DK173278B1 - Humant IL-3-protein, farmaceutisk præparat indeholdende proteinet, vektor, som koder for proteinet, celle transformeret med - Google Patents

Humant IL-3-protein, farmaceutisk præparat indeholdende proteinet, vektor, som koder for proteinet, celle transformeret med Download PDF

Info

Publication number: DK173278B1
Authority: DK; Denmark
Prior art keywords: leu; asn; pro; ala; thr
Prior art date: 1986-07-14

Application number

DK198801354A

Other languages

Danish (da)

English (en)

Other versions

DK135488A (da

DK135488D0 (da

Inventor

Steven C Clark

Agnes B Ciarletta

Yu-Chung Yang

Original Assignee

Genetics Inst

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-07-14

Filing date

1988-03-11

Publication date

2000-06-05

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27487045&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK173278(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1986-10-07 Priority claimed from US06/916,335 external-priority patent/US4877729A/en

1987-03-04 Priority claimed from US07/021,865 external-priority patent/US4959455A/en

1988-03-11 Application filed by Genetics Inst filed Critical Genetics Inst

1988-03-11 Publication of DK135488A publication Critical patent/DK135488A/da

1988-03-11 Publication of DK135488D0 publication Critical patent/DK135488D0/da

2000-06-05 Application granted granted Critical

2000-06-05 Publication of DK173278B1 publication Critical patent/DK173278B1/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5403—IL-3
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
Gastroenterology & Hepatology (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Engineering & Computer Science (AREA)
Toxicology (AREA)
Zoology (AREA)
Diabetes (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Hematology (AREA)
Immunology (AREA)
Virology (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
External Artificial Organs (AREA)
Glass Compositions (AREA)
Crystals, And After-Treatments Of Crystals (AREA)
Gas Separation By Absorption (AREA)
Treating Waste Gases (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK198801354A 1986-07-14 1988-03-11 Humant IL-3-protein, farmaceutisk præparat indeholdende proteinet, vektor, som koder for proteinet, celle transformeret med DK173278B1 (da)

Applications Claiming Priority (10)

Application Number	Priority Date	Filing Date	Title
US88506086A	1986-07-14	1986-07-14
US88506086		1986-07-14
US89376486A	1986-08-06	1986-08-06
US89376486		1986-08-06
US06/916,335 US4877729A (en)	1986-07-14	1986-10-07	Recombinant DNA encoding novel family of primate hematopoietic growth factors
US91633586		1986-10-07
US07/021,865 US4959455A (en)	1986-07-14	1987-03-04	Primate hematopoietic growth factors IL-3 and pharmaceutical compositions
US2186587		1987-03-04
US8701702		1987-07-13
PCT/US1987/001702 WO1988000598A1 (en)	1986-07-14	1987-07-13	A novel family of primate hematopoietic growth factors

Publications (3)

Publication Number	Publication Date
DK135488A DK135488A (da)	1988-03-11
DK135488D0 DK135488D0 (da)	1988-03-11
DK173278B1 true DK173278B1 (da)	2000-06-05

Family

ID=27487045

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK198801354A DK173278B1 (da)	1986-07-14	1988-03-11	Humant IL-3-protein, farmaceutisk præparat indeholdende proteinet, vektor, som koder for proteinet, celle transformeret med

Country Status (23)

Country	Link
US (1)	US5639453A (fi)
EP (2)	EP0314705B2 (fi)
JP (2)	JP2642942B2 (fi)
KR (1)	KR970003518B1 (fi)
CN (1)	CN1023901C (fi)
AT (2)	ATE133182T1 (fi)
AU (1)	AU606881B2 (fi)
CA (1)	CA1341489C (fi)
CZ (1)	CZ531387A3 (fi)
DE (2)	DE3751677T3 (fi)
DK (1)	DK173278B1 (fi)
ES (1)	ES2007642A6 (fi)
FI (1)	FI104903B (fi)
GR (1)	GR871029B (fi)
HU (1)	HU212518B (fi)
MY (1)	MY101578A (fi)
NO (1)	NO175825C (fi)
NZ (1)	NZ221046A (fi)
OA (1)	OA09226A (fi)
PH (1)	PH26757A (fi)
PL (1)	PL159183B1 (fi)
PT (1)	PT85323B (fi)
WO (1)	WO1988000598A1 (fi)

