DK1720909T3 - Anti-Abeta antistof - Google Patents

Anti-Abeta antistof

Info

Publication number: DK1720909T3
Authority: DK; Denmark
Prior art keywords: abeta; abeta antibody; free; low levels; abeta peptide
Prior art date: 2004-02-23

Application number

DK05723280.3T

Other languages

English (en)

Inventor

Ronald Bradley Demattos

Uma Kuchibhotla

Hsiu-Chiung Yang

Don B Mcclure

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-02-23

Filing date

2005-02-17

Publication date

2012-01-30

2005-02-17 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

2012-01-30 Application granted granted Critical

2012-01-30 Publication of DK1720909T3 publication Critical patent/DK1720909T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Neurosurgery (AREA)
Immunology (AREA)
Neurology (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
Biophysics (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Steroid Compounds (AREA)

DK05723280.3T 2004-02-23 2005-02-17 Anti-Abeta antistof DK1720909T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US54676404P	2004-02-23	2004-02-23
PCT/US2005/005198 WO2005082939A2 (en)	2004-02-23	2005-02-17	Anti-abeta antibody

Publications (1)

Publication Number	Publication Date
DK1720909T3 true DK1720909T3 (da)	2012-01-30

Family

ID=34910810

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK05723280.3T DK1720909T3 (da)	2004-02-23	2005-02-17	Anti-Abeta antistof

Country Status (20)

Country	Link
US (1)	US20070190046A1 (da)
EP (1)	EP1720909B1 (da)
JP (1)	JP4851348B2 (da)
KR (2)	KR100889430B1 (da)
CN (1)	CN1922209B (da)
AT (1)	ATE534667T1 (da)
AU (1)	AU2005217596B2 (da)
BR (1)	BRPI0507856A (da)
CA (1)	CA2556436C (da)
CY (1)	CY1112162T1 (da)
DK (1)	DK1720909T3 (da)
EA (1)	EA009872B1 (da)
ES (1)	ES2375627T3 (da)
IL (1)	IL177611A (da)
NO (1)	NO20064239L (da)
PL (1)	PL1720909T3 (da)
PT (1)	PT1720909E (da)
SI (1)	SI1720909T1 (da)
UA (1)	UA93181C2 (da)
WO (1)	WO2005082939A2 (da)

Families Citing this family (32)

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DE10303974A1 (de)	2003-01-31	2004-08-05	Abbott Gmbh & Co. Kg	Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung
ES2453941T5 (es)	2005-11-30	2017-05-31	Abbvie Inc.	Anticuerpos monoclonales contra la proteína beta amiloide y usos de los mismos
BRPI0619249A2 (pt)	2005-11-30	2011-09-20	Abbott Lab	anticorpos anti-globulÈmeros-aß, frações que se ligam a antìgeno destes, hibridomas correspondentes, ácidos nucléicos, vetores, células hospedeiras, métodos de produzir os ditos anticorpos, composições compreendendo os ditos anticorpos, usos dos ditos anticorpos e métodos de usar os ditos anticorpos
KR101591206B1 (ko)	2005-12-12	2016-02-04	에이씨 이뮨 에스.에이.	치료적 특성을 갖는 베타 1-42 특이적인 단일클론성 항체
EP2046833B9 (en)	2006-07-14	2014-02-19	AC Immune S.A.	Humanized antibody against amyloid beta
US8455626B2 (en) *	2006-11-30	2013-06-04	Abbott Laboratories	Aβ conformer selective anti-aβ globulomer monoclonal antibodies
IL199534A (en)	2007-01-05	2013-01-31	Univ Zuerich	An isolated human antibody capable of detecting a neoepitope in a disease-related protein, a polynucleotide encoding an antibody, a vector containing the polynucleotide, a host cell containing the polynucleotide or vector, a preparation containing the antibody and related methods and uses.
ES2641897T3 (es) *	2007-01-05	2017-11-14	University Of Zurich	Procedimiento para proporcionar moléculas de unión y diana específicas de una enfermedad
EP2104682B1 (en)	2007-01-11	2016-09-21	Michael Bacher	Diagnosis and treatment of alzheimer's and other neurodementing diseases
WO2008104386A2 (en)	2007-02-27	2008-09-04	Abbott Gmbh & Co. Kg	Method for the treatment of amyloidoses
US8613923B2 (en) *	2007-06-12	2013-12-24	Ac Immune S.A.	Monoclonal antibody
US8048420B2 (en) *	2007-06-12	2011-11-01	Ac Immune S.A.	Monoclonal antibody
SG178809A1 (en) *	2007-10-05	2012-03-29	Genentech Inc	Use of anti-amyloid beta antibody in ocular diseases
US9403902B2 (en)	2007-10-05	2016-08-02	Ac Immune S.A.	Methods of treating ocular disease associated with amyloid-beta-related pathology using an anti-amyloid-beta antibody
EP2376120A2 (en)	2008-11-25	2011-10-19	Biogen Idec MA Inc.	Use of dr6 and p75 antagonists to promote survival of cells of the nervous system
WO2010069603A1 (en)	2008-12-19	2010-06-24	Neurimmune Therapeutics Ag	Human anti-alpha-synuclein autoantibodies
TW201121570A (en)	2009-11-12	2011-07-01	Genentech Inc	A method of promoting dendritic spine density
EP2558494B1 (en)	2010-04-15	2018-05-23	AbbVie Inc.	Amyloid-beta binding proteins
NZ606357A (en)	2010-07-30	2015-05-29	Genentech Inc	Safe and functional humanized anti beta-amyloid antibody
PL3042917T3 (pl) *	2010-08-12	2018-07-31	Eli Lilly And Company	Przeciwciała przeciwko peptydowi beta amyloidu N3pGlu i ich zastosowanie
EP3533803B1 (en)	2010-08-14	2021-10-27	AbbVie Inc.	Anti-amyloid-beta antibodies
EP2723379B1 (en)	2011-06-23	2018-09-12	Biogen International Neuroscience GmbH	Anti-alpha synuclein binding molecules
EP2892506B1 (en)	2012-09-07	2021-11-03	Massachusetts Eye & Ear Infirmary	Treating hearing loss with the gamma-secretase inhibitor ly411575
CN104869987B (zh)	2012-09-07	2020-10-16	麻省眼耳医院	用于再生毛细胞和/或支持细胞的方法及组合物
EP3683232A1 (en)	2013-09-13	2020-07-22	F. Hoffmann-La Roche AG	Methods and compositions comprising purified recombinant polypeptides
MA41115A (fr)	2014-12-02	2017-10-10	Biogen Int Neuroscience Gmbh	Procédé de traitement de la maladie d'alzheimer
JP6840774B2 (ja)	2016-05-16	2021-03-10	ザジェネラルホスピタルコーポレイション	肺上皮エンジニアリングにおけるヒト気道幹細胞
EP3497105A1 (en) *	2016-08-11	2019-06-19	Eli Lilly And Company	Aminothiazines and their use as bace1 inhibitors
ES2945165T3 (es)	2017-08-22	2023-06-28	Biogen Ma Inc	Composiciones farmacéuticas que contienen anticuerpos anti-beta-amiloides
TWI843040B (zh)	2021-01-11	2024-05-21	美商美國禮來大藥廠	抗N3pGlu類澱粉β抗體及其用途
WO2022251048A1 (en)	2021-05-24	2022-12-01	Eli Lilly And Company	Anti-amyloid beta antibodies and uses thereof
IL314657A (en)	2022-02-03	2024-09-01	Lilly Co Eli	Regional tau imaging for diagnosing and treating alzheimer's disease

