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DK165749C - Grf-analoge peptider og farmaceutisk acceptable salte heraf samt farmaceutisk middel indeholdende disse - Google Patents

Grf-analoge peptider og farmaceutisk acceptable salte heraf samt farmaceutisk middel indeholdende disse

Info

Publication number
DK165749C
DK165749C DK433684A DK433684A DK165749C DK 165749 C DK165749 C DK 165749C DK 433684 A DK433684 A DK 433684A DK 433684 A DK433684 A DK 433684A DK 165749 C DK165749 C DK 165749C
Authority
DK
Denmark
Prior art keywords
pharmaceutical
acceptable salts
substances containing
analogue peptides
grf analogue
Prior art date
Application number
DK433684A
Other languages
English (en)
Other versions
DK165749B (da
DK433684A (da
DK433684D0 (da
Inventor
Jean Edouard Frederic Rivier
Jr Wylie Walker Vale
Original Assignee
Salk Inst For Biological Studi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Salk Inst For Biological Studi filed Critical Salk Inst For Biological Studi
Publication of DK433684D0 publication Critical patent/DK433684D0/da
Publication of DK433684A publication Critical patent/DK433684A/da
Publication of DK165749B publication Critical patent/DK165749B/da
Application granted granted Critical
Publication of DK165749C publication Critical patent/DK165749C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/60Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/142Amino acids; Derivatives thereof
    • A23K20/147Polymeric derivatives, e.g. peptides or proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00Peptide or protein sequence
    • Y10S930/01Peptide or protein sequence
    • Y10S930/12Growth hormone, growth factor other than t-cell or b-cell growth factor, and growth hormone releasing factor; related peptides

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Polymers & Plastics (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Husbandry (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK433684A 1983-09-13 1984-09-11 Grf-analoge peptider og farmaceutisk acceptable salte heraf samt farmaceutisk middel indeholdende disse DK165749C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US53217083A 1983-09-13 1983-09-13
US53217083 1983-09-13
US54509483 1983-10-25
US06/545,094 US4518586A (en) 1983-01-13 1983-10-25 GRF Analogs III

Publications (4)

Publication Number Publication Date
DK433684D0 DK433684D0 (da) 1984-09-11
DK433684A DK433684A (da) 1985-03-14
DK165749B DK165749B (da) 1993-01-11
DK165749C true DK165749C (da) 1993-06-14

Family

ID=27063766

Family Applications (1)

Application Number Title Priority Date Filing Date
DK433684A DK165749C (da) 1983-09-13 1984-09-11 Grf-analoge peptider og farmaceutisk acceptable salte heraf samt farmaceutisk middel indeholdende disse

Country Status (21)

