DK173873B1 - Cyclosporiner og farmaceutiske præparater indeholdende dem - Google Patents

Cyclosporiner og farmaceutiske præparater indeholdende dem Download PDF

Info

Publication number: DK173873B1
Authority: DK; Denmark
Prior art keywords: mebmt; ciclosporin; acetyl; desmethyl; cis
Prior art date: 1987-06-17

Application number

DK198803265A

Other languages

Danish (da)

English (en)

Other versions

DK326588A (da

DK326588D0 (da

Inventor

Roland Wenger

Pietro Bollinger

Johann Jakob Boelsterli

Trevor Glyn Payne

Rene P Traber

Jean Francois Borel

Manfred Krieger

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-06-17

Filing date

1988-06-15

Publication date

2002-01-21

1987-06-17 Priority claimed from GB878714090A external-priority patent/GB8714090D0/en

1987-06-17 Priority claimed from GB878714119A external-priority patent/GB8714119D0/en

1987-06-17 Priority claimed from GB878714098A external-priority patent/GB8714098D0/en

1987-06-17 Priority claimed from GB878714093A external-priority patent/GB8714093D0/en

1987-06-17 Priority claimed from GB878714125A external-priority patent/GB8714125D0/en

1987-06-17 Priority claimed from GB878714118A external-priority patent/GB8714118D0/en

1987-06-17 Priority claimed from GB878714100A external-priority patent/GB8714100D0/en

1987-06-17 Priority claimed from GB878714115A external-priority patent/GB8714115D0/en

1988-06-15 Publication of DK326588D0 publication Critical patent/DK326588D0/da

1988-06-15 Application filed by Novartis Ag filed Critical Novartis Ag

1988-12-18 Publication of DK326588A publication Critical patent/DK326588A/da

2002-01-21 Application granted granted Critical

2002-01-21 Publication of DK173873B1 publication Critical patent/DK173873B1/da

Links

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OGWKCGZFUXNPDA-XQKSVPLYSA-N vincristine Chemical compound C([N@]1C[C@@H](C[C@]2(C(=O)OC)C=3C(=CC4=C([C@]56[C@H]([C@@]([C@H](OC(C)=O)[C@]7(CC)C=CCN([C@H]67)CC5)(O)C(=O)OC)N4C=O)C=3)OC)C[C@@](C1)(O)CC)CC1=C2NC2=CC=CC=C12 OGWKCGZFUXNPDA-XQKSVPLYSA-N 0.000 description 1
229960004528 vincristine Drugs 0.000 description 1
229930003231 vitamin Natural products 0.000 description 1
239000011782 vitamin Substances 0.000 description 1
235000013343 vitamin Nutrition 0.000 description 1
229940088594 vitamin Drugs 0.000 description 1
238000005303 weighing Methods 0.000 description 1
239000002023 wood Substances 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
- C07K7/645—Cyclosporins; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Biochemistry (AREA)
Oncology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Immunology (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Communicable Diseases (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Hematology (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Tropical Medicine & Parasitology (AREA)
Transplantation (AREA)
Virology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DK198803265A 1987-06-17 1988-06-15 Cyclosporiner og farmaceutiske præparater indeholdende dem DK173873B1 (da)

Applications Claiming Priority (16)

Application Number	Priority Date	Filing Date	Title
GB8714119		1987-06-17
GB8714125		1987-06-17
GB878714119A GB8714119D0 (en)	1987-06-17	1987-06-17	Organic compounds
GB878714098A GB8714098D0 (en)	1987-06-17	1987-06-17	Organic compounds
GB878714093A GB8714093D0 (en)	1987-06-17	1987-06-17	Organic compounds
GB8714090		1987-06-17
GB878714125A GB8714125D0 (en)	1987-06-17	1987-06-17	Organic compounds
GB8714093		1987-06-17
GB8714118		1987-06-17
GB8714100		1987-06-17
GB878714090A GB8714090D0 (en)	1987-06-17	1987-06-17	Organic compounds
GB878714118A GB8714118D0 (en)	1987-06-17	1987-06-17	Organic compounds
GB878714100A GB8714100D0 (en)	1987-06-17	1987-06-17	Organic compounds
GB878714115A GB8714115D0 (en)	1987-06-17	1987-06-17	Organic compounds
GB8714115		1987-06-17
GB8714098		1987-06-17

Publications (3)

Publication Number	Publication Date
DK326588D0 DK326588D0 (da)	1988-06-15
DK326588A DK326588A (da)	1988-12-18
DK173873B1 true DK173873B1 (da)	2002-01-21

Family

ID=27571252

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK198803265A DK173873B1 (da)	1987-06-17	1988-06-15	Cyclosporiner og farmaceutiske præparater indeholdende dem

Country Status (21)

Country	Link
US (1)	US5525590A (hu)
EP (1)	EP0296122B1 (hu)
JP (2)	JPH0832724B2 (hu)
KR (1)	KR970010927B1 (hu)
AT (1)	ATE95193T1 (hu)
AU (1)	AU614086B2 (hu)
CA (1)	CA1338728C (hu)
CY (1)	CY1939A (hu)
CZ (1)	CZ411791A3 (hu)
DE (1)	DE3884470T2 (hu)
DK (1)	DK173873B1 (hu)
ES (1)	ES2059558T3 (hu)
HK (1)	HK152796A (hu)
HU (1)	HU211678A9 (hu)
IE (1)	IE62482B1 (hu)
IL (1)	IL86751A (hu)
MY (1)	MY103582A (hu)
NZ (1)	NZ225041A (hu)
PT (1)	PT87745B (hu)
SA (1)	SA97170746A (hu)
SK (1)	SK411791A3 (hu)

