DK158443C - Fremgangsmaade til stabilisering af et lyophiliseret praeparat indeholdende et alkalimetalsalt af en 7beta-(alfa-carboxy-alfa-arylacetamido)-7alfa-methoxy-3-heterocyklisk thiomethyl-1-dethia-1-oxa-3-cephem-4-carboxylsyre - Google Patents

Fremgangsmaade til stabilisering af et lyophiliseret praeparat indeholdende et alkalimetalsalt af en 7beta-(alfa-carboxy-alfa-arylacetamido)-7alfa-methoxy-3-heterocyklisk thiomethyl-1-dethia-1-oxa-3-cephem-4-carboxylsyre

Info

Publication number: DK158443C
Authority: DK; Denmark
Prior art keywords: alfa; heterocyliclyl; 7alfa; thly; arylacetamido
Prior art date: 1980-06-23

Application number

DK274981A

Other languages

Danish (da)

English (en)

Other versions

DK158443B (da

DK274981A (da

Inventor

Kazuhiro Shima

Eizo Hirai

Original Assignee

Shionogi & Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-06-23

Filing date

1981-06-22

Publication date

1990-10-08

1981-06-22 Application filed by Shionogi & Co filed Critical Shionogi & Co

1981-12-24 Publication of DK274981A publication Critical patent/DK274981A/da

1990-05-21 Publication of DK158443B publication Critical patent/DK158443B/da

1990-10-08 Application granted granted Critical

1990-10-08 Publication of DK158443C publication Critical patent/DK158443C/da

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Oil, Petroleum & Natural Gas (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Dermatology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Cephalosporin Compounds (AREA)

DK274981A 1980-06-23 1981-06-22 Fremgangsmaade til stabilisering af et lyophiliseret praeparat indeholdende et alkalimetalsalt af en 7beta-(alfa-carboxy-alfa-arylacetamido)-7alfa-methoxy-3-heterocyklisk thiomethyl-1-dethia-1-oxa-3-cephem-4-carboxylsyre DK158443C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP8578980		1980-06-23
JP8578980A JPS5711909A (en)	1980-06-23	1980-06-23	Stable freeze-dried preparation of beta-lactam

Publications (3)

Publication Number	Publication Date
DK274981A DK274981A (da)	1981-12-24
DK158443B DK158443B (da)	1990-05-21
DK158443C true DK158443C (da)	1990-10-08

Family

ID=13868648

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK274981A DK158443C (da)	1980-06-23	1981-06-22	Fremgangsmaade til stabilisering af et lyophiliseret praeparat indeholdende et alkalimetalsalt af en 7beta-(alfa-carboxy-alfa-arylacetamido)-7alfa-methoxy-3-heterocyklisk thiomethyl-1-dethia-1-oxa-3-cephem-4-carboxylsyre

Country Status (31)