Country Link
US (1) US4518586A (da)
EP (1) EP0146210B1 (da)
JP (1) JPH0689035B2 (da)
AU (1) AU577057B2 (da)
CA (1) CA1271599A (da)
DE (1) DE3462603D1 (da)
DK (1) DK165749C (da)
ES (1) ES8600217A1 (da)
FI (1) FI88402C (da)
GR (1) GR80335B (da)
HU (1) HU200192B (da)
IE (1) IE57774B1 (da)
IL (1) IL72799A (da)
IN (1) IN160247B (da)
MX (1) MX161018A (da)
NO (1) NO166944C (da)
NZ (1) NZ209515A (da)
PH (1) PH22310A (da)
PT (1) PT79189B (da)
SU (1) SU1435157A3 (da)
YU (1) YU45968B (da)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4728726A (en) * 1982-10-04 1988-03-01 The Salk Institute For Biological Studies GRF analogs IIIb
AU575843B2 (en) * 1983-08-10 1988-08-11 The Administrators Of The Tulane Eductional Fund Growth hormone releasing peptides
US4626523A (en) * 1983-09-13 1986-12-02 The Salk Institute For Biological Studies GRF analogs II
US4617149A (en) * 1983-09-21 1986-10-14 Eli Lilly And Company Growth hormone release factor analogs
US4528190A (en) * 1983-10-25 1985-07-09 The Salk Institute For Biological Studies GRF Analogs IV
US4649131A (en) * 1984-09-24 1987-03-10 Hoffmann-La Roche Inc. Growth hormone releasing factor analogs
CA1271600A (en) * 1985-01-07 1990-07-10 David Howard Coy Growth hormone-releasing peptides and method of treating mammals therewith
EP0193910A3 (en) * 1985-03-06 1988-11-23 Sumitomo Pharmaceuticals Company, Limited Synthesis of a derivative of grf and intermediate peptides
US4734399A (en) * 1985-08-06 1988-03-29 Hoffmann-La Roche Inc. Growth hormone releasing factor analogs
DK382886A (da) * 1985-08-12 1987-02-13 Syntex Inc Fremgangsmaade til fremstilling af hormonfaktorderivater
US4689318A (en) * 1985-08-29 1987-08-25 The Salk Institute For Biological Studies GRF analogs
US4870054A (en) * 1985-09-27 1989-09-26 Recker Robert R Treatment for osteoporosis using GRF or a biologically active analog thereof
US4880778A (en) * 1986-05-12 1989-11-14 Eastman Kodak Company Combinations having synergistic growth hormone releasing activity and methods for use thereof
IL84758A (en) * 1987-01-13 1992-03-29 Salk Inst For Biological Studi Peptides stimulating the release of pituitary growth hormone in fish and amphibians,and pharmaceutical compositions containing them
IL86102A (en) * 1987-05-11 1994-04-12 Univ Tulane Alkylated peptides that release growth hormone and their use
US5002931A (en) * 1987-05-22 1991-03-26 The Salk Institute For Biological Studies GRF analogs VII
US4839344A (en) * 1987-06-12 1989-06-13 Eastman Kodak Company Polypeptide compounds having growth hormone releasing activity
USRE33699E (en) * 1987-07-09 1991-09-24 International Minerals & Chemical Corp. Growth hormone-releasing factor analogs
US4801456A (en) * 1987-07-09 1989-01-31 International Minerals & Chemical Corp. Growth hormone-releasing factor analogs
US4880777A (en) * 1987-09-01 1989-11-14 Eastman Kodak Company Synthetic peptides having growth hormone releasing activity
EP0400051B1 (en) * 1988-01-28 1995-05-10 Polygen Holding Corporation Polypeptide compounds having growth hormone releasing activity
US5043322A (en) * 1988-07-22 1991-08-27 The Salk Institute For Biological Studies Cyclic GRF analogs
US5023322A (en) * 1988-08-31 1991-06-11 Mta Kutatas-Es Szervezetelemzo Intezete Analogs of growth hormone releasing factor (GRF) and a method for the preparation thereof
US5756458A (en) * 1989-06-16 1998-05-26 Pharmacia & Upjohn Company Stabilized potent GRF analogs
EP0544706A4 (en) * 1990-06-29 1993-10-13 Hoffmann-La Roche Inc. Histidine substituted growth hormone releasing factor analogs
ATE119916T1 (de) * 1990-12-10 1995-04-15 Hoffmann La Roche Verfahren zur enzymatischen herstellung von grf(1-44)nh2.
JPH05507939A (ja) * 1991-04-09 1993-11-11 エフ・ホフマン―ラ ロシユ アーゲー 成長ホルモン放出因子の類似体
US5246920A (en) * 1992-06-15 1993-09-21 University Of South Florida Treatment of hyperprolactinemia
US5811074A (en) * 1992-06-29 1998-09-22 University Of South Florida Method of diagnosing pituitary dependent growth hormone deficiency
US5550212A (en) * 1993-12-17 1996-08-27 The Administrators Of The Tulane Educational Fund Analogues of hGH-RH(1-29)NH2 having antagonistic activity
JP2004520395A (ja) * 2001-02-02 2004-07-08 コンジュケム,インコーポレーテッド 長期持続性成長ホルモン放出因子誘導体
MXPA05002991A (es) * 2002-09-18 2005-10-05 Univ Montreal Ct Hospitalier Chum Analogos de ghrh.
JP5649825B2 (ja) 2007-01-31 2015-01-07 デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド 安定化させたp53ペプチドおよびその使用法
CA2682174C (en) 2007-03-28 2021-04-06 President And Fellows Of Harvard College Stitched polypeptides
WO2009009727A2 (en) * 2007-07-12 2009-01-15 Akela Pharma Srl Ghrh analogs and therapeutic uses thereof
PL2603600T3 (pl) 2010-08-13 2019-06-28 Aileron Therapeutics, Inc. Makrocykle peptidomometyczne
WO2012142706A1 (en) 2011-04-21 2012-10-26 Theratechnologies Inc. Growth hormone releasing factor (grf) analogs and uses thereof
AR088392A1 (es) 2011-10-18 2014-05-28 Aileron Therapeutics Inc Macrociclos peptidomimeticos
CN104144695A (zh) 2012-02-15 2014-11-12 爱勒让治疗公司 三唑交联的和硫醚交联的拟肽大环化合物
RU2017145921A (ru) 2012-02-15 2019-02-21 Эйлерон Терапьютикс, Инк. Пептидомиметические макроциклы
KR20150082307A (ko) 2012-11-01 2015-07-15 에일러론 테라퓨틱스 인코포레이티드 이치환 아미노산 및 이의 제조 및 사용 방법
SG10201902594QA (en) 2014-09-24 2019-04-29 Aileron Therapeutics Inc Peptidomimetic macrocycles and uses thereof
KR20170129879A (ko) 2015-03-20 2017-11-27 에일러론 테라퓨틱스 인코포레이티드 펩티드모방 거대고리 및 이의 용도