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1988
- 1988-06-14 DE DE88810403T patent/DE3884470T2/de not_active Expired - Lifetime
- 1988-06-14 ES ES88810403T patent/ES2059558T3/es not_active Expired - Lifetime
- 1988-06-14 EP EP88810403A patent/EP0296122B1/en not_active Expired - Lifetime
- 1988-06-14 AT AT88810403T patent/ATE95193T1/de not_active IP Right Cessation
- 1988-06-15 NZ NZ225041A patent/NZ225041A/en unknown
- 1988-06-15 CA CA000569523A patent/CA1338728C/en not_active Expired - Fee Related
- 1988-06-15 IE IE180788A patent/IE62482B1/en not_active IP Right Cessation
- 1988-06-15 IL IL8675188A patent/IL86751A/en not_active IP Right Cessation
- 1988-06-15 AU AU17679/88A patent/AU614086B2/en not_active Expired
- 1988-06-15 MY MYPI88000662A patent/MY103582A/en unknown
- 1988-06-15 DK DK198803265A patent/DK173873B1/da not_active IP Right Cessation
- 1988-06-16 PT PT87745A patent/PT87745B/pt not_active IP Right Cessation
- 1988-06-16 JP JP63149227A patent/JPH0832724B2/ja not_active Expired - Lifetime
- 1988-06-16 KR KR1019880007330A patent/KR970010927B1/ko not_active Expired - Fee Related
1991
- 1991-12-27 CZ CS914117A patent/CZ411791A3/cs unknown
- 1991-12-27 SK SK4117-91A patent/SK411791A3/sk unknown
1994
- 1994-11-10 US US08/337,346 patent/US5525590A/en not_active Expired - Lifetime
1995
- 1995-06-22 HU HU95P/P00332P patent/HU211678A9/hu unknown
- 1995-08-16 JP JP7208783A patent/JP2772372B2/ja not_active Expired - Lifetime
1996
- 1996-08-08 HK HK152796A patent/HK152796A/xx not_active IP Right Cessation
1997
- 1997-03-25 SA SA97170746A patent/SA97170746A/ar unknown
- 1997-05-16 CY CY193997A patent/CY1939A/xx unknown

Also Published As

Publication number	Publication date
HU211678A9 (en)	1995-12-28
JPH0832724B2 (ja)	1996-03-29
DE3884470D1 (de)	1993-11-04
ATE95193T1 (de)	1993-10-15
AU1767988A (en)	1988-12-22
KR970010927B1 (ko)	1997-07-02
CZ411791A3 (en)	1993-02-17
PT87745A (pt)	1988-07-01
EP0296122B1 (en)	1993-09-29
CA1338728C (en)	1996-11-19
JPS6445396A (en)	1989-02-17
JP2772372B2 (ja)	1998-07-02
JPH0848696A (ja)	1996-02-20
ES2059558T3 (es)	1994-11-16
DE3884470T2 (de)	1994-03-10
EP0296122A2 (en)	1988-12-21
MY103582A (en)	1993-08-28
DK326588A (da)	1988-12-18
NZ225041A (en)	1991-03-26
IL86751A0 (en)	1988-11-30
IE881807L (en)	1988-12-17
KR890000519A (ko)	1989-03-15
US5525590A (en)	1996-06-11
SK411791A3 (en)	1995-07-11
PT87745B (pt)	1992-10-30
IE62482B1 (en)	1995-02-08
IL86751A (en)	1994-02-27
AU614086B2 (en)	1991-08-22
EP0296122A3 (en)	1990-06-20
CY1939A (en)	1997-05-16
DK326588D0 (da)	1988-06-15
HK152796A (en)	1996-08-16
SA97170746A (ar)	2005-12-03

Publication	Publication Date	Title
DK173873B1 (da)	2002-01-21	Cyclosporiner og farmaceutiske præparater indeholdende dem
US4639434A (en)	1987-01-27	Novel cyclosporins
US4764503A (en)	1988-08-16	Novel cyclosporins
US4384996A (en)	1983-05-24	Novel cyclosporins
JP3425763B2 (ja)	2003-07-14	有機化合物
RU2482130C2 (ru)	2013-05-20	Циклическое соединение и его соль
SK12262002A3 (sk)	2003-02-04	Memnopeptidy, spôsob ich prípravy, kompozície, ktoré ich obsahujú a ich použitie ako liečiva
US7704957B2 (en)	2010-04-27	Composition for inhibiting HIV activity extracted from Paecilomyces sp. (Tochu-kaso) J300
KR0173972B1 (ko)	1999-02-01	인체 후천성 면역부전증후군 바이러스 감염 저해제
EP0866801A1 (en)	1998-09-30	Cyclopeptolides
JP4452787B2 (ja)	2010-04-21	新規発酵生産物
DD241908A5 (de)	1987-01-07	Verfahren zur herstellung eines cyclosporins
JPH1129561A (ja)	1999-02-02	新規化合物ａｍ６１０５及びその製法
JP2000212196A (ja)	2000-08-02	生理活性物質ｄｍ９８０９およびこれを有効成分とする医薬
JPH09309859A (ja)	1997-12-02	新規化合物ａｍ６８９８及びその製法
JPH10139771A (ja)	1998-05-26	新規化合物ａｍ６９２７及びその製法
JPH11116577A (ja)	1999-04-27	新規化合物ａｍ６８９８ｅ及びその製法
RO110144B1 (ro)	1995-10-30	Noi ciclosporine, procedeu de sinteză a acestora și metodă de tratament și prevenire a SIDA

Legal Events

Date	Code	Title	Description
2002-01-21	B1	Patent granted (law 1993)
2008-06-30	PUP	Patent expired