DK1446010T3 - Stabiliseret azithromycin-sammensætning - Google Patents
Stabiliseret azithromycin-sammensætningInfo
- Publication number
- DK1446010T3 DK1446010T3 DK02801784T DK02801784T DK1446010T3 DK 1446010 T3 DK1446010 T3 DK 1446010T3 DK 02801784 T DK02801784 T DK 02801784T DK 02801784 T DK02801784 T DK 02801784T DK 1446010 T3 DK1446010 T3 DK 1446010T3
- Authority
- DK
- Denmark
- Prior art keywords
- azithromycin
- stabilized
- compositions
- stabilized azithromycin
- azithromycin composition
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33634601P | 2001-10-18 | 2001-10-18 | |
| US33193101P | 2001-11-21 | 2001-11-21 | |
| US34129501P | 2001-12-17 | 2001-12-17 | |
| PCT/US2002/033339 WO2003032922A2 (en) | 2001-10-18 | 2002-10-18 | Stabilized azithromycin compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1446010T3 true DK1446010T3 (da) | 2009-06-22 |
Family
ID=27406829
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK02801784T DK1446010T3 (da) | 2001-10-18 | 2002-10-18 | Stabiliseret azithromycin-sammensætning |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US6764997B2 (da) |
| EP (1) | EP1446010B1 (da) |
| AT (1) | ATE428403T1 (da) |
| AU (1) | AU2002335087A1 (da) |
| CA (1) | CA2463619C (da) |
| DE (1) | DE60232005D1 (da) |
| DK (1) | DK1446010T3 (da) |
| ES (1) | ES2324527T3 (da) |
| HK (1) | HK1067278A1 (da) |
| HU (1) | HUP0402291A2 (da) |
| IL (1) | IL161398A0 (da) |
| PT (1) | PT1446010E (da) |
| WO (1) | WO2003032922A2 (da) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6861413B2 (en) | 2001-05-22 | 2005-03-01 | Pfizer Inc. | Stable non-dihydrate azithromycin oral suspensions |
| JP2004530703A (ja) | 2001-05-22 | 2004-10-07 | ファイザー・プロダクツ・インク | 結晶形アジスロマイシン |
| US20080149521A9 (en) * | 2001-10-18 | 2008-06-26 | Michael Pesachovich | Methods of stabilizing azithromycin |
| PL371259A1 (en) * | 2001-12-21 | 2005-06-13 | Pfizer Products Inc. | Directly compressible formulations of azithromycin |
| WO2003053399A2 (en) * | 2001-12-21 | 2003-07-03 | Pfizer Products Inc. | Methods for wet granulating azithromycin |
| MXPA04007427A (es) * | 2002-02-01 | 2004-10-11 | Pfizer Prod Inc | Formulaciones de azitromicina granuladas por via seca. |
| CA2517004A1 (en) * | 2003-02-19 | 2004-09-02 | Teva Pharmaceutical Industries Ltd. | Methods of stabilizing azithromycin during storage by packaging in a gas impermeable container |
| WO2004087729A1 (en) * | 2003-03-25 | 2004-10-14 | Teva Pharmaceutical Industries Ltd. | Degradation products of azithromycin, and methods for their identification |
| BRPI0410638A (pt) * | 2003-04-17 | 2006-06-13 | Sandoz Ag | derivados de azitromicina |
| US20070185194A1 (en) * | 2003-07-01 | 2007-08-09 | Kamal Mehta | Stable oral compositions of azithromycin monohydrate |
| US20050013835A1 (en) * | 2003-07-15 | 2005-01-20 | Pfizer Inc. | Stable non-dihydrate azithromycin oral suspensions |
| AU2004275594A1 (en) * | 2003-09-30 | 2005-04-07 | Solubest Ltd. | Water soluble nanoparticles inclusion complexes |
| JP2007513147A (ja) | 2003-12-04 | 2007-05-24 | ファイザー・プロダクツ・インク | 押し出し機を使用して、好ましくはポロキサマーとグリセリドを含有する多粒子結晶性医薬組成物を製造するための噴霧凝結方法 |
| US20060116336A1 (en) * | 2004-03-17 | 2006-06-01 | American Pharmaceutical Partners, Inc. | Lyophilized azithromycin formulation |
| US7468428B2 (en) * | 2004-03-17 | 2008-12-23 | App Pharmaceuticals, Llc | Lyophilized azithromycin formulation |
| JP2008524318A (ja) * | 2004-12-21 | 2008-07-10 | ファイザー・プロダクツ・インク | 安定なアジスロマイシン非二水和物の経口用懸濁液剤 |
| US20060198895A1 (en) * | 2005-03-07 | 2006-09-07 | Kotliar Eleonora M | Azithromycin powder for oral suspension compositions |
| US8906823B2 (en) * | 2007-09-24 | 2014-12-09 | Basf Corporation | Pollutant emission control sorbents and methods of manufacture and use |
| TWI468167B (zh) | 2007-11-16 | 2015-01-11 | 威佛（國際）股份有限公司 | 藥學組成物 |
| US8106111B2 (en) | 2009-05-15 | 2012-01-31 | Eastman Chemical Company | Antimicrobial effect of cycloaliphatic diol antimicrobial agents in coating compositions |
| WO2011015219A1 (en) | 2009-08-06 | 2011-02-10 | Shifa Pharmed Industrial Group Co. | Process for the purification of azithromycin by separation from its thermal degradation products and/or isomers |
