DK164899C - Analogifremgangsmaade til fremstilling af 2-substituerede-3-hydroxy-1,4-naphthoquinoner og udgangsmaterialer til brug ved fremgangsmaaden - Google Patents
Analogifremgangsmaade til fremstilling af 2-substituerede-3-hydroxy-1,4-naphthoquinoner og udgangsmaterialer til brug ved fremgangsmaadenInfo
- Publication number
- DK164899C DK164899C DK459682A DK459682A DK164899C DK 164899 C DK164899 C DK 164899C DK 459682 A DK459682 A DK 459682A DK 459682 A DK459682 A DK 459682A DK 164899 C DK164899 C DK 164899C
- Authority
- DK
- Denmark
- Prior art keywords
- procedure
- naphthoquinones
- hydroxy
- substituted
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C61/16—Unsaturated compounds
- C07C61/22—Unsaturated compounds having a carboxyl group bound to a six-membered ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C46/00—Preparation of quinones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C50/00—Quinones
- C07C50/24—Quinones containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C50/00—Quinones
- C07C50/26—Quinones containing groups having oxygen atoms singly bound to carbon atoms
- C07C50/32—Quinones containing groups having oxygen atoms singly bound to carbon atoms the quinoid structure being part of a condensed ring system having two rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/08—Preparation of carboxylic acids or their salts, halides or anhydrides from nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/353—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by isomerisation; by change of size of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/36—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by hydrogenation of carbon-to-carbon unsaturated bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
- C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
- C07C53/132—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen containing rings
- C07C53/134—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen containing rings monocyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C61/08—Saturated compounds having a carboxyl group bound to a six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C61/15—Saturated compounds containing halogen
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Ophthalmology & Optometry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8131206 | 1981-10-16 | ||
GB8131206 | 1981-10-16 |
Publications (3)
Publication Number | Publication Date |
---|---|
DK459682A DK459682A (da) | 1983-04-17 |
DK164899B DK164899B (da) | 1992-09-07 |
DK164899C true DK164899C (da) | 1993-02-01 |
Family
ID=10525197
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK459682A DK164899C (da) | 1981-10-16 | 1982-10-15 | Analogifremgangsmaade til fremstilling af 2-substituerede-3-hydroxy-1,4-naphthoquinoner og udgangsmaterialer til brug ved fremgangsmaaden |
Country Status (8)
Country | Link |
---|---|
US (1) | US4485117A (da) |
EP (1) | EP0077551B1 (da) |
JP (2) | JPS5879945A (da) |
CA (1) | CA1205083A (da) |
DE (1) | DE3264133D1 (da) |
DK (1) | DK164899C (da) |
GB (1) | GB2107713B (da) |
IT (1) | IT1200943B (da) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5053432A (en) * | 1983-04-14 | 1991-10-01 | Burroughs Wellcome Co. | Naphthoquinone derivatives |
GB8310140D0 (en) * | 1983-04-14 | 1983-05-18 | Wellcome Found | Antiprotozoal agents |
US5175319A (en) * | 1983-04-14 | 1992-12-29 | Burroughs Wellcome Co. | Naphthoquinone derivatives |
US5225436A (en) * | 1987-05-15 | 1993-07-06 | Schering Corporation | Aryl substituted naphthalene derivatives |
US5225184A (en) * | 1988-08-16 | 1993-07-06 | Burroughs Wellcome Co. | Medicaments |
GB8819477D0 (en) * | 1988-08-16 | 1988-09-21 | Wellcome Found | Medicaments |
US5206268A (en) * | 1988-08-16 | 1993-04-27 | Burroughs Wellcome Co. | Medicaments |
CA1329621C (en) * | 1988-08-16 | 1994-05-17 | Victoria Susan Latter | Naphthoquinones in the treatment or prophylaxis of pneumocystis carinii infections |
