ATE417849T1 - Pyrazoloä4,3-düpyrimidine - Google Patents

Pyrazoloä4,3-düpyrimidine

Info

Publication number: ATE417849T1
Authority: AT; Austria
Prior art keywords: pyrazoloa4; düpyrimidine; compounds; formula; relates
Prior art date: 2004-04-07

Application number

AT05718362T

Other languages

English (en)

Inventor

Andrew Bell

David Brown

David Fox

Hwang-Fun Lu

Ian Marsh

Andrew Morrell

Dafydd Owen

Michael Palmer

Thomas Rogers

Carol Windslow

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-04-07

Filing date

2005-03-30

Publication date

2009-01-15

2004-04-07 Priority claimed from GB0407946A external-priority patent/GB0407946D0/en

2004-04-07 Priority claimed from GB0407927A external-priority patent/GB0407927D0/en

2005-03-30 Application filed by Pfizer filed Critical Pfizer

2009-01-15 Application granted granted Critical

2009-01-15 Publication of ATE417849T1 publication Critical patent/ATE417849T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Cardiology (AREA)
Urology & Nephrology (AREA)
Heart & Thoracic Surgery (AREA)
Reproductive Health (AREA)
Pulmonology (AREA)
Obesity (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Gynecology & Obstetrics (AREA)
Dermatology (AREA)
Hematology (AREA)
Hospice & Palliative Care (AREA)
Pregnancy & Childbirth (AREA)
Emergency Medicine (AREA)
Rheumatology (AREA)
Child & Adolescent Psychology (AREA)
Oncology (AREA)
Immunology (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT05718362T 2004-04-07 2005-03-30 Pyrazoloä4,3-düpyrimidine ATE417849T1 (de)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
GB0407946A GB0407946D0 (en)	2004-04-07	2004-04-07	Novel pharmaceuticals
GB0407927A GB0407927D0 (en)	2004-04-07	2004-04-07	Novel pharmaceuticals
US57202404P	2004-05-18	2004-05-18
US57204904P	2004-05-18	2004-05-18

Publications (1)

Publication Number	Publication Date
ATE417849T1 true ATE417849T1 (de)	2009-01-15

Family

ID=34962202

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT05718362T ATE417849T1 (de)	2004-04-07	2005-03-30	Pyrazoloä4,3-düpyrimidine

Country Status (10)

Country	Link
US (1)	US7569572B2 (de)
EP (1)	EP1742950B1 (de)
JP (1)	JP2007532526A (de)
AT (1)	ATE417849T1 (de)
BR (1)	BRPI0509731A (de)
CA (1)	CA2562251C (de)
DE (1)	DE602005011784D1 (de)
DK (1)	DK1742950T3 (de)
ES (1)	ES2317209T3 (de)
WO (1)	WO2005097799A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL126999A (en)	1996-07-24	2002-03-10	Warner Lambert Co	Pharmaceutical preparations containing isobutylgaba and its history for use in the treatment of pain
EA012577B1 (ru)	2005-05-12	2009-10-30	Пфайзер Инк.	БЕЗВОДНЫЕ КРИСТАЛЛИЧЕСКИЕ ФОРМЫ N-[1-(2-ЭТОКСИЭТИЛ)-5-(N-ЭТИЛ-N-МЕТИЛАМИНО)-7-(4-МЕТИЛПИРИДИН-2-ИЛАМИНО)-1Н-ПИРАЗОЛО[4,3-d]ПИРИМИДИН-3-КАРБОНИЛ]МЕТАНСУЛЬФОНАМИДА
NL2000291C2 (nl) *	2005-11-10	2009-02-17	Pfizer Prod Inc	1-(1-(2-ethoxyethyl)-3-ethyl-7-(4-methylpyridin-2-ylamino)-1H- pyrazool(4,3-d)pyrimidine-5-yl)piperidine-4-carbonzuur en zouten daarvan.
WO2010062308A1 (en) *	2008-10-28	2010-06-03	The Board Of Trustees Of The Leland Stanford Junior University	Modulators of aldehyde dehydrogenase and methods of use thereof
DE102008063992A1 (de) *	2008-12-19	2010-09-02	Lerner, Zinoviy, Dipl.-Ing.	Neue aliphatisch substituierte Pyrazolopyridine und ihre Verwendung
UY33535A (es)	2010-08-13	2011-12-01	Biolab Sanus Farmaceutuca Limitada	Derivados de 6,7-dihidro-3h-oxazolo[3,4]pirazin-5,8-diona
WO2012149106A1 (en)	2011-04-29	2012-11-01	The Board Of Trustees Of The Leland Stanford Junior University	Compositions and methods for increasing proliferation of adult salivary stem cells
US10709341B2 (en)	2012-11-21	2020-07-14	St. Jude Medical Luxembourg Holdings II S.a.r.l.	Devices, systems, and methods for pulmonary arterial hypertension (PAH) assessment and treatment
WO2014160185A2 (en)	2013-03-14	2014-10-02	The Board Of Trustees Of The Leland Stanford Junior University	Mitochondrial aldehyde dehydrogenase-2 modulators and methods of use thereof
WO2014145712A1 (en) *	2013-03-15	2014-09-18	Cardiomems, Inc.	Methods for the treatment of cardiovascular conditions
EP3140007A1 (de) *	2014-05-05	2017-03-15	Apicore US LLC	Verfahren zur herstellung von netupitant und zwischenprodukte davon

