DK1499872T3 - Automatiseret apparat til molekylær patologi med faste glideplatforme - Google Patents
Automatiseret apparat til molekylær patologi med faste glideplatforme Download PDFInfo
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- DK1499872T3 DK1499872T3 DK03726474.4T DK03726474T DK1499872T3 DK 1499872 T3 DK1499872 T3 DK 1499872T3 DK 03726474 T DK03726474 T DK 03726474T DK 1499872 T3 DK1499872 T3 DK 1499872T3
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- reagent
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- slide
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Links
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
- G01N1/312—Apparatus therefor for samples mounted on planar substrates
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
- Y10T436/111666—Utilizing a centrifuge or compartmented rotor
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
- Y10T436/112499—Automated chemical analysis with sample on test slide
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
- Y10T436/115831—Condition or time responsive
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/2575—Volumetric liquid transfer
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Sampling And Sample Adjustment (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Claims (4)
1. Automatisk forarbejdningsapparat til objektbærer omfattende: (a) en objektbærerholder (33); (b) en reagensholder (300); (c) en dyseholder (100); og (d) en reagensdispenser, kendetegnet ved at objektbærerholderen (33) og reagensholderen (300) er operativt fast anbragt, og dyseholderen (100) er selektivt roterbart bevægelig i forhold til objektbærerholderen (33) og reagensholderen (300), hvor reagensholderen (300), dyseholderen (100) og reagensdispenseren alle er monteret vertikalt over objektbærerholderen (33).
2. Apparat ifølge krav 1, kendetegnet ved et eller flere af følgende træk: (a) hvor objektbærerholderen (33) bærer en flerhed af adskilte objektbærerplatforme (50); (b) hvor objektbærerholderen (33) bærer platforme der omfatter varmelegemer og/eller temperaturfølere; (c) hvor objektbærerholderen (33) omfatter mindst et væskeafløb (38); (d) hvor objektbærerholderen (33) er forskydeligt monteret i apparatet for at tillade isætning og aftagning af objektbærere i objektbærerholderen (33); (e) hvor objektbærerholderen (33) er forskydeligt monteret på skinner (40); (f) hvor objektbærerholderen (33) er forskydeligt monteret på skinner (40), og omfatter en dæmper til blød dæmpning af skinnernes (40) bevægelse. (g) hvor objektbærerholderen (33) er vertikalt justerbart støttet på en løftemekanisme; (h) hvor reagensdispenseren er selektivt bevægelig i forhold til reagensholderen (300); (i) hvor reagensdispenseren omfatter mindst en robotiseret dispenseringspipette; (j) hvor reagensdispenseren omfatter mindst en robotiseret dispenseringspipette der er vertikalt bevægelig mellem en driftsposition og en transportposition; (k) hvor reagensdispenseren omfatter to adskilte robotiserede dispenseringspipetter; (l) hvor dyseholderen (100) bærer mindst en vortex luftstråle eller stråleudløb; (m) hvor dyseholderen (100) bærer mindst en applikator til påføring af dækfluid til objektbæreren; (n) hvor dyseholderen (100) er roterbart bevægelig plus eller minus omtrent 180 ° fra sin udgangsstilling; (o) hvor reagensdispenseren er roterbart bevægelig plus eller minus omtrent 185 ° fra sin udgangsstilling; (p) yderligere omfattende en stregkodelæser (406) til objektbærere båret på dyseholderen (100) og/eller båret med reagensdispenseren; (q) yderligere omfattende en processor til at styre bevægelse af dyseholderen og reagensdispenseren; (r) yderligere omfattende en dispenservaskestation (121, 122) monteret på dyseholderen (100); (s) omfattende to dispenservaskestationer (121, 122) monteret i afstand fra hinanden på dyseholderen (100); og (t) hvor objektbærerholderne er fast positioneret i forhold til reagensdispenseren.
3. Fremgangsmåde til forarbejdning af en flerhed af objektbærere hver med en biologisk prøve derpå, hvor objektbærerne er fast positioneret og reagenser er tilvejebragt monteret til en operativt fastholdt reagensbærer monteret vertikalt over objektbærerne, med trinnene at: (a) forberede en første objektbærer (60) til biologisk behandling med et reagens; (b) bevæge en reagensdispenser til en valgt reagensbeholder (302); (c) trække et forvalgt volumen reagens fra reagensbeholderen (302) ind i reagensdispenseren; (d) bevæge reagensdispenseren til den første objektbærer; (e) dispensere det forvalgte volumen reagens fra reagensdispenseren på den første objektbærer; (f) forberede en anden objektbærer til behandling med et reagens; (g) rengøre reagensdispenseren; (h) bevæge reagensdispenseren til et valgt reagens der kan være det samme eller forskelligt fra reagenset ifølge trin (b); (i) trække en forvalgt mængde reagens fra reagensbeholderen (302) valgt i trin (h) ind i reagensdispenseren; (j) bevæge reagensdispenseren til den andet objektbærer; (k) dispensere det forvalgte volumen reagens valgt i trin (h) fra reagensdispenseren på den andet objektbærer; (l) rengøre reagensdispenseren; og (m) gentage trinnene (h) - (I).
