DK141069B - Analogifremgangsmåde til fremstilling af 1,5,10,10a-tetrahydrothiazolo (3,4-b)isoquinolinderivater eller syreadditionssalte deraf. - Google Patents

Analogifremgangsmåde til fremstilling af 1,5,10,10a-tetrahydrothiazolo (3,4-b)isoquinolinderivater eller syreadditionssalte deraf. Download PDF

Info

Publication number: DK141069B
Authority: DK; Denmark
Prior art keywords: group; tetrahydrothiazolo; tetrahydroisoquinoline; hydrogen atom; reduced pressure
Prior art date: 1975-08-06

Application number

DK353876AA

Other languages

Danish (da)

English (en)

Other versions

DK353876A (no

DK141069C (no

Inventor

Gerard Ponsinet

Daniel Farge

Daniel Reisdorf

Alain Jossin

Original Assignee

Rhone Poulenc Ind

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1975-08-06

Filing date

1976-08-05

Publication date

1980-01-07

1975-08-06 Priority claimed from FR7524523A external-priority patent/FR2320098A1/fr

1976-05-18 Priority claimed from FR7614935A external-priority patent/FR2351655A1/fr

1976-08-05 Application filed by Rhone Poulenc Ind filed Critical Rhone Poulenc Ind

1977-02-07 Publication of DK353876A publication Critical patent/DK353876A/da

1980-01-07 Publication of DK141069B publication Critical patent/DK141069B/da

1980-08-11 Application granted granted Critical

1980-08-11 Publication of DK141069C publication Critical patent/DK141069C/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
- C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Pain & Pain Management (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Rheumatology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK353876AA 1975-08-06 1976-08-05 Analogifremgangsmåde til fremstilling af 1,5,10,10a-tetrahydrothiazolo (3,4-b)isoquinolinderivater eller syreadditionssalte deraf. DK141069B (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
FR7524523		1975-08-06
FR7524523A FR2320098A1 (fr)	1975-08-06	1975-08-06	Nouveaux derives de la thiazilo (3,4-b) isoquinoleine, leur preparation et les compositions qui les contiennent
FR7614935		1976-05-18
FR7614935A FR2351655A1 (fr)	1976-05-18	1976-05-18	Nouveau derive de la thiazolo (3,4-b) isoquinoleine, sa preparation et les compositions qui le contiennent

Publications (3)

Publication Number	Publication Date
DK353876A DK353876A (no)	1977-02-07
DK141069B true DK141069B (da)	1980-01-07
DK141069C DK141069C (no)	1980-08-11

Family

ID=26219017

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK353876AA DK141069B (da)	1975-08-06	1976-08-05	Analogifremgangsmåde til fremstilling af 1,5,10,10a-tetrahydrothiazolo (3,4-b)isoquinolinderivater eller syreadditionssalte deraf.

Country Status (26)

Country	Link
US (1)	US4064247A (no)
JP (1)	JPS5219699A (no)
AR (2)	AR211868A1 (no)
AT (2)	AT350054B (no)
AU (1)	AU505316B2 (no)
CA (1)	CA1073909A (no)
CH (1)	CH612682A5 (no)
CS (1)	CS197276B2 (no)
DE (1)	DE2635516C3 (no)
DK (1)	DK141069B (no)
ES (2)	ES450530A1 (no)
FI (1)	FI60214C (no)
GB (1)	GB1503091A (no)
HU (1)	HU173003B (no)
IE (1)	IE44379B1 (no)
IL (1)	IL50208A (no)
LU (1)	LU75540A1 (no)
MX (1)	MX3639E (no)
NL (1)	NL169076C (no)
NO (1)	NO762729L (no)
NZ (1)	NZ181693A (no)
OA (1)	OA05403A (no)
PL (2)	PL108034B1 (no)
PT (1)	PT65442B (no)
SE (1)	SE422065B (no)
SU (2)	SU629881A3 (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL7800383A (nl) *	1977-01-20	1978-07-24	Rhone Poulenc Ind	Nieuwe isochinolinederivaten, de bereiding ervan en preparaten die de isochinolinederivaten bevatten.
FR2412545A1 (fr) *	1977-12-23	1979-07-20	Rhone Poulenc Ind	Nouveaux derives de l'isoquinoleine, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2412554A2 (fr) *	1977-12-23	1979-07-20	Rhone Poulenc Ind	Nouveaux derives de l'indole, leur preparation et les compositions qui les contiennent
NL7800385A (nl) *	1977-02-04	1978-08-08	Rhone Poulenc Ind	Nieuwe indoolderivaten, werkwijzen ter berei- ding ervan en preparaten die de nieuwe deriva- ten bevatten.
FR2433023A2 (fr) *	1978-08-09	1980-03-07	Rhone Poulenc Ind	Nouveaux derives de l'isoquinoleine, leur preparation et les compositions qui les contiennent
FR2408615A1 (fr) *	1977-11-10	1979-06-08	Rhone Poulenc Ind	Nouveaux derives de l'isoquinoleine, leur preparation et les compositions qui les contiennent
SU797580A3 (ru) *	1977-11-10	1981-01-15	Рон-Пуленк Эндюстри (Фирма)	Способ получени производных изохино-лиНА, иХ СОлЕй, РАцЕМАТОВ или ОпТичЕС-КиХ изОМЕРОВ
FR2456110A2 (fr) *	1979-05-09	1980-12-05	Rhone Poulenc Ind	Nouveaux derives de l'isoquinoleine, leur preparation et les compositions qui les contiennent
NL7908655A (nl) *	1978-12-07	1980-06-10	Rhone Poulenc Ind	Nieuwe thienopyridine-derivaten, de bereiding ervan, alsmede farmaceutische preparaten, die de nieuwe derivaten bevatten.
FR2468613A2 (fr) *	1979-10-29	1981-05-08	Rhone Poulenc Ind	Nouveaux derives de la thienopyridine, leur preparation et les medicaments qui les contiennent
GB2048880A (en) *	1979-05-09	1980-12-17	Rhone Poulenc Ind	Isoquinoline derivatives
HU181232B (en) *	1979-12-04	1983-06-28	Rhone Poulenc Ind	Process for preparing new derivatives of thiazolo-isoquinoline
US4269842A (en) *	1979-12-05	1981-05-26	Rhone-Poulenc Industries	Method for treating rhinoviral complaints
FR2624861B1 (fr) *	1987-12-21	1990-06-01	Delalande Sa	Carbamates tricycliques, leur procede de preparation et leur application en therapeutique
US5059692A (en) *	1989-09-01	1991-10-22	Hiroyoshi Hidaka	Novel compounds exhibiting a vasodilating activity and inhibitory activity for platelet aggregation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3455933A (en) *	1966-11-15	1969-07-15	American Home Prod	Thiazolo and thiazino isoquinoline derivatives
HU170680B (no) *	1973-05-30	1977-08-28

