbindelse med formlen (6): N02-AX-CN (6) hvori A og X har den i forbindelse med formlen (5) definerede betydning, med hydrazin i nærværelse af en overgangsmetal-katalysator til dannelse af en forbindelse med formlen (7): NH2-AX-CN (7) hvori A og X har den i forbindelse med formlen (5) definerede betydning, og derefter (b) omsætning af den således opnåede forbindelse med formlen (7) med mere hydrazin og Raney-nikkel.
DK177284A 1983-04-07 1984-04-03 Fremgangsmaade til fremstilling af substituerede aromatiske aminer DK177284A (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB8309481 1983-04-07
GB8309481 1983-04-07
GB838319876A GB8319876D0 (en) 1983-07-23 1983-07-23 Chemical process
GB8319876 1983-07-23

Publications (2)

Publication Number Publication Date
DK177284D0 DK177284D0 (da) 1984-04-03
DK177284A true DK177284A (da) 1984-10-08

Family

ID=26285759

Family Applications (1)

Application Number Title Priority Date Filing Date
DK177284A DK177284A (da) 1983-04-07 1984-04-03 Fremgangsmaade til fremstilling af substituerede aromatiske aminer

Country Status (6)

Country Link
EP (1) EP0122109A3 (da)
AU (1) AU562383B2 (da)
DK (1) DK177284A (da)
ES (1) ES531341A0 (da)
GR (1) GR79892B (da)
PT (1) PT78358B (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0707764A2 (pt) 2006-02-13 2011-05-10 Hofemann La Roche Ag F compostos, processo para a sua manufatura, composiÇÕes farmacÊuticas que contÊm, mÉtodo para o tratamento terapÊutico e / ou profilÁtico de enfermidades que sço moduladas por inibidores de l-cpt1 e usos dos compostos

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU51945A1 (da) * 1965-09-18 1966-11-14
DE1920635C3 (de) * 1969-04-19 1979-06-28 Schering Ag, 1000 Berlin Und 4619 Bergkamen 2-(l-MethyI-5-nitro-2-imidazolyl)benzimidazole
AT327918B (de) * 1973-04-27 1976-02-25 Degussa Verfahren zur herstellung von neuen 6-aza-3h-1,4-benzodiazepinen und deren salzen
NZ197998A (en) * 1980-08-12 1985-08-16 Glaxo Group Ltd 5-amino(methyl)-1h-indol-3-ylalkaneamines
JO1274B1 (en) * 1982-12-03 1985-04-20 سيدني ساخ جورج Pyridine derivatives
AU2222083A (en) * 1982-12-14 1984-06-21 Smith Kline & French Laboratories Limited Pyridine derivatives
GB8319874D0 (en) * 1983-07-23 1983-08-24 Smith Kline French Lab Compounds

Also Published As

Publication number Publication date
PT78358A (en) 1984-05-01
EP0122109A3 (en) 1986-03-12
DK177284D0 (da) 1984-04-03
PT78358B (en) 1986-05-30
AU2644884A (en) 1984-10-11
ES8601851A1 (es) 1985-11-16
AU562383B2 (en) 1987-06-11
EP0122109A2 (en) 1984-10-17
ES531341A0 (es) 1985-11-16
GR79892B (da) 1984-10-31

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment