DK1638468T3 - Fremgangsmåde til coating af hudpiercingmikrofremspring - Google Patents
Fremgangsmåde til coating af hudpiercingmikrofremspringInfo
- Publication number
- DK1638468T3 DK1638468T3 DK04756456T DK04756456T DK1638468T3 DK 1638468 T3 DK1638468 T3 DK 1638468T3 DK 04756456 T DK04756456 T DK 04756456T DK 04756456 T DK04756456 T DK 04756456T DK 1638468 T3 DK1638468 T3 DK 1638468T3
- Authority
- DK
- Denmark
- Prior art keywords
- skin piercing
- micro projections
- coating skin
- piercing micro
- projections
- Prior art date
Links
- 239000011248 coating agent Substances 0.000 title 1
- 238000000576 coating method Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/20—Surgical instruments, devices or methods for vaccinating or cleaning the skin previous to the vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/20—Surgical instruments, devices or methods for vaccinating or cleaning the skin previous to the vaccination
- A61B17/205—Vaccinating by means of needles or other puncturing devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0053—Methods for producing microneedles
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Dermatology (AREA)
- Medical Informatics (AREA)
- Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Materials For Medical Uses (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US48414203P | 2003-06-30 | 2003-06-30 | |
PCT/US2004/021076 WO2005004729A1 (en) | 2003-06-30 | 2004-06-29 | Method for coating skin piercing microprojections |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1638468T3 true DK1638468T3 (da) | 2007-12-17 |
Family
ID=34062028
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK04756456T DK1638468T3 (da) | 2003-06-30 | 2004-06-29 | Fremgangsmåde til coating af hudpiercingmikrofremspring |
Country Status (18)
Country | Link |
---|---|
US (1) | US20040265365A1 (da) |
EP (1) | EP1638468B1 (da) |
JP (1) | JP5174347B2 (da) |
KR (1) | KR20060029162A (da) |
CN (1) | CN100586385C (da) |
AR (1) | AR044963A1 (da) |
AT (1) | ATE369802T1 (da) |
AU (1) | AU2004255228A1 (da) |
BR (1) | BRPI0412021A (da) |
CA (1) | CA2530520A1 (da) |
DE (1) | DE602004008278T2 (da) |
DK (1) | DK1638468T3 (da) |
ES (1) | ES2290738T3 (da) |
MX (1) | MXPA06000283A (da) |
PL (1) | PL1638468T3 (da) |
PT (1) | PT1638468E (da) |
TW (1) | TW200514591A (da) |
WO (1) | WO2005004729A1 (da) |
Families Citing this family (79)
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GB0210397D0 (en) | 2002-05-07 | 2002-06-12 | Ferring Bv | Pharmaceutical formulations |
MXPA06000281A (es) * | 2003-06-30 | 2006-07-03 | Johnson & Johnson | Formulaciones para microproyecciones revestidas que contienen contraiones no volatiles. |
JP2007503268A (ja) | 2003-08-25 | 2007-02-22 | スリーエム イノベイティブ プロパティズ カンパニー | 免疫応答修飾化合物の送達 |
JP5388415B2 (ja) * | 2003-11-13 | 2014-01-15 | アルザ・コーポレーシヨン | 経皮送達のための組成物及び装置 |
WO2005103303A2 (en) * | 2004-04-13 | 2005-11-03 | Alza Corporation | Apparatus and method for transdermal delivery of multiple vaccines |
CA2566032A1 (en) | 2004-05-13 | 2005-12-01 | Alza Corporation | Apparatus and method for transdermal delivery of parathyroid hormone agents |
US20060030811A1 (en) * | 2004-08-03 | 2006-02-09 | Wong Patrick S | Method and device for enhancing transdermal agent flux |