1976
- 1976-07-29 OA OA55901A patent/OA05403A/xx unknown
- 1976-07-29 NL NLAANVRAGE7608444,A patent/NL169076C/xx not_active IP Right Cessation
- 1976-08-02 GB GB32128/76A patent/GB1503091A/en not_active Expired
- 1976-08-03 CS CS765082A patent/CS197276B2/cs unknown
- 1976-08-04 IL IL50208A patent/IL50208A/xx unknown
- 1976-08-04 CA CA258,441A patent/CA1073909A/fr not_active Expired
- 1976-08-05 NZ NZ181693A patent/NZ181693A/xx unknown
- 1976-08-05 JP JP51093548A patent/JPS5219699A/ja active Granted
- 1976-08-05 HU HU76RO00000892A patent/HU173003B/hu unknown
- 1976-08-05 MX MX762133U patent/MX3639E/es unknown
- 1976-08-05 AR AR264233A patent/AR211868A1/es active
- 1976-08-05 AU AU16615/76A patent/AU505316B2/en not_active Expired
- 1976-08-05 SE SE7608808A patent/SE422065B/xx unknown
- 1976-08-05 PT PT65442A patent/PT65442B/pt unknown
- 1976-08-05 US US05/711,963 patent/US4064247A/en not_active Expired - Lifetime
- 1976-08-05 NO NO762729A patent/NO762729L/no unknown
- 1976-08-05 LU LU75540A patent/LU75540A1/xx unknown
- 1976-08-05 DK DK353876AA patent/DK141069B/da not_active IP Right Cessation
- 1976-08-05 CH CH1004176A patent/CH612682A5/xx not_active IP Right Cessation
- 1976-08-05 IE IE1728/76A patent/IE44379B1/en unknown
- 1976-08-06 SU SU762386213A patent/SU629881A3/ru active
- 1976-08-06 PL PL1976191674A patent/PL108034B1/pl unknown
- 1976-08-06 ES ES450530A patent/ES450530A1/es not_active Expired
- 1976-08-06 DE DE2635516A patent/DE2635516C3/de not_active Expired
- 1976-08-06 FI FI762256A patent/FI60214C/fi not_active IP Right Cessation
- 1976-08-06 AT AT586476A patent/AT350054B/de not_active IP Right Cessation
- 1976-08-06 PL PL1976211043A patent/PL108413B1/pl unknown
- 1976-11-04 ES ES452987A patent/ES452987A1/es not_active Expired
1977
- 1977-03-28 AR AR267010A patent/AR211170A1/es active
- 1977-07-26 SU SU772504520A patent/SU635874A3/ru active
1978
- 1978-06-01 AT AT397778A patent/AT351544B/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
GB1503091A (en)	1978-03-08
JPS566435B2 (no)	1981-02-10
IE44379B1 (en)	1981-11-04
NL169076C (nl)	1982-06-01
AT350054B (de)	1979-05-10
FI60214B (fi)	1981-08-31
HU173003B (hu)	1979-01-28
CA1073909A (fr)	1980-03-18
US4064247A (en)	1977-12-20
NL169076B (nl)	1982-01-04
PT65442B (fr)	1978-02-09
MX3639E (es)	1981-04-13
PL191674A1 (pl)	1978-12-18
AU1661576A (en)	1978-02-09
ES450530A1 (es)	1977-11-16
FI762256A (no)	1977-02-07
PL108034B1 (pl)	1980-03-31
SU635874A3 (ru)	1978-11-30
DK353876A (no)	1977-02-07
IL50208A (en)	1978-10-31
ES452987A1 (es)	1977-12-01
CH612682A5 (no)	1979-08-15
SE422065B (sv)	1982-02-15
ATA586476A (de)	1978-10-15
NO762729L (no)	1977-02-08
AU505316B2 (en)	1979-11-15
FI60214C (fi)	1981-12-10
DK141069C (no)	1980-08-11
DE2635516A1 (de)	1977-02-17
NL7608444A (nl)	1977-02-08
AT351544B (de)	1979-07-25
DE2635516B2 (de)	1980-07-24
PT65442A (fr)	1976-09-01
AR211868A1 (es)	1978-03-31
AR211170A1 (es)	1977-10-31
SE7608808L (sv)	1977-02-07
ATA397778A (de)	1979-01-15
IL50208A0 (en)	1976-10-31
IE44379L (en)	1977-02-06
JPS5219699A (en)	1977-02-15
CS197276B2 (en)	1980-04-30
DE2635516C3 (de)	1981-04-16
LU75540A1 (no)	1977-04-20
NZ181693A (en)	1978-06-20
PL108413B1 (en)	1980-04-30
OA05403A (fr)	1981-02-28
SU629881A3 (ru)	1978-10-25