GB9216859D0 (en) * | 1992-08-07 | 1992-09-23 | Wellcome Found | Medicaments |
GB9224739D0 (en) | 1992-11-26 | 1993-01-13 | Wellcome Found | Medicaments |
GB9226905D0 (en) | 1992-12-24 | 1993-02-17 | Wellcome Found | Pharmaceutical preparation |
US5684035A (en) * | 1996-07-17 | 1997-11-04 | Kapadia; Govind J. | Antimalarial agents |
CA2504388A1 (en) * | 2002-10-31 | 2004-05-13 | State Of Israel, Ministry Of Agriculture | Quinazolinone compositions for regulation of gene expression related to pathological processes |
US7900577B2 (en) * | 2004-04-27 | 2011-03-08 | Hewlett-Packard Development Company, L.P. | System and a method for starch-based, slow-release oral dosage forms |
ITMI20070941A1 (it) * | 2007-05-09 | 2008-11-10 | Chimico Internazi0Nale S P A L | Procedimento per la preparazione di naftochinoni trans2,3-disostituiti |
EP2250145A4 (en) * | 2008-03-07 | 2012-02-22 | Alkem Lab Ltd | PREPARATION OF NAPHTHOCHINONE COMPOUNDS USING 2,3-DIHALONAPHOCHINONE |
EP2307343A1 (en) * | 2008-06-30 | 2011-04-13 | Chemagis Ltd. | Process for the epimerization of atovaquone isomer, atovaquone intermediates and mixture thereof |
WO2012153162A1 (en) * | 2011-05-12 | 2012-11-15 | Lupin Limited | Novel method for preparation of atovaquone |
US8975438B2 (en) * | 2011-07-13 | 2015-03-10 | Hoffmann-La Roche Inc. | Process for the preparation of cyclohexanecarboxylic acid derivatives |
JP2014162752A (ja) * | 2013-02-25 | 2014-09-08 | Dic Corp | 化合物、液晶組成物、及び表示装置 |
CN114956972B (zh) * | 2022-05-12 | 2024-10-18 | 沧州东恩科技有限公司 | 一种布帕伐醌的合成新方法 |
CN116874360B (zh) * | 2023-09-06 | 2023-11-24 | 世华合创生物技术开发(山东)有限公司 | 一种布帕伐醌的合成方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2553647A (en) * | 1946-03-20 | 1951-05-22 | Research Corp | Naphthoquinone antimalarials |
US2553648A (en) | 1948-01-08 | 1951-05-22 | Research Corp | Naphthoquinone compounds |
US3347742A (en) * | 1965-05-28 | 1967-10-17 | Merck & Co Inc | 2-(4-cyclohexylcyclohexyl)-3-hydroxy-1, 4-naphthoquinone in controlling coccidiosis in poultry |
US3393211A (en) * | 1965-09-14 | 1968-07-16 | Merck & Co Inc | Naphthoquinone compounds |
DE1553666A1 (de) * | 1967-11-18 | 1971-09-16 | Balco Filtertechnik Gmbh | Scherfolie fuer Trockenrasierer |
US3578686A (en) * | 1968-04-26 | 1971-05-11 | Sterling Drug Inc | 2-hydroxy - 3 -((3,3,5-trimethylcyclohexyl)-alkyl) - 1,4-naphthoquinones and their preparation |
US4110473A (en) * | 1977-07-14 | 1978-08-29 | E. I. Du Pont De Nemours And Company | Miticidal ethers |
IL56013A (en) * | 1977-11-22 | 1983-06-15 | Wellcome Found | 2-cycloalkyl-3-hydroxy-1,4-naphthoquinone derivatives,their preparation and therapeutic compositions containing them |
-
1982
- 1982-10-13 US US06/433,867 patent/US4485117A/en not_active Expired - Lifetime
- 1982-10-15 DK DK459682A patent/DK164899C/da active
- 1982-10-15 JP JP57181220A patent/JPS5879945A/ja active Granted
- 1982-10-15 GB GB08229501A patent/GB2107713B/en not_active Expired
- 1982-10-15 DE DE8282109569T patent/DE3264133D1/de not_active Expired
- 1982-10-15 CA CA000413584A patent/CA1205083A/en not_active Expired
- 1982-10-15 IT IT49275/82A patent/IT1200943B/it active
- 1982-10-15 EP EP82109569A patent/EP0077551B1/en not_active Expired
-
1991
- 1991-07-23 JP JP3182337A patent/JPH0672122B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JPS5879945A (ja) | 1983-05-13 |
JPH051250B2 (da) | 1993-01-07 |
DK164899B (da) | 1992-09-07 |
CA1205083A (en) | 1986-05-27 |
IT1200943B (it) | 1989-01-27 |
JPH0597765A (ja) | 1993-04-20 |
US4485117A (en) | 1984-11-27 |
JPH0672122B2 (ja) | 1994-09-14 |
DK459682A (da) | 1983-04-17 |
EP0077551A3 (en) | 1983-09-14 |
DE3264133D1 (en) | 1985-07-18 |
EP0077551B1 (en) | 1985-06-12 |
GB2107713B (en) | 1985-10-23 |
EP0077551A2 (en) | 1983-04-27 |
GB2107713A (en) | 1983-05-05 |
IT8249275A0 (it) | 1982-10-15 |
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