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DK1557415T3 - Heterocykliske forbindelser og antitumorlægemidler indeholdende samme som den aktive ingrediens - Google Patents

Heterocykliske forbindelser og antitumorlægemidler indeholdende samme som den aktive ingrediens

Info

Publication number
DK1557415T3
DK1557415T3 DK03758850.6T DK03758850T DK1557415T3 DK 1557415 T3 DK1557415 T3 DK 1557415T3 DK 03758850 T DK03758850 T DK 03758850T DK 1557415 T3 DK1557415 T3 DK 1557415T3
Authority
DK
Denmark
Prior art keywords
same
active ingredient
heterocyclic compounds
antitumor drugs
drugs containing
Prior art date
Application number
DK03758850.6T
Other languages
English (en)
Inventor
Seiichiro Kawashima
Toshiyuki Matsuno
Shinichi Yaguchi
Yoshio Tsuchida
Hiroya Sasahara
Tetsuo Watanabe
Kenichi Saitoh
Original Assignee
Zenyaku Kogyo Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zenyaku Kogyo Kk filed Critical Zenyaku Kogyo Kk
Application granted granted Critical
Publication of DK1557415T3 publication Critical patent/DK1557415T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK03758850.6T 2002-10-25 2003-10-24 Heterocykliske forbindelser og antitumorlægemidler indeholdende samme som den aktive ingrediens DK1557415T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2002311086 2002-10-25
PCT/JP2003/013589 WO2004037812A1 (ja) 2002-10-25 2003-10-24 複素環式化合物及びそれを有効成分とする抗腫瘍剤

Publications (1)

Publication Number Publication Date
DK1557415T3 true DK1557415T3 (da) 2012-09-17

Family

ID=32171070

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03758850.6T DK1557415T3 (da) 2002-10-25 2003-10-24 Heterocykliske forbindelser og antitumorlægemidler indeholdende samme som den aktive ingrediens

Country Status (11)

