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DK1451302T3 - In vitro rekonstituerede lag af humant hornhindeepitel samt fremgangsmåde til fremstilling deraf - Google Patents

In vitro rekonstituerede lag af humant hornhindeepitel samt fremgangsmåde til fremstilling deraf

Info

Publication number
DK1451302T3
DK1451302T3 DK01274401T DK01274401T DK1451302T3 DK 1451302 T3 DK1451302 T3 DK 1451302T3 DK 01274401 T DK01274401 T DK 01274401T DK 01274401 T DK01274401 T DK 01274401T DK 1451302 T3 DK1451302 T3 DK 1451302T3
Authority
DK
Denmark
Prior art keywords
well
layers
preparation
corneal epithelium
human corneal
Prior art date
Application number
DK01274401T
Other languages
English (en)
Inventor
Luca Michele De
Graziella Pellegrini
Original Assignee
Idi Farmaceutici Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Idi Farmaceutici Spa filed Critical Idi Farmaceutici Spa
Application granted granted Critical
Publication of DK1451302T3 publication Critical patent/DK1451302T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0621—Eye cells, e.g. cornea, iris pigmented cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/56—Fibrin; Thrombin

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Prostheses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK01274401T 2001-08-03 2001-11-28 In vitro rekonstituerede lag af humant hornhindeepitel samt fremgangsmåde til fremstilling deraf DK1451302T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2001RM000476A ITRM20010476A1 (it) 2001-08-03 2001-08-03 Lamine di epitelio corneale umano ricostruite e metodo per il loro ottenimento.
PCT/IT2001/000603 WO2003012083A1 (en) 2001-08-03 2001-11-28 In vitro reconstituted sheets of human corneal epithelium and method of producing the same

Publications (1)

Publication Number Publication Date
DK1451302T3 true DK1451302T3 (da) 2008-09-08

Family

ID=11455714

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01274401T DK1451302T3 (da) 2001-08-03 2001-11-28 In vitro rekonstituerede lag af humant hornhindeepitel samt fremgangsmåde til fremstilling deraf

Country Status (12)

Country Link
US (1) US6610538B2 (da)
EP (1) EP1451302B1 (da)
AT (1) ATE397058T1 (da)
CY (1) CY1108257T1 (da)
DE (1) DE60134280D1 (da)
DK (1) DK1451302T3 (da)
ES (1) ES2307570T3 (da)
FR (1) FR15C0055I2 (da)
IT (1) ITRM20010476A1 (da)
NL (1) NL300754I2 (da)
PT (1) PT1451302E (da)
WO (1) WO2003012083A1 (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050186672A1 (en) * 2004-01-27 2005-08-25 Reliance Life Sciences Pvt. Ltd. Tissue system with undifferentiated stem cells derived from corneal limbus
US8187875B2 (en) * 2004-02-26 2012-05-29 Reliance Life Sciences Pvt. Ltd. Dopaminergic neurons derived from corneal limbus, methods of isolation and uses thereof
BRPI0506536C1 (pt) * 2004-02-26 2007-05-22 Reliance Life Sciences Pvt Ltd neurÈnios dopaminérgicos derivados do limbus corneal, métodos de isolamento e usos dos mesmos
US20060216821A1 (en) * 2004-02-26 2006-09-28 Reliance Life Sciences Pvt. Ltd. Pluripotent embryonic-like stem cells derived from corneal limbus, methods of isolation and uses thereof
ITRM20040273A1 (it) * 2004-06-03 2004-09-03 Farmigea Spa Metodo per l'isolamento e l'espansione ex vivo di cellule staminali corneali umane e loro relativi usi.
US8338175B2 (en) * 2006-02-24 2012-12-25 Reliance Life Sciences Pvt. Ltd. Conjunctival tissue system
WO2011040888A1 (en) * 2009-10-01 2011-04-07 Singapore Health Services Pte Ltd A biodegradable composition or combination and uses thereof
RU2505303C2 (ru) * 2011-09-13 2014-01-27 Общество с ограниченной ответственностью "Офтальмологические биотехнологии" Способ получения биотрансплантата для роговицы
FR2993282B1 (fr) 2012-07-13 2017-11-10 Expanscience Lab Procede d'identification de marqueurs moleculaires de la peau d'enfant
FR3011008B1 (fr) 2013-09-24 2017-12-29 Expanscience Lab Procedes d'evaluation des effets deleteres des uv sur la peau d'enfant
FR3016373B1 (fr) 2014-01-10 2018-01-19 Laboratoires Expanscience Modele de peau de mammelon reconstitue
FR3019186B1 (fr) 2014-03-31 2019-06-07 Laboratoires Expanscience Procedes d'evaluation des effets deleteres de l'urine sur la peau d'enfant
FR3045669B1 (fr) 2015-12-16 2019-04-05 Laboratoires Expanscience Procedes d'evaluation des effets de la deshydratation sur la peau d'enfant
FR3053053B1 (fr) 2016-06-23 2018-07-13 Laboratoires Expanscience Modeles de la dermatite atopique juvenile
FR3068045B1 (fr) 2017-06-22 2021-06-04 Expanscience Lab Modeles de peau sensible reconstituee
EP3867357B1 (en) * 2018-10-19 2024-09-25 Regents of the University of Minnesota Methods of isolating and using descemet's membrane and compositions including isolated descemet's membrane
FR3133198A1 (fr) 2022-03-04 2023-09-08 Pierre Fabre Dermo-Cosmetique Modele de peau reconstituee
FR3138149A1 (fr) 2022-07-25 2024-01-26 Pierre Fabre Dermo-Cosmetique Méthode d’évaluation in vitro de l’activité photoprotectrice d’un actif

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1255657B (it) 1992-05-29 1995-11-09 Colture di tessuto di mucosa congiuntivale differenziata, procedimentoper la loro preparazione e supporti per il loro uso.
US5827641A (en) 1992-11-13 1998-10-27 Parenteau; Nancy L. In vitro cornea equivalent model
CA2227827A1 (en) 1998-01-23 1999-07-23 Unknown In vitro artificial cornea and sclera

Also Published As

Publication number Publication date
EP1451302A1 (en) 2004-09-01
PT1451302E (pt) 2008-09-08
US6610538B2 (en) 2003-08-26
EP1451302B1 (en) 2008-05-28
WO2003012083A1 (en) 2003-02-13
DE60134280D1 (de) 2008-07-10
FR15C0055I2 (fr) 2016-06-24
CY1108257T1 (el) 2014-02-12
FR15C0055I1 (da) 2015-09-11
ITRM20010476A0 (it) 2001-08-03
NL300754I2 (da) 2016-09-01
ES2307570T3 (es) 2008-12-01
ATE397058T1 (de) 2008-06-15
US20030027333A1 (en) 2003-02-06
ITRM20010476A1 (it) 2003-02-03

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