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DK1399438T3 - Hidtil ukendte heteroarylderivater samt fremstilling og anvendelse heraf - Google Patents

Hidtil ukendte heteroarylderivater samt fremstilling og anvendelse heraf

Info

Publication number
DK1399438T3
DK1399438T3 DK02742849T DK02742849T DK1399438T3 DK 1399438 T3 DK1399438 T3 DK 1399438T3 DK 02742849 T DK02742849 T DK 02742849T DK 02742849 T DK02742849 T DK 02742849T DK 1399438 T3 DK1399438 T3 DK 1399438T3
Authority
DK
Denmark
Prior art keywords
preparation
heteroaryl derivatives
novel heteroaryl
disorders
disorder
Prior art date
Application number
DK02742849T
Other languages
Danish (da)
English (en)
Inventor
Mario Rottlaender
Ejner Knud Moltzen
Ivan Mikkelsen
Thomas Ruhland
Kim Andersen
Christian Krog-Jensen
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Application granted granted Critical
Publication of DK1399438T3 publication Critical patent/DK1399438T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32Alcohol-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK02742849T 2001-06-29 2002-06-27 Hidtil ukendte heteroarylderivater samt fremstilling og anvendelse heraf DK1399438T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200101036 2001-06-29
PCT/DK2002/000435 WO2003002556A1 (en) 2001-06-29 2002-06-27 Novel heteroaryl derivatives, their preparation and use

Publications (1)

Publication Number Publication Date
DK1399438T3 true DK1399438T3 (da) 2006-04-18

Family

ID=8160598

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02742849T DK1399438T3 (da) 2001-06-29 2002-06-27 Hidtil ukendte heteroarylderivater samt fremstilling og anvendelse heraf

Country Status (26)

Country Link
US (2) US20040248883A1 (de)
EP (1) EP1399438B1 (de)
JP (1) JP2004535449A (de)
KR (1) KR20040019026A (de)
CN (1) CN1310909C (de)
AT (1) ATE312094T1 (de)
AU (1) AU2002344949B2 (de)
BG (1) BG108531A (de)
BR (1) BR0210401A (de)
CA (1) CA2451228A1 (de)
CZ (1) CZ2004156A3 (de)
DE (1) DE60207857T2 (de)
DK (1) DK1399438T3 (de)
EA (1) EA006203B1 (de)
ES (1) ES2252471T3 (de)
HU (1) HUP0400344A2 (de)
IL (1) IL158828A0 (de)
IS (1) IS2425B (de)
MX (1) MXPA03011769A (de)
NO (1) NO326514B1 (de)
NZ (1) NZ529460A (de)
PL (1) PL365249A1 (de)
SI (1) SI1399438T1 (de)
SK (1) SK652004A3 (de)
UA (1) UA75407C2 (de)
WO (1) WO2003002556A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ2004155A3 (cs) * 2001-06-29 2004-07-14 H. Lundbeck A/S Název neuveden
EP1408976B3 (de) * 2001-07-20 2010-08-25 Psychogenics Inc. Behandlung von hyperaktivitätsstörungen und aufmerksamkeitsdefiziten
US7262293B2 (en) * 2003-07-02 2007-08-28 Corus Pharma Aztreonam L-lysine and methods for the preparation thereof
US7160888B2 (en) 2003-08-22 2007-01-09 Warner Lambert Company Llc [1,8]naphthyridin-2-ones and related compounds for the treatment of schizophrenia
WO2006056600A1 (en) 2004-11-26 2006-06-01 Janssen Pharmaceutica N.V. Isoxazoline-indole derivatives with an improved antipsychotic and anxiolytic a ivity
WO2011080341A1 (en) 2010-01-04 2011-07-07 Enantia, S.L. Process for the preparation of rivaroxaban and intermediates thereof
KR100986301B1 (ko) 2010-04-12 2010-10-07 아주대학교산학협력단 테트라하이드로퀴놀린 유도체로부터 유래한 티오펜-축합고리 싸이클로펜타디에닐 4족 금속 화합물 및 이를 이용한 올레핀 중합
US8916662B2 (en) 2010-04-12 2014-12-23 Lotte Chemical Corporation Method for preparing olefin-diene copolymer using transition metal compound containing thiophene-fused cyclopentadienyl ligand
CN102834422B (zh) 2010-04-12 2015-03-18 乐天化学株式会社 使用包含噻吩稠合的环戊二烯基配体的过渡金属化合物制备聚丙烯的方法
EP2559710B1 (de) 2010-04-12 2016-07-13 Lotte Chemical Corporation Katalysatorzusammensetzung zur polymerisierung von olefinen und verfahren zur herstellung von olefinen damit
WO2011129592A2 (ko) 2010-04-12 2011-10-20 호남석유화학 주식회사 올레핀 중합용 담지 촉매 및 이를 사용한 폴리올레핀의 제조방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2667068B1 (fr) * 1990-09-26 1994-09-09 Adir Nouvelles amines alkyl heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
CZ2004155A3 (cs) * 2001-06-29 2004-07-14 H. Lundbeck A/S Název neuveden

Also Published As

Publication number Publication date
UA75407C2 (en) 2006-04-17
SK652004A3 (en) 2004-09-08
EP1399438B1 (de) 2005-12-07
EP1399438A1 (de) 2004-03-24
IS2425B (is) 2008-10-15
ATE312094T1 (de) 2005-12-15
NO20035673L (no) 2003-12-18
US7393845B2 (en) 2008-07-01
IL158828A0 (en) 2004-05-12
IS7021A (is) 2003-11-10
HUP0400344A2 (hu) 2004-09-28
DE60207857T2 (de) 2006-07-20
WO2003002556A1 (en) 2003-01-09
CZ2004156A3 (cs) 2004-05-12
AU2002344949B2 (en) 2007-05-24
BG108531A (bg) 2004-08-31
HK1068622A1 (en) 2005-04-29
KR20040019026A (ko) 2004-03-04
EA200400102A1 (ru) 2004-04-29
CA2451228A1 (en) 2003-01-09
CN1520410A (zh) 2004-08-11
PL365249A1 (en) 2004-12-27
NO326514B1 (no) 2008-12-22
JP2004535449A (ja) 2004-11-25
NZ529460A (en) 2005-09-30
EA006203B1 (ru) 2005-10-27
CN1310909C (zh) 2007-04-18
ES2252471T3 (es) 2006-05-16
US20040248883A1 (en) 2004-12-09
US20080027071A1 (en) 2008-01-31
DE60207857D1 (de) 2006-01-12
BR0210401A (pt) 2004-08-17
NO20035673D0 (no) 2003-12-18
MXPA03011769A (es) 2004-04-02
SI1399438T1 (sl) 2006-04-30

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