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DK161325C - Analogifremgangsmaade til fremstilling af imidazooe4,5-caa-pyridinderivater - Google Patents

Analogifremgangsmaade til fremstilling af imidazooe4,5-caa-pyridinderivater

Info

Publication number
DK161325C
DK161325C DK499582A DK499582A DK161325C DK 161325 C DK161325 C DK 161325C DK 499582 A DK499582 A DK 499582A DK 499582 A DK499582 A DK 499582A DK 161325 C DK161325 C DK 161325C
Authority
DK
Denmark
Prior art keywords
imidazooe4
caa
preparing
pyridine derivatives
analogy procedure
Prior art date
Application number
DK499582A
Other languages
Danish (da)
English (en)
Other versions
DK161325B (da
DK499582A (da
Inventor
William Richard King
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of DK499582A publication Critical patent/DK499582A/da
Publication of DK161325B publication Critical patent/DK161325B/da
Application granted granted Critical
Publication of DK161325C publication Critical patent/DK161325C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK499582A 1981-11-10 1982-11-09 Analogifremgangsmaade til fremstilling af imidazooe4,5-caa-pyridinderivater DK161325C (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB8133930 1981-11-10
GB8133930 1981-11-10
GB8133942 1981-11-10
GB8133942 1981-11-10
GB8213846 1982-05-12
GB8213846 1982-05-12

Publications (3)

Publication Number Publication Date
DK499582A DK499582A (da) 1983-05-11
DK161325B DK161325B (da) 1991-06-24
DK161325C true DK161325C (da) 1991-12-02

Family

ID=27261362

Family Applications (1)

Application Number Title Priority Date Filing Date
DK499582A DK161325C (da) 1981-11-10 1982-11-09 Analogifremgangsmaade til fremstilling af imidazooe4,5-caa-pyridinderivater

Country Status (17)

Country Link
US (1) US4603139A (fi)
EP (1) EP0079083B1 (fi)
KR (1) KR890000022B1 (fi)
AR (1) AR241247A1 (fi)
AU (1) AU9030682A (fi)
DD (1) DD205904A5 (fi)
DK (1) DK161325C (fi)
ES (2) ES517193A0 (fi)
FI (1) FI79312C (fi)
GB (1) GB2113675B (fi)
GR (1) GR76746B (fi)
IE (1) IE56478B1 (fi)
IL (1) IL67206A0 (fi)
MC (1) MC1491A1 (fi)
NO (1) NO158100C (fi)
PH (1) PH22764A (fi)
PT (1) PT75820B (fi)

Families Citing this family (78)