Country	Link
US (1)	US4418058A (nl)
JP (1)	JPS5711909A (nl)
KR (1)	KR840000693B1 (nl)
AR (1)	AR230007A1 (nl)
AT (1)	AT380790B (nl)
AU (1)	AU541627B2 (nl)
BE (1)	BE889351A (nl)
BG (1)	BG37991A3 (nl)
CA (1)	CA1164801A (nl)
CH (1)	CH648210A5 (nl)
CS (1)	CS221835B2 (nl)
DD (1)	DD159879A5 (nl)
DE (1)	DE3124592A1 (nl)
DK (1)	DK158443C (nl)
ES (1)	ES8203887A1 (nl)
FI (1)	FI75490C (nl)
FR (1)	FR2484835A1 (nl)
GB (1)	GB2078737B (nl)
GR (1)	GR75646B (nl)
HU (1)	HU183494B (nl)
IE (1)	IE51331B1 (nl)
IL (1)	IL63136A (nl)
IT (1)	IT1144812B (nl)
NL (1)	NL191777C (nl)
NO (1)	NO156036C (nl)
NZ (1)	NZ197414A (nl)
PT (1)	PT73239B (nl)
RO (1)	RO82720B (nl)
SE (1)	SE460702B (nl)
YU (1)	YU44416B (nl)
ZA (1)	ZA814203B (nl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS597193A (ja) *	1982-07-02	1984-01-14	Shionogi & Co Ltd	マロニルメチル基の異性化方法
JPS6045514A (ja) *	1983-08-22	1985-03-12	Shionogi & Co Ltd	安定な抗菌性凍結乾燥製剤
US4797388A (en) *	1984-05-21	1989-01-10	Cetus Corporation	Pharmaceutical compositions with galactitol as carrier
US4891391A (en) *	1985-01-03	1990-01-02	Morton Thiokol, Inc.	Compositions containing antimicrobial agents in combination with stabilizers
US4816568A (en) *	1986-05-16	1989-03-28	International Minerals & Chemical Corp.	Stabilization of growth hormones
DE3801179A1 (de) *	1988-01-18	1989-07-27	Hoechst Ag	Stabilisierung von cephalosporinderivaten durch trocknung mit einem stabilisator sowie stabile zubereitungsformen mit cephalosporinderivaten
US6815435B2 (en) *	2000-07-13	2004-11-09	Daiichi Pharmaceutical Co., Ltd.	Pharmaceutical compositions containing DDS compounds
US7378408B2 (en) *	2001-11-30	2008-05-27	Pfizer Inc.	Methods of treatment and formulations of cephalosporin
NZ700372A (en)	2013-03-15	2016-01-29	Merck Sharp & Dohme	Ceftolozane antibiotic compositions
US9872906B2 (en)	2013-03-15	2018-01-23	Merck Sharp & Dohme Corp.	Ceftolozane antibiotic compositions
US20140274990A1 (en)	2013-03-15	2014-09-18	Cubist Pharmaceuticals, Inc.	Ceftolozane pharmaceutical compositions
US10376496B2 (en)	2013-09-09	2019-08-13	Merck, Sharp & Dohme Corp.	Treating infections with ceftolozane/tazobactam in subjects having impaired renal function
US20150094293A1 (en)	2013-09-27	2015-04-02	Calixa Therapeutics, Inc.	Solid forms of ceftolozane

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS532931B2 (nl) *	1973-12-05	1978-02-01
US3928592A (en) *	1974-02-22	1975-12-23	Lilly Co Eli	Antibiotic pharmaceutical compositions
US3993753A (en) *	1974-08-26	1976-11-23	American Home Products Corporation	Anhydrous ampicillin stabilization and resultant compositions
GB1463563A (en) *	1974-10-10	1977-02-02	Beecham Group Ltd	Pharmaceutical compositions
JPS5151511A (en) *	1974-10-25	1976-05-07	Tooru Tatsuhara	Aminosanseizai no anteikaho
US4180571A (en) *	1976-03-25	1979-12-25	Shionogi & Co., Ltd.	Arylmalonamido-1-oxadethiacephalosporins
JPS532931A (en) *	1976-06-30	1978-01-12	Saraya Kk	Toilet bowl cleaning method
FI773796A (fi) *	1976-12-17	1978-06-18	Leitzinger Oy	Foerfarande foer framstaellning av antibiotisk blandning
JPS53104722A (en) *	1977-02-19	1978-09-12	Tsumura Juntendo Kk	Production of powder for making herb medicine liquid agent
CA1127450A (en) *	1978-08-26	1982-07-13	Gordon L. Mcglennon	Load multiplying mechanisms
US4259485A (en) *	1979-04-24	1981-03-31	Eli Lilly And Company	Crystallization process