Publication	Publication Date	Title
DK141069B (da)	1980-01-07	Analogifremgangsmåde til fremstilling af 1,5,10,10a-tetrahydrothiazolo (3,4-b)isoquinolinderivater eller syreadditionssalte deraf.
JPH0737460B2 (ja)	1995-04-26	ピラノインドリジン誘導体及びその製造法
FR2554719A1 (fr)	1985-05-17	Medicaments a base de nouveaux derives de la vinyl-6 furo-(3,4-c)-pyridine
US4196292A (en)	1980-04-01	6-Substituted amiloride derivatives
FR2638161A1 (fr)	1990-04-27	Nouvelles benzoyl-2 imidazo (1,2-a) pyridines et leurs sels, leur procede de preparation, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant
Seeman et al.	1976	The iodomethylation of nicotine. An unusual example of competitive nitrogen alkylation
Cain et al.	1976	Potential antitumor agents. 19. Multiply substituted 4'-(9-acridinylamino) methanesulfonanilides
Okafor	1973	Heterocyclic series. VII. Use of Kaufmann's reaction as a route to o-aminomercaptopyridines
JPS6040422B2 (ja)	1985-09-11	置換１‐アルキルチオフエニル―２，３，４，５―テトラヒドロ―１ｈ―３―ベンズアゼピン化合物
US4124587A (en)	1978-11-07	4-Hydroxy-3-sulfinyl-quinolin-2(1H)-ones
US6258829B1 (en)	2001-07-10	Cycloalka[b]pyridine-3-carbonylguanidine derivatives, process for producing the same, and drugs containing the same
Child et al.	1931	V.—1-ω-Halogenoalkyl iso quinolines and their derivatives
CH630638A5 (fr)	1982-06-30	Nouveaux derives de la pyrido-(2,2-b)benzothiazepine-(1,5) substitues en position 5.
NO780202L (no)	1978-07-21	Fremgangsmaate for fremstilling av nye derivater av isokinolin
CS227001B2 (en)	1984-04-16	Method of preparing thiazoloisoquinoline derivatives
McCoubrey et al.	1949	148. Contributions to the chemistry of iso quinolines. Part I. The synthesis of diamino-1-phenylisoquinoline methiodides in a search for new trypanocides, with some observations on the nitration of 1-phenylisoquinoline
JPS63166876A (ja)	1988-07-11	ピリドンカルボン酸誘導体
JPS6229585A (ja)	1987-02-07	エーテル化若しくはエステル化しうるジヒドロキシ基により位置２で置換された４―ｏｈキノリンカルボン酸の新規の誘導体、その製造方法、及び医薬としてのその使用
NO783770L (no)	1979-05-11	Nye derivater av isokinolin.
Balenovic et al.	1952	Synthesis of Aminomethylglyoxal Derivatives
JP2585086B2 (ja)	1997-02-26	ジアザビシクロアルカン誘導体
CS197277B2 (cs)	1980-04-30	Zpustli) výroby nových l,5,19,10a-tetrahydroihiazolo- [ 3,4-b jisochinolinových derivátů
JPS5993080A (ja)	1984-05-29	１，５−ナフチリジンカルボン酸誘導体
JPS5973589A (ja)	1984-04-25	Ｃ−ホモ−９−オキサエルゴリンの新誘導体及びそれらの塩類、これらの製造法並びにそれらを含有する薬剤
KR800000851B1 (ko)	1980-08-26	티아졸로[3.4-b] 이소퀴놀린 유도체의 제법

Legal Events

Date	Code	Title	Description
1984-03-24	PBP	Patent lapsed