CN101232874A (zh) * | 2004-08-11 | 2008-07-30 | 阿尔扎公司 | 透皮递送利钠肽的装置和方法 |
SE0402100D0 (sv) * | 2004-08-30 | 2004-08-30 | Bonsens Ab | Molded micro-needles |
JP5015787B2 (ja) * | 2004-11-18 | 2012-08-29 | スリーエム イノベイティブ プロパティズ カンパニー | マイクロニードルアレイの接触コーティング法 |
US8057842B2 (en) * | 2004-11-18 | 2011-11-15 | 3M Innovative Properties Company | Method of contact coating a microneedle array |
US20060188555A1 (en) * | 2005-01-21 | 2006-08-24 | Micheal Cormier | Therapeutic peptide formulations with improved stability |
US20060177494A1 (en) * | 2005-01-31 | 2006-08-10 | Micheal Cormier | Coated microprojections having reduced variability and method for producing same |
CN101160117A (zh) * | 2005-02-16 | 2008-04-09 | 阿尔扎公司 | 依泊汀-基药物的透皮释放装置和方法 |
EP1898807A1 (en) * | 2005-03-28 | 2008-03-19 | Alza Corporation | Microprojections with capillary control features and method |
EP1893130A4 (en) | 2005-06-17 | 2015-08-26 | Georgia Tech Res Inst | COATED MICROSTRUCTURES AND METHOD FOR THE PRODUCTION THEREOF |
US20070078414A1 (en) * | 2005-08-05 | 2007-04-05 | Mcallister Devin V | Methods and devices for delivering agents across biological barriers |
WO2007033015A1 (en) * | 2005-09-12 | 2007-03-22 | Alza Corporation | Coatable transdermal delivery microprojection assembly |
WO2007061781A1 (en) * | 2005-11-18 | 2007-05-31 | 3M Innovative Properties Company | Coatable compositions, coatings derived therefrom and microarrays having such coatings |
US8554317B2 (en) * | 2005-11-30 | 2013-10-08 | 3M Innovative Properties Company | Microneedle arrays and methods of use thereof |
EP1981547B1 (en) * | 2005-12-28 | 2015-09-30 | Alza Corporation | Stable therapeutic formulations |
US20070202186A1 (en) | 2006-02-22 | 2007-08-30 | Iscience Interventional Corporation | Apparatus and formulations for suprachoroidal drug delivery |
CA2680690A1 (en) * | 2006-03-15 | 2007-09-20 | Alza Corporation | Apparatus and method for transdermal delivery of parathyroid hormone agents to prevent or treat osteopenia |
US20070224252A1 (en) * | 2006-03-27 | 2007-09-27 | Trautman Joseph C | Microprojections with capillary control features and method |
US8197435B2 (en) * | 2006-05-02 | 2012-06-12 | Emory University | Methods and devices for drug delivery to ocular tissue using microneedle |
WO2007131050A2 (en) * | 2006-05-02 | 2007-11-15 | Georgia Tech Research Corporation | Method for drug delivery to ocular tissue using microneedle |
JP5090032B2 (ja) * | 2007-03-20 | 2012-12-05 | 凸版印刷株式会社 | 針状体および針状体製造方法 |
JP5297595B2 (ja) * | 2007-03-20 | 2013-09-25 | 凸版印刷株式会社 | 針状体および針状体製造方法 |
EP2146689B1 (en) | 2007-04-16 | 2020-08-12 | Corium, Inc. | Solvent-cast microneedle arrays containing active |
AU2014200648B2 (en) * | 2007-04-16 | 2015-09-24 | Corium Pharma Solutions, Inc. | Solvent-cast microneedle arrays containing active |
US8911749B2 (en) | 2007-04-16 | 2014-12-16 | Corium International, Inc. | Vaccine delivery via microneedle arrays |
JP2008284318A (ja) * | 2007-05-15 | 2008-11-27 | Kosumedei Seiyaku Kk | 生体由来物質からなる投薬用微細針 |
WO2009037566A2 (en) * | 2007-06-19 | 2009-03-26 | Uvarkina Tamara P | Hyaluronidase and method of use thereof |