Family Cites Families (66)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3851980A (en) *	1974-04-19	1974-12-03	L Worth	Tubing connector
US3951980A (en)	1974-05-09	1976-04-20	Stanford Research Institute	3-Substituted-8-methyl-3,8-diazabicyclo[3.2.1]octanes
US4282361A (en) *	1978-03-16	1981-08-04	Massachusetts Institute Of Technology	Synthesis for 7-alkylamino-3-methylpyrazolo [4,3-d]pyrimidines
AU516604B2 (en)	1978-04-03	1981-06-11	Yoshida Kogyo K.K.	Tiltable roller assembly
JP3022967B2 (ja)	1985-03-15	2000-03-21	アンチバイラルズインコーポレイテッド	立体規則性ポリヌクレオチド結合ポリマー
US4812590A (en)	1987-06-25	1989-03-14	Merck & Co., Inc.	Carbamates of 4-hydroxyanisole as prodrugs for chemotherapy of melanoma
WO1989000158A1 (en)	1987-07-02	1989-01-12	Pfizer Inc.	Bridged-diazabicycloalkyl quinolone carboxylic acids and esters
GB8728483D0 (en)	1987-12-04	1988-01-13	Ciba Geigy Ag	Chemical compounds
US5091431A (en)	1988-02-08	1992-02-25	Schering Corporation	Phosphodiesterase inhibitors
US5075310A (en)	1988-07-01	1991-12-24	Smith Kline & French Laboratories, Ltd.	Pyrimidone derivatives as bronchodilators
FR2638745B1 (fr)	1988-11-08	1994-01-14	Synthelabo	Derives de ((n-alkylthioalkyl-methylamino)-2 ethyl)-5 benzothiazepine-1,5 one-4, leur preparation et leur application en therapeutique
US4994460A (en)	1989-06-01	1991-02-19	Bristol-Myers Squibb Co.	Agents for treatment of brain ischemia
JPH03142277A (ja)	1989-10-30	1991-06-18	Fuji Photo Film Co Ltd	記録材料
US5442044A (en)	1991-01-04	1995-08-15	Pfizer Inc.	Orally active renin inhibitors
DK0594702T3 (da)	1991-07-03	1997-07-21	Upjohn Co	Substituerede indoler som midler mod AIDS
GB9119704D0 (en)	1991-09-14	1991-10-30	Pfizer Ltd	Therapeutic agents
GB9121028D0 (en)	1991-10-03	1991-11-13	Pfizer Ltd	Therapeutic agents
GB9126260D0 (en)	1991-12-11	1992-02-12	Pfizer Ltd	Therapeutic agents
GB9213623D0 (en)	1992-06-26	1992-08-12	Pfizer Ltd	Therapeutic agents
JP2657760B2 (ja)	1992-07-15	1997-09-24	小野薬品工業株式会社	４−アミノキナゾリン誘導体およびそれを含有する医薬品
GB9218322D0 (en)	1992-08-28	1992-10-14	Pfizer Ltd	Therapeutic agents
GB9401090D0 (en)	1994-01-21	1994-03-16	Glaxo Lab Sa	Chemical compounds
GB9423911D0 (en)	1994-11-26	1995-01-11	Pfizer Ltd	Therapeutic agents
US5869486A (en)	1995-02-24	1999-02-09	Ono Pharmaceutical Co., Ltd.	Fused pyrimidines and pyriazines as pharmaceutical compounds
GB9518953D0 (en)	1995-09-15	1995-11-15	Pfizer Ltd	Pharmaceutical formulations
DE19644228A1 (de)	1996-10-24	1998-04-30	Merck Patent Gmbh	Thienopyrimidine