1980
- 1980-06-23 JP JP8578980A patent/JPS5711909A/ja active Granted
1981
- 1981-06-12 US US06/272,895 patent/US4418058A/en not_active Expired - Lifetime
- 1981-06-15 NZ NZ197414A patent/NZ197414A/en unknown
- 1981-06-17 IE IE1347/81A patent/IE51331B1/en not_active IP Right Cessation
- 1981-06-17 GB GB8118684A patent/GB2078737B/en not_active Expired
- 1981-06-18 NL NL8102943A patent/NL191777C/nl not_active IP Right Cessation
- 1981-06-19 FR FR8112087A patent/FR2484835A1/fr active Granted
- 1981-06-19 NO NO812090A patent/NO156036C/no not_active IP Right Cessation
- 1981-06-21 IL IL63136A patent/IL63136A/xx not_active IP Right Cessation
- 1981-06-22 ES ES503283A patent/ES8203887A1/es not_active Expired
- 1981-06-22 RO RO104646A patent/RO82720B/ro unknown
- 1981-06-22 ZA ZA814203A patent/ZA814203B/xx unknown
- 1981-06-22 KR KR1019810002265A patent/KR840000693B1/ko active
- 1981-06-22 PT PT73239A patent/PT73239B/pt unknown
- 1981-06-22 DK DK274981A patent/DK158443C/da not_active IP Right Cessation
- 1981-06-22 FI FI811948A patent/FI75490C/fi not_active IP Right Cessation
- 1981-06-22 SE SE8103904A patent/SE460702B/sv not_active IP Right Cessation
- 1981-06-22 IT IT67863/81A patent/IT1144812B/it active
- 1981-06-23 CH CH4151/81A patent/CH648210A5/de not_active IP Right Cessation
- 1981-06-23 BG BG052598A patent/BG37991A3/xx unknown
- 1981-06-23 HU HU811843A patent/HU183494B/hu unknown
- 1981-06-23 GR GR65316A patent/GR75646B/el unknown
- 1981-06-23 AT AT0278881A patent/AT380790B/de not_active IP Right Cessation
- 1981-06-23 BE BE0/205190A patent/BE889351A/fr not_active IP Right Cessation
- 1981-06-23 DE DE19813124592 patent/DE3124592A1/de active Granted
- 1981-06-23 AU AU72097/81A patent/AU541627B2/en not_active Expired
- 1981-06-23 YU YU1573/81A patent/YU44416B/xx unknown
- 1981-06-23 AR AR285821A patent/AR230007A1/es active
- 1981-06-23 CS CS814743A patent/CS221835B2/cs unknown
- 1981-06-23 CA CA000380462A patent/CA1164801A/en not_active Expired
- 1981-06-23 DD DD81231057A patent/DD159879A5/de unknown

Also Published As

Publication number	Publication date
BE889351A (fr)	1981-10-16
SE8103904L (sv)	1981-12-24
NO156036B (no)	1987-04-06
IE51331B1 (en)	1986-12-10
DK158443B (da)	1990-05-21
IT8167863A0 (it)	1981-06-22
FR2484835B1 (nl)	1983-07-01
BG37991A3 (en)	1985-09-16
CA1164801A (en)	1984-04-03
AR230007A1 (es)	1984-02-29
PT73239A (en)	1981-07-01
FI75490B (fi)	1988-03-31
JPS6364405B2 (nl)	1988-12-12
DE3124592A1 (de)	1982-02-11
DD159879A5 (de)	1983-04-13
DK274981A (da)	1981-12-24
KR830005848A (ko)	1983-09-14
CH648210A5 (de)	1985-03-15
GR75646B (nl)	1984-08-02
PT73239B (en)	1982-07-22
GB2078737A (en)	1982-01-13
CS221835B2 (en)	1983-04-29
IL63136A (en)	1984-07-31
FR2484835A1 (fr)	1981-12-24
NL8102943A (nl)	1982-01-18
YU157381A (en)	1984-10-31
SE460702B (sv)	1989-11-13
ES503283A0 (es)	1982-04-01
NZ197414A (en)	1984-10-19
NO812090L (no)	1981-12-28
HU183494B (en)	1984-05-28
RO82720A (ro)	1984-05-23
RO82720B (ro)	1984-07-30
ATA278881A (de)	1985-12-15
ES8203887A1 (es)	1982-04-01
GB2078737B (en)	1984-03-14
IL63136A0 (en)	1981-09-13
KR840000693B1 (ko)	1984-05-21
FI811948L (fi)	1981-12-24
NO156036C (no)	1987-07-15
FI75490C (fi)	1988-07-11
US4418058A (en)	1983-11-29
AT380790B (de)	1986-07-10
YU44416B (en)	1990-08-31
NL191777B (nl)	1996-04-01
AU541627B2 (en)	1985-01-17
ZA814203B (en)	1982-09-29
AU7209781A (en)	1983-01-06
DE3124592C2 (nl)	1990-12-20
JPS5711909A (en)	1982-01-21
IT1144812B (it)	1986-10-29
NL191777C (nl)	1996-08-02
IE811347L (en)	1981-12-23