* Cited by examiner, † Cited by third party
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DE3273461D1 (en) * 1981-08-19 1986-10-30 Merck Patent Gmbh 2-arylimidazopyridines
IL68495A0 (en) * 1982-05-03 1983-07-31 Lilly Co Eli 2-phenylimidazo(4,5-c)pyridines
US4904785A (en) * 1982-05-03 1990-02-27 Eli Lilly And Company 2-phenylimidazo[4,5-c]pyridines
US4758574A (en) * 1982-05-03 1988-07-19 Eli Lilly And Company 2-phenylimidazio (4,5-c) pyridines
DE3224512A1 (de) * 1982-07-01 1984-01-05 Dr. Karl Thomae Gmbh, 7950 Biberach Neue imidazolderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel
DE3324115A1 (de) * 1983-07-05 1985-01-17 Dr. Karl Thomae Gmbh, 7950 Biberach Neue imidazole, ihre herstellung und diese verbindungen enthaltende arzneimittel
US4515796A (en) * 1983-09-08 1985-05-07 Eli Lilly And Company Certain naphthalenyl imidazo compounds and their pharmaceutical use
US4533734A (en) * 1983-11-10 1985-08-06 Eli Lilly And Company Inotropic agents
DE3346602A1 (de) * 1983-12-23 1985-07-11 Dr. Karl Thomae Gmbh, 7950 Biberach Neue imidazo(4,5-c)pyridin-one, deren herstellung und diese verbindungen enthaltende arzneimittel
DE3347290A1 (de) * 1983-12-28 1985-07-11 Dr. Karl Thomae Gmbh, 7950 Biberach Neue 2-phenyl-imidazole, ihre herstellung und diese verbindungen enthaltende arzneimittel
ZA851236B (en) * 1984-02-24 1986-09-24 Lilly Co Eli 2-arylimidazo 4,5-cpyridines
US4578387A (en) * 1984-03-05 1986-03-25 Eli Lilly And Company Inotropic agents
DE3445299A1 (de) * 1984-12-12 1986-06-19 Dr. Karl Thomae Gmbh, 7950 Biberach Neue imidazoderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
CA1295330C (en) * 1985-03-29 1992-02-04 James M. Greene Synthesis of inotropic imidazo(4,5-c) pyridine
DE3522230A1 (de) * 1985-06-21 1987-01-02 Thomae Gmbh Dr K Neue 2-arylimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
US4740599A (en) * 1986-10-03 1988-04-26 Eli Lilly And Company Synthesis of alkylsulfinyl substituted 2-phenylimidazo(4,5-c)pyridines
ZA889365B (en) * 1987-12-22 1990-08-29 Lilly Co Eli Hydrates of andinotropic agent
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DE4324580A1 (de) * 1993-07-22 1995-01-26 Thomae Gmbh Dr K Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
EP0912568B1 (en) * 1996-05-15 2002-11-20 ALTANA Pharma AG imidazopyridines
DE59711147D1 (de) * 1996-11-11 2004-01-29 Altana Pharma Ag Neue Imidazo- und Oxazolopyridine als Phosphodiesterase Inhibitoren.
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KR20060087386A (ko) * 2005-01-28 2006-08-02 주식회사 대웅제약 신규 벤조이미다졸 유도체 및 이를 함유하는 약제학적조성물
WO2007034277A1 (en) * 2005-09-19 2007-03-29 Pfizer Products Inc. Aryl substituted imidazo [4,5-c] pyridine compounds as c3a receptor antagonists
RU2539568C2 (ru) 2008-10-31 2015-01-20 Дженентек, Инк. Пиразолопиримидиновые соединения-ингибиторы jak и способы
UA110324C2 (en) 2009-07-02 2015-12-25 Genentech Inc Jak inhibitory compounds based on pyrazolo pyrimidine
EP2987487B1 (en) * 2009-08-10 2020-10-07 Samumed, LLC Indazole inhibitors of the wnt signal pathway and therapeutic uses thereof
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JP2013542966A (ja) 2010-11-19 2013-11-28 エフ．ホフマン−ラ ロシュ アーゲー ピラゾロピリジンならびにｔｙｋ２阻害剤としてのピラゾロピリジン及びそれらの使用
MX390742B (es) 2011-09-14 2025-03-21 Samumed Llc Indazol-3-carboxamidas y su uso como inhibidores de la trayectoria de señalizacion de wnt/b-catenina.
PH12017500997A1 (en) 2012-04-04 2018-02-19 Samumed Llc Indazole inhibitors of the wnt signal pathway and therapeutic uses thereof
PT2770994T (pt) 2012-05-04 2019-11-04 Samumed Llc 1h-pirazolo[3,4-b]piridinas e utilizações terapêuticas destas
EP2943198B1 (en) 2013-01-08 2019-07-17 Samumed, LLC 3-(benzoimidazol-2-yl)-indazole inhibitors of the wnt signaling pathway and therapeutic uses thereof
EP2818472A1 (en) * 2013-06-27 2014-12-31 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Imidazo[4,5-c]pyridine and pyrrolo[3,2-c]pyridine compounds as G-protein-coupled receptor kinase 5 (GRK5) modulators
US11229208B2 (en) 2013-07-02 2022-01-25 Syngenta Participations Ag Pesticidally active bi- or tricyclic heterocycles with sulfur containing substituents
CN107652292B (zh) * 2013-07-02 2020-11-17 先正达参股股份有限公司 有杀有害生物活性的具有含硫取代基的二环或三环杂环
JP6677637B2 (ja) * 2013-07-02 2020-04-08 シンジェンタ パーティシペーションズ アーゲー 有害生物防除的に活性な、硫黄含有置換基を有する二環式または三環式複素環
ES2987367T3 (es) * 2014-02-17 2024-11-14 Bayer Cropscience Ag Derivados de heterociclos bicíclicos condensados sustituidos con 2-(het)arilo como agentes para combatir parásitos
JP2017516850A (ja) 2014-05-23 2017-06-22 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ Ｊａｋ阻害剤である５−クロロ−２−ジフルオロメトキシフェニルピラゾロピリミジン化合物
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WO2016040182A1 (en) 2014-09-08 2016-03-17 Samumed, Llc 2-(1h-indazol-3-yl)-1h-imidazo[4,5-c]pyridine and therapeutic uses thereof
WO2016040185A1 (en) 2014-09-08 2016-03-17 Samumed, Llc 2-(1h-indazol-3-yl)-3h-imidazo[4,5-b]pyridine and therapeutic uses thereof
WO2016040184A1 (en) 2014-09-08 2016-03-17 Samumed, Llc 3-(3h-imidazo[4,5-b]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof
WO2016040193A1 (en) 2014-09-08 2016-03-17 Samumed, Llc 3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridine and therapeutic uses thereof
WO2016040181A1 (en) 2014-09-08 2016-03-17 Samumed, Llc 3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof
WO2016040180A1 (en) 2014-09-08 2016-03-17 Samumed, Llc 3-(1h-benzo[d]imidazol-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof
WO2016058928A1 (en) * 2014-10-14 2016-04-21 Syngenta Participations Ag Pesticidally active heterocyclic derivatives with sulphur containing substituents
CN107001365B (zh) * 2014-12-17 2019-09-24 先正达参股股份有限公司 具有含硫取代基的杀有害生物活性杂环衍生物
US10385048B2 (en) * 2014-12-31 2019-08-20 Syngenta Participation Ag Pesticidally active polycyclic derivatives with sulfur containing substituents
UY36547A (es) * 2015-02-05 2016-06-01 Bayer Cropscience Ag Derivados heterocíclicos condensados bicíclicos sustituidos por 2-(het)arilo como pesticidas
US10285982B2 (en) 2015-08-03 2019-05-14 Samumed, Llc 3-(1H-pyrrolo[2,3-B]pyridin-2-yl)-1H-pyrazolo[3,4-C]pyridines and therapeutic uses thereof
WO2017024015A1 (en) 2015-08-03 2017-02-09 Samumed, Llc. 3-(3h-imidazo[4,5-b]pyridin-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof
US10285983B2 (en) 2015-08-03 2019-05-14 Samumed, Llc 3-(1H-pyrrolo[2,3-B]pyridin-2-yl)-1H-pyrazolo[3,4-B] pyridines and therapeutic uses thereof
US10206908B2 (en) 2015-08-03 2019-02-19 Samumed, Llc 3-(1H-pyrrolo[3,2-C]pyridin-2-YL)-1H-pyrazolo[3,4-C]pyridines and therapeutic uses thereof
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WO2017023987A1 (en) 2015-08-03 2017-02-09 Samumed, Llc. 3-(1h-pyrrolo[3,2-c]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridines and therapeutic uses thereof
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HUE060797T2 (hu) 2016-06-01 2023-04-28 Biosplice Therapeutics Inc Eljárás N-(5-(3-(7-(3-fluorfenil)-3H-imidazo[4,5-c]piridin-2-il)-1H-indazol-5-il)- piridin-3-il)-3-metilbutánamid elõállítására
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CA820316A (en) * 1969-08-12 Fisons Pest Control Limited Substituted heterocyclic compounds
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Also Published As