EP2011629A1 (de) * | 2007-07-03 | 2009-01-07 | F. Hoffman-la Roche AG | Verfahren zur Herstellung eines mikrofluiden Systems auf einer Polymeroberfläche |
CA2988753A1 (en) | 2007-08-06 | 2009-02-12 | Serenity Pharmaceuticals, Llc | Methods and devices for desmopressin drug delivery |
JP5504632B2 (ja) * | 2008-03-05 | 2014-05-28 | セイコーエプソン株式会社 | 電気泳動装置、電気泳動装置の駆動方法、電子機器 |
US20100286045A1 (en) | 2008-05-21 | 2010-11-11 | Bjarke Mirner Klein | Methods comprising desmopressin |
US11963995B2 (en) | 2008-05-21 | 2024-04-23 | Ferring B.V. | Methods comprising desmopressin |
PT3225250T (pt) | 2008-05-21 | 2019-10-15 | Ferring Bv | Desmopressina orodispersivel para aumentar o periodo inicial de sono não perturbado pela nocturia |
CN102039000B (zh) * | 2009-10-20 | 2015-08-26 | 苏州纳通生物纳米技术有限公司 | 一种透皮给药试剂盒 |
US9687641B2 (en) | 2010-05-04 | 2017-06-27 | Corium International, Inc. | Method and device for transdermal delivery of parathyroid hormone using a microprojection array |
WO2012051575A2 (en) | 2010-10-15 | 2012-04-19 | Iscience Interventional Corporation | Device for ocular access |
US20140066842A1 (en) * | 2011-03-07 | 2014-03-06 | 3M Innovative Properties Company | Microneedle devices and methods |
AU2012328448B2 (en) * | 2011-10-28 | 2017-02-02 | Sung-Yun Kwon | Dissolving solid solution perforator patch for migraine treatment |
CN104080441B (zh) | 2011-11-30 | 2020-02-28 | 3M创新有限公司 | 包括肽治疗剂和氨基酸的微针装置、制备和使用其的方法 |
JP5472771B1 (ja) | 2012-09-28 | 2014-04-16 | コスメディ製薬株式会社 | 段差に薬物を保持したマイクロニードル |
KR20150083117A (ko) | 2012-11-08 | 2015-07-16 | 클리어사이드 바이오메디컬, 인코포레이드 | 인간 대상체에서 안구 질병을 치료하기 위한 방법 및 장치 |
MX375307B (es) | 2012-12-21 | 2025-03-06 | Corium Inc | Microarreglo para la entrega de agente terapeutico y metodos de uso. |
AU2014249471B2 (en) | 2013-03-12 | 2019-01-24 | Corium Pharma Solutions, Inc. | Microprojection applicators |
US9962534B2 (en) | 2013-03-15 | 2018-05-08 | Corium International, Inc. | Microarray for delivery of therapeutic agent, methods of use, and methods of making |
ES2908339T3 (es) | 2013-03-15 | 2022-04-28 | Corium Inc | Micromatriz para el suministro de un agente terapéutico y métodos de uso |
CA2903763C (en) | 2013-03-15 | 2021-11-16 | Corium International, Inc. | Microarray with polymer-free microstructures, methods of making, and methods of use |
AU2014237357B2 (en) | 2013-03-15 | 2019-11-28 | Corium Pharma Solutions, Inc. | Multiple impact microprojection applicators and methods of use |
AU2014259694B2 (en) | 2013-05-03 | 2018-11-08 | Clearside Biomedical, Inc. | Apparatus and methods for ocular injection |
EP3003454B1 (en) | 2013-06-03 | 2020-01-08 | Clearside Biomedical, Inc. | Apparatus for drug delivery using multiple reservoirs |
KR20160052590A (ko) * | 2013-09-06 | 2016-05-12 | 히사미쓰 세이야꾸 가부시키가이샤 | 마이크로 니들·시트 |
CN103611214A (zh) * | 2013-12-03 | 2014-03-05 | 上海交通大学 | 针药微系统及其制备方法 |
JP6325082B2 (ja) * | 2014-02-27 | 2018-05-16 | 久光製薬株式会社 | マイクロニードル・シート |
CA2952958A1 (en) | 2014-06-20 | 2015-12-23 | Clearside Biomedical, Inc. | Variable diameter cannula and methods for controlling insertion depth for medicament delivery |
US10624843B2 (en) | 2014-09-04 | 2020-04-21 | Corium, Inc. | Microstructure array, methods of making, and methods of use |