Publication	Publication Date	Title
DK163243C (da)	1992-06-29	Fremgangsmaade til fremstilling af cephalosporinderivater
DK534481A (da)	1982-06-06	Fremgangsmaade til fremstilling af 1-sulfo-2-oxoazetidinderivater
DK2281A (da)	1981-07-08	Fremgangsmaade til fremstilling af tiazolinderivater
DK300981A (da)	1982-02-22	Fremgangsmaade til fremstilling af imidazolderivater
DK417981A (da)	1982-03-23	Fremgangsmaade til fremstilling af 3-aryl-5-isothiazol-derivater
DK161581A (da)	1981-12-07	Fremgangsmaade til fremstilling af imidazolderivater
DK88081A (da)	1981-08-30	Fremgangsmaade til fremstilling af tetrazolderivater
DK95383D0 (da)	1983-02-25	Fremgangsmade til fremstilling af cephalosporinderivater
DK319281A (da)	1982-01-18	Femgangsmaade til fremstilling af benzisoselenazoloner
DK57480A (da)	1981-08-12	Fremgangsmaade til fremstilling af insulinderivater
DK100281A (da)	1981-09-09	Fremgangsmaade til fremstilling af imidazolderivater
DK158443C (da)	1990-10-08	Fremgangsmaade til stabilisering af et lyophiliseret praeparat indeholdende et alkalimetalsalt af en 7beta-(alfa-carboxy-alfa-arylacetamido)-7alfa-methoxy-3-heterocyklisk thiomethyl-1-dethia-1-oxa-3-cephem-4-carboxylsyre
DK86283D0 (da)	1983-02-24	Fremgangsmade til fremstilling af cephalosporinderivater
DK564781A (da)	1982-06-27	Fremgangsmaade til fremstilling af pyrazoloindazolderivater
DK172181A (da)	1981-10-18	Fremgangsmaade til fremstilling af 9-carbamoyl-9-aminoalkylfluoren-derivater
DK554581A (da)	1982-06-16	Fremgangsmaade til fremstilling af alkylendioxybenzenderivater
DK565281A (da)	1982-06-20	Fremgangsmaade til fremstilling af quinolon-derivater
DK508881A (da)	1982-05-23	Fremgangsmaade til fremstilling af oploesninger af 7-amincophelosporansyrer
DK448981A (da)	1982-04-12	Fremgangsmaade til fremstilling af 4-chinolinmethanderivater
DK424781A (da)	1982-03-27	Fremgangsmaade til fremstilling af quinolonderivater
DK85281A (da)	1981-08-26	Fremgangsmaade til fremstilling af phenoxyderivater
DK142381A (da)	1981-10-03	Fremgangsmaade til fremstilling af substituerede triarylthiazolforbindelser
DK551481A (da)	1982-06-14	Fremgangsmaade til fremstilling af triazolderivater
DK156168C (da)	1989-12-04	Fremgangsmaade til fremstilling af en vandig oploesning af calciumnitrit
DK133081A (da)	1981-09-26	Fremgangsmaade til fremstilling af cephalosporinderivater

Legal Events

Date	Code	Title	Description
2001-07-09	PUP	Patent expired