Publication number Publication date
DK161325B (da) 1991-06-24
PH22764A (en) 1988-12-12
DK499582A (da) 1983-05-11
ES8401486A1 (es) 1983-12-01
PT75820A (en) 1982-12-01
FI79312B (fi) 1989-08-31
DD205904A5 (de) 1984-01-11
US4603139A (en) 1986-07-29
NO158100C (no) 1988-07-13
KR890000022B1 (ko) 1989-03-06
NO158100B (no) 1988-04-05
ES523083A0 (es) 1985-02-16
PT75820B (en) 1986-06-11
FI79312C (fi) 1989-12-11
EP0079083A1 (en) 1983-05-18
IL67206A0 (en) 1983-03-31
FI823846A0 (fi) 1982-11-09
GR76746B (fi) 1984-08-30
AR241247A1 (es) 1992-03-31
EP0079083B1 (en) 1991-02-27
FI823846L (fi) 1983-05-11
IE56478B1 (en) 1991-08-14
KR840002398A (ko) 1984-07-02
NO823732L (no) 1983-05-11
IE822667L (en) 1983-05-10
GB2113675A (en) 1983-08-10
ES8503351A1 (es) 1985-02-16
AU9030682A (en) 1983-05-19
MC1491A1 (fr) 1983-09-12
ES517193A0 (es) 1983-12-01
GB2113675B (en) 1985-10-30

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