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ES2113338T3 (es) *	1986-12-16	1998-05-01	Gist Brocades Nv	Clonado molecular y expresion de il-3 humano.
US6238889B1 (en)	1986-12-16	2001-05-29	Dsm N.V.	Molecular cloning and expression of the Pro8 isoform of human IL-3
EP0790307A1 (en) *	1986-12-16	1997-08-20	Gist-Brocades B.V.	Molecular cloning and expression of human IL-3
OA09736A (en) *	1987-02-18	1993-11-30	Schering Biotech Corp	"Human interleukin-3 and muteins thereof".
US5304637A (en) *	1987-07-13	1994-04-19	Gist-Brocades N.V.	Expression and purification of human interleukin-3 and muteins thereof
GB2210883B (en) *	1987-10-08	1992-01-02	British Bio Technology	Synthetic interleukin-3 gene
CA1338678C (en) *	1987-12-02	1996-10-22	Tyndale Plains-Hunter Ltd.	Hydrophilic polyurethanes of improved strength
US6384194B1 (en)	1987-12-16	2002-05-07	Dsm N.V.	Expression and purification of human interleukin-3 and muteins thereof
NZ232913A (en) *	1989-03-15	1992-08-26	Gist Brocades Nv	Il-3 produced recombinantly and purified to homogeneity; vectors and pharmaceutical preparations
US5516512A (en) *	1989-08-14	1996-05-14	Gist-Brocades, N.V.	N- and C-terminal truncation and deletion mutants of human interleukin-3
EP0413383B1 (en)	1989-08-14	1997-06-18	Gist-Brocades N.V.	Mutants of human interleukin-3
US6403076B1 (en)	1992-11-24	2002-06-11	S. Christopher Bauer	Compositions for increasing hematopoiesis with interleukin-3 mutants
DE69332908T2 (de) *	1992-11-24	2003-12-24	G.D. Searle & Co., Chicago	Interleukin-3 (il-3)-polypeptide mith mehreren mutationen
US5738849A (en) *	1992-11-24	1998-04-14	G. D. Searle & Co.	Interleukin-3 (IL-3) variant fusion proteins, their recombinant production, and therapeutic compositions comprising them
US6153183A (en)	1992-11-24	2000-11-28	G. D. Searle & Company	Co-administration of interleukin-3 mutant polypeptides with CSF's or cytokines for multi-lineage hematopoietic cell production
US6361976B1 (en)	1992-11-24	2002-03-26	S. Christopher Bauer	Co-administration of interleukin-3 mutant polypeptides with CSF'S for multi-lineage hematopoietic cell production
US5772992A (en) *	1992-11-24	1998-06-30	G.D. Searle & Co.	Compositions for co-administration of interleukin-3 mutants and other cytokines and hematopoietic factors
JP3149185B2 (ja) *	1993-01-15	2001-03-26	ジェネティックス・インスティテュート・インコーポレイテッド	エンテロキナーゼのクローニングおよび使用方法
US6746859B1 (en)	1993-01-15	2004-06-08	Genetics Institute, Llc	Cloning of enterokinase and method of use
US5501962A (en) *	1993-06-21	1996-03-26	G. D. Searle & Co.	Interleuken-3 (IL-3) human/murine hybrid polypeptides and recombinant production of the same
US6017523A (en) *	1995-06-06	2000-01-25	G.D. Searle & Co.	Therapeutic methods employing mutant human interleukin-3 (IL-3) polypeptides
WO2000038705A1 (en) *	1998-12-23	2000-07-06	Korkut Edib M D Ph D	Protection of hematopoietic cells by the induction of post-mitotic quiescence
WO2002044410A1 (en) *	2000-11-28	2002-06-06	Genaissance Pharmaceuticals, Inc.	Drug target isogenes: polymorphisms in the interleukin 3 (colony-stimulating factor, multiple) gene
CA2531878A1 (en) *	2003-05-09	2005-03-24	Curagen Corporation	Therapeutic use of g53135-05(fgf-20) in radiation protection
US7597884B2 (en)	2004-08-09	2009-10-06	Alios Biopharma, Inc.	Hyperglycosylated polypeptide variants and methods of use
JP6087506B2 (ja) *	2012-01-31	2017-03-01	キヤノン株式会社	描画方法及び物品の製造方法