NZ338075A (en)	1997-04-25	2000-10-27	Pfizer Ltd	Pyrazolopyrimidinones which inhibit type 5 cyclic guanosine 3',5'-monophosphate phosphodiesterase (cGMP PED5) for the treatment of sexual dysfunction
US6184338B1 (en)	1997-08-27	2001-02-06	Fmc Corporation	Anionic polymerization initiators containing tertiary amine functionality, their chain extended analogues, and processes for using the same
EP2295436A1 (de)	1997-11-12	2011-03-16	Bayer Schering Pharma AG	2-Phenyl-substituierte Imidazotriazinone als Phosphodiesterase V Inhibitoren
DE19752952A1 (de)	1997-11-28	1999-06-02	Merck Patent Gmbh	Thienopyrimidine
CA2260499A1 (en)	1998-01-29	1999-07-29	Sumitomo Pharmaceuticals Company Limited	Pharmaceutical compositions for the treatment of ischemic brain damage
GB9804426D0 (en)	1998-03-02	1998-04-29	Pfizer Ltd	Heterocycles
ID27036A (id)	1998-04-20	2001-02-22	Pfizer	Pirazolopirimidinona penghambat cgmp pde5 untuk pengobatan kelainan fungsi seksual
BR9915532A (pt)	1998-10-23	2001-08-14	Pfizer	Inibidores de cgmp pde5 de pirazolopirimidinona para tratamento da disfunção sexual
CA2367130A1 (en)	1999-03-10	2000-09-14	Merck & Co., Inc.	6-azaindole compounds as antagonists of gonadotropin releasing hormone
US6465486B1 (en)	1999-03-12	2002-10-15	Ortho-Mcneil Pharmaceutical, Inc.	Pyridyl/quinolinyl imidazoles
GB9912415D0 (en)	1999-05-28	1999-07-28	Pfizer Ltd	Compounds useful in therapy
DE19942474A1 (de) *	1999-09-06	2001-03-15	Merck Patent Gmbh	Pyrazolo[4,3-d]pyrimidine
CZ20021086A3 (cs)	1999-09-30	2002-10-16	Neurogen Corporation	Alkylendiaminem substituované heterocykly
IL149025A0 (en)	1999-10-11	2002-11-10	Pfizer	5-(2-substituted-5-heterocyclylsulphonylpyrid-3-yl)-dihydropyrazolo [4, 3-d] pyrimidin-7-ones as phosphodiesterase inhibitors
TWI265925B (en)	1999-10-11	2006-11-11	Pfizer	Pyrazolo[4,3-d]pyrimidin-7-ones useful in inhibiting type 5 cyclic guanosine 3',5'-monophosphate phosphodiesterases(cGMP PDE5), process and intermediates for their preparation, their uses and composition comprising them
US6548509B2 (en)	1999-10-22	2003-04-15	Neurogen Corporation	3-aryl substituted pyrazolo[4,3-D]pyrimidine derivatives; corticotropin-releasing factor receptor (CRF1) specific ligands
GB9926302D0 (en)	1999-11-05	2000-01-12	Smithkline Beecham Plc	Novel compounds
GB9930570D0 (en)	1999-12-23	2000-02-16	Pfizer Ltd	Therapy
JP2003518485A (ja)	1999-12-23	2003-06-10	ファイザー・プロダクツ・インク	向上された薬物濃度を与える医薬組成物
