DK163177A - Fremgangsmade til fremstilling af bis-kvartere pyridinium-2-aldoximsalte - Google Patents
Fremgangsmade til fremstilling af bis-kvartere pyridinium-2-aldoximsalteInfo
- Publication number
- DK163177A DK163177A DK163177A DK163177A DK163177A DK 163177 A DK163177 A DK 163177A DK 163177 A DK163177 A DK 163177A DK 163177 A DK163177 A DK 163177A DK 163177 A DK163177 A DK 163177A
- Authority
- DK
- Denmark
- Prior art keywords
- aldoxim
- quarters
- pyridinium
- bis
- salts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/53—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19762616481 DE2616481A1 (de) | 1976-04-14 | 1976-04-14 | Bis-quartaere pyridinium-2-aldoxim- salze und verfahren zu ihrer herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK163177A true DK163177A (da) | 1977-10-15 |
Family
ID=5975404
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK163177A DK163177A (da) | 1976-04-14 | 1977-04-13 | Fremgangsmade til fremstilling af bis-kvartere pyridinium-2-aldoximsalte |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4128651A (da) |
| JP (1) | JPS52128381A (da) |
| AT (1) | AT361923B (da) |
| BE (1) | BE853570A (da) |
| CA (1) | CA1070307A (da) |
| CH (1) | CH627745A5 (da) |
| DE (1) | DE2616481A1 (da) |
| DK (1) | DK163177A (da) |
| ES (1) | ES457791A1 (da) |
| FR (1) | FR2348211A1 (da) |
| GB (1) | GB1516626A (da) |
| IE (1) | IE44737B1 (da) |
| IL (1) | IL51857A (da) |
| NL (1) | NL7704030A (da) |
| SE (1) | SE7704240L (da) |
| ZA (1) | ZA772253B (da) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT365410B (de) * | 1978-08-31 | 1982-01-11 | Ciba Geigy Ag | Mittel zum schutz von kulturpflanzen vor aggressi-ven herbiziden |
| NL7905789A (nl) | 1979-07-26 | 1981-01-28 | Tno | 1-gesubstitueerde-hydroxyiminomethyl-pyridinium zouten, werkwijze voor het bereiden van deze verbindingen, preparaten tegen organo-fosfaatvergiftingingen, alsmede werkwijze voor het bereiden van dergelijke preparaten. |
| DE3332272A1 (de) * | 1983-09-07 | 1985-03-21 | Bayer Ag, 5090 Leverkusen | Herbizide mittel enthaltend metribuzin in kombination mit pyridincarbonsaeureamiden |
| IL72788A (en) * | 1984-08-28 | 1989-07-31 | Israel State | Bis quaternary oxy-bis methylene(or trimethylene)bis-n-quinuclidines,pyridines and piperidines,their preparation and antidotes against organophosphorus and carbamate poisoning containing them |
| US5130438A (en) * | 1985-11-20 | 1992-07-14 | The United States Of America As Represented By The Secretary Of The Army | Bis-methylene ether pyridinium compound preparation |
| US5760049A (en) * | 1997-02-21 | 1998-06-02 | Synapse Pharmaceuticals International, Inc. | Method for controlling tobacco use and alleviating withdrawal symptoms due to cessation of tobacco use |
| US7414135B2 (en) * | 2005-02-17 | 2008-08-19 | Aerojet Fine Chemicals Llc | Process for halomethyl ethers of hydroxyiminomethyl quaternary pyridinium salts |
| US20060247281A1 (en) * | 2005-02-17 | 2006-11-02 | Aerojet Fine Chemicals Llc, A Delaware Limited Liability Company | Process for halomethyl ethers of hydroxyiminomethyl quaternary pyridinium salts |
| US8946200B2 (en) * | 2006-11-02 | 2015-02-03 | Southwest Research Institute | Pharmaceutically active nanosuspensions |
| US8404850B2 (en) * | 2008-03-13 | 2013-03-26 | Southwest Research Institute | Bis-quaternary pyridinium-aldoxime salts and treatment of exposure to cholinesterase inhibitors |
| US8722706B2 (en) * | 2008-08-15 | 2014-05-13 | Southwest Research Institute | Two phase bioactive formulations of bis-quaternary pyridinium oxime sulfonate salts |
| US8309134B2 (en) * | 2008-10-03 | 2012-11-13 | Southwest Research Institute | Modified calcium phosphate nanoparticle formation |
| US9028873B2 (en) * | 2010-02-08 | 2015-05-12 | Southwest Research Institute | Nanoparticles for drug delivery to the central nervous system |
| WO2011142826A1 (en) * | 2010-05-12 | 2011-11-17 | Mississipi State University | Phenoxyalkyl pyridinium oxime therapeutics for treatment of organophosphate poisoning |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3773775A (en) * | 1968-08-27 | 1973-11-20 | Merck Patent Gmbh | Bis-quaternary pyridinium salts |
-
1976
- 1976-04-14 DE DE19762616481 patent/DE2616481A1/de not_active Withdrawn
-
1977
- 1977-04-08 FR FR7710729A patent/FR2348211A1/fr active Granted
- 1977-04-11 IL IL51857A patent/IL51857A/xx unknown
- 1977-04-11 US US05/786,693 patent/US4128651A/en not_active Expired - Lifetime
- 1977-04-13 CH CH459277A patent/CH627745A5/de not_active IP Right Cessation
- 1977-04-13 GB GB15341/77A patent/GB1516626A/en not_active Expired
- 1977-04-13 SE SE7704240A patent/SE7704240L/xx not_active Application Discontinuation
- 1977-04-13 NL NL7704030A patent/NL7704030A/xx not_active Application Discontinuation
- 1977-04-13 ZA ZA00772253A patent/ZA772253B/xx unknown
- 1977-04-13 DK DK163177A patent/DK163177A/da not_active IP Right Cessation
- 1977-04-13 AT AT257077A patent/AT361923B/de not_active IP Right Cessation
- 1977-04-13 CA CA276,042A patent/CA1070307A/en not_active Expired
- 1977-04-13 IE IE759/77A patent/IE44737B1/en unknown
- 1977-04-14 BE BE2055827A patent/BE853570A/xx unknown
- 1977-04-14 ES ES457791A patent/ES457791A1/es not_active Expired
- 1977-04-14 JP JP4342577A patent/JPS52128381A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ATA257077A (de) | 1980-09-15 |
| FR2348211B1 (da) | 1980-04-18 |
| IE44737L (en) | 1977-10-14 |
| DE2616481A1 (de) | 1977-11-03 |
| ES457791A1 (es) | 1978-08-01 |
| ZA772253B (en) | 1978-03-29 |
| IL51857A (en) | 1980-05-30 |
| FR2348211A1 (fr) | 1977-11-10 |
| JPS52128381A (en) | 1977-10-27 |
| SE7704240L (sv) | 1977-10-15 |
| GB1516626A (en) | 1978-07-05 |
| US4128651A (en) | 1978-12-05 |
| AT361923B (de) | 1981-04-10 |
| CH627745A5 (de) | 1982-01-29 |
| NL7704030A (nl) | 1977-10-18 |
| IE44737B1 (en) | 1982-03-10 |
| BE853570A (fr) | 1977-10-14 |
| IL51857A0 (en) | 1977-06-30 |
| CA1070307A (en) | 1980-01-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHS | Application shelved for other reasons than non-payment | ||
| PBP | Patent lapsed |