USD750223S1 (en) | 2014-10-14 | 2016-02-23 | Clearside Biomedical, Inc. | Medical injector for ocular injection |
WO2016088886A1 (ja) | 2014-12-05 | 2016-06-09 | 久光製薬株式会社 | マイクロニードルデバイスシステム |
CN108135177B (zh) | 2015-04-29 | 2021-06-01 | 雷迪厄斯制药公司 | 用于治疗癌症的方法 |
WO2017004067A1 (en) | 2015-06-29 | 2017-01-05 | Corium International, Inc. | Microarray for delivery of therapeutic agent, methods of use, and methods of making |
US10390901B2 (en) | 2016-02-10 | 2019-08-27 | Clearside Biomedical, Inc. | Ocular injection kit, packaging, and methods of use |
EP3452165A1 (en) | 2016-05-02 | 2019-03-13 | Clearside Biomedical, Inc. | Systems and methods for ocular drug delivery |
WO2017204418A1 (ko) * | 2016-05-23 | 2017-11-30 | 주식회사유한양행 | 사마귀 치료를 위한 블레오마이신을 함유하는 마이크로니들 패치 및 이의 제작방법 |
WO2018026955A1 (en) * | 2016-08-03 | 2018-02-08 | Verndari, Inc. | Microarrays and methods |
IL305537B2 (en) | 2016-08-12 | 2025-02-01 | Clearside Biomedical Inc | Devices and methods for adjusting the insertion depth of a needle for administering a drug |
WO2018124290A1 (ja) | 2016-12-28 | 2018-07-05 | コスメディ製薬株式会社 | 薬剤を塗布したマイクロニードルアレイ |
KR101947624B1 (ko) * | 2016-12-29 | 2019-02-14 | 랩앤피플주식회사 | 멀티형 마이크로 니들 |
US20190224462A1 (en) * | 2016-12-29 | 2019-07-25 | Labnpeople Co., Ltd. | Microneedle array |
CN110191707A (zh) | 2017-01-05 | 2019-08-30 | 雷迪厄斯制药公司 | Rad1901-2hcl的多晶型形式 |
WO2018204515A1 (en) | 2017-05-02 | 2018-11-08 | Georgia Tech Research Corporation | Targeted drug delivery methods using a microneedle |
WO2019111959A1 (ja) * | 2017-12-05 | 2019-06-13 | 古河電気工業株式会社 | 機能性部材及びその製造方法 |
KR102022968B1 (ko) * | 2018-01-12 | 2019-09-19 | 주식회사 에스엔비아 | 마이크로 니들 시트 구조 및 그 제조방법 |
SG11202013177WA (en) | 2018-07-04 | 2021-01-28 | Radius Pharmaceuticals Inc | Polymorphic forms of rad 1901-2hcl |
JP7399295B2 (ja) * | 2020-04-06 | 2023-12-15 | イルロン カンパニー リミテッド | 化粧品吸収誘導用微細針が取り付けられた化粧品注入器及びその制作方法 |
WO2023042889A1 (ja) | 2021-09-15 | 2023-03-23 | コスメディ製薬株式会社 | 薬剤を塗布したマイクロニードルアレイ |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
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US3136314A (en) * | 1960-08-01 | 1964-06-09 | Kravitz Harvey | Vaccinating devices |
US3351059A (en) * | 1964-06-02 | 1967-11-07 | Norman Lettvin | Single stable dose vaccinator |
US3964482A (en) * | 1971-05-17 | 1976-06-22 | Alza Corporation | Drug delivery device |
BE795384A (fr) * | 1972-02-14 | 1973-08-13 | Ici Ltd | Pansements |
OA05448A (fr) * | 1975-10-16 | 1981-03-31 | Manufrance Manufacture Francai | Dispositif vaccinateur multipénétrant. |
FR2474856A1 (fr) * | 1980-01-31 | 1981-08-07 | Merieux Inst | Dispositif scarificateur |
EP0429842B1 (en) * | 1989-10-27 | 1996-08-28 | Korea Research Institute Of Chemical Technology | Device for the transdermal administration of protein or peptide drug |
US5279544A (en) * | 1990-12-13 | 1994-01-18 | Sil Medics Ltd. | Transdermal or interdermal drug delivery devices |
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AU5740496A (en) * | 1995-05-22 | 1996-12-11 | General Hospital Corporation, The | Micromechanical device and method for enhancing delivery of compounds through the skin |
ATE221400T1 (de) * | 1997-12-11 | 2002-08-15 | Alza Corp | Vorrichtung zur erhöhung des transdermalen wirkstoffeflusses |