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US21865A (en) *		1858-10-19		moeison
US885060A (en) *	1907-04-13	1908-04-21	Alfred Leatherman	Ratchet-cylinder pulley.
US893764A (en) *	1907-05-20	1908-07-21	Cable Co	Supporting means for swinging parts of musical instruments.
US916335A (en) *	1908-05-08	1909-03-23	Klamath River Gold Mining Co	Aerial tramway.
US4419446A (en)	1980-12-31	1983-12-06	The United States Of America As Represented By The Department Of Health And Human Services	Recombinant DNA process utilizing a papilloma virus DNA as a vector
IN159327B (fi) *	1982-09-02	1987-05-02	Smidth & Co As F L
JPS5962335A (ja) *	1982-09-30	1984-04-09	Kawasaki Steel Corp	グレ−トキルン法によるｅｐダストの予備焼成法
US4518584A (en)	1983-04-15	1985-05-21	Cetus Corporation	Human recombinant interleukin-2 muteins
US4588684A (en)	1983-04-26	1986-05-13	Chiron Corporation	a-Factor and its processing signals
US4695542A (en) *	1983-10-04	1987-09-22	Dnax Research Institute Of Molecular And Cellular Biology, Inc.	cDNA clones coding for polypeptides exhibiting multi-lineage cellular growth factor activity
NZ210501A (en)	1983-12-13	1991-08-27	Kirin Amgen Inc	Erythropoietin produced by procaryotic or eucaryotic expression of an exogenous dna sequence
EP0167548B1 (en) *	1983-12-23	1993-02-10	The Australian National University	Cloning of cdna and expression of murine-interleukin-3
ZA848495B (en)	1984-01-31	1985-09-25	Idaho Res Found	Production of polypeptides in insect cells
US4658018A (en) *	1984-03-13	1987-04-14	Immunex Corporation	Process for producing homogeneous colony stimulating factor
JPS60207594A (ja) *	1984-03-30	1985-10-19	Ajinomoto Co Inc	ヒトインタ−ロイキン３の製造方法
JPS60207595A (ja) *	1984-03-30	1985-10-19	Ajinomoto Co Inc	ヒトインタ−ロイキン３の製造法
EP0188479B1 (en)	1984-07-06	1991-09-11	Sandoz Ag	Lymphokine production and purification
DE3586386T2 (de)	1984-10-05	1993-01-14	Genentech Inc	Dna, zellkulturen und verfahren zur sekretion von heterologen proteinen und periplasmische proteinrueckgewinnung.
EP0253870B1 (en)	1986-01-03	1993-03-31	Genetics Institute, Inc.	Method for producing factor viii:c-type proteins
US4877729A (en) *	1986-07-14	1989-10-31	Genetics Institute, Inc.	Recombinant DNA encoding novel family of primate hematopoietic growth factors
ES2113338T3 (es) *	1986-12-16	1998-05-01	Gist Brocades Nv	Clonado molecular y expresion de il-3 humano.
EP0790307A1 (en) *	1986-12-16	1997-08-20	Gist-Brocades B.V.	Molecular cloning and expression of human IL-3
WO1988005469A1 (en) *	1987-01-20	1988-07-28	Immunex Corporation	Human interleukin-3 proteins
OA09736A (en) *	1987-02-18	1993-11-30	Schering Biotech Corp	"Human interleukin-3 and muteins thereof".