4. Fremgangsmåden ifølge krav 3, kendetegnet ved et eller begge af følgende træk: (a) hvor to reagensdispensere (302) er tilvejebragt og omfattende trinnet at rengøre en af reagensdispenserne mens den anden reagensdispenser anvendes til at trække og udlevere reagens på en valgt objektbærer; og (b) hvor reagensdispenseren omfatter en robotiseret sprøjte, og reagens optages ved aspiration.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37567902P | 2002-04-26 | 2002-04-26 | |
| PCT/US2003/012947 WO2003091710A1 (en) | 2002-04-26 | 2003-04-28 | Automated molecular pathology apparatus having fixed slide platforms |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1499872T3 true DK1499872T3 (da) | 2015-12-14 |
Family
ID=29270685
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK03726474.4T DK1499872T3 (da) | 2002-04-26 | 2003-04-28 | Automatiseret apparat til molekylær patologi med faste glideplatforme |
| DK11002712.5T DK2420814T3 (da) | 2002-04-26 | 2003-04-28 | Automatisk objektglasbearbejdningsapparat |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK11002712.5T DK2420814T3 (da) | 2002-04-26 | 2003-04-28 | Automatisk objektglasbearbejdningsapparat |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US7378055B2 (da) |
| EP (2) | EP2420814B1 (da) |
| JP (1) | JP4091599B2 (da) |
| CN (1) | CN1650159A (da) |
| AU (1) | AU2003228709B2 (da) |
| CA (1) | CA2482763C (da) |
| DK (2) | DK1499872T3 (da) |
| ES (2) | ES2556242T3 (da) |
| WO (1) | WO2003091710A1 (da) |
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| US7951612B2 (en) * | 1999-07-08 | 2011-05-31 | Lee H. Angros | In situ heat induced antigen recovery and staining apparatus and method |
| US7897106B2 (en) * | 1999-07-08 | 2011-03-01 | Lee Angros | Situ heat induced antigen recovery and staining apparatus and method |
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2003
- 2003-04-28 DK DK03726474.4T patent/DK1499872T3/da active
- 2003-04-28 EP EP11002712.5A patent/EP2420814B1/en not_active Expired - Lifetime
- 2003-04-28 AU AU2003228709A patent/AU2003228709B2/en not_active Expired
- 2003-04-28 CA CA002482763A patent/CA2482763C/en not_active Expired - Lifetime
- 2003-04-28 DK DK11002712.5T patent/DK2420814T3/da active
- 2003-04-28 ES ES03726474.4T patent/ES2556242T3/es not_active Expired - Lifetime
- 2003-04-28 JP JP2004500049A patent/JP4091599B2/ja not_active Expired - Lifetime
- 2003-04-28 ES ES11002712.5T patent/ES2548158T3/es not_active Expired - Lifetime
- 2003-04-28 US US10/424,372 patent/US7378055B2/en not_active Expired - Lifetime
- 2003-04-28 CN CNA038092328A patent/CN1650159A/zh active Pending
- 2003-04-28 WO PCT/US2003/012947 patent/WO2003091710A1/en active Application Filing
- 2003-04-28 EP EP03726474.4A patent/EP1499872B1/en not_active Expired - Lifetime
-
2006
- 2006-11-09 US US11/558,257 patent/US20070086917A1/en not_active Abandoned
-
2010
- 2010-06-18 US US12/818,369 patent/US7935534B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP1499872A4 (en) | 2007-06-20 |
| EP2420814A3 (en) | 2013-09-04 |
| CA2482763A1 (en) | 2003-11-06 |
| CN1650159A (zh) | 2005-08-03 |
| AU2003228709B2 (en) | 2006-12-21 |
| US7935534B2 (en) | 2011-05-03 |
| EP1499872A1 (en) | 2005-01-26 |
| CA2482763C (en) | 2008-07-29 |
| EP2420814A2 (en) | 2012-02-22 |
| US20070086917A1 (en) | 2007-04-19 |
| EP1499872B1 (en) | 2015-11-18 |
| AU2003228709A1 (en) | 2003-11-10 |
| JP2005524068A (ja) | 2005-08-11 |
| WO2003091710A1 (en) | 2003-11-06 |
| US7378055B2 (en) | 2008-05-27 |
| ES2556242T3 (es) | 2016-01-14 |
| EP2420814B1 (en) | 2015-08-26 |
| JP4091599B2 (ja) | 2008-05-28 |
| US20100255532A1 (en) | 2010-10-07 |
| US20030203493A1 (en) | 2003-10-30 |
| DK2420814T3 (da) | 2015-10-05 |
| ES2548158T3 (es) | 2015-10-14 |
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