Country Link
US (1) US7153853B2 (da)
EP (1) EP1557415B1 (da)
JP (1) JP4493503B2 (da)
KR (1) KR101046015B1 (da)
CN (1) CN100402523C (da)
AU (1) AU2003275630B2 (da)
CA (1) CA2503451C (da)
DK (1) DK1557415T3 (da)
ES (1) ES2389253T3 (da)
HK (1) HK1086830A1 (da)
WO (1) WO2004037812A1 (da)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2280530T3 (es) * 2001-04-27 2007-09-16 Zenyaku Kogyo Kabushiki Kaisha Compuesto heterociclico y agente antitumoral que contiene el mismo como principio activo.
ES2389253T3 (es) 2002-10-25 2012-10-24 Zenyaku Kogyo Kabushiki Kaisha Compuestos heterocíclicos y agentes antitumorales que comprenden los mismos como ingrediente activo
ES2400056T3 (es) * 2004-03-31 2013-04-05 Zenyaku Kogyo Kabushikikaisha Compuesto heterocíclico y agente anti tumores malignos que comprende el mismo como componente eficaz
GB0415364D0 (en) * 2004-07-09 2004-08-11 Astrazeneca Ab Pyrimidine derivatives
JP5089377B2 (ja) * 2005-03-11 2012-12-05 全薬工業株式会社 複素環式化合物を有効成分とする免疫抑制剤及び抗腫瘍剤
US20070244110A1 (en) * 2006-04-14 2007-10-18 Zenyaku Kogyo Kabushiki Kaisha Treatment of prostate cancer, melanoma or hepatic cancer
US20080065746A1 (en) * 2006-09-07 2008-03-13 Ace*Comm Corporation Consumer configurable mobile communication web filtering solution
WO2008032033A1 (en) * 2006-09-14 2008-03-20 Astrazeneca Ab 4-benzimidazolyl-2-morpholino-6-piperazinylpyrimidine derivatives as pi3k and mtor inhibitors for the treatment of proliferative disorders
WO2008032027A1 (en) * 2006-09-14 2008-03-20 Astrazeneca Ab Pyrimidine derivatives
WO2008032077A1 (en) * 2006-09-14 2008-03-20 Astrazeneca Ab Pyrimidine derivatives
WO2008032064A1 (en) * 2006-09-14 2008-03-20 Astrazeneca Ab Pyrimidine derivatives
CN101563339A (zh) * 2006-09-14 2009-10-21 阿斯利康(瑞典)有限公司 作为 p i 3 k和 m t o r抑制剂用于治疗增殖性疾病的 2 -苯并咪唑基 - 6 -吗啉代 - 4 - (氮杂环丁烷、吡咯烷、哌啶或氮杂)嘧啶衍生物
WO2008032060A1 (en) * 2006-09-14 2008-03-20 Astrazeneca Ab 4-benzimidaz0lyl-6-m0rph0lin0-2-piperazinylpyrimidine derivatives as p13k and mtor inhibitors for the treatment of proliferative disorders
JP2010503651A (ja) * 2006-09-14 2010-02-04 アストラゼネカ アクチボラグ 増殖性障害の治療用のＰＩ３Ｋ及びｍＴＯＲ阻害剤としての２−ベンゾイミダゾリル−６−モルホリノ−フェニルピリミジン誘導体
PT2409975E (pt) * 2007-11-22 2015-07-27 Zenyaku Kogyo Kk Dispersões sólidas compreendendo um corpo amorfo composto por um composto antitumoral heterocíclico
WO2009120094A2 (en) * 2008-03-27 2009-10-01 Auckland Uniservices Limited Substituted pyrimidines and triazines and their use in cancer therapy
TWI378933B (en) * 2008-10-14 2012-12-11 Daiichi Sankyo Co Ltd Morpholinopurine derivatives
HUP0800768A2 (en) 2008-12-18 2012-08-28 Bioblocks Magyarorszag Gyogyszerkemiai Es Fejlesztoe Kft 1,3-heterocycles condensed with monoterpene skeleton, their use and pharmaceutical compositions comprising such compounds
KR20110120286A (ko) 2009-02-12 2011-11-03 아스텔라스세이야쿠 가부시키가이샤 헤테로환 유도체
CA2756067A1 (en) 2009-03-27 2010-09-30 Pathway Therapeutics, Inc. Pyrimidinyl and 1,3,5-triazinyl benzimidazole sulfonamides and their use in cancer therapy
WO2010110686A1 (en) 2009-03-27 2010-09-30 Pathway Therapeutics Limited Pyrimidinyl and 1,3,5 triazinyl benzimidazoles and their use in cancer therapy
WO2011005119A1 (en) 2009-07-07 2011-01-13 Pathway Therapeutics Limited Pyrimidinyl and 1,3,5-triazinyl benzimidazoles and their use in cancer therapy
WO2012020762A1 (ja) * 2010-08-10 2012-02-16 アステラス製薬株式会社 へテロ環化合物
CA2831582C (en) 2011-03-28 2019-01-08 Mei Pharma, Inc. (alpha-substituted aralkylamino and heteroarylalkylamino) pyrimidinyl and 1,3,5-triazinyl benzimidazoles, pharmaceutical compositions thereof, and their use in treating proliferative diseases
WO2018131659A1 (ja) * 2017-01-11 2018-07-19 国立研究開発法人国立がん研究センター 免疫療法剤
KR20240097982A (ko) 2017-05-23 2024-06-27 메이 파마, 아이엔씨. 병용 요법
CN111212643A (zh) 2017-08-14 2020-05-29 梅制药公司 联合疗法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5489591A (en) * 1992-02-28 1996-02-06 Zenyaku Kogyo Kabushiki Kaisha S-triazine derivative and remedy for estrogen-dependent disease containing said derivative as effective component
CA2297326C (en) * 1997-07-24 2007-03-20 Zenyaku Kogyo Kabushiki Kaisha Heterocyclic compound and antitumor agent containing the same as active component
AU3078000A (en) * 1999-01-25 2000-08-07 Zenyaku Kogyo Kabushiki Kaisha Heterocyclic compounds and antitumor agents containing the same as the active ingredient
ES2280530T3 (es) * 2001-04-27 2007-09-16 Zenyaku Kogyo Kabushiki Kaisha Compuesto heterociclico y agente antitumoral que contiene el mismo como principio activo.
ES2389253T3 (es) 2002-10-25 2012-10-24 Zenyaku Kogyo Kabushiki Kaisha Compuestos heterocíclicos y agentes antitumorales que comprenden los mismos como ingrediente activo

Also Published As

Publication number Publication date
HK1086830A1 (en) 2006-09-29
AU2003275630B2 (en) 2010-02-18
JP4493503B2 (ja) 2010-06-30
KR101046015B1 (ko) 2011-07-01
EP1557415B1 (en) 2012-06-06
CN100402523C (zh) 2008-07-16
CA2503451A1 (en) 2004-05-06
US20060009440A1 (en) 2006-01-12
EP1557415A1 (en) 2005-07-27
JPWO2004037812A1 (ja) 2006-02-23
ES2389253T3 (es) 2012-10-24
CA2503451C (en) 2011-07-12
EP1557415A4 (en) 2011-02-23
KR20050056267A (ko) 2005-06-14
US7153853B2 (en) 2006-12-26
AU2003275630A1 (en) 2004-05-13
CN1708495A (zh) 2005-12-14
WO2004037812A1 (ja) 2004-05-06

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