JP2003519232A (ja)	2000-01-07	2003-06-17	ウニフェルジテーレ・インステリング・アントウェルペン	プリン誘導体、その製造法およびその使用
US20010047013A1 (en)	2000-03-10	2001-11-29	Fengrui Lang	Process for the preparation of arylamines
DE10031584A1 (de)	2000-06-29	2002-01-10	Merck Patent Gmbh	5-Aminoalkyl-pyrazolo[4,3-d]pyrimidine
YU51701A (sh)	2000-07-28	2003-12-31	Pfizer Inc.	Postupak za dobijanje jedinjenja pirazola/4,3-d/ pirimidin-7-ona i njihovih derivata
PT1305314E (pt)	2000-07-28	2005-04-29	Pfizer	Agente terapeutico cristalino
EP1176142A1 (de)	2000-07-28	2002-01-30	Pfizer Inc.	Verfahren zur Herstellung von Pyrazolen
KR20030023747A (ko)	2000-08-11	2003-03-19	화이자 인코포레이티드	인슐린 저항성 증후군의 치료
CA2429605A1 (en)	2000-11-20	2002-05-30	Scios Inc.	Indol derivative and their use as inhibitors of p38 kinase
DE10058662A1 (de)	2000-11-25	2002-05-29	Merck Patent Gmbh	Verwendung von Pyrazolo[4,3-d]pyrimidinen
AU2002229573A1 (en)	2000-12-19	2002-07-01	Merck Patent Gmbh	Pharmaceutical formulation containing pyrazolo(4,3-D)pyrimidines and antithrombotic agents, calcium-antagonists, prostaglandins or prostaglandin derivatives
CZ20032339A3 (cs)	2001-01-31	2004-09-15	Merck Patent Gmbh	Farmaceutický prostředek obsahující parazolo [4,3-d]pyrimidiny a nitráty nebo thienopyrimidiny a nitráty
GB0103926D0 (en)	2001-02-17	2001-04-04	Astrazeneca Ab	Chemical compounds
JP2002255932A (ja)	2001-03-01	2002-09-11	Katayama Seiyakushiyo:Kk	３−アルキルアミノアゼチジンの製造方法
US20020127593A1 (en)	2001-03-12	2002-09-12	Regents Of The University Of California	Fluorescence assay for DNA modifying enzymes
GB0106631D0 (en)	2001-03-16	2001-05-09	Pfizer Ltd	Pharmaceutically active compounds
PE20030008A1 (es)	2001-06-19	2003-01-22	Bristol Myers Squibb Co	Inhibidores duales de pde 7 y pde 4
US6432957B1 (en)	2001-06-29	2002-08-13	Kowa Co., Ltd.	Piperazine derivative
CA2479037C (en)	2002-03-15	2010-11-09	Jiri Zemlicka	2-amino-9[(2-hydroxymethyl)cyclopropylidenemethyl]purines as antiviral agents
EP1348707B1 (de)	2002-03-28	2010-08-25	Ustav Experimentalni Botaniky AV CR, v.v.i. (Institute of Experimental Botany Academy of Sciences of the Czech Republic, PRO)	Pyrazolo[4,3-d]pyrimidine, Verfahren zu ihrer Herstellung und therapeutische Anwendung
US7505971B2 (en)	2002-06-28	2009-03-17	Hewlett-Packard Development Company, L.P.	Shared drive that provides shared access to editable files in a database
MXPA05011643A (es)	2003-04-29	2005-12-15	Pfizer Ltd	5,7-diaminopirazolo[4,3-d]pirimidinas en el tratamiento de hipertension.