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SI0951466T1 (sl)	1996-12-23	2009-10-31	Elan Pharm Inc	Cikloalkili, laktami, laktoni in sorodne spojine, farmacevtske zmesi, ki jih vsebujejo, in metode inhibicije sproĹˇÄŤanja beta-amiloidnega peptida in/ali njegove sinteze z uporabo takih spojin
US6518011B1 (en) *	1999-01-13	2003-02-11	Bristol-Myers Squibb Company	Method for screening compounds to identify beta-amyloid production modulators
EP3070100B1 (en) *	2000-02-24	2021-07-07	Washington University St. Louis	Humanized antibodies that sequester amyloid beta peptide
AU2001257022B2 (en) *	2000-04-13	2005-02-03	Mayo Foundation For Medical Education And Research	Abeta 42 lowering agents
TWI255272B (en) *	2000-12-06	2006-05-21	Guriq Basi	Humanized antibodies that recognize beta amyloid peptide
ES2318006T3 (es) *	2001-04-30	2009-05-01	Eli Lilly And Company	Anticuerpos humanizados que reconocen el peptido beta-amiloide.

2005
- 2005-02-17 JP JP2006554230A patent/JP4851348B2/ja not_active Expired - Fee Related
- 2005-02-17 UA UAA200609258A patent/UA93181C2/ru unknown
- 2005-02-17 PL PL05723280T patent/PL1720909T3/pl unknown
- 2005-02-17 CA CA2556436A patent/CA2556436C/en not_active Expired - Fee Related
- 2005-02-17 EA EA200601545A patent/EA009872B1/ru not_active IP Right Cessation
- 2005-02-17 DK DK05723280.3T patent/DK1720909T3/da active
- 2005-02-17 WO PCT/US2005/005198 patent/WO2005082939A2/en active Application Filing
- 2005-02-17 AU AU2005217596A patent/AU2005217596B2/en not_active Ceased
- 2005-02-17 ES ES05723280T patent/ES2375627T3/es not_active Expired - Lifetime
- 2005-02-17 BR BRPI0507856-3A patent/BRPI0507856A/pt not_active IP Right Cessation
- 2005-02-17 PT PT05723280T patent/PT1720909E/pt unknown
- 2005-02-17 US US10/590,411 patent/US20070190046A1/en not_active Abandoned
- 2005-02-17 EP EP05723280A patent/EP1720909B1/en not_active Expired - Lifetime
- 2005-02-17 AT AT05723280T patent/ATE534667T1/de active
- 2005-02-17 CN CN2005800056858A patent/CN1922209B/zh not_active Expired - Fee Related
- 2005-02-17 KR KR1020067016812A patent/KR100889430B1/ko not_active IP Right Cessation
- 2005-02-17 KR KR1020087031635A patent/KR20090005410A/ko not_active Application Discontinuation
- 2005-02-17 SI SI200531422T patent/SI1720909T1/sl unknown
2006
- 2006-08-21 IL IL177611A patent/IL177611A/en not_active IP Right Cessation
- 2006-09-19 NO NO20064239A patent/NO20064239L/no not_active Application Discontinuation
2011
- 2011-12-21 CY CY20111101276T patent/CY1112162T1/el unknown

