DK1404844T3 - Fremgangsmåde til fremstilling af 2,4-dideoxyhexoser og 2,4,6-trideoxyhyxoser - Google Patents
Fremgangsmåde til fremstilling af 2,4-dideoxyhexoser og 2,4,6-trideoxyhyxoserInfo
- Publication number
- DK1404844T3 DK1404844T3 DK02746200T DK02746200T DK1404844T3 DK 1404844 T3 DK1404844 T3 DK 1404844T3 DK 02746200 T DK02746200 T DK 02746200T DK 02746200 T DK02746200 T DK 02746200T DK 1404844 T3 DK1404844 T3 DK 1404844T3
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- substituted
- hyxoses
- trideoxy
- hexoses
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 150000002402 hexoses Chemical class 0.000 title 1
- HNPRLDIJKHZNSL-RITPCOANSA-N (3s,5s)-3,5,6-trihydroxyhexanal Chemical compound OC[C@@H](O)C[C@H](O)CC=O HNPRLDIJKHZNSL-RITPCOANSA-N 0.000 abstract 3
- 150000001299 aldehydes Chemical class 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 150000001728 carbonyl compounds Chemical class 0.000 abstract 2
- 239000011541 reaction mixture Substances 0.000 abstract 2
- 102000001390 Fructose-Bisphosphate Aldolase Human genes 0.000 abstract 1
- 108010068561 Fructose-Bisphosphate Aldolase Proteins 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- DFVFTMTWCUHJBL-BQBZGAKWSA-N statine Chemical compound CC(C)C[C@H](N)[C@@H](O)CC(O)=O DFVFTMTWCUHJBL-BQBZGAKWSA-N 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/02—Monosaccharides
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL1018525A NL1018525C2 (nl) | 2001-07-12 | 2001-07-12 | Werkwijze voor de bereiding van 2,4-dideoxyhexosen en 2,4,6-trideoxyhexosen. |
| NL1019622A NL1019622C2 (nl) | 2001-12-20 | 2001-12-20 | Werkwijze voor de bereiding van 2,4-dideoxyhexosen en 2,4,6-trideoxyhexosen. |
| PCT/NL2002/000450 WO2003006656A2 (en) | 2001-07-12 | 2002-07-09 | Process for the preparation of 2,4-dideoxyhexoses and 2,4,6-trideoxyhexoses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1404844T3 true DK1404844T3 (da) | 2007-06-04 |
Family
ID=26643375
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK02746200T DK1404844T3 (da) | 2001-07-12 | 2002-07-09 | Fremgangsmåde til fremstilling af 2,4-dideoxyhexoser og 2,4,6-trideoxyhyxoser |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US6964863B2 (da) |
| EP (1) | EP1404844B1 (da) |
| JP (1) | JP4248392B2 (da) |
| CN (1) | CN1300132C (da) |
| AT (1) | ATE356215T1 (da) |
| CA (1) | CA2448517A1 (da) |
| DE (1) | DE60218678T2 (da) |
| DK (1) | DK1404844T3 (da) |
| ES (1) | ES2282433T3 (da) |
| HU (1) | HU228734B1 (da) |
| MX (1) | MXPA04000310A (da) |
| WO (1) | WO2003006656A2 (da) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7414119B2 (en) | 2002-09-20 | 2008-08-19 | Verenium Corporation | Aldolases, nucleic acids encoding them and methods for making and using them |
| WO2005098012A1 (ja) * | 2004-03-29 | 2005-10-20 | Mitsui Chemicals, Inc. | キラルなヒドロキシアルデヒド化合物の製造方法 |
| KR100807523B1 (ko) | 2004-12-31 | 2008-02-26 | 주식회사유한양행 | 광학 활성 디올 유도체의 신규 제조방법 |
| WO2007137816A1 (en) * | 2006-05-30 | 2007-12-06 | Dsm Ip Assets B.V. | Process for the preparation of epoxide intermediates for pharmaceutical compounds such as statins |