1987
- 1987-06-30 GR GR871029A patent/GR871029B/el unknown
- 1987-07-03 CA CA000541215A patent/CA1341489C/en not_active Expired - Fee Related
- 1987-07-09 PH PH35515A patent/PH26757A/en unknown
- 1987-07-10 ES ES8702042A patent/ES2007642A6/es not_active Expired
- 1987-07-13 NZ NZ221046A patent/NZ221046A/xx unknown
- 1987-07-13 CZ CS875313A patent/CZ531387A3/cs unknown
- 1987-07-13 DE DE3751677T patent/DE3751677T3/de not_active Expired - Lifetime
- 1987-07-13 JP JP62504556A patent/JP2642942B2/ja not_active Expired - Lifetime
- 1987-07-13 KR KR1019880700288A patent/KR970003518B1/ko not_active IP Right Cessation
- 1987-07-13 EP EP87905074A patent/EP0314705B2/en not_active Expired - Lifetime
- 1987-07-13 PL PL1987266802A patent/PL159183B1/pl unknown
- 1987-07-13 AT AT87905074T patent/ATE133182T1/de not_active IP Right Cessation
- 1987-07-13 HU HU874240A patent/HU212518B/hu unknown
- 1987-07-13 WO PCT/US1987/001702 patent/WO1988000598A1/en active IP Right Grant
- 1987-07-13 MY MYPI87000992A patent/MY101578A/en unknown
- 1987-07-13 EP EP95108668A patent/EP0691403B1/en not_active Expired - Lifetime
- 1987-07-13 DE DE3752394T patent/DE3752394D1/de not_active Expired - Lifetime
- 1987-07-13 AU AU77593/87A patent/AU606881B2/en not_active Expired
- 1987-07-13 AT AT95108668T patent/ATE433487T1/de not_active IP Right Cessation
- 1987-07-14 PT PT85323A patent/PT85323B/pt unknown
- 1987-07-14 CN CN87104815A patent/CN1023901C/zh not_active Expired - Lifetime
1988
- 1988-03-10 NO NO881073A patent/NO175825C/no not_active IP Right Cessation
- 1988-03-11 DK DK198801354A patent/DK173278B1/da not_active IP Right Cessation
1989
- 1989-01-12 FI FI890153A patent/FI104903B/fi not_active IP Right Cessation
- 1989-01-13 OA OA59507A patent/OA09226A/xx unknown
1995
- 1995-01-10 US US08/370,277 patent/US5639453A/en not_active Expired - Lifetime
- 1995-01-11 JP JP7002454A patent/JP2655591B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
DE3752394D1 (de)	2009-07-23
EP0314705B1 (en)	1996-01-17
NZ221046A (en)	1991-02-26
EP0691403A1 (en)	1996-01-10
MY101578A (en)	1991-12-17
WO1988000598A1 (en)	1988-01-28
PH26757A (en)	1992-09-28
AU606881B2 (en)	1991-02-21
PL159183B1 (pl)	1992-11-30
KR880701737A (ko)	1988-11-04
NO881073D0 (no)	1988-03-10
AU7759387A (en)	1988-02-10
NO881073L (no)	1988-03-10
PL266802A1 (en)	1988-06-09
DE3751677D1 (de)	1996-02-29
DK135488A (da)	1988-03-11
CA1341489C (en)	2005-08-30
JPH07203967A (ja)	1995-08-08
ATE133182T1 (de)	1996-02-15
PT85323A (en)	1987-08-01
DE3751677T3 (de)	2007-03-15
PT85323B (pt)	1990-04-30
CN1023901C (zh)	1994-03-02
EP0314705A4 (en)	1990-02-26
JPH01503298A (ja)	1989-11-09
ES2007642A6 (es)	1989-07-01
DK135488D0 (da)	1988-03-11
JP2655591B2 (ja)	1997-09-24
US5639453A (en)	1997-06-17
OA09226A (en)	1992-06-30
NO175825B (no)	1994-09-05
NO175825C (no)	1994-12-14
EP0691403B1 (en)	2009-06-10
CZ531387A3 (en)	1997-10-15
EP0314705B2 (en)	2006-08-16
ATE433487T1 (de)	2009-06-15
DE3751677T2 (de)	1996-08-08
FI104903B (fi)	2000-04-28
JP2642942B2 (ja)	1997-08-20
KR970003518B1 (ko)	1997-03-18
EP0314705A1 (en)	1989-05-10
CN87104815A (zh)	1988-07-20
HU212518B (en)	1996-07-29
FI890153A0 (fi)	1989-01-12
GR871029B (en)	1987-11-02
FI890153A (fi)	1989-01-12

Publication	Publication Date	Title
DK173278B1 (da)	2000-06-05	Humant IL-3-protein, farmaceutisk præparat indeholdende proteinet, vektor, som koder for proteinet, celle transformeret med
US4959455A (en)	1990-09-25	Primate hematopoietic growth factors IL-3 and pharmaceutical compositions
US4877729A (en)	1989-10-31	Recombinant DNA encoding novel family of primate hematopoietic growth factors
EP0473724B1 (en)	1997-01-08	A human cytokine, interleukin-9
DE69527041T2 (de)	2002-12-19	Gleichzeitige verarbeitung von interleukin-3 mutanten und kolonie stimulierungsfactor
DK173279B1 (da)	2000-06-05	Rekombinant IL-6, fremgangsmåde til dets fremstilling og vektor til brug ved denne fremstilling samt dets anvendelse
US6066317A (en)	2000-05-23	Method of using IL-11 for treating deficiencies in hematopoietic progenitor or stem cells
US7361738B2 (en)	2008-04-22	Megakaryocyte stimulating factors
EP0549711A1 (en)	1993-07-07	Natural killer stimulatory factor
US20040044186A1 (en)	2004-03-04	Antibodies to natural killer stimulatory factor
US5414071A (en)	1995-05-09	Human cytokine IL-9
KR970004941B1 (ko)	1997-04-10	신규 영장류 조혈 성장 인자족(family) 발현용 벡터 및 형질전환체
IE871727L (en)	1988-01-14	Novel family of primate il3-like hematopoietic growth¹factors.

Legal Events

Date	Code	Title	Description
2007-08-06	PUP	Patent expired