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DK174978B1 - Anvendelse af human koagulationsfaktor XIII til fremstilling af et lægemiddel til hindring af intraventrikulær blødning hos for tidligt fødte børn - Google Patents

Anvendelse af human koagulationsfaktor XIII til fremstilling af et lægemiddel til hindring af intraventrikulær blødning hos for tidligt fødte børn Download PDF

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Publication number
DK174978B1
DK174978B1 DK198900838A DK83889A DK174978B1 DK 174978 B1 DK174978 B1 DK 174978B1 DK 198900838 A DK198900838 A DK 198900838A DK 83889 A DK83889 A DK 83889A DK 174978 B1 DK174978 B1 DK 174978B1
Authority
DK
Denmark
Prior art keywords
factor xiii
coagulation factor
drug
precipitate
preparation
Prior art date
Application number
DK198900838A
Other languages
Danish (da)
English (en)
Other versions
DK83889D0 (da
DK83889A (da
Inventor
Minoru Uchida
Satoshi Tanaka
Akira Shirahata
Kenichiro Tsumura
Original Assignee
Hoechst Japan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Japan filed Critical Hoechst Japan
Publication of DK83889D0 publication Critical patent/DK83889D0/da
Publication of DK83889A publication Critical patent/DK83889A/da
Application granted granted Critical
Publication of DK174978B1 publication Critical patent/DK174978B1/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/16Blood plasma; Blood serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45Transferases (2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Virology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK198900838A 1988-02-24 1989-02-23 Anvendelse af human koagulationsfaktor XIII til fremstilling af et lægemiddel til hindring af intraventrikulær blødning hos for tidligt fødte børn DK174978B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP3964688 1988-02-24
JP63039646A JPH01216939A (ja) 1988-02-24 1988-02-24 末熟児頭蓋内出血阻止剤

Publications (3)

Publication Number Publication Date
DK83889D0 DK83889D0 (da) 1989-02-23
DK83889A DK83889A (da) 1989-08-25
DK174978B1 true DK174978B1 (da) 2004-04-05

Family

ID=12558846

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198900838A DK174978B1 (da) 1988-02-24 1989-02-23 Anvendelse af human koagulationsfaktor XIII til fremstilling af et lægemiddel til hindring af intraventrikulær blødning hos for tidligt fødte børn

Country Status (12)

Country Link
US (1) US5114916A (es)
EP (1) EP0330049B1 (es)
JP (1) JPH01216939A (es)
KR (1) KR0137476B1 (es)
AT (1) ATE94070T1 (es)
AU (1) AU613154B2 (es)
CA (1) CA1332352C (es)
DE (1) DE68908913T2 (es)
DK (1) DK174978B1 (es)
ES (1) ES2059588T3 (es)
IE (1) IE63656B1 (es)
PT (1) PT89802B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5612456A (en) * 1988-11-14 1997-03-18 Zymogenetics, Inc. Factor XIII compositions
DE69227042T3 (de) * 1991-12-31 2006-07-27 Zymogenetics, Inc., Seattle Verfahren und zusammensetzungen zur verminderung von blutverlust
US5525335A (en) * 1992-04-21 1996-06-11 Ajinomoto Co., Inc. Wound healing agent
WO1994011022A1 (en) * 1992-11-12 1994-05-26 Zymogenetics, Inc. Use of topically applied factor xiii for inhibiting hemorrhage
JPH07328108A (ja) * 1994-06-10 1995-12-19 Ajinomoto Co Inc 生体組織接着剤及び血液凝固剤
DK1100542T3 (da) 1998-08-06 2005-10-17 Mountain View Pharmaceuticals PEG-uratoxidasekonjugater og anvendelsen heraf
JP2008510476A (ja) * 2004-08-27 2008-04-10 ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト 生物学的材料からのxiii因子ポリペプチドの精製
EP1817339B1 (en) * 2004-11-23 2012-01-11 ZymoGenetics, Inc. Purification of recombinant human factor xiii
TWI418564B (zh) * 2005-04-11 2013-12-11 Savient Pharmaceuticals Inc 利用陽離子界面活性劑之蛋白質純化
RU2451074C2 (ru) 2005-04-11 2012-05-20 Савиент Фармасьютикалз, Инк. Вариантные формы уратоксидазы и их применение
CN101622270B (zh) * 2006-04-12 2014-01-01 萨文特医药公司 用阳离子表面活性剂纯化蛋白质的方法
NZ597089A (en) 2009-06-25 2014-05-30 Savient Pharmaceuticals Inc Methods and kits for predicting infusion reaction risk and antibody-mediated loss of response by monitoring serum uric acid during pegylated uricase therapy
WO2020160322A1 (en) 2019-01-30 2020-08-06 Horizon Pharma Rheumatology Llc Tolerization reduces intolerance to pegloticase and prolongs the urate lowering effect (triple)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3717708A (en) * 1968-10-24 1973-02-20 Cutter Lab Blood coagulation complex
DE2063070C3 (de) * 1970-12-22 1975-07-24 Behringwerke Ag, 3550 Marburg Verfahren zur Herstellung eines Arzneimittels mit fibrinstabilisierender Wirkung
DE3622642A1 (de) * 1986-07-05 1988-01-14 Behringwerke Ag Einkomponenten-gewebekleber sowie verfahren zu seiner herstellung
EP0268772B1 (en) * 1986-09-19 1995-04-26 ZymoGenetics, Inc. Expression of biologically active factor XIII

Also Published As

Publication number Publication date
ES2059588T3 (es) 1994-11-16
US5114916A (en) 1992-05-19
EP0330049B1 (en) 1993-09-08
DE68908913D1 (de) 1993-10-14
CA1332352C (en) 1994-10-11
JPH01216939A (ja) 1989-08-30
IE63656B1 (en) 1995-05-31
PT89802B (pt) 1994-04-29
AU613154B2 (en) 1991-07-25
DE68908913T2 (de) 1994-01-27
EP0330049A2 (en) 1989-08-30
PT89802A (pt) 1989-10-04
KR0137476B1 (ko) 1998-06-01
EP0330049A3 (en) 1991-01-30
DK83889D0 (da) 1989-02-23
ATE94070T1 (de) 1993-09-15
KR890012659A (ko) 1989-09-18
AU3024389A (en) 1989-08-24
DK83889A (da) 1989-08-25
IE890580L (en) 1989-08-24
JPH0378850B2 (es) 1991-12-17

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