| RU2512683C2 (ru) * | 2012-06-08 | 2014-04-10 | Общество с ограниченной ответственностью "ВИК-здоровье животных" | Антибактериальная инъекционная фармацевтическая композиция |
| CN117503775A (zh) * | 2017-04-28 | 2024-02-06 | 自由生物有限公司 | 治疗特应性皮炎以及提高活性药物成分稳定性的制剂、方法、试剂盒和剂型 |
| RU2666607C1 (ru) * | 2017-05-03 | 2018-09-11 | Общество С Ограниченной Ответственностью "Вик - Здоровье Животных" | Способ повышения стабильности инъекционной фармацевтической композиции |
| US10792262B1 (en) | 2019-07-29 | 2020-10-06 | Saol International Limited | Stabilized formulations of 4-amino-3-substituted butanoic acid derivatives |
| US11654124B2 (en) | 2019-07-29 | 2023-05-23 | Amneal Pharmaceuticals Llc | Stabilized formulations of 4-amino-3-substituted butanoic acid derivatives |
| CN111450065B (zh) * | 2020-04-22 | 2022-04-01 | 南京嘉晨医药科技有限公司 | 一种阿奇霉素干混悬剂的制备方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| YU43006B (en) * | 1981-03-06 | 1989-02-28 | Pliva Pharm & Chem Works | Process for preparing n-methyl-11-aza-10-deoxo-10-dihydro erythromycin and derivatives thereof |
| US4474768A (en) * | 1982-07-19 | 1984-10-02 | Pfizer Inc. | N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor |
| WO1989002271A1 (en) * | 1987-09-10 | 1989-03-23 | Pfizer | Azithromycin and derivatives as antiprotozoal agents |
| US5605889A (en) | 1994-04-29 | 1997-02-25 | Pfizer Inc. | Method of administering azithromycin |
| AU4399396A (en) * | 1994-12-19 | 1996-07-10 | Russinsky Limited | Compounds |
| US5872104A (en) | 1994-12-27 | 1999-02-16 | Oridigm Corporation | Combinations and methods for reducing antimicrobial resistance |
| CN1205338A (zh) * | 1998-05-08 | 1999-01-20 | 刘万忠 | 阿奇霉素水溶性盐的合成新方法及其在医药上的用途 |
| TW546302B (en) | 1998-05-08 | 2003-08-11 | Biochemie Sa | Improvements in macrolide production |
| US6239112B1 (en) | 1998-07-09 | 2001-05-29 | Merial, Inc. | Water miscible macrolide solutions |
| EP1484062A1 (en) * | 1998-11-30 | 2004-12-08 | Teva Pharmaceutical Industries Limited | Crystalline azithromycin, process for manufacture and pharmaceutical compositions thereof |
| US6239113B1 (en) * | 1999-03-31 | 2001-05-29 | Insite Vision, Incorporated | Topical treatment or prevention of ocular infections |
| IT1313610B1 (it) * | 1999-08-09 | 2002-09-09 | S I F I Societa Ind Farmaceuti | Processo per la preparazione di formulazioni acquose per uso oftalmico |
-
2002
- 2002-10-18 AU AU2002335087A patent/AU2002335087A1/en not_active Abandoned
- 2002-10-18 HU HU0402291A patent/HUP0402291A2/hu unknown
- 2002-10-18 IL IL16139802A patent/IL161398A0/xx unknown
- 2002-10-18 EP EP02801784A patent/EP1446010B1/en not_active Expired - Lifetime
- 2002-10-18 CA CA002463619A patent/CA2463619C/en not_active Expired - Fee Related
- 2002-10-18 DE DE60232005T patent/DE60232005D1/de not_active Expired - Fee Related
- 2002-10-18 AT AT02801784T patent/ATE428403T1/de not_active IP Right Cessation
- 2002-10-18 WO PCT/US2002/033339 patent/WO2003032922A2/en not_active Application Discontinuation
- 2002-10-18 US US10/274,097 patent/US6764997B2/en not_active Expired - Fee Related
- 2002-10-18 PT PT02801784T patent/PT1446010E/pt unknown
- 2002-10-18 DK DK02801784T patent/DK1446010T3/da active
- 2002-10-18 ES ES02801784T patent/ES2324527T3/es not_active Expired - Lifetime
-
2004
- 2004-04-13 US US10/822,773 patent/US20040192622A1/en not_active Abandoned
- 2004-09-07 US US10/936,075 patent/US20050106239A1/en not_active Abandoned
-
2005
- 2005-02-02 HK HK05100860.2A patent/HK1067278A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003032922A3 (en) | 2003-10-16 |
| AU2002335087A1 (en) | 2003-04-28 |
| US20030176369A1 (en) | 2003-09-18 |
| WO2003032922A2 (en) | 2003-04-24 |
| IL161398A0 (en) | 2004-09-27 |
| CA2463619A1 (en) | 2003-04-24 |
| US20040192622A1 (en) | 2004-09-30 |
| HUP0402291A2 (hu) | 2005-03-29 |
| EP1446010B1 (en) | 2009-04-15 |
| EP1446010A2 (en) | 2004-08-18 |
| DE60232005D1 (de) | 2009-05-28 |
| US6764997B2 (en) | 2004-07-20 |
| ATE428403T1 (de) | 2009-05-15 |
| US20050106239A1 (en) | 2005-05-19 |
| EP1446010A4 (en) | 2007-06-13 |
| CA2463619C (en) | 2008-05-06 |
| ES2324527T3 (es) | 2009-08-10 |
| HK1067278A1 (en) | 2005-04-08 |
| PT1446010E (pt) | 2009-06-08 |
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