Also Published As

Publication number	Publication date
ES2375627T3 (es)	2012-03-02
SI1720909T1 (sl)	2012-01-31
CN1922209B (zh)	2012-09-05
KR100889430B1 (ko)	2009-03-23
UA93181C2 (ru)	2011-01-25
IL177611A (en)	2013-05-30
AU2005217596B2 (en)	2012-01-19
EA200601545A1 (ru)	2007-02-27
EA009872B1 (ru)	2008-04-28
PT1720909E (pt)	2011-12-23
NO20064239L (no)	2006-11-20
KR20060126785A (ko)	2006-12-08
JP2008500279A (ja)	2008-01-10
JP4851348B2 (ja)	2012-01-11
CN1922209A (zh)	2007-02-28
IL177611A0 (en)	2006-12-10
WO2005082939A3 (en)	2005-10-27
ATE534667T1 (de)	2011-12-15
PL1720909T3 (pl)	2012-04-30
AU2005217596A1 (en)	2005-09-09
EP1720909B1 (en)	2011-11-23
CY1112162T1 (el)	2015-12-09
CA2556436A1 (en)	2005-09-09
CA2556436C (en)	2014-04-01
KR20090005410A (ko)	2009-01-13
US20070190046A1 (en)	2007-08-16
WO2005082939A2 (en)	2005-09-09
EP1720909A2 (en)	2006-11-15
BRPI0507856A (pt)	2007-07-10

Publication	Publication Date	Title
DK1720909T3 (da)	2012-01-30	Anti-Abeta antistof
CY1124802T1 (el)	2022-11-25	Δεσμευτικοι παραγοντες σκληροστινης
CY1121208T1 (el)	2020-05-29	Σκευασματα αντισωματος ναταλιζουμαμπης
CO5720212A1 (es)	2007-01-31	Composicion de anticuerpo her2
DK3530673T3 (da)	2022-04-19	Humaniserede anti-beta7-antagonister og anvendelser deraf
CU20120095A7 (es)	2013-02-26	Antagonistas de pcsk9
TR201901841T4 (tr)	2019-03-21	Her antikorlarının sabit dozlaması.
CY1113199T1 (el)	2016-04-13	Σταθεροποιημενες συνθεσεις γλυκοσερεμπροσιδασης
EA201270553A1 (ru)	2012-09-28	Ингибиторы тирозинкиназы брутона
MY174493A (en)	2020-04-23	Binding agents
CL2012003245A1 (es)	2013-03-22	Proteína de unión a antígeno aislada que se une a linfopoyetina estromal tímica (tslp); composición que comprende una proteína de unión a antígeno que une tslp correspondiente a un anticuerpo humano anti-tslp.
EA200901313A1 (ru)	2010-04-30	Ингибиторы тирозинкиназы брутона
DK1877390T3 (da)	2010-05-31	Benzisoxazol-piperazin-forbindelser og fremgangsmåder til anvendelse deraf
BRPI0506679A (pt)	2007-05-15	métodos de tratar osteoartrite com antagonistas de il-6
EA200702008A1 (ru)	2008-06-30	Антитела-нейтрализаторы гранулоцитарно-макрофагального колониестимулирующего фактора человека
DK1694706T3 (da)	2012-07-16	Modificeret anti-CD52-antistof
MA33210B1 (fr)	2012-04-02	Nouveaux anticorps anti-a5b1 et leurs utilisations
NO20075985L (no)	2008-01-25	Stabil emulsjonsforbindelse
MX373170B (es)	2025-03-04	Variantes de la familia il-1.
EA200702193A1 (ru)	2008-04-28	Гликозилирование белков
EA200800601A1 (ru)	2009-08-28	Связывающие fas антитела
NO20060535L (no)	2006-02-01	Aztreonam-L-lysin og fremgangsmater for fremstilling av dette
SV2006002001A (es)	2006-02-15	Inhibidores de quinasa ref. x - 16437
ATE417849T1 (de)	2009-01-15	Pyrazoloä4,3-düpyrimidine
EA200601743A1 (ru)	2007-08-31	Выделенный полипептид реналазы и его применение