2005
- 2005-03-30 JP JP2007506858A patent/JP2007532526A/ja not_active Withdrawn
- 2005-03-30 DK DK05718362T patent/DK1742950T3/da active
- 2005-03-30 ES ES05718362T patent/ES2317209T3/es active Active
- 2005-03-30 AT AT05718362T patent/ATE417849T1/de not_active IP Right Cessation
- 2005-03-30 BR BRPI0509731-2A patent/BRPI0509731A/pt not_active IP Right Cessation
- 2005-03-30 CA CA002562251A patent/CA2562251C/en not_active Expired - Fee Related
- 2005-03-30 WO PCT/IB2005/000891 patent/WO2005097799A1/en active Application Filing
- 2005-03-30 US US10/599,702 patent/US7569572B2/en not_active Expired - Fee Related
- 2005-03-30 DE DE602005011784T patent/DE602005011784D1/de not_active Expired - Fee Related
- 2005-03-30 EP EP05718362A patent/EP1742950B1/de not_active Not-in-force

Also Published As

Publication number	Publication date
CA2562251A1 (en)	2005-10-20
DK1742950T3 (da)	2009-03-16
US7569572B2 (en)	2009-08-04
EP1742950A1 (de)	2007-01-17
ES2317209T3 (es)	2009-04-16
WO2005097799A8 (en)	2006-02-16
DE602005011784D1 (de)	2009-01-29
EP1742950B1 (de)	2008-12-17
WO2005097799A1 (en)	2005-10-20
JP2007532526A (ja)	2007-11-15
CA2562251C (en)	2009-04-28
BRPI0509731A (pt)	2007-09-25
US20080293697A1 (en)	2008-11-27

Publication	Publication Date	Title
CY1109911T1 (el)	2014-09-10	Πυρρολοβενζοδιαζεπινες
UY29612A1 (es)	2007-01-31	Compuestos quimicos ii
CY1112467T1 (el)	2015-12-09	Παραγωγα 1-θειο-d-γλυκιτολης
EA201001359A1 (ru)	2011-04-29	Гетероциклические соединения в качестве ингибиторов cxcr2
NO20060202L (no)	2006-01-13	Pyrrolodihydroisokinoliner som PDE-10-inhibitorer
TW200626559A (en)	2006-08-01	Anilino-pyrimidine analogs
EA201790678A1 (ru)	2017-12-29	Бициклические гетероарильные соединения
TW200626610A (en)	2006-08-01	Analogs of 17-hydroxywortmannin as PI3K inhibitors
EA200801428A1 (ru)	2008-10-30	Производные пиридиазинона для лечения опухолей
WO2007085895A3 (en)	2008-04-17	Fap inhibitors
ES2338590T3 (es)	2010-05-10	Procedimiento regioselectivo de preparacion de benzoimidazoltiofenos.
DK1853602T3 (da)	2010-09-20	Kemiske forbindelser
DK1853588T3 (da)	2008-09-15	Kemiske forbindelser
MX342683B (es)	2016-10-07	Analogos de ciclopamina.
EA200801608A1 (ru)	2008-10-30	Производные бензимидазолонкарбоновой кислоты
EA200701396A1 (ru)	2007-12-28	Триазолофталазины в качестве ингибиторов pde-2
EA201000566A1 (ru)	2010-12-30	Гетероциклические сетр ингибиторы
EA200801145A1 (ru)	2008-10-30	Спироциклические производные хиназолина в качестве ингибиторов pde7
EA200801365A1 (ru)	2008-10-30	Замещенные 5-фенил-3,6-дигидро-2-оксо-6h-1,3,4-тиадиазины
EA200801366A1 (ru)	2008-10-30	Производные 3,6-дигидро-2-оксо-6н-1,3,4-тиадиазина
EA201270256A1 (ru)	2012-07-30	Производные т1-замещенного 5-фтор-2-оксопиримидинон-1 (2h) -карбоксамида
EA200801549A1 (ru)	2008-10-30	Новые производные фенантридина в качестве антагонистов брадикинина
DE602006006544D1 (de)	2009-06-10	Neue pyrrolodihydroisochinoline als pde10-inhibitoren
EA200700365A1 (ru)	2007-06-29	Производные индол-2-карбоксамидина как антагонисты nmda рецептора
EA201000069A1 (ru)	2011-02-28	Новые гербициды

Legal Events

Date	Code	Title	Description
2009-06-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties