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DK149954C - Analogifremgangsmaade til fremstilling af 18-umaettede prostacyklinderivater - Google Patents

Analogifremgangsmaade til fremstilling af 18-umaettede prostacyklinderivater

Info

Publication number
DK149954C
DK149954C DK336878A DK336878A DK149954C DK 149954 C DK149954 C DK 149954C DK 336878 A DK336878 A DK 336878A DK 336878 A DK336878 A DK 336878A DK 149954 C DK149954 C DK 149954C
Authority
DK
Denmark
Prior art keywords
saturated
preparation
analogy procedure
prostacycline
derivatives
Prior art date
Application number
DK336878A
Other languages
Danish (da)
English (en)
Other versions
DK336878A (da
DK149954B (da
Inventor
Werner Skuballa
Bernd Raduechel
Norbert Schwarz
Helmut Vorbrueggen
Bernd Mueller
Gerda Mannesmann
Olaf Loge
Ekkehardt Schillinger
Jorge Casals-Stenzel
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of DK336878A publication Critical patent/DK336878A/da
Publication of DK149954B publication Critical patent/DK149954B/da
Application granted granted Critical
Publication of DK149954C publication Critical patent/DK149954C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
DK336878A 1977-07-29 1978-07-28 Analogifremgangsmaade til fremstilling af 18-umaettede prostacyklinderivater DK149954C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19772734791 DE2734791A1 (de) 1977-07-29 1977-07-29 Neue prostaglandin-i tief 2 -derivate und verfahren zu ihrer herstellung
DE2734791 1977-07-29

Publications (3)

Publication Number Publication Date
DK336878A DK336878A (da) 1979-01-30
DK149954B DK149954B (da) 1986-11-03
DK149954C true DK149954C (da) 1987-06-15

Family

ID=6015442

Family Applications (1)

Application Number Title Priority Date Filing Date
DK336878A DK149954C (da) 1977-07-29 1978-07-28 Analogifremgangsmaade til fremstilling af 18-umaettede prostacyklinderivater

Country Status (26)

Country Link
US (1) US4191694A (xx)
JP (1) JPS5427556A (xx)
AT (1) AT371454B (xx)
AU (1) AU523593B2 (xx)
BE (1) BE869372A (xx)
CA (1) CA1180700A (xx)
CH (1) CH636354A5 (xx)
CS (1) CS207640B2 (xx)
DD (1) DD138904A5 (xx)
DE (1) DE2734791A1 (xx)
DK (1) DK149954C (xx)
ES (1) ES472099A1 (xx)
FR (1) FR2398741A1 (xx)
GB (1) GB2001650B (xx)
GR (1) GR72256B (xx)
HU (1) HU179346B (xx)
IE (1) IE47304B1 (xx)
IL (1) IL55236A (xx)
IT (1) IT1097554B (xx)
LU (1) LU80043A1 (xx)
NL (1) NL7806861A (xx)
NZ (1) NZ187849A (xx)
SE (1) SE443978B (xx)
SU (1) SU921465A3 (xx)
YU (1) YU41595B (xx)
ZA (1) ZA784307B (xx)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4264523A (en) * 1979-04-02 1981-04-28 The Upjohn Company 19,20-Didehydro-13,14-dihydro-PG1 amides
US4283350A (en) * 1979-04-02 1981-08-11 The Upjohn Company 19,20-Didehydro-PG2 amides
US4264524A (en) * 1979-04-02 1981-04-28 The Upjohn Company 19,20-Didehydro-PG1 amides
US4278815A (en) * 1979-04-02 1981-07-14 The Upjohn Company 19-Keto-PG amides
US4276436A (en) * 1979-04-02 1981-06-30 The Upjohn Company 19-Keto-PG sulfonylamides
US4281191A (en) * 1979-04-02 1981-07-28 The Upjohn Company 19-Hydroxy-19-methyl-PG amides
US4283351A (en) * 1979-04-02 1981-08-11 The Upjohn Company 19,20-Didehydro-13,14-dihydro-PG2 amides
US4281150A (en) * 1979-07-05 1981-07-28 The Upjohn Company 19-Hydroxy-19-methyl-6a-carba-PGI2 sulfonylamides
US4267352A (en) * 1979-07-05 1981-05-12 The Upjohn Company 19-Hydroxy-19-methyl-6-oxo-PGF1 sulfonylamides
US4312997A (en) * 1979-07-05 1982-01-26 The Upjohn Company 19-Hydroxy-6-oxo-PGF1 amides
US4267371A (en) * 1979-07-05 1981-05-12 The Upjohn Company 19-Hydroxy-6a-carba-PGI2 amides
US4289904A (en) * 1979-07-05 1981-09-15 The Upjohn Company 19-Hydroxy-6a-carba-PGI2 sulfonylamides
JPS6033429B2 (ja) * 1980-04-28 1985-08-02 小野薬品工業株式会社 プロスタグランジン類似化合物
DE3041602A1 (de) * 1980-10-31 1982-06-16 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue 5-cyan-prostacyclinderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3107100A1 (de) * 1981-02-20 1982-09-09 Schering Ag, 1000 Berlin Und 4619 Bergkamen Azaprostacycline, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung
JPS58124778A (ja) * 1982-01-20 1983-07-25 Toray Ind Inc 5,6,7−トリノル−4,8−インタ−m−フエニレンPGI↓2誘導体
US4539433A (en) * 1982-11-24 1985-09-03 Tdk Corporation Electromagnetic shield
JPH0284398U (xx) * 1988-12-20 1990-06-29
JPH0397493U (xx) * 1990-01-23 1991-10-07
JPH0726876Y2 (ja) * 1990-07-02 1995-06-14 日立フェライト株式会社 電波暗室用電波吸収体
KR930011548B1 (ko) * 1991-08-13 1993-12-10 한국과학기술연구원 적층형 전파흡수체
JP3340732B1 (ja) * 2001-10-05 2002-11-05 日本医薬品工業株式会社 シクロペンタベンゾフラン誘導体の製造方法及びその製造原料となる新規化合物

Also Published As

Publication number Publication date
FR2398741B1 (xx) 1980-10-31
IL55236A0 (en) 1978-09-29
GR72256B (xx) 1983-10-06
DE2734791A1 (de) 1979-02-15
GB2001650A (en) 1979-02-07
GB2001650B (en) 1982-03-03
DD138904A5 (de) 1979-11-28
DK336878A (da) 1979-01-30
SU921465A3 (ru) 1982-04-15
NL7806861A (nl) 1979-01-31
CH636354A5 (de) 1983-05-31
IT7826113A0 (it) 1978-07-26
JPS5427556A (en) 1979-03-01
IE47304B1 (en) 1984-02-22
IT1097554B (it) 1985-08-31
ATA551578A (de) 1982-11-15
YU41595B (en) 1987-10-31
IE781538L (en) 1979-01-29
DE2734791C2 (xx) 1990-09-06
AT371454B (de) 1983-06-27
LU80043A1 (xx) 1978-12-12
US4191694A (en) 1980-03-04
ZA784307B (en) 1979-07-25
BE869372A (fr) 1979-01-29
AU523593B2 (en) 1982-08-05
JPS6259700B2 (xx) 1987-12-12
CA1180700A (en) 1985-01-08
SE443978B (sv) 1986-03-17
AU3843978A (en) 1980-01-31
FR2398741A1 (fr) 1979-02-23
HU179346B (en) 1982-10-28
ES472099A1 (es) 1979-03-16
NZ187849A (en) 1981-01-23
SE7808184L (sv) 1979-01-30
DK149954B (da) 1986-11-03
YU176278A (en) 1983-01-21
CS207640B2 (en) 1981-08-31
IL55236A (en) 1982-09-30

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