| ES2523404T3 (es) | 2007-08-03 | 2014-11-25 | Pfizer Products Inc. | Procedimiento de preparación de compuestos quirales |
| AU2009207721B2 (en) * | 2008-01-23 | 2014-10-23 | Lek Pharmaceuticals D.D. | ((2S,4R)-4,6-dihydroxytetrahydro-2H-pyran-2-yl)methyl carboxylate and process for the production employing a 2-deoxyribose-5-phosphate aldolase |
| MX363563B (es) | 2011-12-09 | 2019-03-27 | Dsm Sinochem Pharm Nl Bv | Proceso para la preparación de un tioprecursor de estatinas. |
| MX359424B (es) | 2011-12-09 | 2018-09-12 | Dsm Sinochem Pharm Nl Bv | Proceso para la preparación de un precursor de estatina. |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5278313A (en) * | 1992-03-27 | 1994-01-11 | E. R. Squibb & Sons, Inc. | Process for the preparation of 1,3-dioxane derivatives useful in the preparation of HMG-COA reductase inhibitors |
| US5795749A (en) * | 1995-04-05 | 1998-08-18 | The Scripps Research Institution | Use of 2-deoxyribose-5-phosphate aldolase to prepare 2-deoxyfucose, analogues and derivatives |
| ATE266656T1 (de) | 1998-08-05 | 2004-05-15 | Kaneka Corp | Verfahren zur herstellung optisch aktiver 2-(6- (hydroxymethyl)-1,3-dioxan-4-yl) -essigsäure- derivate |
-
2002
- 2002-07-09 DK DK02746200T patent/DK1404844T3/da active
- 2002-07-09 WO PCT/NL2002/000450 patent/WO2003006656A2/en active IP Right Grant
- 2002-07-09 JP JP2003512413A patent/JP4248392B2/ja not_active Expired - Fee Related
- 2002-07-09 ES ES02746200T patent/ES2282433T3/es not_active Expired - Lifetime
- 2002-07-09 MX MXPA04000310A patent/MXPA04000310A/es active IP Right Grant
- 2002-07-09 AT AT02746200T patent/ATE356215T1/de not_active IP Right Cessation
- 2002-07-09 EP EP02746200A patent/EP1404844B1/en not_active Expired - Lifetime
- 2002-07-09 CA CA002448517A patent/CA2448517A1/en not_active Abandoned
- 2002-07-09 HU HU0401577A patent/HU228734B1/hu not_active IP Right Cessation
- 2002-07-09 US US10/481,303 patent/US6964863B2/en not_active Expired - Lifetime
- 2002-07-09 DE DE60218678T patent/DE60218678T2/de not_active Expired - Lifetime
- 2002-07-09 CN CNB028139429A patent/CN1300132C/zh not_active Expired - Lifetime
-
2005
- 2005-08-17 US US11/206,574 patent/US7439046B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20050287650A1 (en) | 2005-12-29 |
| EP1404844A2 (en) | 2004-04-07 |
| DE60218678D1 (de) | 2007-04-19 |
| ATE356215T1 (de) | 2007-03-15 |
| MXPA04000310A (es) | 2004-05-04 |
| EP1404844B1 (en) | 2007-03-07 |
| CA2448517A1 (en) | 2003-01-23 |
| HUP0401577A3 (en) | 2010-03-29 |
| CN1526019A (zh) | 2004-09-01 |
| DE60218678T2 (de) | 2008-02-14 |
| JP2005500838A (ja) | 2005-01-13 |
| JP4248392B2 (ja) | 2009-04-02 |
| HU228734B1 (hu) | 2013-05-28 |
| US6964863B2 (en) | 2005-11-15 |
| WO2003006656A3 (en) | 2003-12-11 |
| CN1300132C (zh) | 2007-02-14 |
| ES2282433T3 (es) | 2007-10-16 |
| WO2003006656A2 (en) | 2003-01-23 |
| US7439046B2 (en) | 2008-10-21 |
| US20040171125A1 (en) | 2004-09-02 |
| HUP0401577A2 (hu) | 2004-11-29 |
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