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ204456A (en) * 1982-06-16 1987-05-29 Salk Inst For Biological Studi Synthetic pancreatic growth-hormone releasing factor
IL70530A (en) * 1983-01-13 1986-09-30 Salk Inst For Biological Studi Synthetic peptides having growth hormone releasing factor activity and compositions containing them
ZA841638B (en) * 1983-03-07 1984-10-31 Hoffmann La Roche Polypeptides
AU575843B2 (en) * 1983-08-10 1988-08-11 The Administrators Of The Tulane Eductional Fund Growth hormone releasing peptides
PT79094B (en) * 1983-08-29 1986-08-14 Salk Inst For Biological Studi Grf analogs

Also Published As

Publication number Publication date
EP0146210B1 (en) 1987-03-11
JPH0689035B2 (ja) 1994-11-09
HU200192B (en) 1990-04-28
AU577057B2 (en) 1988-09-15
PT79189B (en) 1986-08-14
MX161018A (es) 1990-07-05
JPS60100596A (ja) 1985-06-04
IL72799A0 (en) 1984-11-30
IL72799A (en) 1987-10-30
ES535846A0 (es) 1985-10-01
NO166944C (no) 1991-09-18
FI843579A0 (fi) 1984-09-12
CA1271599A (en) 1990-07-10
US4518586A (en) 1985-05-21
NZ209515A (en) 1988-08-30
DK165749B (da) 1993-01-11
IE842324L (en) 1985-03-13
DK433684A (da) 1985-03-14
DK433684D0 (da) 1984-09-11
PT79189A (en) 1984-10-01
YU157984A (en) 1988-04-30
IE57774B1 (en) 1993-04-07
FI843579L (fi) 1985-03-14
ES8600217A1 (es) 1985-10-01
DE3462603D1 (en) 1987-04-16
FI88402B (fi) 1993-01-29
GR80335B (en) 1985-01-11
PH22310A (en) 1988-07-22
NO166944B (no) 1991-06-10
FI88402C (fi) 1993-05-10
YU45968B (sh) 1992-12-21
AU3259484A (en) 1985-03-21
SU1435157A3 (ru) 1988-10-30
EP0146210A1 (en) 1985-06-26
NO843592L (no) 1985-03-14
HUT35696A (en) 1985-07-29
IN160247B (da) 1987-07-04

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Legal Events

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PUP Patent expired