DK1037686T3 (da) * | 1997-12-11 | 2006-01-02 | Alza Corp | Apparat til forögelse af transdermal gennemströmning af midler |
JPH11249287A (ja) * | 1998-03-05 | 1999-09-17 | Matsushita Electric Works Ltd | 印刷版用材、印刷版、製版方法および印刷装置 |
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WO1999064580A1 (en) * | 1998-06-10 | 1999-12-16 | Georgia Tech Research Corporation | Microneedle devices and methods of manufacture and use thereof |
JP2000034677A (ja) * | 1998-07-15 | 2000-02-02 | Dainippon Printing Co Ltd | 部分親水性シート |
ATE428466T1 (de) * | 2000-10-26 | 2009-05-15 | Alza Corp | Transdermales arzneistoffverabreichungssytem mit beschichteten mikrovorsprüngen |
US6663820B2 (en) * | 2001-03-14 | 2003-12-16 | The Procter & Gamble Company | Method of manufacturing microneedle structures using soft lithography and photolithography |
JP2004528900A (ja) * | 2001-04-20 | 2004-09-24 | アルザ・コーポレーシヨン | 有益な作用物質を含有するコーティングを有する微小突起アレイ |
MXPA06000281A (es) * | 2003-06-30 | 2006-07-03 | Johnson & Johnson | Formulaciones para microproyecciones revestidas que contienen contraiones no volatiles. |
-
2004
- 2004-06-29 MX MXPA06000283A patent/MXPA06000283A/es unknown
- 2004-06-29 ES ES04756456T patent/ES2290738T3/es not_active Expired - Lifetime
- 2004-06-29 PT PT04756456T patent/PT1638468E/pt unknown
- 2004-06-29 KR KR1020057025473A patent/KR20060029162A/ko not_active Application Discontinuation
- 2004-06-29 WO PCT/US2004/021076 patent/WO2005004729A1/en active IP Right Grant
- 2004-06-29 DE DE602004008278T patent/DE602004008278T2/de not_active Expired - Lifetime
- 2004-06-29 DK DK04756456T patent/DK1638468T3/da active
- 2004-06-29 AU AU2004255228A patent/AU2004255228A1/en not_active Abandoned
- 2004-06-29 AT AT04756456T patent/ATE369802T1/de not_active IP Right Cessation
- 2004-06-29 JP JP2006518743A patent/JP5174347B2/ja not_active Expired - Fee Related
- 2004-06-29 BR BRPI0412021-3A patent/BRPI0412021A/pt not_active IP Right Cessation
- 2004-06-29 PL PL04756456T patent/PL1638468T3/pl unknown
- 2004-06-29 CN CN200480024388A patent/CN100586385C/zh not_active Expired - Fee Related
- 2004-06-29 US US10/880,701 patent/US20040265365A1/en not_active Abandoned
- 2004-06-29 CA CA002530520A patent/CA2530520A1/en not_active Abandoned
- 2004-06-29 EP EP04756456A patent/EP1638468B1/en not_active Expired - Lifetime
- 2004-06-30 TW TW093119233A patent/TW200514591A/zh unknown
- 2004-06-30 AR ARP040102299A patent/AR044963A1/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
PL1638468T3 (pl) | 2008-01-31 |
WO2005004729A1 (en) | 2005-01-20 |
AR044963A1 (es) | 2005-10-12 |
DE602004008278T2 (de) | 2008-02-14 |
BRPI0412021A (pt) | 2006-08-15 |
JP2007521090A (ja) | 2007-08-02 |
ES2290738T3 (es) | 2008-02-16 |
DE602004008278D1 (de) | 2007-09-27 |
TW200514591A (en) | 2005-05-01 |
EP1638468B1 (en) | 2007-08-15 |
CN100586385C (zh) | 2010-02-03 |
CN1842300A (zh) | 2006-10-04 |
AU2004255228A1 (en) | 2005-01-20 |
KR20060029162A (ko) | 2006-04-04 |
PT1638468E (pt) | 2007-10-10 |
MXPA06000283A (es) | 2006-07-03 |
CA2530520A1 (en) | 2005-01-20 |
JP5174347B2 (ja) | 2013-04-03 |
US20040265365A1 (en) | 2004-12-30 |
ATE369802T1 (de) | 2007-09-15 |
EP1638468A1 (en) | 2006-03-29 |
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